E J van Hoogdalem
- Transdermal absorption of clindamycin and tretinoin from topically applied anti-acne formulations in manE J van Hoogdalem
Clinical Pharmacology Research Department, Yamanouchi Europe B V, Leiderdorp, The Netherlands
Biopharm Drug Dispos 19:563-9. 1998..There was no indications for a notable transdermal uptake of tretinoin during daily application of the gel in patients, nor for an enhancing effect of tretinoin on clindamycin uptake...
- Transdermal absorption of topical anti-acne agents in man; review of clinical pharmacokinetic dataE J van Hoogdalem
Clinical Pharmacology Research Department, Yamanouchi Europe B V, Leiderdorp, Netherlands
J Eur Acad Dermatol Venereol 11:S13-9; discussion S28-9. 1998..The fact that a topically applied compound may also become systemically available to a quantifiable extent, is not generally considered...
- Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteersE J van Hoogdalem
Yamanouchi Europe B V, Research Labs, Leiderdorp, Netherlands
Skin Pharmacol 9:104-10. 1996..The effect varied with body region. Zinc acetate thus provided to prolong the residence time of erythromycin on the skin...