Research Topics
| N TianSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Synaptic activity, visual experience and the maturation of retinal synaptic circuitryNing Tian
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
J Physiol 586:4347-55. 2008..Here I will briefly discuss the recent advances in our understanding of how synaptic activity modulates the maturation of RGC synaptic connections...
Visual deprivation alters development of synaptic function in inner retina after eye openingN Tian
Department of Ophthalmology, UCSF School of Medicine, San Francisco, CA 94143, USA
Neuron 32:439-49. 2001..These findings indicate there is a degree of activity-dependent plasticity in the mammalian retina that has not been previously described...- Visual experience and maturation of retinal synaptic pathwaysNing Tian
Department of Ophthalmology and Visual Science and Department of Neurobiology, School of Medicine, Yale University, 330 Cedar St, BML 212, New Haven, CT 06520, USA
Vision Res 44:3307-16. 2004..Recently we found that the postnatal maturational processes converting bistratified ON-OFF responsive RGCs to monostratified ON and OFF responsive RGCs depend upon visual stimulation after eye opening... - Visual stimulation is required for refinement of ON and OFF pathways in postnatal retinaNing Tian
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
Neuron 39:85-96. 2003..Thus, in retina, there is a previously unrecognized, pathway-specific maturation that is profoundly affected by visual deprivation... - BDNF-Induced potentiation of spontaneous twitching in innervated myocytes requires calcium release from intracellular storesR J Kleiman
Department of Physiology, University of California, San Francisco, California 94143 0723, USA
J Neurophysiol 84:472-83. 2000..These results suggest that activation of the TrkB receptor activates phospholipase C to initiate intracellular Ca(2+) release from stores which subsequently potentiates transmitter release... - Light deprivation suppresses the light response of inner retina in both young and adult mouseSetareh Vistamehr
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
Vis Neurosci 21:23-37. 2004..These results indicate a degree of activity-dependent plasticity in mouse retina that has not been previously described... - Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamateJuliette Johnson
Department of Ophthalmology, University of California School of Medicine, San Francisco, California 94143 0730, USA
J Neurosci 23:518-29. 2003..Furthermore, vesicular glutamate transmission likely occurs before ribbon synapse formation in the inner retina... - Intrinsic ON responses of the retinal OFF pathway are suppressed by the ON pathwayRENE C RENTERIA
Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143, USA
J Neurosci 26:11857-69. 2006..Consequently, we propose that a major function of the signaling of the ON pathway to the OFF pathway is suppression of these mistimed, and therefore inappropriate, light-evoked responses... - Retinal ganglion cell dendrites undergo a visual activity-dependent redistribution after eye openingHong Ping Xu
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Comp Neurol 503:244-59. 2007.... - Glycine receptor-mediated synaptic transmission regulates the maturation of ganglion cell synaptic connectivityHong Ping Xu
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Comp Neurol 509:53-71. 2008..We interpret these results as that visual stimulation regulates the maturation of RGC synaptic activity and connectivity primarily through GlyR-mediated synaptic transmission... - Pathway-specific maturation, visual deprivation, and development of retinal pathwayHongping Xu
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Neuroscientist 10:337-46. 2004..In addition, both the bipolar cells and cholinergic amacrine cells may provide laminar cues for the maturation of RGC dendritic stratification... - Structure of glutamate analogs that activate the ON bipolar cell metabotropic glutamate receptor in vertebrate retinaNing Tian
Department of Ophthalmology and Visual Science and Neurobiology, Yale University School of Medicine, 330 Cedar Street, BML 213, Post Box 208061, New Haven, USA
Vis Neurosci 20:231-40. 2003..The CoMFA model was used to predict the activity of glutamate analogs and correlations between predicted and measured activity support the model... - Retinopetal axons in mammals: emphasis on histamine and serotoninMatthew J Gastinger
Graduate School of Biomedical Sciences, The University of Texas Health Science Center Houston, Houston, Texas 77225, USA
Curr Eye Res 31:655-67. 2006..There is also evidence suggesting that retinopetal axons play a role in the etiology of retinal diseases...
Research Grants
- NMDA Receptor and Synaptic Plasticity in RetinaNing Tian; Fiscal Year: 2007..The results will also provide insights to how maturation of retinal synaptic circuitry could affect our interpretation of activity-dependent synaptic plasticity in visual cortex. ..
- DEVELOPMENT OF SYNAPTIC PATHWAYS IN RETINANing Tian; Fiscal Year: 2007..They also provide insights to how activity dependent synaptic refinement in retina could affect our interpretation of activity-dependent synaptic plasticity in visual cortex. ..
- DEVELOPMENT OF SYNAPTIC PATHWAYS IN RETINANing Tian; Fiscal Year: 2003..They also provide insights to how neurotransmitter-related therapeutic drugs could affect normal development of the human visual system. ..