Lyuben Tsvetkov

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Polo-like kinases and Chk2 at the interface of DNA damage checkpoint pathways and mitotic regulation
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06510, USA
    IUBMB Life 56:449-56. 2004
  2. ncbi Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06510, USA
    Cell Cycle 4:166-71. 2005
  3. ncbi Interaction of chromatin-associated Plk1 and Mcm7
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06511, USA
    J Biol Chem 280:11943-7. 2005
  4. pmc Centrosomal Chk2 in DNA damage responses and cell cycle progression
    Amnon Golan
    Department of Pathology, Yale School of Medicine, New Haven, CT, USA
    Cell Cycle 9:2647-56. 2010
  5. ncbi Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06511, USA
    J Biol Chem 278:8468-75. 2003

Collaborators

Detail Information

Publications5

  1. ncbi Polo-like kinases and Chk2 at the interface of DNA damage checkpoint pathways and mitotic regulation
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06510, USA
    IUBMB Life 56:449-56. 2004
    ..These effects are achieved by affecting key players of the basic cell cycle regulation of the cells with damaged DNA. This review is focused on the interplay between Chk2, a bona fide checkpoint protein kinase, and Polo-like kinases...
  2. ncbi Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06510, USA
    Cell Cycle 4:166-71. 2005
    ..These data suggest a participation of DNA damage checkpoints in regulation of the signaling pathways upstream of Plk1...
  3. ncbi Interaction of chromatin-associated Plk1 and Mcm7
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06511, USA
    J Biol Chem 280:11943-7. 2005
    ..The strongest interaction between endogenous Plk1 and Mcm7 was detected in a soluble chromatin fraction. These findings suggest a new function for Plk1 in coordination of DNA replication and mitotic events...
  4. pmc Centrosomal Chk2 in DNA damage responses and cell cycle progression
    Amnon Golan
    Department of Pathology, Yale School of Medicine, New Haven, CT, USA
    Cell Cycle 9:2647-56. 2010
    ..These and other data suggest a model in which binding of Chk2 to the centrosome at multiple cell cycle junctures controls co-localization of Chk2 with other cell cycle and centrosomal regulators...
  5. ncbi Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody
    Lyuben Tsvetkov
    Department of Pathology, School of Medicine, Yale University, New Haven, Connecticut 06511, USA
    J Biol Chem 278:8468-75. 2003
    ..These findings suggest lateral communication between the DNA damage and mitotic checkpoints...