Daniel B Stetson

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Antiviral defense: interferons and beyond
    Daniel B Stetson
    Howard Hughes Medical Institute, Yale University School of Medicine, CT 06520, USA
    J Exp Med 203:1837-41. 2006
  2. ncbi Type I interferons in host defense
    Daniel B Stetson
    Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Immunity 25:373-81. 2006
  3. ncbi T helper 17 cells get the NOD
    Daniel B Stetson
    Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 27:546-8. 2007
  4. ncbi Trex1 prevents cell-intrinsic initiation of autoimmunity
    Daniel B Stetson
    Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell 134:587-98. 2008
  5. ncbi Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    Daniel B Stetson
    Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Immunity 24:93-103. 2006
  6. ncbi Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo
    Daniel B Stetson
    Howard Hughes Medical Institute, Department of Medicine, University of California, San Francisco, 94143, USA
    Immunity 17:191-200. 2002
  7. ncbi Th2 cells: orchestrating barrier immunity
    Daniel B Stetson
    Howard Hughes Medical Institute, University of California San Francisco, 94143, USA
    Adv Immunol 83:163-89. 2004
  8. ncbi Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo
    Jennifer L Matsuda
    La Jolla Institute for Allergy and Immunology, and Division of Biological Sciences, University of California, San Diego, CA, USA
    Proc Natl Acad Sci U S A 100:8395-400. 2003

Research Grants

  1. Mechanisms and consequences of innate immune recognition of nucleic acids
    Daniel Stetson; Fiscal Year: 2007

Collaborators

Detail Information

Publications8

  1. ncbi Antiviral defense: interferons and beyond
    Daniel B Stetson
    Howard Hughes Medical Institute, Yale University School of Medicine, CT 06520, USA
    J Exp Med 203:1837-41. 2006
    ....
  2. ncbi Type I interferons in host defense
    Daniel B Stetson
    Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Immunity 25:373-81. 2006
    ..These advances highlight the context-specific actions of type I IFNs and clarify the multiple points at which they are integrated into both innate and adaptive immunity...
  3. ncbi T helper 17 cells get the NOD
    Daniel B Stetson
    Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 27:546-8. 2007
    ..In this issue of Immunity, van Beelen et al. (2007) reveal a pathway that elicits potent IL-17 production from memory T cells through activation of the intracellular receptor NOD2...
  4. ncbi Trex1 prevents cell-intrinsic initiation of autoimmunity
    Daniel B Stetson
    Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell 134:587-98. 2008
    ..These findings reveal a cell-intrinsic mechanism for initiation of autoimmunity, implicate the ISD pathway as the cause of AGS, and suggest an unanticipated contribution of endogenous retroelements to autoimmunity...
  5. ncbi Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    Daniel B Stetson
    Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Immunity 24:93-103. 2006
    ..These findings define an innate immune response to DNA linked to type I interferon production...
  6. ncbi Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo
    Daniel B Stetson
    Howard Hughes Medical Institute, Department of Medicine, University of California, San Francisco, 94143, USA
    Immunity 17:191-200. 2002
    ..CD4 subset polarization in this highly characterized model occurs independently from IL-4 expression by naive T cells, which is activated indiscriminately after parasitism...
  7. ncbi Th2 cells: orchestrating barrier immunity
    Daniel B Stetson
    Howard Hughes Medical Institute, University of California San Francisco, 94143, USA
    Adv Immunol 83:163-89. 2004
  8. ncbi Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo
    Jennifer L Matsuda
    La Jolla Institute for Allergy and Immunology, and Division of Biological Sciences, University of California, San Diego, CA, USA
    Proc Natl Acad Sci U S A 100:8395-400. 2003
    ....

Research Grants1

  1. Mechanisms and consequences of innate immune recognition of nucleic acids
    Daniel Stetson; Fiscal Year: 2007
    ..We will also perform experiments with direct relevance to a specific human disease, Aicardi-Goutieres Syndrome (AGS; OMIM 225750). ..