Paula Durante

Summary

Country: Venezuela

Publications

  1. doi request reprint Effect of uric acid on nephrotoxicity induced by mercuric chloride in rats
    Paula Durante
    Centro de Investigaciones Biomedicas, IVIC Zulia, Maracaibo, Venezuela
    Toxicol Ind Health 26:163-74. 2010
  2. doi request reprint Effect of uric acid on hypertension progression in spontaneously hypertensive rats
    Paula Durante
    Centro de Investigaciones Biomedicas, IVIC Zulia, Maracaibo, Venezuela
    Life Sci 86:957-64. 2010
  3. doi request reprint Effect of uric acid on gentamicin-induced nephrotoxicity in rats - role of matrix metalloproteinases 2 and 9
    Freddy Romero
    Centre for Biomedical Investigations, IVIC Zulia, Maracaibo, Venezuela
    Basic Clin Pharmacol Toxicol 105:416-24. 2009

Collaborators

  • Freddy Romero
  • Gustavo Parra
  • Mariela Pérez
  • Maribel Chávez

Detail Information

Publications3

  1. doi request reprint Effect of uric acid on nephrotoxicity induced by mercuric chloride in rats
    Paula Durante
    Centro de Investigaciones Biomedicas, IVIC Zulia, Maracaibo, Venezuela
    Toxicol Ind Health 26:163-74. 2010
    ..Our results indicate that UA could play a beneficial role against HgCl(2) toxicity by preventing systemic and renal oxidative stress and tissue damage...
  2. doi request reprint Effect of uric acid on hypertension progression in spontaneously hypertensive rats
    Paula Durante
    Centro de Investigaciones Biomedicas, IVIC Zulia, Maracaibo, Venezuela
    Life Sci 86:957-64. 2010
    ..We investigated the effects of soluble uric acid (UA) on the development of hypertension in spontaneously hypertensive rats (SHRs), using Wistar-Kyoto rats (WKY) as normotensive controls...
  3. doi request reprint Effect of uric acid on gentamicin-induced nephrotoxicity in rats - role of matrix metalloproteinases 2 and 9
    Freddy Romero
    Centre for Biomedical Investigations, IVIC Zulia, Maracaibo, Venezuela
    Basic Clin Pharmacol Toxicol 105:416-24. 2009
    ..The results indicate that uric acid worsens gentamicin-induced nephrotoxicity. The mechanism is likely to implicate down-regulation of MMP-9...