The role of long-range intermolecular interactions in discovery of new drugsNevena Veljkovic
University of Belgrade, Institute of Nuclear Sciences Vinca, Center for Multidisciplinary Research, P O Box 522, 11001 Belgrade, Serbia 381 11 2453 686 381 11 3440 100
Expert Opin Drug Discov 6:1263-70. 2011
..The addition of the computer-aided design techniques based on the EIIP/AQVN concept to the research and development will lead not only to a significant reduction in cost but also to an acceleration in the development of new drugs...
Identification of hemagglutinin structural domain and polymorphisms which may modulate swine H1N1 interactions with human receptorVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, PO Box 522, 11001 Belgrade, Serbia
BMC Struct Biol 9:62. 2009
..Here we have studied properties of hemagglutinin of A/H1N1 which may modulate virus/receptor interaction...
Characterization of conserved properties of hemagglutinin of H5N1 and human influenza viruses: possible consequences for therapy and infection controlVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, P O Box 522, 11001 Belgrade, Serbia
BMC Struct Biol 9:21. 2009
..Here we compare informational and structural properties of the hemagglutinin (HA) of H5N1 virus and human influenza virus subtypes, which are important for the receptor/virus interaction...
Discovery of new therapeutic targets by the informational spectrum methodNevena Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, Belgrade, Serbia
Curr Protein Pept Sci 9:493-506. 2008
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AIDS vaccine: efficacy, safety and ethicsVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, 11001 Belgrade, Serbia
Vaccine 26:3072-7. 2008
..We comment on the efficacy, safety and ethics of AIDS vaccine, and the urgent need for a new strategy for AIDS vaccine development...
Antibodies reactive with C-terminus of the second conserved region of HIV-1gp120 as possible prognostic marker and therapeutic agent for HIV diseaseNevena Veljkovic
Laboratory for Multidisciplinary Research, Institute of Nuclear Sciences, P O Box 522, 11001 Belgrade, Serbia and Montenegro
J Clin Virol 31:S39-44. 2004
..Based on these findings we proposed the anti-NTM antibodies as useful prognostic marker for HIV disease...
Assessment of hepatitis C virus protein sequences with regard to interferon/ribavirin combination therapy response in patients with HCV genotype 1bSanja Glisic
Centre for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, Belgrade, Serbia
Protein J 31:129-36. 2012
..On the basis of these results, a simple bioinformatics criterion that could be useful in assessment of the response of HCV-infected patients to the combination therapy has been proposed...
Safety and ethical consideration of AIDS vaccineVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, Belgrade, Yugoslavia
Int Rev Immunol 23:465-86. 2004
..This situation opens a serious question about the safety of vectored AIDS vaccine and the ethics of their trials in humans...
Novel Phylogenetic Algorithm to Monitor Human Tropism in Egyptian H5N1-HPAIV Reveals Evolution toward Efficient Human-to-Human TransmissionVladimir R Perovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade, Belgrade, Serbia
PLoS ONE 8:e61572. 2013
..The extensive evolution of Egyptian H5N1-HPAIV towards a preferential human tropism underlines an urgent need to closely monitor these viruses with respect to molecular determinants of virulence...
Recombination property of the HIV-1 gp120 geneJelena Prljic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, Belgrade, Yugoslavia
Int Rev Immunol 23:447-54. 2004
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Application of VIP/NTM-reactive natural antibodies in therapy of HIV diseaseVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, Belgrade, Yugoslavia
Int Rev Immunol 23:437-45. 2004
..These findings point out the VIP/C2-reactive natural antibodies as an important agent for immunotherapy of HIV disease...
Simple criterion for selection of flavonoid compounds with anti-HIV activityVeljko Veljkovic
Centre for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, PO Box 522, 11001 Belgrade, Serbia
Bioorg Med Chem Lett 17:1226-32. 2007
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Molecular makeup of HIV-1 envelope proteinVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, Belgrade, Yugoslavia
Int Rev Immunol 23:383-411. 2004
..Here we described some of these properties of HIV-1 gp120 that represent the main obstacle in the development of effective and safe AIDS vaccine...
AIDSVAX results: an important open questionVeljko Veljkovic
Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, P O Box 522, 11001 Belgrade, Yugoslavia
Vaccine 21:3528-9. 2003
..Results of the recently finished clinical trial of AIDSVAX represent a good base for this important analysis...