N M Wikonkal

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Ultraviolet radiation induced signature mutations in photocarcinogenesis
    N M Wikonkal
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut, USA
    J Investig Dermatol Symp Proc 4:6-10. 1999
  2. ncbi request reprint The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes
    D E Brash
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Conneticut 06520 8040, USA
    J Invest Dermatol 117:1234-40. 2001
  3. ncbi request reprint Induction of cyclin-dependent kinase inhibitors and G(1) prolongation by the chemopreventive agent N-acetylcysteine
    M Liu
    Department of Therapeutic Radiology and Department of Genetics, Yale University School of Medicine, New Haven, CT 06520 8040, USA
    Carcinogenesis 20:1869-72. 1999
  4. pmc Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations
    W Zhang
    Department of Therapeutic Radiology Yale School of Medicine, P.O. Box 208040, New Haven, CT 06520-8040, USA
    Proc Natl Acad Sci U S A 98:13948-53. 2001

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Ultraviolet radiation induced signature mutations in photocarcinogenesis
    N M Wikonkal
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut, USA
    J Investig Dermatol Symp Proc 4:6-10. 1999
    ..Thus cancer involves both a single-cell problem and a multi-cell problem; in skin cancer, sunlight appears to drive both...
  2. ncbi request reprint The DNA damage signal for Mdm2 regulation, Trp53 induction, and sunburn cell formation in vivo originates from actively transcribed genes
    D E Brash
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Conneticut 06520 8040, USA
    J Invest Dermatol 117:1234-40. 2001
    ..DNA photoproducts in actively transcribed genes were involved in approximately 89% of the Mdm2 response...
  3. ncbi request reprint Induction of cyclin-dependent kinase inhibitors and G(1) prolongation by the chemopreventive agent N-acetylcysteine
    M Liu
    Department of Therapeutic Radiology and Department of Genetics, Yale University School of Medicine, New Haven, CT 06520 8040, USA
    Carcinogenesis 20:1869-72. 1999
    ..An antioxidant whose action is limited to scavenging radicals, Trolox, does not induce G(1) arrest. Taken together, these results suggest a potential novel molecular basis for chemoprevention by NAC...
  4. pmc Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations
    W Zhang
    Department of Therapeutic Radiology Yale School of Medicine, P.O. Box 208040, New Haven, CT 06520-8040, USA
    Proc Natl Acad Sci U S A 98:13948-53. 2001
    ....