Anuj -, Arivazhagan L, Venkatraman G, Rayala S. Increased Expression of MicroRNA 551a by c-Fos Reduces Focal Adhesion Kinase Levels and Blocks Tumorigenesis. Mol Cell Biol. 2019;39: pubmed publisher
..All of these results showed that miR-551a can be of clinical relevance in understanding the regulation of FAK in breast tumorigenesis. ..
Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala S. Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells. Mol Cell Biol. 2016;36:1354-65 pubmed publisher
Kumar A, Jagadeeshan S, Pitani R, Ramshankar V, Venkitasamy K, Venkatraman G, et al
. Snail-Modulated MicroRNA 493 Forms a Negative Feedback Loop with the Insulin-Like Growth Factor 1 Receptor Pathway and Blocks Tumorigenesis. Mol Cell Biol. 2017;37: pubmed publisher
Kumar A, Jagadeeshan S, Subramanian A, Chidambaram S, Surabhi R, Singhal M, et al
. Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor. J Biol Chem. 2016;291:12310-21 pubmed publisher
..Interestingly, the observed induction of TH was compromised on silencing of MTA1. The underlying molecular mechanism of MTA1 induction by G-CSF was proved to be through induction of c-Fos and its recruitment to the MTA1 promoter. ..
Raghavan S, Manogaran P, Gadepalli Narasimha K, Kalpattu Kuppusami B, Mariyappan P, Gopalakrishnan A, et al
. Synthesis and anticancer activity of novel curcumin-quinolone hybrids. Bioorg Med Chem Lett. 2015;25:3601-5 pubmed publisher
..Further experiments on generation of reactive oxygen species (ROS) and cell cycle analysis revealed that these hybrids induce apoptosis by ROS generation and arrest cell cycle progression in S and G2/M phase. ..
Kesavan A, Ilaiyaraja P, Sofi Beaula W, Veena Kumari V, Sugin Lal J, Arunkumar C, et al
. Tumor targeting using polyamidoamine dendrimer-cisplatin nanoparticles functionalized with diglycolamic acid and herceptin. Eur J Pharm Biopharm. 2015;96:255-63 pubmed publisher
..Collectively, these results indicate that herceptin targeted DGA functionalized PAMAM-cisplatin conjugates serve as better anti-tumor agents than individual therapeutic agents. ..
Ravi M, Tentu S, Baskar G, Rohan Prasad S, Raghavan S, Jayaprakash P, et al
. Molecular mechanism of anti-cancer activity of phycocyanin in triple-negative breast cancer cells. BMC Cancer. 2015;15:768 pubmed publisher
..Taken together, these findings demonstrate, for the first time, that PC may be a promising anti-neoplastic agent for treatment of triple negative breast cancers. ..
Raghavan S, Venkatraman G, Rayala S. Cloning and functional characterization of human Pak1 promoter by steroid hormones. Gene. 2018;646:120-128 pubmed publisher
..To our knowledge, this is the first study to report the detailed characterization and transcriptional regulation of the human Pak1 promoter by steroid hormones. ..