Ganna Vashchenko

Summary

Publications

  1. pmc Multi-copper oxidases and human iron metabolism
    Ganna Vashchenko
    Department of Cellular and Physiological Sciences, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T1Z3, Canada
    Nutrients 5:2289-313. 2013
  2. doi request reprint Functional role of the putative iron ligands in the ferroxidase activity of recombinant human hephaestin
    Ganna Vashchenko
    Department of Biochemistry and Molecular Biology, Centre for Blood Research, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC, V6T1Z3, Canada
    J Biol Inorg Chem 17:1187-95. 2012
  3. doi request reprint Oxidation of organic and biogenic amines by recombinant human hephaestin expressed in Pichia pastoris
    Ganna Vashchenko
    Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada
    Arch Biochem Biophys 514:50-6. 2011

Detail Information

Publications3

  1. pmc Multi-copper oxidases and human iron metabolism
    Ganna Vashchenko
    Department of Cellular and Physiological Sciences, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T1Z3, Canada
    Nutrients 5:2289-313. 2013
    ..In this manuscript, we review the biochemical and biological properties of the three human MCOs and discuss their potential roles in human iron homeostasis...
  2. doi request reprint Functional role of the putative iron ligands in the ferroxidase activity of recombinant human hephaestin
    Ganna Vashchenko
    Department of Biochemistry and Molecular Biology, Centre for Blood Research, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC, V6T1Z3, Canada
    J Biol Inorg Chem 17:1187-95. 2012
    ..Kinetic analysis of ferroxidation rates of wild-type rhHp and mutants demonstrated the important roles of hephaestin residues E960 and H965 in the observed ferroxidase activity...
  3. doi request reprint Oxidation of organic and biogenic amines by recombinant human hephaestin expressed in Pichia pastoris
    Ganna Vashchenko
    Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada
    Arch Biochem Biophys 514:50-6. 2011
    ..However, in contrast to ceruloplasmin, hephaestin was incapable of direct oxidation of adrenaline and dopamine implying a difference in biological substrate specificities between these two homologous ferroxidases...