S S Zoghbi

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates
    S S Zoghbi
    Departments of Diagnostic Radiology and Psychiatry, Yale University School of Medicine, P O Box 208042, 333 Cedar St, New Haven, CT 06520, USA
    Nucl Med Biol 28:91-6. 2001
  2. ncbi Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1134-40. 2000
  3. ncbi Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans
    M Fujita
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Eur J Pharmacol 368:161-72. 1999
  4. ncbi Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT
    C H van Dyck
    Department of Psychiatry, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Neurobiol Aging 21:497-501. 2000
  5. ncbi Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients
    A Anand
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Am J Psychiatry 157:1108-14. 2000
  6. ncbi [123I]IPCIT and [123I]beta-CIT as SPECT tracers for the dopamine transporter: a comparative analysis in nonhuman primates
    B E Scanley
    Yale University and VA Connecticut Healthcare Center, West Haven 06516, USA
    Nucl Med Biol 27:13-21. 2000
  7. ncbi Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans
    M Fujita
    Department of Psychiatry, Yale University, VA Connecticut, West Haven, CT 06516, USA
    Eur J Pharmacol 387:179-88. 2000
  8. ncbi Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors
    M Fujita
    Department of Psychiatry, Diagnostic Radiology, and Pharmacology, Yale University and VA Connecticut, West Haven, Connecticut 06516, USA
    Synapse 34:290-304. 1999
  9. ncbi Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS
    N P Verhoeff
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Epilepsia 40:1433-8. 1999
  10. ncbi Prediction of dopamine transporter binding availability by genotype: a preliminary report
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1700-3. 2000

Detail Information

Publications11

  1. ncbi Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates
    S S Zoghbi
    Departments of Diagnostic Radiology and Psychiatry, Yale University School of Medicine, P O Box 208042, 333 Cedar St, New Haven, CT 06520, USA
    Nucl Med Biol 28:91-6. 2001
    ....
  2. ncbi Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1134-40. 2000
    ..The authors tested for evidence of serotonergic dysfunction during acute abstinence from cocaine, a period of high risk for relapse in cocaine dependence...
  3. ncbi Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans
    M Fujita
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Eur J Pharmacol 368:161-72. 1999
    ..Clinical effects showed corresponding changes 1-2 weeks after the changes in the receptor. Thus, the decrease of benzodiazepine receptor densities may be one of the major mechanisms for tolerance development in humans...
  4. ncbi Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT
    C H van Dyck
    Department of Psychiatry, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Neurobiol Aging 21:497-501. 2000
    ..5% over the age range 18 to 88, or approximately 4.2% per decade. These results demonstrate reductions in the availability of central SERT binding sites with age in living human subjects...
  5. ncbi Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients
    A Anand
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Am J Psychiatry 157:1108-14. 2000
    ..In this study, dopamine receptor imaging combined with a pharmacological challenge of amphetamine was used to assess both pre- and postsynaptic aspects of dopamine neurotransmission in euthymic bipolar disorder patients...
  6. ncbi [123I]IPCIT and [123I]beta-CIT as SPECT tracers for the dopamine transporter: a comparative analysis in nonhuman primates
    B E Scanley
    Yale University and VA Connecticut Healthcare Center, West Haven 06516, USA
    Nucl Med Biol 27:13-21. 2000
    ..The peak equilibrium method is shown to overestimate striatal distribution volumes, primarily due to a difference in the calculated time of peak specific uptake...
  7. ncbi Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans
    M Fujita
    Department of Psychiatry, Yale University, VA Connecticut, West Haven, CT 06516, USA
    Eur J Pharmacol 387:179-88. 2000
    ..88, P=0.004). These results imply that [123I]epidepride, coupled with acute dopamine depletion might provide estimates of synaptic dopamine concentration...
  8. ncbi Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors
    M Fujita
    Department of Psychiatry, Diagnostic Radiology, and Pharmacology, Yale University and VA Connecticut, West Haven, Connecticut 06516, USA
    Synapse 34:290-304. 1999
    ..These results suggest that correct V'(3) values can be obtained with the one input function model both in high- and low-density regions...
  9. ncbi Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS
    N P Verhoeff
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Epilepsia 40:1433-8. 1999
    ....
  10. ncbi Prediction of dopamine transporter binding availability by genotype: a preliminary report
    L K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Psychiatry 157:1700-3. 2000
    ..Evidence of a relationship between genotype and binding availability was assessed for the dopamine and serotonin transporter genes...
  11. ncbi Reproducibility of in vivo brain measures of 5-HT2A receptors with PET and
    J C Soares
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Psychiatry Res 106:81-93. 2001
    ....