N Tian

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Synaptic activity, visual experience and the maturation of retinal synaptic circuitry
    Ning Tian
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
    J Physiol 586:4347-55. 2008
  2. ncbi request reprint Visual deprivation alters development of synaptic function in inner retina after eye opening
    N Tian
    Department of Ophthalmology, UCSF School of Medicine, San Francisco, CA 94143, USA
    Neuron 32:439-49. 2001
  3. ncbi request reprint Visual experience and maturation of retinal synaptic pathways
    Ning Tian
    Department of Ophthalmology and Visual Science and Department of Neurobiology, School of Medicine, Yale University, 330 Cedar St, BML 212, New Haven, CT 06520, USA
    Vision Res 44:3307-16. 2004
  4. ncbi request reprint Visual stimulation is required for refinement of ON and OFF pathways in postnatal retina
    Ning Tian
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
    Neuron 39:85-96. 2003
  5. pmc BDNF-Induced potentiation of spontaneous twitching in innervated myocytes requires calcium release from intracellular stores
    R J Kleiman
    Department of Physiology, University of California, San Francisco, California 94143 0723, USA
    J Neurophysiol 84:472-83. 2000
  6. ncbi request reprint Light deprivation suppresses the light response of inner retina in both young and adult mouse
    Setareh Vistamehr
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
    Vis Neurosci 21:23-37. 2004
  7. ncbi request reprint Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate
    Juliette Johnson
    Department of Ophthalmology, University of California School of Medicine, San Francisco, California 94143 0730, USA
    J Neurosci 23:518-29. 2003
  8. pmc Intrinsic ON responses of the retinal OFF pathway are suppressed by the ON pathway
    RENE C RENTERIA
    Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143, USA
    J Neurosci 26:11857-69. 2006
  9. ncbi request reprint Retinal ganglion cell dendrites undergo a visual activity-dependent redistribution after eye opening
    Hong Ping Xu
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 503:244-59. 2007
  10. pmc Glycine receptor-mediated synaptic transmission regulates the maturation of ganglion cell synaptic connectivity
    Hong Ping Xu
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 509:53-71. 2008

Research Grants

Collaborators

Detail Information

Publications13

  1. pmc Synaptic activity, visual experience and the maturation of retinal synaptic circuitry
    Ning Tian
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
    J Physiol 586:4347-55. 2008
    ..Here I will briefly discuss the recent advances in our understanding of how synaptic activity modulates the maturation of RGC synaptic connections...
  2. ncbi request reprint Visual deprivation alters development of synaptic function in inner retina after eye opening
    N Tian
    Department of Ophthalmology, UCSF School of Medicine, San Francisco, CA 94143, USA
    Neuron 32:439-49. 2001
    ..These findings indicate there is a degree of activity-dependent plasticity in the mammalian retina that has not been previously described...
  3. ncbi request reprint Visual experience and maturation of retinal synaptic pathways
    Ning Tian
    Department of Ophthalmology and Visual Science and Department of Neurobiology, School of Medicine, Yale University, 330 Cedar St, BML 212, New Haven, CT 06520, USA
    Vision Res 44:3307-16. 2004
    ..Recently we found that the postnatal maturational processes converting bistratified ON-OFF responsive RGCs to monostratified ON and OFF responsive RGCs depend upon visual stimulation after eye opening...
  4. ncbi request reprint Visual stimulation is required for refinement of ON and OFF pathways in postnatal retina
    Ning Tian
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
    Neuron 39:85-96. 2003
    ..Thus, in retina, there is a previously unrecognized, pathway-specific maturation that is profoundly affected by visual deprivation...
  5. pmc BDNF-Induced potentiation of spontaneous twitching in innervated myocytes requires calcium release from intracellular stores
    R J Kleiman
    Department of Physiology, University of California, San Francisco, California 94143 0723, USA
    J Neurophysiol 84:472-83. 2000
    ..These results suggest that activation of the TrkB receptor activates phospholipase C to initiate intracellular Ca(2+) release from stores which subsequently potentiates transmitter release...
  6. ncbi request reprint Light deprivation suppresses the light response of inner retina in both young and adult mouse
    Setareh Vistamehr
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
    Vis Neurosci 21:23-37. 2004
    ..These results indicate a degree of activity-dependent plasticity in mouse retina that has not been previously described...
  7. ncbi request reprint Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate
    Juliette Johnson
    Department of Ophthalmology, University of California School of Medicine, San Francisco, California 94143 0730, USA
    J Neurosci 23:518-29. 2003
    ..Furthermore, vesicular glutamate transmission likely occurs before ribbon synapse formation in the inner retina...
  8. pmc Intrinsic ON responses of the retinal OFF pathway are suppressed by the ON pathway
    RENE C RENTERIA
    Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143, USA
    J Neurosci 26:11857-69. 2006
    ..Consequently, we propose that a major function of the signaling of the ON pathway to the OFF pathway is suppression of these mistimed, and therefore inappropriate, light-evoked responses...
  9. ncbi request reprint Retinal ganglion cell dendrites undergo a visual activity-dependent redistribution after eye opening
    Hong Ping Xu
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 503:244-59. 2007
    ....
  10. pmc Glycine receptor-mediated synaptic transmission regulates the maturation of ganglion cell synaptic connectivity
    Hong Ping Xu
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 509:53-71. 2008
    ..We interpret these results as that visual stimulation regulates the maturation of RGC synaptic activity and connectivity primarily through GlyR-mediated synaptic transmission...
  11. ncbi request reprint Pathway-specific maturation, visual deprivation, and development of retinal pathway
    Hongping Xu
    Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Neuroscientist 10:337-46. 2004
    ..In addition, both the bipolar cells and cholinergic amacrine cells may provide laminar cues for the maturation of RGC dendritic stratification...
  12. ncbi request reprint Structure of glutamate analogs that activate the ON bipolar cell metabotropic glutamate receptor in vertebrate retina
    Ning Tian
    Department of Ophthalmology and Visual Science and Neurobiology, Yale University School of Medicine, 330 Cedar Street, BML 213, Post Box 208061, New Haven, USA
    Vis Neurosci 20:231-40. 2003
    ..The CoMFA model was used to predict the activity of glutamate analogs and correlations between predicted and measured activity support the model...
  13. pmc Retinopetal axons in mammals: emphasis on histamine and serotonin
    Matthew J Gastinger
    Graduate School of Biomedical Sciences, The University of Texas Health Science Center Houston, Houston, Texas 77225, USA
    Curr Eye Res 31:655-67. 2006
    ..There is also evidence suggesting that retinopetal axons play a role in the etiology of retinal diseases...

Research Grants10

  1. NMDA Receptor and Synaptic Plasticity in Retina
    Ning Tian; Fiscal Year: 2007
    ..The results will also provide insights to how maturation of retinal synaptic circuitry could affect our interpretation of activity-dependent synaptic plasticity in visual cortex. ..
  2. DEVELOPMENT OF SYNAPTIC PATHWAYS IN RETINA
    Ning Tian; Fiscal Year: 2007
    ..They also provide insights to how activity dependent synaptic refinement in retina could affect our interpretation of activity-dependent synaptic plasticity in visual cortex. ..
  3. DEVELOPMENT OF SYNAPTIC PATHWAYS IN RETINA
    Ning Tian; Fiscal Year: 2003
    ..They also provide insights to how neurotransmitter-related therapeutic drugs could affect normal development of the human visual system. ..