Research Topics
| Stephen C StearnsSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Constraints on the coevolution of contemporary human males and femalesStephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8102, USA
Proc Biol Sci 279:4836-44. 2012..9 ± 15.7°), compared with when they were excluded (87.9 ± 31.6°). We conclude that intralocus sexual conflict constrains the joint evolutionary responses of the two sexes in a contemporary human population...
Evolutionary medicine: its scope, interest and potentialStephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
Proc Biol Sci 279:4305-21. 2012..Because we are on the cusp of so much new research and innovative insights, it is hard to estimate how much impact evolutionary thinking will have on medicine, but it is already clear that its potential is enormous...
Experimental evolution of aging in a bacteriumMartin Ackermann
Institute of Integrative Biology, ETH Zurich, CH 8092 Zurich, Switzerland
BMC Evol Biol 7:126. 2007..We tested the generality of this theory by experimental evolution with Caulobacter crescentus, a bacterium whose asymmetric division allows mother and daughter to be distinguished...
Evolution in health and disease: work in progressS C Stearns
Department of Ecology and Evolutionary Biology, Yale University New Haven, Connecticut 06520 8106, USA
Q Rev Biol 76:417-32. 2001..Currently the most promising areas, those in which experimental rigor can be applied efficiently, include experimental evolution and functional genomics. The pioneers can be proud of what they have set in motion...
Life history evolution: successes, limitations, and prospectsS C Stearns
University of Basel, Zoology Institute, Rheinsprung 9, 4051 Basel, Switzerland
Naturwissenschaften 87:476-86. 2000..They have not yet had as much empirical success, but there are logical reasons to prefer them, and they may soon extend the impact of life history theory into population dynamics and interspecific interactions in coevolving communities...
The naturalist in a world of genomicsStephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8106, USA
Am Nat 161:171-80. 2003..We end with some brief notes about how evolutionary biology and comparative approaches will probably have an impact on functional genomics...
Are we stalled part way through a major evolutionary transition from individual to group?Stephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
Evolution 61:2275-80. 2007
Issues in evolutionary medicineStephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8160, USA
Am J Hum Biol 17:131-40. 2005..A method is suggested to get at the mechanisms of tradeoffs by examining conflicts among functions over gene expression. It could be applied in humans to the tradeoff between reproductive performance and disease resistance...
Measuring selection in contemporary human populationsStephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520 8102, USA
Nat Rev Genet 11:611-22. 2010..We also assemble examples of long-term studies in which additional measurements of evolution could be made. The evidence strongly suggests that we are evolving and that our nature is dynamic, not static...
Colloquium papers: Natural selection in a contemporary human populationSean G Byars
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8102, USA
Proc Natl Acad Sci U S A 107:1787-92. 2010..Selection is tending to lengthen the reproductive period at both ends. To better understand and predict such changes, the design of planned large, long-term, multicohort studies should include input from evolutionary biologists...
Experimental evolution of aging, growth, and reproduction in fruitfliesS C Stearns
Zoology Institute, University of Basel, Rheinsprung 9, CH 4051 Basel, Switzerland
Proc Natl Acad Sci U S A 97:3309-13. 2000....
The experimental evolution of aging in fruitfliesS C Stearns
Zoology Institute, University of Basel, Switzerland
Exp Gerontol 33:785-92. 1998..This is the first clear experimental demonstration of the central claim of the evolutionary theory of aging...
Senescence in a bacterium with asymmetric divisionMartin Ackermann
Division of Molecular Microbiology, Biozentrum, University of Basel, CH-4056 Basel, Switzerland
Science 300:1920. 2003
Progress on canalizationStephen C Stearns
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520-8106, USA
Proc Natl Acad Sci U S A 99:10229-30. 2002
Theoretical biology: safeguards and spursStephen C Stearns
Nature 424:501-4. 2003
Medicine needs evolutionRandolph M Nesse
Science 311:1071. 2006
Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogasterScott D Pletcher
Department of Biology, University College London, The Darwin Building, Gower Street, London WC1E 6BT, UK
Curr Biol 12:712-23. 2002..We used the global patterns of expression profiles to test if particular genomic regions contribute differentially to changes in transcript profiles with age and if global disregulation of gene expression occurs during aging...
