S S Zoghbi

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates
    S S Zoghbi
    Departments of Diagnostic Radiology and Psychiatry, Yale University School of Medicine, P O Box 208042, 333 Cedar St, New Haven, CT 06520, USA
    Nucl Med Biol 28:91-6. 2001
  2. ncbi request reprint Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1134-40. 2000
  3. ncbi request reprint Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans
    M Fujita
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Eur J Pharmacol 368:161-72. 1999
  4. ncbi request reprint Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT
    C H van Dyck
    Department of Psychiatry, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Neurobiol Aging 21:497-501. 2000
  5. ncbi request reprint Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients
    A Anand
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Am J Psychiatry 157:1108-14. 2000
  6. ncbi request reprint [123I]IPCIT and [123I]beta-CIT as SPECT tracers for the dopamine transporter: a comparative analysis in nonhuman primates
    B E Scanley
    Yale University and VA Connecticut Healthcare Center, West Haven 06516, USA
    Nucl Med Biol 27:13-21. 2000
  7. ncbi request reprint Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans
    M Fujita
    Department of Psychiatry, Yale University, VA Connecticut, West Haven, CT 06516, USA
    Eur J Pharmacol 387:179-88. 2000
  8. ncbi request reprint Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors
    M Fujita
    Department of Psychiatry, Diagnostic Radiology, and Pharmacology, Yale University and VA Connecticut, West Haven, Connecticut 06516, USA
    Synapse 34:290-304. 1999
  9. ncbi request reprint Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS
    N P Verhoeff
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Epilepsia 40:1433-8. 1999
  10. ncbi request reprint Prediction of dopamine transporter binding availability by genotype: a preliminary report
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1700-3. 2000

Detail Information

Publications11

  1. ncbi request reprint Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates
    S S Zoghbi
    Departments of Diagnostic Radiology and Psychiatry, Yale University School of Medicine, P O Box 208042, 333 Cedar St, New Haven, CT 06520, USA
    Nucl Med Biol 28:91-6. 2001
    ....
  2. ncbi request reprint Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1134-40. 2000
    ..The authors tested for evidence of serotonergic dysfunction during acute abstinence from cocaine, a period of high risk for relapse in cocaine dependence...
  3. ncbi request reprint Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans
    M Fujita
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Eur J Pharmacol 368:161-72. 1999
    ..Clinical effects showed corresponding changes 1-2 weeks after the changes in the receptor. Thus, the decrease of benzodiazepine receptor densities may be one of the major mechanisms for tolerance development in humans...
  4. ncbi request reprint Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT
    C H van Dyck
    Department of Psychiatry, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Neurobiol Aging 21:497-501. 2000
    ..5% over the age range 18 to 88, or approximately 4.2% per decade. These results demonstrate reductions in the availability of central SERT binding sites with age in living human subjects...
  5. ncbi request reprint Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients
    A Anand
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Am J Psychiatry 157:1108-14. 2000
    ..In this study, dopamine receptor imaging combined with a pharmacological challenge of amphetamine was used to assess both pre- and postsynaptic aspects of dopamine neurotransmission in euthymic bipolar disorder patients...
  6. ncbi request reprint [123I]IPCIT and [123I]beta-CIT as SPECT tracers for the dopamine transporter: a comparative analysis in nonhuman primates
    B E Scanley
    Yale University and VA Connecticut Healthcare Center, West Haven 06516, USA
    Nucl Med Biol 27:13-21. 2000
    ..The peak equilibrium method is shown to overestimate striatal distribution volumes, primarily due to a difference in the calculated time of peak specific uptake...
  7. ncbi request reprint Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans
    M Fujita
    Department of Psychiatry, Yale University, VA Connecticut, West Haven, CT 06516, USA
    Eur J Pharmacol 387:179-88. 2000
    ..88, P=0.004). These results imply that [123I]epidepride, coupled with acute dopamine depletion might provide estimates of synaptic dopamine concentration...
  8. ncbi request reprint Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors
    M Fujita
    Department of Psychiatry, Diagnostic Radiology, and Pharmacology, Yale University and VA Connecticut, West Haven, Connecticut 06516, USA
    Synapse 34:290-304. 1999
    ..These results suggest that correct V'(3) values can be obtained with the one input function model both in high- and low-density regions...
  9. ncbi request reprint Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS
    N P Verhoeff
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Epilepsia 40:1433-8. 1999
    ....
  10. ncbi request reprint Prediction of dopamine transporter binding availability by genotype: a preliminary report
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1700-3. 2000
    ..Evidence of a relationship between genotype and binding availability was assessed for the dopamine and serotonin transporter genes...
  11. ncbi request reprint Reproducibility of in vivo brain measures of 5-HT2A receptors with PET and
    J C Soares
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Psychiatry Res 106:81-93. 2001
    ....