Genomes and Genes
Scott D Weatherbee
Affiliation: Yale University
- Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversificationScott D Weatherbee
Department of Developmental Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Proc Natl Acad Sci U S A 103:15103-7. 2006....
- Mammalian limbs take flightScott D Weatherbee
Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA
Dev Cell 14:149-50. 2008..In an attempt to understand factors influencing this diversity, Cretekos and colleagues, in a recent issue of Genes & Development, provide molecular insight into the evolution of wing morphology in bats...
- A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signalingScott D Weatherbee
Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
Hum Mol Genet 18:4565-75. 2009..Thus the disruption of Hh signaling can explain many, but not all, of the defects caused by loss of Mks1...
- LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junctionScott D Weatherbee
Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
Development 133:4993-5000. 2006..The identification of Lrp4 as a crucial factor for NMJ formation may have implications for human neuromuscular diseases such as myasthenia syndromes...
- Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signalingKasey J Christopher
Department of Genetics, Yale University, New Haven, CT 06520, USA
Dev Biol 368:382-92. 2012..Together, these studies identify a previously unknown regulator of ciliogenesis and provide insight into how ciliary factors affect Shh signaling and cilia biogenesis in distinct tissues...
- Embryonic staging system for the short-tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive-bred animalsChris J Cretekos
Department of Molecular Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA
Dev Dyn 233:721-38. 2005..This staging system provides a framework for studying Carollia embryogenesis and should prove useful as a guide for embryological studies of other bat species and for comparisons with other orders of mammals...