Ganesh Venkatraman

Summary

Publications

  1. Anuj -, Arivazhagan L, Venkatraman G, Rayala S. Increased Expression of MicroRNA 551a by c-Fos Reduces Focal Adhesion Kinase Levels and Blocks Tumorigenesis. Mol Cell Biol. 2019;39: pubmed publisher
    ..All of these results showed that miR-551a can be of clinical relevance in understanding the regulation of FAK in breast tumorigenesis. ..
  2. Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala S. Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells. Mol Cell Biol. 2016;36:1354-65 pubmed publisher
  3. Kumar A, Jagadeeshan S, Pitani R, Ramshankar V, Venkitasamy K, Venkatraman G, et al. Snail-Modulated MicroRNA 493 Forms a Negative Feedback Loop with the Insulin-Like Growth Factor 1 Receptor Pathway and Blocks Tumorigenesis. Mol Cell Biol. 2017;37: pubmed publisher
  4. Kumar A, Jagadeeshan S, Subramanian A, Chidambaram S, Surabhi R, Singhal M, et al. Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor. J Biol Chem. 2016;291:12310-21 pubmed publisher
    ..Interestingly, the observed induction of TH was compromised on silencing of MTA1. The underlying molecular mechanism of MTA1 induction by G-CSF was proved to be through induction of c-Fos and its recruitment to the MTA1 promoter. ..
  5. Raghavan S, Manogaran P, Gadepalli Narasimha K, Kalpattu Kuppusami B, Mariyappan P, Gopalakrishnan A, et al. Synthesis and anticancer activity of novel curcumin-quinolone hybrids. Bioorg Med Chem Lett. 2015;25:3601-5 pubmed publisher
    ..Further experiments on generation of reactive oxygen species (ROS) and cell cycle analysis revealed that these hybrids induce apoptosis by ROS generation and arrest cell cycle progression in S and G2/M phase. ..
  6. Kesavan A, Ilaiyaraja P, Sofi Beaula W, Veena Kumari V, Sugin Lal J, Arunkumar C, et al. Tumor targeting using polyamidoamine dendrimer-cisplatin nanoparticles functionalized with diglycolamic acid and herceptin. Eur J Pharm Biopharm. 2015;96:255-63 pubmed publisher
    ..Collectively, these results indicate that herceptin targeted DGA functionalized PAMAM-cisplatin conjugates serve as better anti-tumor agents than individual therapeutic agents. ..
  7. Ravi M, Tentu S, Baskar G, Rohan Prasad S, Raghavan S, Jayaprakash P, et al. Molecular mechanism of anti-cancer activity of phycocyanin in triple-negative breast cancer cells. BMC Cancer. 2015;15:768 pubmed publisher
    ..Taken together, these findings demonstrate, for the first time, that PC may be a promising anti-neoplastic agent for treatment of triple negative breast cancers. ..
  8. Raghavan S, Venkatraman G, Rayala S. Cloning and functional characterization of human Pak1 promoter by steroid hormones. Gene. 2018;646:120-128 pubmed publisher
    ..To our knowledge, this is the first study to report the detailed characterization and transcriptional regulation of the human Pak1 promoter by steroid hormones. ..