Yawei Zhang

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Relationship of folate, vitamin B12 and methylation of insulin-like growth factor-II in maternal and cord blood
    Y Ba
    School of Public Health, Zhengzhou University, Zhengzhou, China
    Eur J Clin Nutr 65:480-5. 2011
  2. pmc Changing patterns of bladder cancer in the USA: evidence of heterogeneous disease
    Yawei Zhang
    School of Public Health, Yale University, New Haven, CT 06520, USA
    BJU Int 109:52-6. 2012
  3. pmc Modeled nitrate levels in well water supplies and prevalence of abnormal thyroid conditions among the Old Order Amish in Pennsylvania
    Briseis Aschebrook-Kilfoy
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Environ Health 11:6. 2012
  4. ncbi request reprint Hair dye use and risk of human cancer
    Yawei Zhang
    Yale University School of Public Health, New Haven, CT 06520, USA
    Front Biosci (Elite Ed) 4:516-28. 2012
  5. pmc A novel COMP mutation in a pseudoachondroplasia family of Chinese origin
    Li Dai
    National Center for Birth Defects Monitoring, West China Second University Hospital, Sichuan University, 20 Ren Min Nan Lu Section 3, Chengdu 610041, China
    BMC Med Genet 12:72. 2011
  6. pmc Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis
    Yu Tong
    Open laboratory, West China Second University Hospital, Sichuan University, Chengdu, PR China
    BMC Med Genet 10:15. 2009
  7. ncbi request reprint Family history of hematopoietic and non-hematopoietic malignancies and risk of non-Hodgkin lymphoma
    Yawei Zhang
    Yale University School of Epidemiology and Public Health, 60 College Street, LEPH 440, New Haven, CT 06520, USA
    Cancer Causes Control 18:351-9. 2007
  8. ncbi request reprint Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma
    Yawei Zhang
    Yale University School of Epidemiology and Public Health, New Haven, CT 06520 8034, USA
    Am J Epidemiol 165:1255-64. 2007
  9. ncbi request reprint Family history of cancer and risk of lung cancer among nonsmoking Chinese women
    Yawei Zhang
    School of Epidemiology and Public Health, Yale University, 60 College Street, LEPH 440, New Haven, CT 06520, USA
    Cancer Epidemiol Biomarkers Prev 16:2432-5. 2007
  10. ncbi request reprint A putative exonic splicing polymorphism in the BCL6 gene and the risk of non-Hodgkin lymphoma
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    J Natl Cancer Inst 97:1616-8. 2005

Research Grants

Detail Information

Publications98

  1. pmc Relationship of folate, vitamin B12 and methylation of insulin-like growth factor-II in maternal and cord blood
    Y Ba
    School of Public Health, Zhengzhou University, Zhengzhou, China
    Eur J Clin Nutr 65:480-5. 2011
    ..The aim of the study is to investigate the relationship between folate, vitamin B(12) and methylation of the IGF2 gene in maternal and cord blood...
  2. pmc Changing patterns of bladder cancer in the USA: evidence of heterogeneous disease
    Yawei Zhang
    School of Public Health, Yale University, New Haven, CT 06520, USA
    BJU Int 109:52-6. 2012
    ..To test the hypothesis that bladder cancer is a heterogeneous disease...
  3. pmc Modeled nitrate levels in well water supplies and prevalence of abnormal thyroid conditions among the Old Order Amish in Pennsylvania
    Briseis Aschebrook-Kilfoy
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Environ Health 11:6. 2012
    ..Nitrate intake from drinking water and dietary sources can interfere with the uptake of iodide by the thyroid, thus potentially impacting thyroid function...
  4. ncbi request reprint Hair dye use and risk of human cancer
    Yawei Zhang
    Yale University School of Public Health, New Haven, CT 06520, USA
    Front Biosci (Elite Ed) 4:516-28. 2012
    ..Several methodological issues should also be considered in future studies including completed hair dye use information such as on timing, duration, frequency and type of hair dye product use...
  5. pmc A novel COMP mutation in a pseudoachondroplasia family of Chinese origin
    Li Dai
    National Center for Birth Defects Monitoring, West China Second University Hospital, Sichuan University, 20 Ren Min Nan Lu Section 3, Chengdu 610041, China
    BMC Med Genet 12:72. 2011
    ..Pseudoachondroplasia (PSACH) is caused exclusively by mutations in the gene for cartilage oligomeric matrix protein (COMP). Only a small number of studies have documented the clinical phenotype and genetic basis in Chinese PSACH patients...
  6. pmc Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis
    Yu Tong
    Open laboratory, West China Second University Hospital, Sichuan University, Chengdu, PR China
    BMC Med Genet 10:15. 2009
    ....
  7. ncbi request reprint Family history of hematopoietic and non-hematopoietic malignancies and risk of non-Hodgkin lymphoma
    Yawei Zhang
    Yale University School of Epidemiology and Public Health, 60 College Street, LEPH 440, New Haven, CT 06520, USA
    Cancer Causes Control 18:351-9. 2007
    ..The relationship between family history of specific hematopoietic and non-hematopoietic malignancies and the risk of NHL and by NHL subtypes are unclear...
  8. ncbi request reprint Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma
    Yawei Zhang
    Yale University School of Epidemiology and Public Health, New Haven, CT 06520 8034, USA
    Am J Epidemiol 165:1255-64. 2007
    ..0051). The risk appears to vary by non-Hodgkin's lymphoma subtypes. Further investigations of the role of ultraviolet radiation on the risk of non-Hodgkin's lymphoma are warranted...
  9. ncbi request reprint Family history of cancer and risk of lung cancer among nonsmoking Chinese women
    Yawei Zhang
    School of Epidemiology and Public Health, Yale University, 60 College Street, LEPH 440, New Haven, CT 06520, USA
    Cancer Epidemiol Biomarkers Prev 16:2432-5. 2007
    ..The associations were stronger when a sibling, rather than a parent, was affected. The apparent link between lung cancer risk and a family history of colorectal, stomach, and pancreas cancers may be worth further investigation...
  10. ncbi request reprint A putative exonic splicing polymorphism in the BCL6 gene and the risk of non-Hodgkin lymphoma
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    J Natl Cancer Inst 97:1616-8. 2005
    ..2, 95% CI = 2.0 to 13.3). Our results support the hypothesis that a genetic variant that could alter mRNA transcripts of BCL6 may contribute to the etiology of NHL and suggest that this variant warrants further investigation...
  11. pmc Genetic variations in xenobiotic metabolic pathway genes, personal hair dye use, and risk of non-Hodgkin lymphoma
    Yawei Zhang
    School of Public Health, Yale University, New Haven, Connecticut 06520 8034, USA
    Am J Epidemiol 170:1222-30. 2009
    ..A possible role of genetic variation in xenobiotic metabolism in the carcinogenicity of hair dye use needs to be confirmed in larger studies...
  12. ncbi request reprint Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer
    Yawei Zhang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:353-8. 2006
    ..6; 95% CI, 1.1-2.4; P = 0.02). In conclusion, our results do not support that the polymorphisms evaluated in six BER pathway genes play a major role in breast carcinogenesis, particularly in Caucasian populations...
  13. pmc Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma
    Xuesong Han
    Yale University School of Public Health, New Haven, CT 06520 8034, USA
    Cancer Epidemiol Biomarkers Prev 18:1429-38. 2009
    ..Our results suggest that genetic polymorphisms in oxidative stress pathway genes, especially in the NOS genes, modify the association between vegetable and fruit intake and risk of NHL...
  14. pmc Genetic polymorphisms in the metabolic pathway and non-Hodgkin lymphoma survival
    Xuesong Han
    Yale University School of Public Health, 60 College Street, New Haven, CT 06520 8034, USA
    Am J Hematol 85:51-6. 2010
    ..Our study suggests that genetic polymorphisms in metabolic pathways may help improve the prediction of NHL survival and prognosis...
  15. pmc Genetic polymorphisms in glutathione S-transferases and cytochrome P450s, tobacco smoking, and risk of non-Hodgkin lymphoma
    Briseis A Kilfoy
    Department of Environmental Health Sciences, School of Epidemiology and Public Health, Yale University, New Haven, Connecticut 06520 8034, USA
    Am J Hematol 84:279-82. 2009
    ..4; 95% CI 1.0-5.7), but a decreased risk for the variant G allele for CYP1B1 (OR = 0.6, 95% CI 0.4-1.0). Our results confer support investigation of the gene-environment interaction in a larger study population of DLBCL...
  16. ncbi request reprint Cigarette smoking, glutathione-s-transferase M1 and t1 genetic polymorphisms, and breast cancer risk (United States)
    Tongzhang Zheng
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06510, USA
    Cancer Causes Control 13:637-45. 2002
    ..We sought to determine if there is a gene-environment interaction between GSTM I (GSTM1A and GSTM1B), and GSTT1 genotypes and cigarette smoking in the risk of breast cancer...
  17. ncbi request reprint Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma
    Qing Lan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, EPS 8109, Bethesda, MD 20892 7240, USA
    Hum Genet 121:161-8. 2007
    ..013), but was also associated with non-significant increased risks for each of the common B-cell histologies. These results suggest that SNPs in genes related to the oxidative stress pathway may be associated with increased risk of NHL...
  18. pmc Occupational exposure to solvents and risk of non-Hodgkin lymphoma in Connecticut women
    Rong Wang
    Division of Environmental Health Sciences, Yale University School of Public Health, New Haven, Connecticut 06520 8034, USA
    Am J Epidemiol 169:176-85. 2009
    ..Results suggest an increased risk of NHL associated with occupational exposure to organic solvents for women...
  19. ncbi request reprint Genotype frequency and F ST analysis of polymorphisms in immunoregulatory genes in Chinese and Caucasian populations
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Immunogenetics 59:839-52. 2007
    ..25). These results suggest that there is substantial genetic diversity in immune genes and exploration of SNP associations with immune-related diseases that vary in incidence across these two populations may be warranted...
  20. pmc Family history of malignancies and risk of breast cancer: prospective data from the Shanghai women's health study
    Briseis A Kilfoy
    School of Epidemiology and Public Health, Yale University, New Haven, CT 06520 8034, USA
    Cancer Causes Control 19:1139-45. 2008
    ..The link between breast cancer risk and family history of cancers of the lung and esophagus, as well as leukemia, warrants further investigation...
  21. ncbi request reprint Menstrual and reproductive factors and risk of non-Hodgkin's lymphoma among Connecticut women
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT, USA
    Am J Epidemiol 160:766-73. 2004
    ..These findings support a reduced risk of non-Hodgkin's lymphoma associated with multiple pregnancies and an increased risk of non-Hodgkin's lymphoma associated with later age at menarche...
  22. pmc Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut
    Kyoung Mu Lee
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Am J Hematol 85:560-3. 2010
    ..Additional studies are needed to replicate these findings and, more generally, to explore the manner in which genes and receptors may influence the pathogenesis of this poorly understood malignancy...
  23. pmc Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma
    Briseis A Kilfoy
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Cancer Causes Control 21:127-33. 2010
    ..We conclude that these findings require replication in larger studies and ultimately in pooled analyses...
  24. pmc Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development
    Lindsay M Morton
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 18:1259-70. 2009
    ..Replication of our findings and further study to identify functional SNPs are warranted...
  25. pmc Genetic variation in metabolic genes, occupational solvent exposure, and risk of non-hodgkin lymphoma
    Kathryn Hughes Barry
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Am J Epidemiol 173:404-13. 2011
    ..77, 95% CI: 1.06, 2.97; P(interaction) = 0.06). In contrast, no effect was observed among AG/GG women. Additional studies with larger sample size are needed to replicate these findings...
  26. pmc Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies
    Min Shen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Br J Haematol 151:239-44. 2010
    ..These results support the hypothesis that common genetic polymorphisms in human DNA repair genes may modify the risk of NHL...
  27. doi request reprint COL1A2 gene polymorphisms (Pvu II and Rsa I), serum calciotropic hormone levels, and dental fluorosis
    Hui Huang
    Department of Environmental Health, Zhengzhou University School of Public Health, Zhengzhou, China
    Community Dent Oral Epidemiol 36:517-22. 2008
    ..To investigate the relationship between dental fluorosis, polymorphisms in the COL1A2 gene, and serum calciotropic hormone levels...
  28. pmc Polymorphisms in immune function genes and non-Hodgkin lymphoma survival
    Briseis Aschebrook-Kilfoy
    School of Public Health, Yale University, New Haven, CT, USA
    J Cancer Surviv 6:102-14. 2012
    ..Given these biologic properties, there is reason to hypothesize that cytokine activity influences the pathogenesis of non-Hodgkin lymphoma (NHL)...
  29. pmc Caspase polymorphisms and genetic susceptibility to multiple myeloma
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
    Hematol Oncol 26:148-51. 2008
    ..The protective associations observed in two key caspase genes suggest that genetic variation in CASP genes may play an important role in the aetiology of multiple myeloma...
  30. pmc A birth cohort analysis of the incidence of papillary thyroid cancer in the United States, 1973-2004
    Cairong Zhu
    Yale University School of Public Health, New Haven, Connecticut 06520, USA
    Thyroid 19:1061-6. 2009
    ....
  31. pmc Clock-cancer connection in non-Hodgkin's lymphoma: a genetic association study and pathway analysis of the circadian gene cryptochrome 2
    Aaron E Hoffman
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer Res 69:3605-13. 2009
    ..75E(-9)) and hematologic disease (B-H P = 8.01E(-8)). In conclusion, both genetic association and functional analyses suggest that the circadian gene CRY2 may play an important role in NHL development...
  32. ncbi request reprint Blood transfusion and risk of non-Hodgkin's lymphoma in Connecticut women
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT, USA
    Am J Epidemiol 160:325-30. 2004
    ..In summary, the authors' findings do not support the hypothesis that allogeneic blood transfusion increases the risk of non-Hodgkin's lymphoma...
  33. pmc The core circadian gene Cryptochrome 2 influences breast cancer risk, possibly by mediating hormone signaling
    Aaron E Hoffman
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Cancer Prev Res (Phila) 3:539-48. 2010
    ..These findings suggest a role for CRY2 in breast tumorigenesis and provide further evidence that the circadian system may be an important modulator of hormone-related cancer susceptibility...
  34. pmc Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) polymorphisms and risk of non-Hodgkin lymphoma in the InterLymph Consortium
    Christine F Skibola
    237A Hildebrand Hall, School of Public Health, University of California, Berkeley, Berkeley, CA 94720 7360, USA
    Am J Epidemiol 171:267-76. 2010
    ..04). These findings strengthen previous results for DLBCL and the LTA 252A>G/TNF -308A locus and provide robust evidence that these TNF/LTA gene variants, or others in linkage disequilibrium, are involved in NHL etiology...
  35. doi request reprint Lymphoma survival patterns by WHO subtype in the United States, 1973-2003
    Xuesong Han
    Yale University School of Epidemiology and Public Health, 60 College Street, LEPH 440, P O Box 208034, New Haven, CT 06520 8034, USA
    Cancer Causes Control 19:841-58. 2008
    ..The differences in lymphoma survival patterns suggest that distinct prognostic risk factors impact survival by subtype and that future research and public health interventions should address racial disparities in lymphoma survivorship...
  36. pmc Vegetable and fruit intake and non-Hodgkin lymphoma survival in Connecticut women
    Xuesong Han
    School of Public Health, Yale University, New Haven, CT, USA
    Leuk Lymphoma 51:1047-54. 2010
    ..Our study suggests that increasing vegetable and citrus fruit consumption could be a useful strategy to improve survival in NHL patients...
  37. pmc Genetic variation in Th1/Th2 pathway genes and risk of non-Hodgkin lymphoma: a pooled analysis of three population-based case-control studies
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Br J Haematol 153:341-50. 2011
    ..This SNP was also associated specifically with risk of follicular lymphoma (allele risk OR= 1·26; P(trend)= 0·0012). These findings suggest that genetic variation in Th1/Th2 cytokine genes may contribute to lymphomagenesis...
  38. ncbi request reprint Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma
    Qing Lan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, DHHS, Bethesda, MD 20892 7240, USA
    Carcinogenesis 28:823-7. 2007
    ..The striking protective associations observed for polymorphisms in all four genes for NHL and/or one or more subtypes suggest that genetic variation in CASP genes may play an important role in the etiology of NHL...
  39. ncbi request reprint Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma among women in Connecticut
    Min Shen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    Hum Genet 119:659-68. 2006
    ..Further work is needed to extend these findings by carrying out extended haplotype analyses of these and related genes and to replicate the observations in other studies...
  40. pmc Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma
    Qing Lan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, MSC 7240, 6120 Executive Blvd, EPS 8109, Bethesda, MD 20892 7240, USA
    Blood 107:4101-8. 2006
    ..84; 95% CI = 1.79-8.22; P < .001). Further, the IL10 and IL4 SNP associations remained significant after adjusting for multiple comparisons. These results suggest that SNPs in Th2 cytokine genes may be associated with risk of NHL...
  41. pmc Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
    PLoS ONE 4:e5360. 2009
    ..We hypothesized that the TNF and NF-kappaB pathways are important for NHL and that gene variations across the pathways may alter NHL risk...
  42. pmc Identification of non-Hodgkin's lymphoma prognosis signatures using the CTGDR method
    Shuangge Ma
    School of Public Health, Yale University, New Haven, CT 06510, USA
    Bioinformatics 26:15-21. 2010
    ..Biomedical studies have shown that genomic variations, measured with SNPs (single nucleotide polymorphisms) in genes, may have independent predictive power for disease-free survival in NHL patients beyond clinical measurements...
  43. ncbi request reprint Common variants in genes that mediate immunity and risk of multiple myeloma
    Elizabeth E Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Int J Cancer 120:2715-22. 2007
    ..Our findings provide preliminary evidence that common genetic variants in specific immune-mediated pathways could influence the risk of MM...
  44. ncbi request reprint Prior medical conditions and medication use and risk of non-Hodgkin lymphoma in Connecticut United States women
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Cancer Causes Control 15:419-28. 2004
    ..To further investigate the role of prior medical conditions and medication use in the etiology of non-Hodgkin lymphoma (NHL), we analyzed the data from a population-based case-control study of NHL in Connecticut women...
  45. pmc A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Carcinogenesis 30:275-81. 2009
    ..No associations with TLR4 variants were observed. This pooled analysis provides strong evidence that variation in the TLR10-TLR1-TLR6 region is associated with NHL risk and suggests that TLR2 variants may influence susceptibility to MZL...
  46. ncbi request reprint Serum polychlorinated biphenyls, cytochrome P-450 1A1 polymorphisms, and risk of breast cancer in Connecticut women
    Yawei Zhang
    Department of Epidemiology and Public Health, School of Medicine, Yale University, New Haven, CT 06510, USA
    Am J Epidemiol 160:1177-83. 2004
    ..In summary, the CYP1A1 m2 genetic polymorphism was associated with increased risk of female breast cancer and may modify the relation between PCB exposure and breast cancer risk...
  47. pmc CLOCK in breast tumorigenesis: genetic, epigenetic, and transcriptional profiling analyses
    Aaron E Hoffman
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer Res 70:1459-68. 2010
    ..Our findings support the hypothesis that circadian genes influence tumorigenesis, and identify a set of circadian gene variants as candidate breast cancer susceptibility biomarkers...
  48. pmc Occupational solvent exposure, genetic variation of DNA repair genes, and the risk of non-Hodgkin's lymphoma
    Jie Jiao
    Henan Provincial Institute of Occupational Health, Zhengzhou, China
    Eur J Cancer Prev 21:580-4. 2012
    ..0042). Our study results suggest that genetic variations in DNA repair genes modify the association between occupational exposure to solvents and the risk of NHL...
  49. doi request reprint Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma
    Wei Hu
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892 7240, USA
    Environ Mol Mutagen 54:72-7. 2013
    ..39, P-trend = 0.033). Our results suggest that genetic variation in pattern-recognition genes is associated with the risk of NHL or specific NHL subtypes, but these preliminary findings require replication in larger studies...
  50. pmc Genetic polymorphisms in oxidative stress pathway genes and modification of BMI and risk of non-Hodgkin lymphoma
    Christopher Kim
    Yale University School of Public Health, New Haven, CT 06520, USA
    Cancer Epidemiol Biomarkers Prev 21:866-8. 2012
    ....
  51. pmc Non-synonymous polymorphisms in the circadian gene NPAS2 and breast cancer risk
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, LEPH Room 702, New Haven, CT 06520, USA
    Breast Cancer Res Treat 107:421-5. 2008
    ..46-0.81, P = 0.001). This is the first evidence demonstrating a role of the circadian gene NPAS2 in human breast cancer, suggesting that genetic variations in circadian genes might be a novel panel of biomarkers for breast cancer risk...
  52. pmc Alcohol consumption and non-Hodgkin lymphoma survival
    Xuesong Han
    School of Public Health, Yale University, New Haven, CT 06520, USA
    J Cancer Surviv 4:101-9. 2010
    ..Alcohol drinking has also been associated with reduced risk of non-Hodgkin lymphoma (NHL). Here, we examined the role of alcohol consumption on NHL survival by type of alcohol consumed and NHL subtype...
  53. ncbi request reprint Hair-coloring product use and risk of non-Hodgkin's lymphoma: a population-based case-control study in Connecticut
    Yawei Zhang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06510, USA
    Am J Epidemiol 159:148-54. 2004
    ..Further studies are warranted to show whether the observed association reflects the change in hair dye formula contents during the past two decades or indicates that recent users are still in their induction and latent periods...
  54. ncbi request reprint Hepatitis C virus and risk of non-Hodgkin lymphoma: a population-based case-control study among Connecticut women
    Lindsay McOmber Morton
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Cancer Epidemiol Biomarkers Prev 13:425-30. 2004
    ..To further investigate the link between HCV and NHL, we conducted HCV testing on serum samples of 998 women (464 cases; 534 controls) from a population-based case-control study of women in Connecticut...
  55. pmc Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Blood 114:264-7. 2009
    ..It is noteworthy that genetic variants in CASP8 were associated with risk of all major NHL subtypes. Our findings suggest that genetic variation in caspases may play an important role in lymphomagenesis...
  56. ncbi request reprint Occupation and risk of pancreatic cancer: a population-based case-control study in iowa
    Yawei Zhang
    Yale University School of Public Health, New Haven, Connecticut 06520, USA
    J Occup Environ Med 47:392-8. 2005
    ..Previous epidemiological studies have inconsistently linked various occupations and industries to pancreatic cancer risk...
  57. pmc Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Int J Cancer 120:432-5. 2007
    ....
  58. pmc Role of one-carbon metabolizing pathway genes and gene-nutrient interaction in the risk of non-Hodgkin lymphoma
    Qian Li
    Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, 06510, USA
    Cancer Causes Control 24:1875-84. 2013
    ..However, the results have been inconsistent. The objectives of this study were to examine the potential relationship between gene-nutrient interactions and the risk of non-Hodgkin lymphoma (NHL)...
  59. ncbi request reprint Nutrients contributing to one-carbon metabolism and risk of non-Hodgkin lymphoma subtypes
    Stella Koutros
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 20852, USA
    Am J Epidemiol 167:287-94. 2008
    ..lowest: OR = 0.23, 95% CI: 0.08, 0.65; p-trend = 0.002). These findings suggest that these nutrients may be important for susceptibility to NHL...
  60. pmc The risk of second cancers after diagnosis of primary thyroid cancer is elevated in thyroid microcarcinomas
    Christopher Kim
    1 Yale School of Public Health, Yale University, New Haven, CT 06520, USA
    Thyroid 23:575-82. 2013
    ..This study examined the risk of second cancers after development of a thyroid cancer, primary utilizing the Surveillance, Epidemiology, and End Results (SEER) program database...
  61. ncbi request reprint Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States)
    Lindsay McOmber Morton
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer Causes Control 14:687-94. 2003
    ..Data from a population-based case-control study among women in Connecticut were analyzed to determine the potential impact of alcohol consumption on risk of NHL...
  62. pmc International patterns and trends in thyroid cancer incidence, 1973-2002
    Briseis A Kilfoy
    Yale School of Public Health, Yale University, 60 College Street, LEPH 440, P O Box 208034, New Haven, CT 06520, USA
    Cancer Causes Control 20:525-31. 2009
    ....
  63. ncbi request reprint Diet and nutrient intakes and risk of non-Hodgkin's lymphoma in Connecticut women
    Tongzhang Zheng
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Am J Epidemiol 159:454-66. 2004
    ..The antioxidant or inhibiting nitrosation reaction properties of vegetables and fruits may result in a reduced risk. Further investigation of the role of dietary intakes on the risk of NHL is warranted...
  64. pmc Risk of non-Hodgkin lymphoma and nitrate and nitrite from the diet in Connecticut women
    Briseis A Kilfoy
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, EPS, Room 8111, 6120 Executive Boulevard, Rockville, MD, 20852 7244, USA
    Cancer Causes Control 21:889-96. 2010
    ..We conclude that these results should be replicated in a larger study with data on drinking water as well as dietary sources of nitrate intake...
  65. pmc Genetic variation in cell cycle and apoptosis related genes and multiple myeloma risk
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, United States
    Leuk Res 33:1609-14. 2009
    ..005). Haplotype analyses supported the SNP findings. These findings suggest that genetic variation in cell cycle and apoptosis genes may play a key role in multiple myeloma and warrant further investigation through replication studies...
  66. pmc Personal use of hair dye and the risk of certain subtypes of non-Hodgkin lymphoma
    Yawei Zhang
    Environmental Science Division, School of Public Health, Yale University, New Haven, CT, USA
    Am J Epidemiol 167:1321-31. 2008
    ..1, 2.0). These results indicate that personal hair-dye use may play a role in risks of FL and CLL/SLL in women who started use before 1980 and that increased risk of FL among women who started use during or after 1980 cannot be excluded...
  67. pmc Quality of life among testicular cancer survivors: a case-control study in the United States
    Christopher Kim
    Yale School of Public Health, Yale University, 60 College Street, LEPH 440, New Haven, CT 06520, USA
    Qual Life Res 20:1629-37. 2011
    ..Evidence from previous studies has suggested there may be physical and mental changes in health among testicular cancer survivors. No studies have been conducted in the United States, however...
  68. pmc Fertility among testicular cancer survivors: a case-control study in the U.S
    Christopher Kim
    Yale University, New Haven, CT 06520, USA
    J Cancer Surviv 4:266-73. 2010
    ..Although TGCT treatment directly affects gonadal tissues, it remains unclear whether there are long-term effects on fertility...
  69. pmc Genotypes and haplotypes of the methyl-CpG-binding domain 2 modify breast cancer risk dependent upon menopausal status
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    Breast Cancer Res 7:R745-52. 2005
    ..MBD2 may also mediate gene activation because of its potential DNA demethylase activity. The present case-control study investigated associations between two single nucleotide polymorphisms (SNPs) in the MBD2 gene and breast cancer risk...
  70. ncbi request reprint Occupational and leisure-time physical activity and risk of colon cancer by subsite
    Yawei Zhang
    Yale University School of Public Health, New Haven, Connecticut, USA
    J Occup Environ Med 48:236-43. 2006
    ..Studies of physical activity and colon cancer risk by anatomic site have provided inconsistent results...
  71. pmc A pooled analysis of three studies evaluating genetic variation in innate immunity genes and non-Hodgkin lymphoma risk
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
    Br J Haematol 152:721-6. 2011
    ....
  72. pmc Variation in innate immunity genes and risk of multiple myeloma
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD, USA
    Hematol Oncol 29:42-6. 2011
    ..0 × 10(-5) , P(permutation)  = 0.07). Our findings suggest that genetic variants in SERPINE1 and HGF, and possibly CCR7, are associated with MM risk, and warrant further investigation in other studies...
  73. pmc Sexual functioning among testicular cancer survivors: a case-control study in the U.S
    Christopher Kim
    Yale School of Public Health, Yale University, 60 College Street, New Haven, CT 06520, USA
    J Psychosom Res 73:68-73. 2012
    ..We conducted a case-control study among United States military men to examine whether testicular cancer survivors experienced impaired sexual function...
  74. pmc Polymorphisms in complement system genes and risk of non-Hodgkin lymphoma
    Bryan A Bassig
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892 7240, USA
    Environ Mol Mutagen 53:145-51. 2012
    ..Our results suggest a potential role of the complement system in susceptibility to NHL; however, our results should be viewed as exploratory and further replication is needed to clarify these preliminary findings...
  75. ncbi request reprint A population-based case-control study of occupation and renal cell carcinoma risk in Iowa
    Yawei Zhang
    Yale University School of Public Health, New Haven, Connecticut, USA
    J Occup Environ Med 46:235-40. 2004
    ..1-11.3); colleges and universities (OR 7.6-95% CI = 2.3-25.6); and retail, including those in grocery stores (OR 2.2, 95% CI = 1.0-4.7). Our results indicate that occupational exposures may increase the risk of renal cell carcinoma...
  76. pmc Polymorphisms in integrin genes and lymphoma risk
    Min Shen
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7240, USA
    Leuk Res 35:968-70. 2011
    ..01 level. While our results suggest that genetic polymorphisms in integrin genes may play a role in the genesis of lymphoma in women, they should be viewed as exploratory until they are replicated in additional populations...
  77. ncbi request reprint Maternal smoking and testicular germ cell tumors
    Katherine A McGlynn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD, USA
    Cancer Epidemiol Biomarkers Prev 15:1820-4. 2006
    ..Other early life exposures, however, may explain the familial clustering of lung cancer in mothers and TGCT in sons...
  78. pmc Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, United States
    Mutat Res 639:80-8. 2008
    ..Our findings suggest that bioinformatic tools are useful in predicting SNP functionality and may facilitate future genetic epidemiological studies...
  79. ncbi request reprint Occupation and risk of non-Hodgkin's lymphoma and chronic lymphocytic leukemia
    Tongzhang Zheng
    Division of Environmental Health Science, Yale University School of Public Health, New Haven, CT, USA
    J Occup Environ Med 44:469-74. 2002
    ..These data suggest that the workers employed in these industries or occupations experienced an increased risk of NHL and CLL, and the risks associated with these industries or occupations may vary by histological type of NHL...
  80. pmc Does "clock" matter in prostate cancer?
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Cancer Epidemiol Biomarkers Prev 15:3-5. 2006
    ..Confirmation of this hypothesis will add to our understanding of the role of the circadian clock in prostate tumorigenesis and further facilitate the development of novel risk and prognostic biomarkers for prostate cancer...
  81. ncbi request reprint Occupation and bladder cancer: a population-based, case-control study in Iowa
    Tongzhang Zheng
    Division of Environmental Health Science, Yale University School of Public Health, New Haven, Connecticut, USA
    J Occup Environ Med 44:685-91. 2002
    ..Housekeepers and butlers and workers in laundering and dry cleaning were also at increased risk. In conclusion, these results suggest that occupational exposures may play a significant role in the risk of bladder cancer...
  82. ncbi request reprint Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium
    Nathaniel Rothman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Lancet Oncol 7:27-38. 2006
    ..We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph)...
  83. ncbi request reprint Period3 structural variation: a circadian biomarker associated with breast cancer in young women
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Cancer Epidemiol Biomarkers Prev 14:268-70. 2005
    ..7; 95% confidence interval, 1.0-3.0). Our finding suggests that the circadian genes might be a novel panel of potential biomarkers for breast cancer and worth further investigation...
  84. ncbi request reprint Childhood asthma in Beijing, China: a population-based case-control study
    Tongzhang Zheng
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06510, USA
    Am J Epidemiol 156:977-83. 2002
    ..8, 95% CI: 1.0, 3.2). An increased risk was also found for those having both a dog and a cat as pets (OR = 1.5, 95% CI: 1.0, 2.3) or for finding both cockroaches and rats inside their houses (OR = 1.8, 95% CI: 1.2, 2.8)...
  85. ncbi request reprint Risk of multiple myeloma following medication use and medical conditions: a case-control study in Connecticut women
    Ola Landgren
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Building EPS Room 7110, Bethesda, MD 20892 7236, USA
    Cancer Epidemiol Biomarkers Prev 15:2342-7. 2006
    ..We conducted a population-based case-control study to investigate the role of medical history in the etiology of multiple myeloma among Connecticut women...
  86. ncbi request reprint Through the looking glass at early-life exposures and breast cancer risk
    Michele R Forman
    Laboratory of Biosystems and Cancer, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Invest 23:609-24. 2005
    ..Events and secular trends influencing birth cohorts may not be adequately addressed, thereby limiting the interpretation and implications of the findings. Research in nonhuman primates may help uncover underlying mechanisms...
  87. pmc Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph)
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Blood 109:3479-88. 2007
    ..0; 95% CI = 1.6-5.6). The pattern of NHL heritability appeared to be uniform across NHL subtypes, but risk patterns differed by specific hematopoietic malignancies and the sex of the relative, revealing critical clues to disease etiology...
  88. pmc microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis
    Aaron E Hoffman
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer Res 69:5970-7. 2009
    ....
  89. ncbi request reprint Regular use of hair dyes and risk of lymphoma in Spain
    Yolanda Benavente
    Servei d Epidemiologia and Registre del Cancer, IDIBELL, Institut Catala d Oncologia, Barcelona, Spain
    Int J Epidemiol 34:1118-22. 2005
    ..The use of hair dyes has been inconsistently associated with an increased risk of lymphomas. We explore hair dye use and lymphoma risk in a case-control study in Spain...
  90. ncbi request reprint Older age predicts a decline in adjuvant chemotherapy recommendations for patients with breast carcinoma: evidence from a tertiary care cohort of chemotherapy-eligible patients
    Angela DeMichele
    Division of Hematology Oncology, Department of Medicine, and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer 97:2150-9. 2003
    ....
  91. pmc Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium
    Silvia de Sanjose
    Unit of Infections and Cancer, Catalan Institute of Oncology, Institut d Investigacio Biomedica de Bellvitge, Centro de Investigación Biomédica en Red Epidemiología y Salud Pública, Barcelona, Spain
    Clin Gastroenterol Hepatol 6:451-8. 2008
    ..We pooled case-control study data to provide robust estimates of the risk of non-Hodgkin's lymphoma (NHL) subtypes after HCV infection...
  92. ncbi request reprint Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA
    Zhongxing Liang
    Department of Radiology, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA
    Biochem Biophys Res Commun 363:542-6. 2007
    ..These data support the conclusion that miRNA against CXCR4 can serve as an alterative means of therapy to lower CXCR4 expression and to block the invasion and metastasis of breast cancer cells...
  93. ncbi request reprint Pattern of lymph node metastases in patients with squamous cell carcinoma of the thoracic esophagus who underwent three-field lymphadenectomy
    Hecheng Li
    Department of Thoracic Surgery, Cancer Hospital of Fudan University, and Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
    Eur Surg Res 39:1-6. 2007
    ..The purpose of the present study was to explore the pattern of lymph node metastasis and factors that are correlated with lymph node metastasis in patients with esophageal cancer who underwent three-field lymphadenectomy...
  94. ncbi request reprint Changing incidence of thyroid cancer
    Yawei Zhang
    JAMA 296:1350; author reply 1350. 2006
  95. ncbi request reprint Re: No increased risk of non-Hodgkin's lymphoma with steroids, estrogens and psychotropics (Netherlands)
    Tongzhang Zheng
    Cancer Causes Control 15:433-4. 2004
  96. ncbi request reprint A time-to-prescription-refill measure of antiretroviral adherence predicted changes in viral load in HIV
    Robert Grossberg
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 57:1107-10. 2004
    ..The goal of this study was to determine the validity and utility of a pharmacy-based time-to-refill measure of antiretroviral therapy adherence...
  97. ncbi request reprint Facility-level variation in antibiotic prescriptions for veterans with upper respiratory infections
    Sherrie L Aspinall
    Center for Health Equity Research and Promotion, Veterans Affairs Healthcare System, Pittsburgh, USA
    Clin Ther 27:258-62. 2005
    ..Programs have targeted individual patient and physician behaviors to reduce the use of antibiotics for upper respiratory infections (URIs), but such efforts have had limited success to date...

Research Grants2

  1. Quality of Life of Testicular Cancer Survivors
    Yawei Zhang; Fiscal Year: 2007
    ..The increasing incidence of TC in young men, and the high survival rate, makes understanding the morbidity associated with TC survival a public health priority. ..