Paul E Turner

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Evolutionary genomics of host-use in bifurcating demes of RNA virus phi-6
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    BMC Evol Biol 12:153. 2012
  2. ncbi request reprint Escape from Prisoner's Dilemma in RNA phage phi6
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Am Nat 161:497-505. 2003
  3. doi request reprint High-throughput analysis of growth differences among phage strains
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    J Microbiol Methods 88:117-21. 2012
  4. doi request reprint Role of evolved host breadth in the initial emergence of an RNA virus
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Evolution 64:3273-86. 2010
  5. pmc Phenotypic plasticity in bacterial plasmids
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Genetics 167:9-20. 2004
  6. ncbi request reprint Searching for the advantages of virus sex
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA
    Orig Life Evol Biosph 33:95-108. 2003
  7. pmc Evolution of mutational robustness in an RNA virus
    Rebecca Montville
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS Biol 3:e381. 2005
  8. ncbi request reprint Evolution of host specificity drives reproductive isolation among RNA viruses
    Siobain Duffy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Evolution 61:2614-22. 2007
  9. ncbi request reprint Host density impacts relative fitness of bacteriophage Phi6 genotypes in structured habitats
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
    Evolution 61:2516-27. 2007
  10. ncbi request reprint Virus population extinction via ecological traps
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Ecol Lett 10:230-40. 2007

Detail Information

Publications27

  1. pmc Evolutionary genomics of host-use in bifurcating demes of RNA virus phi-6
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    BMC Evol Biol 12:153. 2012
    ..The resulting tree yielded 32 clones at the tips and internal nodes; these strains were fully sequenced and measured for phenotypic changes in selected traits (fitness on original and novel hosts)...
  2. ncbi request reprint Escape from Prisoner's Dilemma in RNA phage phi6
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Am Nat 161:497-505. 2003
    ..We discuss mechanisms that may afford selfish genotypes an advantage during intrahost competition and the relevance in our system for alternative ecological interactions among viruses...
  3. doi request reprint High-throughput analysis of growth differences among phage strains
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    J Microbiol Methods 88:117-21. 2012
    ....
  4. doi request reprint Role of evolved host breadth in the initial emergence of an RNA virus
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Evolution 64:3273-86. 2010
    ..We discuss evolution of phenotypic plasticity versus environmental robustness in viruses, virus avoidance of extinction, and surveillance of pathogen niche breadth to predict future likelihood of emergence...
  5. pmc Phenotypic plasticity in bacterial plasmids
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Genetics 167:9-20. 2004
    ..I discuss adaptive vs. nonadaptive causes for the phenotypic plasticity, as well as potential mechanisms that may lead to complex transfer dynamics of plasmids in liquid environments...
  6. ncbi request reprint Searching for the advantages of virus sex
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA
    Orig Life Evol Biosph 33:95-108. 2003
    ..Here I discuss various explanations for the evolution of segmentation in RNA viruses, and the added cost of sex when large numbers of viruses co-infect the same cell...
  7. pmc Evolution of mutational robustness in an RNA virus
    Rebecca Montville
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS Biol 3:e381. 2005
    ..In addition, we observed higher mutation frequencies in the more robust viruses, indicating that evolution of robustness might foster less-accurate genome replication in RNA viruses...
  8. ncbi request reprint Evolution of host specificity drives reproductive isolation among RNA viruses
    Siobain Duffy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Evolution 61:2614-22. 2007
    ..Furthermore, our data confirm the biological credibility of simple "no-gene" mechanisms of assortative mating, in which this trait arises as a pleiotropic effect of genes responsible for ecological adaptation...
  9. ncbi request reprint Host density impacts relative fitness of bacteriophage Phi6 genotypes in structured habitats
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
    Evolution 61:2516-27. 2007
    ..We discuss the relevance of our findings for selection occurring in natural phage populations and for the general evolutionary epidemiology of infectious parasites...
  10. ncbi request reprint Virus population extinction via ecological traps
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Ecol Lett 10:230-40. 2007
    ..We conclude that the ecological concepts applied to species conservation in altered landscapes can also contribute to the development of trap cell therapies for infectious human viruses...
  11. ncbi request reprint Viral ecology and the maintenance of novel host use
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Am Nat 167:429-39. 2006
    ..We argue that this effect should facilitate adaptation by the virus to utilize the novel host--often crucial in subsequent phases of emergence...
  12. pmc Co-infection weakens selection against epistatic mutations in RNA viruses
    Remy Froissart
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Genetics 168:9-19. 2004
    ..We discuss our results in light of virus disease management and the evolutionary advantage of haploidy in biological populations...
  13. pmc Robustness promotes evolvability of thermotolerance in an RNA virus
    Robert C McBride
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
    BMC Evol Biol 8:231. 2008
    ..However, the true effect of genetic robustness on evolvability in biological systems remains uncertain...
  14. doi request reprint Geographic differences in sexual reassortment in RNA phage
    Kara J O'Keefe
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
    Evolution 64:3010-23. 2010
    ..We discuss possible explanations for these conflicting results across the studies, such as differing local ecology and its impact on phage growth, and geographic differences in selection against hybrid phage genotypes...
  15. ncbi request reprint DNA secretion and gene-level selection in bacteria
    Jeremy A Draghi
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Microbiology 152:2683-8. 2006
    ..This analysis confirms that the secretion of DNA from intact bacterial cells is fully explicable with evolutionary theory, and reveals a novel mechanism for bacterial evolution...
  16. pmc Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme
    Moshe Dessau
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America
    PLoS Genet 8:e1003102. 2012
    ....
  17. pmc Bacteriophage migration via nematode vectors: host-parasite-consumer interactions in laboratory microcosms
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, 165 Prospect St, P O Box 208106, New Haven, CT 06520 8106, USA
    Appl Environ Microbiol 72:1974-9. 2006
    ..We discuss the microbial growth dynamics that underlie these results, suggest mechanistic explanations for nematode transmission of phages, and propose intriguing possibilities for future research...
  18. pmc Pleiotropic costs of niche expansion in the RNA bacteriophage phi 6
    Siobain Duffy
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
    Genetics 172:751-7. 2006
    ..The possibility for cost-free niche expansion implies that varied ecological conditions may favor host shifts in RNA viruses...
  19. pmc Reduced fecundity is the cost of cheating in RNA virus phi6
    John J Dennehy
    Department of Ecology and Evolutionary Biology, Yale University, PO Box 208106, New Haven, CT 06520, USA
    Proc Biol Sci 271:2275-82. 2004
    ..Our data suggest that interference competition allows high fitness of derived cheaters in mixed infections, and we discuss preferential encapsidation as one possible mechanism...
  20. pmc On the possible role of robustness in the evolution of infectious diseases
    C Brandon Ogbunugafor
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Chaos 20:026108. 2010
    ....
  21. pmc Combining mathematics and empirical data to predict emergence of RNA viruses that differ in reservoir use
    C Brandon Ogbunugafor
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Philos Trans R Soc Lond B Biol Sci 365:1919-30. 2010
    ....
  22. doi request reprint Evolution of increased survival in RNA viruses specialized on cancer-derived cells
    C Brandon Ogbunugafor
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Am Nat 181:585-95. 2013
    ..Our results shed new light on the causes and consequences of "sit and wait" infection strategies in RNA viruses...
  23. doi request reprint Stochastic temperatures impede RNA virus adaptation
    Barry W Alto
    Florida Medical Entomology Laboratory, University of Florida, Vero Beach, Florida 32962, USA
    Evolution 67:969-79. 2013
    ....
  24. doi request reprint Yeast response to LA virus indicates coadapted global gene expression during mycoviral infection
    Robert C McBride
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    FEMS Yeast Res 13:162-79. 2013
    ....
  25. ncbi request reprint Optimal bacteriophage mutation rates for phage therapy
    David T Kysela
    Department of Ecology and Evolutionary Biology, Yale University, P O Box 208106, New Haven, CT 06520 8106, USA
    J Theor Biol 249:411-21. 2007
    ..01). Increases to the mutation rate beyond the optimal value at mutation-selection balance may therefore prove generally undesirable...
  26. doi request reprint Evolutionary genomics of host adaptation in vesicular stomatitis virus
    Susanna K Remold
    Department of Biology, University of Louisville, USA
    Mol Biol Evol 25:1138-47. 2008
    ..We discuss the degree to which current genetic architecture is expected to constrain future evolution of complex traits, such as host use by RNA viruses...
  27. pmc Widespread genetic exchange among terrestrial bacteriophages
    Olin K Silander
    Department of Biological Sciences, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 102:19009-14. 2005
    ..This extraordinary rate of genetic exchange between highly unrelated individuals is unprecedented in any taxa. We discuss our results in light of the biological species concept applied to viruses...