P Z Tan

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Characterization of radioactive metabolites of 5-HT2A receptor PET ligand [18F]altanserin in human and rodent
    P Z Tan
    Yale University School of Medicine, Yale VA Pet Center, West Haven, Connecticut 06511, USA
    Nucl Med Biol 26:601-8. 1999
  2. ncbi request reprint Equilibrium modeling of 5-HT(2A) receptors with [18F]deuteroaltanserin and PET: feasibility of a constant infusion paradigm
    C H van Dyck
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nucl Med Biol 27:715-22. 2000
  3. ncbi request reprint A complete remote-control system for reliable preparation of [18F]altanserin
    P Z Tan
    VA PET Center, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Appl Radiat Isot 50:923-7. 1999
  4. ncbi request reprint Comparison of [(18)F]altanserin and [(18)F]deuteroaltanserin for PET imaging of serotonin(2A) receptors in baboon brain: pharmacological studies
    J K Staley
    Department of Psychiatry, Yale University School of Medicine and VA Connecticut Healthcare System, 06516, West Haven, CT 06516, USA
    Nucl Med Biol 28:271-9. 2001
  5. ncbi request reprint Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: preliminary results of a direct comparison in healthy human subjects
    J D Bremner
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Psychiatry Res 91:79-91. 1999

Collaborators

  • J D Bremner
  • B Roth
  • J K Staley
  • C H van Dyck
  • R B Innis
  • R M Baldwin
  • Q Ramsby
  • H Klump
  • M Al Tikriti
  • P Garg
  • C Ng
  • R Soufer
  • P K Garg
  • L A Amici
  • D S Charney
  • J P Seibyl
  • X Fu
  • J C Soares

Detail Information

Publications5

  1. ncbi request reprint Characterization of radioactive metabolites of 5-HT2A receptor PET ligand [18F]altanserin in human and rodent
    P Z Tan
    Yale University School of Medicine, Yale VA Pet Center, West Haven, Connecticut 06511, USA
    Nucl Med Biol 26:601-8. 1999
    ..We conclude from these studies that the radiometabolites of [18F]altanserin from N-dealkylation and ketone reduction should not interfere with specific receptor quantification in an equilibrium paradigm...
  2. ncbi request reprint Equilibrium modeling of 5-HT(2A) receptors with [18F]deuteroaltanserin and PET: feasibility of a constant infusion paradigm
    C H van Dyck
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nucl Med Biol 27:715-22. 2000
    ..These results demonstrate feasibility of equilibrium imaging with [(18)F]deuteroaltanserin and suggest that it may be superior to [(18)F]altanserin as a PET radioligand...
  3. ncbi request reprint A complete remote-control system for reliable preparation of [18F]altanserin
    P Z Tan
    VA PET Center, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Appl Radiat Isot 50:923-7. 1999
    ..The preparation took 114 min with 23% yield and high quality...
  4. ncbi request reprint Comparison of [(18)F]altanserin and [(18)F]deuteroaltanserin for PET imaging of serotonin(2A) receptors in baboon brain: pharmacological studies
    J K Staley
    Department of Psychiatry, Yale University School of Medicine and VA Connecticut Healthcare System, 06516, West Haven, CT 06516, USA
    Nucl Med Biol 28:271-9. 2001
    ..These findings suggest that [(18)F]deuteroaltanserin is essentially equivalent to [(18)F]altanserin for 5-HT(2A) receptor imaging in the baboon...
  5. ncbi request reprint Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: preliminary results of a direct comparison in healthy human subjects
    J D Bremner
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Psychiatry Res 91:79-91. 1999
    ..These preliminary findings indicate that PET and SPECT provide comparable results in quantitation of neuroreceptor binding in the human brain...