Guido Wollmann

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Targeting human glioblastoma cells: comparison of nine viruses with oncolytic potential
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 79:6005-22. 2005
  2. ncbi request reprint Direct excitation of hypocretin/orexin cells by extracellular ATP at P2X receptors
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, Connecticut 06520, USA
    J Neurophysiol 94:2195-206. 2005
  3. ncbi request reprint Voltage-dependent ion channels in the mouse RPE: comparison with Norrie disease mice
    Guido Wollmann
    Institut fuer Klinische Physiologie, Charite Universitaetsmedizin Berlin, Campus Benjamin Franklin, Germany
    Vision Res 46:688-98. 2006
  4. pmc Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 81:1479-91. 2007
  5. pmc Oncolytic virus therapy for glioblastoma multiforme: concepts and candidates
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA
    Cancer J 18:69-81. 2012
  6. pmc Some attenuated variants of vesicular stomatitis virus show enhanced oncolytic activity against human glioblastoma cells relative to normal brain cells
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 84:1563-73. 2010
  7. pmc Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain
    Anthony N van den Pol
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 81:332-48. 2007
  8. pmc Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression
    Anthony N van den Pol
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 516:456-81. 2009
  9. ncbi request reprint Systemic vesicular stomatitis virus selectively destroys multifocal glioma and metastatic carcinoma in brain
    Koray Ozduman
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Neurosci 28:1882-93. 2008
  10. pmc Vesicular stomatitis virus variants selectively infect and kill human melanomas but not normal melanocytes
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA
    J Virol 87:6644-59. 2013

Detail Information

Publications14

  1. pmc Targeting human glioblastoma cells: comparison of nine viruses with oncolytic potential
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 79:6005-22. 2005
    ..Together, these data suggest that four (VSV, Sindbis virus, MVMi, and MVMp) of the nine viruses studied merit further analysis for potential therapeutic actions on glioblastoma...
  2. ncbi request reprint Direct excitation of hypocretin/orexin cells by extracellular ATP at P2X receptors
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, Connecticut 06520, USA
    J Neurophysiol 94:2195-206. 2005
    ..Together, these results show a depolarizing response to extracellular ATP that would lead to an increased activity of the hypocretin arousal system...
  3. ncbi request reprint Voltage-dependent ion channels in the mouse RPE: comparison with Norrie disease mice
    Guido Wollmann
    Institut fuer Klinische Physiologie, Charite Universitaetsmedizin Berlin, Campus Benjamin Franklin, Germany
    Vision Res 46:688-98. 2006
    ..Although no significant differences were observed, our study provides a base for future studies on ion channel function and dysfunction in transgenic mouse models...
  4. pmc Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 81:1479-91. 2007
    ..Together, our results demonstrate that activation of the interferon pathway protects normal human brain cells from VSV infection while maintaining the vulnerability of human glioblastoma cells to viral destruction...
  5. pmc Oncolytic virus therapy for glioblastoma multiforme: concepts and candidates
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA
    Cancer J 18:69-81. 2012
    ....
  6. pmc Some attenuated variants of vesicular stomatitis virus show enhanced oncolytic activity against human glioblastoma cells relative to normal brain cells
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 84:1563-73. 2010
    ..We concluded that some, but not all, attenuated VSV mutants display a favorable oncolytic profile and merit further investigation...
  7. pmc Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain
    Anthony N van den Pol
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    J Virol 81:332-48. 2007
    ..These results suggest that coupling IFN administration with current treatments may reduce CMV infections in the developing brain...
  8. pmc Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression
    Anthony N van den Pol
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 516:456-81. 2009
    ..DG-VSVs with genes coding for different color reporters allow multicolor visualization of neurons wherever applied...
  9. ncbi request reprint Systemic vesicular stomatitis virus selectively destroys multifocal glioma and metastatic carcinoma in brain
    Koray Ozduman
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Neurosci 28:1882-93. 2008
    ..Quantitative PCR analysis of how VSVrp30a selectively infected tumor cells suggested multiple mechanisms, including cell surface binding and internalization...
  10. pmc Vesicular stomatitis virus variants selectively infect and kill human melanomas but not normal melanocytes
    Guido Wollmann
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA
    J Virol 87:6644-59. 2013
    ..Similar to human melanocytes, mouse melanocytes resisted VSV-rp30 infection. This study confirms the general susceptibility of the majority of human melanoma types for VSV-mediated oncolysis...
  11. pmc Peripheral immunization blocks lethal actions of vesicular stomatitis virus within the brain
    Koray Ozduman
    Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA
    J Virol 83:11540-9. 2009
    ..These results indicate that attenuated recombinant viruses show reduced neurovirulence and that peripheral immunization blocks the lethal actions of all VSVs tested...
  12. doi request reprint Rostral midbrain infarction producing isolated lateropulsion
    Joachim M Baehring
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT 06510, USA
    Neurology 70:655-6. 2008
  13. ncbi request reprint Effects of protein kinase C on delayed rectifier K+ channel regulation by tyrosine kinase in rat retinal pigment epithelial cells
    Olaf Strauss
    Institute for Clinical Physiology, Benjamin Franklin University Clinic, Free University of Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    Invest Ophthalmol Vis Sci 43:1645-54. 2002
    ..Investigation of the regulation of delayed rectifier potassium channels by protein kinases in retinal pigment epithelial (RPE) cells...
  14. ncbi request reprint Differential regulation of gene expression of neurotensin and prohormone convertases PC1 and PC2 in the bovine ocular ciliary epithelium: possible implications on neurotensin processing
    Javier Ortego
    Yale University School of Medicine, Department of Ophthalmology and Visual Science, 330 Cedar Street, New Haven, CT 06510, USA
    Neurosci Lett 333:49-53. 2002
    ..PC1 and PC2 mRNA expression was induced in a cell-specific manner by the same agents that enhanced pro-NT/NN biosynthesis. These results demonstrate cell-specific processing of pro-NT/NN by the ciliary epithelium...