Joep J van Oosterhout

Summary

Publications

  1. pmc Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi
    Joep J van Oosterhout
    Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi
    PLoS ONE 7:e42029. 2012
  2. ncbi request reprint The benefit of supplementary feeding for wasted Malawian adults initiating ART
    Joep J van Oosterhout
    Department of Medicine, University of Malawi, Blantyre, Malawi
    AIDS Care 22:737-42. 2010
  3. pmc Which health care facilities do adult Malawian antiretroviral therapy patients utilize during intercurrent illness?A cross sectional study
    Caroline Masangalawe
    Department of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi
    BMC Health Serv Res 11:345. 2011
  4. pmc A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi
    Camilla Rothe
    Department of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi
    PLoS ONE 8:e67311. 2013
  5. ncbi request reprint Evaluation of antiretroviral therapy results in a resource-poor setting in Blantyre, Malawi
    Joep J van Oosterhout
    Department of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi
    Trop Med Int Health 10:464-70. 2005
  6. pmc Supplementary feeding in the care of the wasted HIV infected patient
    Mark Manary
    Department of Public Health, College of Medicine, University of Malawi
    Malawi Med J 22:46-8. 2010
  7. ncbi request reprint Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities
    Newton Chagoma
    Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine
    Trans R Soc Trop Med Hyg 107:615-9. 2013
  8. pmc Mitochondrial DNA subhaplogroups L0a2 and L2a modify susceptibility to peripheral neuropathy in malawian adults on stavudine containing highly active antiretroviral therapy
    Elizabeth Kampira
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa and Department of Pathology, Department of Medicine, and Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Malawi
    J Acquir Immune Defic Syndr 63:647-52. 2013
  9. ncbi request reprint Adherence to antiretroviral therapy in patients receiving free treatment from a government hospital in Blantyre, Malawi
    David J Bell
    Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi
    J Acquir Immune Defic Syndr 45:560-3. 2007
  10. pmc Evidence of improving antiretroviral therapy treatment delays: an analysis of eight years of programmatic outcomes in Blantyre, Malawi
    Derek J Sloan
    Malawi Liverpool Wellcome Trust and Liverpool School of Tropical Medicine, Chichiri 3, PO 30096, Blantyre, Malawi
    BMC Public Health 13:490. 2013

Collaborators

Detail Information

Publications18

  1. pmc Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi
    Joep J van Oosterhout
    Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi
    PLoS ONE 7:e42029. 2012
    ....
  2. ncbi request reprint The benefit of supplementary feeding for wasted Malawian adults initiating ART
    Joep J van Oosterhout
    Department of Medicine, University of Malawi, Blantyre, Malawi
    AIDS Care 22:737-42. 2010
    ..Supplementary food use was not directly associated with improved survival...
  3. pmc Which health care facilities do adult Malawian antiretroviral therapy patients utilize during intercurrent illness?A cross sectional study
    Caroline Masangalawe
    Department of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi
    BMC Health Serv Res 11:345. 2011
    ..Overcrowding, long waiting times and living far away from the clinic may affect the extent to which patients use their ART clinic for intercurrent illnesses...
  4. pmc A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi
    Camilla Rothe
    Department of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi
    PLoS ONE 8:e67311. 2013
    ..Fluconazole monotherapy is frequently recommended in national guidelines but is a fungistatic drug compromised by uncertainty over optimal dosing and a paucity of clinical end-point outcome data...
  5. ncbi request reprint Evaluation of antiretroviral therapy results in a resource-poor setting in Blantyre, Malawi
    Joep J van Oosterhout
    Department of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi
    Trop Med Int Health 10:464-70. 2005
    ..The only ART was a fixed drug combination of stavudine, lamivudine and nevirapine...
  6. pmc Supplementary feeding in the care of the wasted HIV infected patient
    Mark Manary
    Department of Public Health, College of Medicine, University of Malawi
    Malawi Med J 22:46-8. 2010
    ..Further research is urgently needed concerning the widespread practice of supplementary feeding in HIV/AIDS care to most effectively utilize this intervention...
  7. ncbi request reprint Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities
    Newton Chagoma
    Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine
    Trans R Soc Trop Med Hyg 107:615-9. 2013
    ..Stavudine is still widely used in under-resourced settings such as Malawi due to its low price. It frequently causes peripheral neuropathy and lipodystrophy and increases the risk of lactic acidosis and other high lactate syndromes...
  8. pmc Mitochondrial DNA subhaplogroups L0a2 and L2a modify susceptibility to peripheral neuropathy in malawian adults on stavudine containing highly active antiretroviral therapy
    Elizabeth Kampira
    Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa and Department of Pathology, Department of Medicine, and Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Malawi
    J Acquir Immune Defic Syndr 63:647-52. 2013
    ..We investigated mtDNA haplogroups and their role in susceptibility to stavudine-induced peripheral in Malawian patients on ART...
  9. ncbi request reprint Adherence to antiretroviral therapy in patients receiving free treatment from a government hospital in Blantyre, Malawi
    David J Bell
    Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi
    J Acquir Immune Defic Syndr 45:560-3. 2007
    ..To compare 3 measures of adherence to antiretroviral therapy (ART) in HIV-positive adults receiving free treatment from a public hospital in Malawi...
  10. pmc Evidence of improving antiretroviral therapy treatment delays: an analysis of eight years of programmatic outcomes in Blantyre, Malawi
    Derek J Sloan
    Malawi Liverpool Wellcome Trust and Liverpool School of Tropical Medicine, Chichiri 3, PO 30096, Blantyre, Malawi
    BMC Public Health 13:490. 2013
    ..However, the effects of rapid ART scale-up on delays between HIV diagnosis and treatment initiation have not been well described...
  11. ncbi request reprint Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000-2012
    Emma C Wall
    Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi
    Clin Infect Dis 58:e137-45. 2014
    ..We documented bacterial meningitis trends among adults and children presenting to a large teaching hospital in Malawi during introduction of Haemophilus influenzae type b (Hib) vaccination and the rollout of antiretroviral therapy (ART)...
  12. ncbi request reprint Incomplete Recovery of Pneumococcal CD4 T Cell Immunity after Initiation of Antiretroviral Therapy in HIV-Infected Malawian Adults
    Enoch Sepako
    Malawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi Respiratory Infection Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
    PLoS ONE 9:e100640. 2014
    ..Whether vaccination and prolonged ART can overcome this immunological defect and reduce the high levels of pneumococcal colonisation requires further evaluation. ..
  13. pmc Severe eye complications from Stevens-Johnson syndrome in a human immunodeficiency virus-infected patient in Malawi
    Markus Schulze Schwering
    Department of Ophthalmology, University of Malawi, Blantyre, Malawi
    Am J Trop Med Hyg 89:162-4. 2013
    ..We draw attention to preventive measures that can potentially reduce permanent ocular damage from SJS...
  14. pmc Development and validation of a global positioning system-based "map book" system for categorizing cluster residency status of community members living in high-density urban slums in Blantyre, Malawi
    Peter MacPherson
    Human Immunodeficiency Virus and Tuberculosis HIV TB Group, Malawi Liverpool Wellcome Trust Clinical Research Programme, P O Box 30096, Chichiri 3, Blantyre, Malawi
    Am J Epidemiol 177:1143-7. 2013
    ..90, 1.00). With map books, cluster residents were classified rapidly and accurately. If validated elsewhere, this approach could be of widespread value in that it would enable accurate categorization without home visits...
  15. pmc Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi
    Dean B Everett
    Malawi Liverpool Wellcome Trust Clinical Research Programme, College of Medicine, Chichiri, Blantyre, Malawi
    PLoS ONE 6:e17765. 2011
    ..To document trends in invasive pneumococcal disease (IPD) in a central hospital in Malawi during the period of national scale-up of antiretroviral therapy (ART) and cotrimoxazole prophylaxis...
  16. doi request reprint Cardiovascular risk factors in adult Malawians on long-term antiretroviral therapy
    William Muronya
    Department of Medicine, University of Malawi, College of Medicine, Private Bag 360, Blantyre 3, Malawi
    Trans R Soc Trop Med Hyg 105:644-9. 2011
    ..Cardiovascular risk factors were common among long-term ART patients in Malawi. This requires more attention and further study in programmes using the public health approach to ART...
  17. pmc Post exposure prophylaxis of HIV transmission after occupational injuries in Queen Elizabeth Central Hospital, Blantyre, Malawi, 2003 - 2008
    Gerrit C van der Maaten
    Department of Medicine, University of Malawi College of Medicine, Blantyre, Malawi
    Malawi Med J 22:15-9. 2010
    ..Measures to improve quality of the PEP programme include effective publicity campaigns, compulsory Hepatitis B vaccination and active tracing of HCWs who default follow up after PEP...
  18. pmc Determinants and consequences of failure of linkage to antiretroviral therapy at primary care level in Blantyre, Malawi: a prospective cohort study
    Peter MacPherson
    Clinical Group, Liverpool School of Tropical Medicine, Liverpool, Merseyside, United Kingdom
    PLoS ONE 7:e44794. 2012
    ..In the first study of this kind at primary care level, we investigated the pathway to care in the Malawian National Programme, one of the strongest in Africa...