Navtej Toor

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Identification of a family of group II introns encoding LAGLIDADG ORFs typical of group I introns
    Navtej Toor
    RNA 8:1373-7. 2002
  2. doi request reprint Crystal structure of a self-spliced group II intron
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, Bass Building, New Haven, CT 06511, USA
    Science 320:77-82. 2008
  3. pmc Tertiary architecture of the Oceanobacillus iheyensis group II intron
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511, USA
    RNA 16:57-69. 2010
  4. pmc A structural analysis of the group II intron active site and implications for the spliceosome
    Kevin S Keating
    Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut 06520, USA
    RNA 16:1-9. 2010
  5. pmc Structural insights into RNA splicing
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA
    Curr Opin Struct Biol 19:260-6. 2009
  6. pmc Structural basis for exon recognition by a group II intron
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, Connecticut 06520, USA
    Nat Struct Mol Biol 15:1221-2. 2008
  7. pmc The GANC tetraloop: a novel motif in the group IIC intron structure
    Kevin S Keating
    Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA
    J Mol Biol 383:475-81. 2008
  8. pmc Database for mobile group II introns
    Lixin Dai
    Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada
    Nucleic Acids Res 31:424-6. 2003
  9. pmc Self-splicing of a group IIC intron: 5' exon recognition and alternative 5' splicing events implicate the stem-loop motif of a transcriptional terminator
    Navtej Toor
    Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada
    Nucleic Acids Res 34:6461-71. 2006

Collaborators

Detail Information

Publications9

  1. pmc Identification of a family of group II introns encoding LAGLIDADG ORFs typical of group I introns
    Navtej Toor
    RNA 8:1373-7. 2002
    ..Therefore, introns should not be assumed to be group I introns based solely on the presence of a LAGLIDADG ORF...
  2. doi request reprint Crystal structure of a self-spliced group II intron
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, Bass Building, New Haven, CT 06511, USA
    Science 320:77-82. 2008
    ..Structural and functional analogies support the hypothesis that group II introns and the spliceosome share a common ancestor...
  3. pmc Tertiary architecture of the Oceanobacillus iheyensis group II intron
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511, USA
    RNA 16:57-69. 2010
    ..As predicted from biochemical and genetic studies, the group II intron provides a wealth of new information on strategies for RNA folding and tertiary structural organization...
  4. pmc A structural analysis of the group II intron active site and implications for the spliceosome
    Kevin S Keating
    Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut 06520, USA
    RNA 16:1-9. 2010
    ..This analysis leads to a set of predictions for the molecular structure of the spliceosomal active site...
  5. pmc Structural insights into RNA splicing
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA
    Curr Opin Struct Biol 19:260-6. 2009
    ..Here, we compare structures and catalytic mechanisms of self-splicing RNAs and we discuss the possible implications for spliceosomal reaction mechanisms...
  6. pmc Structural basis for exon recognition by a group II intron
    Navtej Toor
    Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, Connecticut 06520, USA
    Nat Struct Mol Biol 15:1221-2. 2008
    ..The structure of the complex reveals the conformation of motifs involved in exon recognition by group II introns...
  7. pmc The GANC tetraloop: a novel motif in the group IIC intron structure
    Kevin S Keating
    Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA
    J Mol Biol 383:475-81. 2008
    ..These structural attributes allow GANC tetraloops to fit precisely within the group IIC intron core, thereby demonstrating that structural motifs can adapt to function in a specific niche...
  8. pmc Database for mobile group II introns
    Lixin Dai
    Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada
    Nucleic Acids Res 31:424-6. 2003
    ..The comparative data should facilitate study of the function, spread and evolution of group II introns. The database can be accessed at http://www.fp.ucalgary.ca/group2introns/...
  9. pmc Self-splicing of a group IIC intron: 5' exon recognition and alternative 5' splicing events implicate the stem-loop motif of a transcriptional terminator
    Navtej Toor
    Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada
    Nucleic Acids Res 34:6461-71. 2006
    ....