Research Topics
| Mary TinettiSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Evaluation of restorative care vs usual care for older adults receiving an acute episode of home careMary E Tinetti
JAMA 287:2098-105. 2002..Illness and hospitalization often trigger functional decline among older persons. Home care services implemented for functional decline provide an opportunity to intervene to improve outcomes...
Geriatric syndromes: clinical, research, and policy implications of a core geriatric conceptSharon K Inouye
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
J Am Geriatr Soc 55:780-91. 2007..National strategic initiatives are required to overcome barriers and to achieve clinical, research, and policy advances that will improve quality of life for older persons...
Association between antihypertensive medication use and non-cardiovascular outcomes in older menJoseph V Agostini
Clinical Epidemiology Research Center 151B, VA Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT, USA
J Gen Intern Med 22:1661-7. 2007....
Contribution of individual diseases to death in older adults with multiple diseasesMary E Tinetti
Department of Internal Medicine, School of Medicine, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 60:1448-56. 2012..To determine empirically the diseases contributing most commonly and strongly to death in older adults, accounting for coexisting diseases...
Effect of a restorative model of posthospital home care on hospital readmissionsMary E Tinetti
Department of Medicine, Yale School of Medicine, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 60:1521-6. 2012..To compare readmissions of Medicare recipients of usual home care and a matched group of recipients of a restorative model of home care...
Effect of chronic disease-related symptoms and impairments on universal health outcomes in older adultsMary E Tinetti
Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut 06520 8025, USA
J Am Geriatr Soc 59:1618-27. 2011..To determine the extent to which disease-related symptoms and impairments, which constitute measures of disease severity or targets of therapy, account for the associations between chronic diseases and universal health outcomes...
The patient who falls: "It's always a trade-off"Mary E Tinetti
Department of Internal Medicine, Yale University School of Medicine Section of Geriatrics, 333 Cedar St, PO Box 208025, New Haven, CT 06520, USA
JAMA 303:258-66. 2010..While challenges and barriers exist, fall prevention strategies can be incorporated into clinical practice...
Effect of dissemination of evidence in reducing injuries from fallsMary E Tinetti
Department of Medicine, Yale School of Medicine, New Haven, CT, USA
N Engl J Med 359:252-61. 2008..Falling is a common and morbid condition among elderly persons. Effective strategies to prevent falls have been identified but are underutilized...
Health outcome priorities among competing cardiovascular, fall injury, and medication-related symptom outcomesMary E Tinetti
Department of Internal Medicine and Epidemiology, New Haven, Connecticut 06504, USA
J Am Geriatr Soc 56:1409-16. 2008..To determine the priority that older adults with coexisting hypertension and fall risk give to optimizing cardiovascular outcomes versus fall- and medication symptom-related outcomes...
Fall-risk evaluation and management: challenges in adopting geriatric care practicesMary E Tinetti
Department of Internal Medicine, Yale University School of Medicine, 20 York St, TMP15, New Haven, CT 06504, USA
Gerontologist 46:717-25. 2006....
Development of a tool for eliciting patient priority from among competing cardiovascular disease, medication-symptoms, and fall injury outcomesMary E Tinetti
Department of Medicine, Section of Geriatrics, New Haven, Connecticut 06520 8025, USA
J Am Geriatr Soc 56:730-6. 2008..To develop a choice task for eliciting priorities in the face of competing cardiovascular disease (CVD) outcomes, medication-related symptoms, and fall injuries...
The end of the disease eraMary E Tinetti
Departments of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06520 8025, USA
Am J Med 116:179-85. 2004..Notwithstanding these barriers, medical care must evolve to meet the health care needs of patients in the 21st century...
Modifiable impairments predict progressive disability among older personsMary E Tinetti
Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06504, USA
J Aging Health 17:239-56. 2005..Our purpose was to determine the extent to which a predetermined set of modifiable impairments predicted progression of disability...
Contribution of multiple chronic conditions to universal health outcomesMary E Tinetti
Department of Medicine, School of MedicineSchool of Public Health, Yale University, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 59:1686-91. 2011..To determine the relative effect of five chronic conditions on four representative universal health outcomes...
Pilot testing of intervention protocols to prevent pneumonia in nursing home residentsVincent Quagliarello
Department of Internal Medicine, Infectious Diseases Section, School of Medicine, Yale University, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 57:1226-31. 2009..To test intervention protocols for feasibility, staff adherence, and effectiveness in reducing pneumonia risk factors (impaired oral hygiene, swallowing difficulty) in nursing home residents...
Interobserver variability in the assessment of clinical criteria for suspected urinary tract infection in nursing home residentsManisha Juthani-Mehta
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
Infect Control Hosp Epidemiol 29:446-9. 2008..Pairs of nursing home staff caring for 30 residents were interviewed at the time UTI was suspected. At least one measure from each of 7 clinical criteria categories was reliably assessed by nursing home staff members...
Clinical features to identify urinary tract infection in nursing home residents: a cohort studyManisha Juthani-Mehta
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Am Geriatr Soc 57:963-70. 2009..To identify clinical features associated with bacteriuria plus pyuria in noncatheterized nursing home residents with clinically suspected urinary tract infection (UTI)...
Health outcome prioritization to elicit preferences of older persons with multiple health conditionsTerri R Fried
Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
Patient Educ Couns 83:278-82. 2011..To develop and test a simple tool to elicit the preferences of older persons based on prioritization of universal health outcomes...
Diagnostic accuracy of criteria for urinary tract infection in a cohort of nursing home residentsManisha Juthani-Mehta
Department of Internal Medicine, Section of Infectious Disease, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 55:1072-7. 2007....
Dissemination of an evidence-based multicomponent fall risk-assessment and -management strategy throughout a geographic areaDorothy I Baker
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut
J Am Geriatr Soc 53:675-80. 2005..Project results have implications for efforts to diffuse evidence-based practices for multifactorial geriatric conditions such as falls...
The impact of chronic illnesses on the use and effectiveness of adjuvant chemotherapy for colon cancerCary P Gross
Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Cancer 109:2410-9. 2007..It is unclear how noncancer conditions affect the use or effectiveness of adjuvant therapy among older patients with colon cancer...
Range and severity of symptoms over time among older adults with chronic obstructive pulmonary disease and heart failureLisa M Walke
Yale School of Medicine, New Haven, CT 06504, USA
Arch Intern Med 167:2503-8. 2007..Symptoms are a central component of health status; however, little is known about the full range and trajectory of symptoms experienced by persons with chronic diseases other than cancer...
Assessing multiple medication use with probabilities of benefits and harmsTerrence E Murphy
Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA
J Aging Health 20:694-709. 2008..A quantitative framework to assess harms and benefits of candidate medications in the context of drugs that a patient is already taking is proposed...
Views of older persons with multiple morbidities on competing outcomes and clinical decision-makingTerri R Fried
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Am Geriatr Soc 56:1839-44. 2008....
Primary care clinicians' experiences with treatment decision making for older persons with multiple conditionsTerri R Fried
Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA
Arch Intern Med 171:75-80. 2011..Understanding how primary care clinicians approach treatment decision making for these patients is critical to the design of interventions to improve the decision-making process...
Effects of statin use on muscle strength, cognition, and depressive symptoms in older adultsJoseph V Agostini
Clinical Epidemiology Research Center, VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
J Am Geriatr Soc 55:420-5. 2007..To determine the relationship between hydroxymethyl glutaryl coenzyme A reductase inhibitor (statin) use and proximal muscle strength, cognition, and depression in older adults...
Multimorbidity and survival in older persons with colorectal cancerCary P Gross
General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 54:1898-904. 2006..To ascertain the effect of common chronic conditions on mortality in older persons with colorectal cancer...
Nursing home practitioner survey of diagnostic criteria for urinary tract infectionsManisha Juthani-Mehta
Infectious Diseases Section, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 53:1986-90. 2005..To determine practitioner knowledge of the most commonly used consensus criteria (i.e., McGeer criteria) for UTIs...
Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromesHeather G Allore
Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA
Clin Trials 2:13-21. 2005..We also propose elements of multicomponent interventions for multifactorial health conditions that should be reported in publications and areas where future research is needed...
A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scoresHeather Allore
Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
J Clin Epidemiol 58:154-61. 2005..Therefore, methods to detect levels of a predictor variable that predict the outcome and determine the threshold for clinical intervention would provide a beneficial tool for clinical investigators and epidemiologists...
Perceptions of physicians on the barriers and facilitators to integrating fall risk evaluation and management into practiceWilliam C Chou
Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
J Gen Intern Med 21:117-22. 2006..Falls are common, treatable, and result in considerable morbidity in older adults. However, fall risk factor evaluation and management targeted at high-risk patients is largely neglected in clinical practice...
Potential pitfalls of disease-specific guidelines for patients with multiple conditionsMary E Tinetti
Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA
N Engl J Med 351:2870-4. 2004
The burden of symptoms among community-dwelling older persons with advanced chronic diseaseLisa M Walke
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06504, USA
Arch Intern Med 164:2321-4. 2004..The objectives of our study were to determine (1) the prevalence of a range of symptoms among older persons with advanced chronic disease and (2) whether the prevalence of symptoms is similar across diagnoses...
Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancerCary P Gross
Section of General Internal Medicine, Department of Medicine, Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, Primary Care Center, New Haven, Conn 06520, USA
JAMA 296:2815-22. 2006..Medicare's reimbursement policy was changed in 1998 to provide coverage for screening colonoscopies for patients with increased colon cancer risk, and expanded further in 2001 to cover screening colonoscopies for all individuals...
The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screeningCary P Gross
Robert Wood Johnson Clinical Scholars Program and Primary Care Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Ann Intern Med 145:646-53. 2006..Older adults with shorter life expectancies may receive less benefit from colorectal cancer screening than younger, healthier patients...
The relationship between number of medications and weight loss or impaired balance in older adultsJoseph V Agostini
Clinical Epidemiology Research Center, VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
J Am Geriatr Soc 52:1719-23. 2004..To examine the relationship between cumulative medication exposure and risk of two common manifestations of adverse drug effects: weight loss and impaired balance...
Association between combined interleukin-6 and C-reactive protein levels and pulmonary function in older women: results from the Women's Health and Aging Studies I and IISANDY S CHANG
Section of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Am Geriatr Soc 59:113-9. 2011....
Role of dipstick testing in the evaluation of urinary tract infection in nursing home residentsManisha Juthani-Mehta
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
Infect Control Hosp Epidemiol 28:889-91. 2007..Nursing home dipstick testing effectively excluded the possibility of UTI...
Modifiable risk factors for nursing home-acquired pneumoniaVincent Quagliarello
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8022, USA
Clin Infect Dis 40:1-6. 2005..This study sought to identify modifiable risk factors for pneumonia in elderly nursing home residents...
Views of older adults on patient participation in medication-related decision makingVernee N Belcher
Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520-8025, USA
J Gen Intern Med 21:298-303. 2006..CONCLUSIONS: While evolution to greater patient involvement in medication decision making may be possible, and desirable to some older patients, findings suggest that the transition will be challenging...
Clinical practice. Preventing falls in elderly personsMary E Tinetti
Department of Internal Medicine, Yale University School of Medicine, 333 Cedar St, P.O. Box 208025, New Haven, CT 06520-8025, USA
N Engl J Med 348:42-9. 2003
Over-the-counter sales of statins and other drugs for asymptomatic conditionsMary E Tinetti
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
N Engl J Med 358:2728-32. 2008
Fall-risk assessment and management in clinical practice: views from healthcare providersRichard H Fortinsky
Center on Aging, University of Connecticut Health Center, Farmington, Connecticut 06030 5215, USA
J Am Geriatr Soc 52:1522-6. 2004....
Changes in physical therapy providers' use of fall prevention strategies following a multicomponent behavioral change interventionCynthia J Brown
University of Alabama at Birmingham, VAMC GRECC 11 G Room 8225, 1530 3rd Ave S, Birmingham, AL 35294 0001, USA
Phys Ther 85:394-403. 2005....
Measuring alcohol consumption among older adults: a comparison of available methodsM Carrington Reid
Clinical Epidemiology Unit, VA Connecticut Healthcare System, West Haven, USA
Am J Addict 12:211-9. 2003..Until optimal methods for measuring alcohol exposures in elderly adults are defined, we suggest that a combination of measures be used when obtaining alcohol histories in older persons...
Depressive symptoms as a risk factor for disabling back pain in community-dwelling older personsM Carrington Reid
Division of Geriatrics and Gerontology, Weill Medical College, Cornell University, New York, New York 10021, USA
J Am Geriatr Soc 51:1710-7. 2003..To determine whether the presence of depressive symptoms is an independent risk factor for disabling back pain in community-dwelling older persons...
Extent of implementation of evidence-based fall prevention practices for older patients in home health careRichard H Fortinsky
Center on Aging, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
J Am Geriatr Soc 56:737-43. 2008..HHA-level comparisons hold the potential to illustrate the extent of diffusion of evidence-based fall prevention practices within and between agencies...
Potentially modifiable resident characteristics that are associated with physical or verbal aggression among nursing home residents with dementiaRalph Leonard
CALM-MD, LLC, St Louis Park, MN 55426, USA
Arch Intern Med 166:1295-300. 2006..CONCLUSION: If the associations we have estimated are causal, then treatment of depression, delusions, hallucinations, and constipation may reduce physical aggression among nursing home residents...
Multifactorial fall-prevention strategies: time to retreat or advanceMary E Tinetti
J Am Geriatr Soc 56:1563-5. 2008
Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysisRoland Schmitt
Department of Nephrology, Hannover Medical School, Hannover, Germany
Am J Kidney Dis 52:262-71. 2008..The prevalence of elderly individuals continues to increase over time, as does the incidence of acute kidney injury (AKI). However, it is not known whether age is an important prognostic predictor for renal recovery after an episode of AKI...
The role of pain in the recovery of instrumental and social functioning after hip fractureChristianna S Williams
Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, 725 Martin Luther King Jr Blvd, Campus Box 7590, Chapel Hill, NC 27599 7590, USA
J Aging Health 18:743-62. 2006..The authors examined the association between pain intensity and two functional endpoints-instrumental activities of daily living and social activity participation-after hip fracture...
Drugs and falls: rethinking the approach to medication risk in older adultsJoseph V Agostini
J Am Geriatr Soc 50:1744-5. 2002
Research Grants
- Death as a multifactorial cumulative health event in older adultsMary Tinetti; Fiscal Year: 2009..With baby boomers heading into their late years, accurate estimates of the conditions contributing to mortality are essential for health and economic planning. ..
- Need for tailored clinical trials: hypertension and fall riskMary Tinetti; Fiscal Year: 2006..The proposed study will test this hypothesis. ..
- Claude D. Pepper Older Americans Independence Center at*Mary Tinetti; Fiscal Year: 2006....
- GERIATRIC LEADERSHIP ACADEMIC AWARD (K07)Mary Tinetti; Fiscal Year: 2003..abstract_text> ..
- SHARED IMPAIRMENTS FOR GERIATRIC SYNDROMES & DISABILITYMary Tinetti; Fiscal Year: 2002....
