Susan S Spencer

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint When should temporal-lobe epilepsy be treated surgically?
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Lancet Neurol 1:375-82. 2002
  2. ncbi request reprint Initial outcomes in the Multicenter Study of Epilepsy Surgery
    S S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 61:1680-5. 2003
  3. ncbi request reprint Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter study
    S S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 65:912-8. 2005
  4. ncbi request reprint Neural networks in human epilepsy: evidence of and implications for treatment
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Epilepsia 43:219-27. 2002
  5. ncbi request reprint Multiple subpial transection for intractable partial epilepsy: an international meta-analysis
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Epilepsia 43:141-5. 2002
  6. ncbi request reprint Epilepsy: clinical observations and novel mechanisms
    Susan Spencer
    Yale Univeristy School of Medicine, New Haven, CT 06520 8018, USA
    Lancet Neurol 6:14-6. 2007
  7. ncbi request reprint Health-related quality of life over time since resective epilepsy surgery
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Ann Neurol 62:327-34. 2007
  8. doi request reprint Interictal spikes on intracranial recording: behavior, physiology, and implications
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Epilepsia 49:1881-92. 2008
  9. doi request reprint Outcomes of epilepsy surgery in adults and children
    Susan Spencer
    Yale University, School of Medicine, New Haven, CT 06520 8018, USA
    Lancet Neurol 7:525-37. 2008
  10. doi request reprint Background intracranial EEG spectral changes with anti-epileptic drug taper
    Hitten P Zaveri
    Department of Neurology, Yale University, New Haven, CT 06520, USA
    Clin Neurophysiol 121:311-7. 2010

Research Grants

  1. A MULTI-CENTER STUDY OF EPILEPSY SURGERY
    Susan Spencer; Fiscal Year: 2005
  2. MULTICENTER STUDY OF EPILEPSY SURGERY
    Susan Spencer; Fiscal Year: 2000
  3. Anticipating Seizures in Epileptic Networks
    Susan Spencer; Fiscal Year: 2007

Detail Information

Publications63

  1. ncbi request reprint When should temporal-lobe epilepsy be treated surgically?
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Lancet Neurol 1:375-82. 2002
    ....
  2. ncbi request reprint Initial outcomes in the Multicenter Study of Epilepsy Surgery
    S S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 61:1680-5. 2003
    ..To obtain prospective data regarding seizures, anxiety, depression, and quality of life (QOL) outcomes after resective epilepsy surgery...
  3. ncbi request reprint Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter study
    S S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 65:912-8. 2005
    ..In a seven-center prospective observational study of resective epilepsy surgery, the authors examined probability and predictors of entering 2-year remission and the risk of subsequent relapse...
  4. ncbi request reprint Neural networks in human epilepsy: evidence of and implications for treatment
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Epilepsia 43:219-27. 2002
  5. ncbi request reprint Multiple subpial transection for intractable partial epilepsy: an international meta-analysis
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Epilepsia 43:141-5. 2002
    ....
  6. ncbi request reprint Epilepsy: clinical observations and novel mechanisms
    Susan Spencer
    Yale Univeristy School of Medicine, New Haven, CT 06520 8018, USA
    Lancet Neurol 6:14-6. 2007
  7. ncbi request reprint Health-related quality of life over time since resective epilepsy surgery
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Ann Neurol 62:327-34. 2007
    ..Health-related quality of life (HRQOL) improves after resective epilepsy surgery, but data are limited to short follow-up in mostly retrospective reports, with minimal consideration of other potential factors that might influence HRQOL...
  8. doi request reprint Interictal spikes on intracranial recording: behavior, physiology, and implications
    Susan S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Epilepsia 49:1881-92. 2008
    ..We systematically analyzed the frequency, occurrence, and distribution of IISs recorded from multiple intracranial electrodes in 34 refractory epileptic patients with respect to seizures and antiepileptic drug (AED) changes...
  9. doi request reprint Outcomes of epilepsy surgery in adults and children
    Susan Spencer
    Yale University, School of Medicine, New Haven, CT 06520 8018, USA
    Lancet Neurol 7:525-37. 2008
    ..In this Review, we consider the outcomes of surgery in adults and children with epilepsy and review studies of neurological and cognitive sequelae, psychiatric and behavioural outcomes, and overall health-related quality of life...
  10. doi request reprint Background intracranial EEG spectral changes with anti-epileptic drug taper
    Hitten P Zaveri
    Department of Neurology, Yale University, New Haven, CT 06520, USA
    Clin Neurophysiol 121:311-7. 2010
    ..Here, we expand the measures evaluated to icEEG power and frequency band power...
  11. doi request reprint Localization-related epilepsy exhibits significant connectivity away from the seizure-onset area
    Hitten P Zaveri
    Departments of Neurology, Yale University, New Haven, CT 06520, USA
    Neuroreport 20:891-5. 2009
    ..We show significant nonzero connectivity not only for the seizure-onset area but also several centimeters from it, for example, for the beta-frequency band (P<10(-5)), suggesting a nonlocal character to this disorder...
  12. doi request reprint Spatial distribution of intracranially recorded spikes in medial and lateral temporal epilepsies
    Irina I Goncharova
    Departments of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA
    Epilepsia 50:2575-85. 2009
    ..To test this hypothesis, we studied the spatial distribution of intracranially recorded interictal spikes in patients with medial temporal (MT) and lateral temporal (LT) neocortical seizure onset...
  13. doi request reprint A decrease in EEG energy accompanies anti-epileptic drug taper during intracranial monitoring
    Hitten P Zaveri
    Department of Neurology, Yale University, 333 Cedar Street, New Haven, CT 06520, USA
    Epilepsy Res 86:153-62. 2009
    ..We measured change in signal energy of icEEGs in response to AED taper to quantify changes in excitation which accompany the increased propensity for seizures...
  14. pmc Suicide outcomes after resective epilepsy surgery
    Hamada Hamid
    Yale University School of Medicine, New Haven, CT, USA
    Epilepsy Behav 20:462-4. 2011
    ..Two of the patients reported moderate to severe anxiety symptoms (BAI=17 and 21, respectively). Suicide may occur after epilepsy surgery, even when patients report excellent seizure control...
  15. ncbi request reprint Localizing value of ictal-interictal SPECT analyzed by SPM (ISAS)
    Kelly A McNally
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Epilepsia 46:1450-64. 2005
    ..A widely available and objective method is needed to interpret ambiguous ictal and postictal scans, with changes in multiple brain regions...
  16. doi request reprint Intracranially recorded interictal spikes: relation to seizure onset area and effect of medication and time of day
    Irina I Goncharova
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA Electronic address
    Clin Neurophysiol 124:2119-28. 2013
    ..The relationship between seizures and interictal spikes remains undetermined. We analyzed intracranial EEG (icEEG) recordings to examine the relationship between the seizure onset area and interictal spikes...
  17. ncbi request reprint Positive and negative network correlations in temporal lobe epilepsy
    Hal Blumenfeld
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8018, USA
    Cereb Cortex 14:892-902. 2004
    ..These results suggest that impaired consciousness in temporal lobe seizures may result from focal abnormal activity in temporal and subcortical networks linked to widespread impaired function of the association cortex...
  18. ncbi request reprint GAT1 and GAT3 expression are differently localized in the human epileptogenic hippocampus
    Tih Shih Lee
    Department of Psychiatry, Yale University School of Medicine, Park Street, New Haven, CT 06520, USA
    Acta Neuropathol 111:351-63. 2006
    ....
  19. ncbi request reprint Hypothalamic hamartomas: seven cases and review of the literature
    Dang Nguyen
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Epilepsy Behav 4:246-58. 2003
    ..Gamma knife surgery may be especially useful for small sessile lesions, failed partial resections, or patients not appropriate or refusing open surgery...
  20. pmc Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes
    Tih Shih Lee
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520 8082, USA
    Mol Med 13:1-13. 2007
    ..Such glutamate release may excite surrounding neurons and elicit seizure activity...
  21. ncbi request reprint Temporal lobe tumoral epilepsy: characteristics and predictors of surgical outcome
    Megdad M Zaatreh
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 61:636-41. 2003
    ..To review the clinical and neurophysiologic features and surgical outcome in patients with intractable temporal lobe tumoral epilepsy...
  22. doi request reprint Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients
    Idil Cavus
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Epilepsia 49:1358-66. 2008
    ..Temporal lobe epilepsy (TLE) is associated with smaller hippocampal volume and with elevated extracellular (EC) glutamate levels. We investigated the relationship between the hippocampal volume and glutamate in refractory TLE patients...
  23. doi request reprint Temporal distributions of seizure occurrence from various epileptogenic regions
    T S Durazzo
    Department of Neurology, Yale University, New Haven, CT 06520, USA
    Neurology 70:1265-71. 2008
    ..For these ends, we determined and analyzed detailed temporal distributions of seizures arising from the frontal, parietal, occipital, neocortical temporal, and mesial temporal lobes...
  24. doi request reprint Influence of anxiety on memory performance in temporal lobe epilepsy
    Franklin C Brown
    Department of Neurology, Yale University, New Haven, CT, USA Electronic address
    Epilepsy Behav 31:19-24. 2014
    ..This study adds to the existing literature which suggests that drawing-based visual memory tests do not lateralize among patients with TLE, regardless of anxiety levels. ..
  25. ncbi request reprint Selective frontal, parietal, and temporal networks in generalized seizures
    Hal Blumenfeld
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Neuroimage 19:1556-66. 2003
    ..Relative sparing of many brain regions during both spontaneous and induced seizures suggests that specific networks may be more important than others in so-called generalized seizures...
  26. ncbi request reprint Levetiracetam efficacy in refractory partial-onset seizures, especially after failed epilepsy surgery
    Mahmood Motamedi
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520, U S A
    Epilepsia 44:211-4. 2003
    ..We conducted a retrospective study to evaluate the efficacy of levetiracetam as adjunctive therapy in patients with localization-related epilepsy, and specifically in the subset of patients for whom epilepsy surgery failed...
  27. ncbi request reprint A retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: evidence for distinctive patient subcategories
    Nihal C de Lanerolle
    Department of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8082, U S A
    Epilepsia 44:677-87. 2003
    ..We attempted to relate neuronal density, immunohistochemistry, electrophysiologic data, and surgical outcome...
  28. pmc Racial differences in patient expectations prior to resective epilepsy surgery
    Christine Bower Baca
    Department of Neurology, University of California at Los Angeles, 911 Broxton Avenue, Los Angeles, CA 90024, USA
    Epilepsy Behav 15:452-5. 2009
    ..Elucidating the reason for these differences can aid in the clinical decision-making process for resective surgery and potentially address disparities in its utilization...
  29. ncbi request reprint Health care costs decline after successful epilepsy surgery
    J T Langfitt
    Department of Neurology, University of Rochester, Rochester, NY 14642, USA
    Neurology 68:1290-8. 2007
    ..There is little information about how health care costs are affected by evaluation and surgery...
  30. ncbi request reprint On the use of bipolar montages for time-series analysis of intracranial electroencephalograms
    Hitten P Zaveri
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
    Clin Neurophysiol 117:2102-8. 2006
    ....
  31. ncbi request reprint Recent advances in the treatment of epilepsy
    Dang K Nguyen
    Department of Neurology, Yale School of Medicine, New Haven, CT 06520, USA
    Arch Neurol 60:929-35. 2003
  32. pmc Effects of working memory load on oscillatory power in human intracranial EEG
    Jed A Meltzer
    Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA
    Cereb Cortex 18:1843-55. 2008
    ....
  33. pmc Impaired consciousness in temporal lobe seizures: role of cortical slow activity
    Dario J Englot
    Department of Neurosurgery, University of California, San Francisco, CA 94122, USA
    Brain 133:3764-77. 2010
    ..Further investigations will be needed to fully determine the role of cortical-subcortical networks in ictal neocortical dysfunction and may reveal treatments to prevent this important negative consequence of temporal lobe epilepsy...
  34. ncbi request reprint MR characteristics of neoplasms and vascular malformations associated with epilepsy
    R A Bronen
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Magn Reson Imaging 13:1153-62. 1995
    ..The temporal lobe location, cortical involvement, and calvarial remodelling are findings typical of NVL. MR characteristics can successfully predict the pathologic substrate of these lesions...
  35. ncbi request reprint Multiple subpial transections: the Yale experience
    L P Mulligan
    Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520
    Epilepsia 42:226-9. 2001
    ..CONCLUSIONS: In selected patients, MST may be a viable alternative when the epileptogenic focus lies in unresectable cortex. A multicenter study with appreciable patient numbers will be necessary to define predictive factors for success...
  36. ncbi request reprint Economic impact of replacing CT with MR imaging for refractory epilepsy
    R A Bronen
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Magn Reson Imaging 15:857-62. 1997
    ..To evaluate the economic costs of using computed tomography (CT) vs. magnetic resonance (MR) imaging in the preoperative evaluation of refractory epilepsy patients...
  37. pmc Intracranial EEG power and metabolism in human epilepsy
    J W Pan
    Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA
    Epilepsy Res 87:18-24. 2009
    ..These data are also consistent with the hypothesis that high frequency activity is an abnormal manifestation of tissue injury...
  38. ncbi request reprint Ratio-images calculated from interictal positron emission tomography and single-photon emission computed tomography for quantification of the uncoupling of brain metabolism and perfusion in epilepsy
    I G Zubal
    Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, Connecticut, USA
    Epilepsia 41:1560-6. 2000
    ..Uncoupling of these two functions has been demonstrated to be a characteristic of epileptogenic tissue in temporal lobe epilepsy and has the potential to serve as a diagnostic measure for localization in other areas as well...
  39. pmc Expectations prior to epilepsy surgery: an exploratory comparison of men and women
    C M Bower
    Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA
    Seizure 18:228-31. 2009
    ..05). Exploratory factor analysis indicated a different pattern of associations among the 12 importance items for men and women. Whether gender differences in presurgical values are associated with outcomes needs exploration...
  40. pmc Clinical use of ictal SPECT in secondarily generalized tonic-clonic seizures
    G I Varghese
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Brain 132:2102-13. 2009
    ..These findings suggest that, with appropriate cautious interpretation, ictal SPECT in secondarily generalized seizures can help localize the region of seizure onset...
  41. pmc Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures
    H Blumenfeld
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8018, USA
    Brain 132:999-1012. 2009
    ..Understanding the networks involved in generalized tonic-clonic seizures can provide insights into mechanisms of behavioural changes, and may elucidate targets for improved therapies...
  42. ncbi request reprint Distinguishing subtypes of temporal lobe epilepsy with background hippocampal activity
    H P Zaveri
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, U S A
    Epilepsia 42:725-30. 2001
    ..This report describes a retrospective study to investigate the feasibility of doing so during intracranial monitoring...
  43. ncbi request reprint Measuring the coherence of intracranial electroencephalograms
    H P Zaveri
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
    Clin Neurophysiol 110:1717-25. 1999
    ..The performance characteristics of the coherence estimator and statistical testing of coherence estimates are described in this manuscript...
  44. ncbi request reprint Clinical applications: MRI, SPECT, and PET
    S S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
    Magn Reson Imaging 13:1119-24. 1995
    ..Preliminary evidence also indicates that the distribution of hyperperfusion on ictal SPECT can differentiate subtypes of TLE. Combining the results of refined imaging techniques holds great promise in epilepsy localization and diagnosis...
  45. ncbi request reprint The effect of a scalp reference signal on coherence measurements of intracranial electroencephalograms
    H P Zaveri
    Department of Neurology, Yale University School of Medicine, CT 06520, New Haven, USA
    Clin Neurophysiol 111:1293-9. 2000
    ..To determine the effect of a scalp reference signal, such as that recorded from the mastoid or ear, on the coherence of referential intracranial electroencephalograms (EEGs)...
  46. ncbi request reprint Ictal neocortical slowing in temporal lobe epilepsy
    H Blumenfeld
    Department of Neurology and Neurobiology, Yale University School of Medicine, New Haven, CT, USA
    Neurology 63:1015-21. 2004
    ..Temporal lobe epilepsy (TLE) may affect brain regions outside the temporal lobe, causing impaired neocortical function during seizures...
  47. ncbi request reprint Interictal 99mTc-HMPAO SPECT in temporal lobe epilepsy: relation to clinical variables
    R A Avery
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520-8018, USA
    Epilepsia 42:869-74. 2001
    ..CONCLUSIONS: Significant correlation of age at onset and duration of epilepsy with AIs in RTLE but not LTLE suggests physiologic processes may be determined in part by laterality of TLE. Clinical applications are problematic...
  48. ncbi request reprint Frontal lobe tumoral epilepsy: clinical, neurophysiologic features and predictors of surgical outcome
    Megdad M Zaatreh
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Epilepsia 43:727-33. 2002
    ..To review the clinical, neurophysiologic features and surgical outcomes in patients with frontal lobe tumors and chronic intractable seizures...
  49. ncbi request reprint Long-term seizure outcome in patients initially seizure-free after resective epilepsy surgery
    H H Yoon
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 61:445-50. 2003
    ..To evaluate the likelihood of and risk factors for seizure recurrence in patients initially seizure-free after resective surgery for intractable epilepsy...
  50. ncbi request reprint Worsening of quality of life after epilepsy surgery: effect of seizures and memory decline
    J T Langfitt
    Department of Neurology, University of Rochester, Rochester, NY 14642, USA
    Neurology 68:1988-94. 2007
    ..The relative impact of these unfavorable outcomes on HRQOL has not been described...
  51. pmc Visual memory in patients after anterior right temporal lobectomy and adult normative data for the Brown Location Test
    Franklin C Brown
    Department of Neurosurgery, Yale University, School of Medicine, New Haven, CT, USA
    Epilepsy Behav 17:215-20. 2010
    ..The present findings support a role for the right anterior mesial temporal lobe in dot location learning and memory...
  52. ncbi request reprint Surgical management of parietal lobe epilepsy
    Hahnah J Kasowski
    Department of Neurosurgery, Yale University, New Haven, Connecticut, USA
    Adv Neurol 93:347-56. 2003
    ..Therefore, one must consider cortical plasticity and functional redistribution as possible reasons for this, particularly when most of these substrates are of developmental origin...
  53. ncbi request reprint Comparison of statistical parametric mapping and SPECT difference imaging in patients with temporal lobe epilepsy
    David J Chang
    Section of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06501, USA
    Epilepsia 43:68-74. 2002
    ....
  54. ncbi request reprint The multicenter study of epilepsy surgery: recruitment and selection for surgery
    Anne T Berg
    BIOS NIU, DeKalb, Illinois 60115, USA
    Epilepsia 44:1425-33. 2003
    ..Such information is necessary for providing the epidemiologic and clinical context in which epilepsy surgery is currently performed in the United States and in other developed countries...
  55. ncbi request reprint Interrater reliability among epilepsy centers: multicenter study of epilepsy surgery
    Sheryl R Haut
    Comprehensive Epilepsy Management Center and Departments of Neurology and Pediatrics of the Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York, USA
    Epilepsia 43:1396-401. 2002
    ..To measure the interrater reliability of presurgical testing and surgical decisions among epilepsy centers...
  56. ncbi request reprint Reduction of AEDs in postsurgical patients who attain remission
    Anne T Berg
    BIOS, NIU, DeKalb, Illinois 60115, USA
    Epilepsia 47:64-71. 2006
    ..Little evidence guides practice regarding the reduction of antiepileptic drugs (AEDs) in individuals who achieve significant periods of remission after resective surgery...
  57. ncbi request reprint Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy
    Gauri H Malthankar-Phatak
    Department of Pharmaceutical Sciences, College of Pharmacy, Idaho State University, Pocatello, Idaho 83209, USA
    Epilepsia 47:1292-9. 2006
    ....
  58. ncbi request reprint Epilepsy in North America: a report prepared under the auspices of the global campaign against epilepsy, the International Bureau for Epilepsy, the International League Against Epilepsy, and the World Health Organization
    William H Theodore
    National Institutes of Health, Bethesda, Maryland 20892, USA
    Epilepsia 47:1700-22. 2006
    ....
  59. pmc Stopping antiepileptic drugs after epilepsy surgery: a survey of U.S. epilepsy center neurologists
    Anne T Berg
    Department of Biology, Northern Illinois University, DeKalb, IL, USA
    Epilepsy Behav 10:219-22. 2007
    ..g., focal pathology in favor of and persistent auras against stopping antiepileptic drugs), it is unclear how well these factors determine seizure outcome in this setting...
  60. ncbi request reprint Gamma knife radiosurgery for refractory medial temporal lobe epilepsy: too little, too late?
    Susan S Spencer
    Neurology 70:1654-5. 2008
  61. ncbi request reprint An approach to the evaluation of a patient for seizures and epilepsy
    S Nizam Ahmed
    Comprehensive Adult Epilepsy Program, University of Alberta, Edmonton, Alberta T6G 2B7, Canada
    WMJ 103:49-55. 2004
    ..This article provides directions and guidelines both for the family practice physician and the specialist in evaluating this patient population in the clinics...
  62. doi request reprint Local spatial effect of 50 Hz cortical stimulation in humans
    Ryder P Gwinn
    Epilepsy Center, Seattle Neuroscience Institute, Seattle, Washington, USA
    Epilepsia 49:1602-10. 2008
    ..To help characterize this effect, we analyzed electrocorticography (ECoG) recorded adjacent to stimulated contacts during and after bipolar stimulation in patients undergoing functional cortical mapping with subdural electrodes...
  63. ncbi request reprint Employment outcomes following resective epilepsy surgery
    Peter S Chin
    Robert Wood Johnson Clinical Scholars Program, Department of Medicine, University of California Los Angeles and the Greater Los Angeles VA Health Care System, Los Angeles, California 90095 1769, USA
    Epilepsia 48:2253-7. 2007
    ..Analyze determinates of employment changes from before to 2 years after surgery in refractory focal epilepsy patients...

Research Grants16

  1. A MULTI-CENTER STUDY OF EPILEPSY SURGERY
    Susan Spencer; Fiscal Year: 2005
    ....
  2. MULTICENTER STUDY OF EPILEPSY SURGERY
    Susan Spencer; Fiscal Year: 2000
    ....
  3. Anticipating Seizures in Epileptic Networks
    Susan Spencer; Fiscal Year: 2007
    ..Fifteen patients will be studied in the retrospective studies, and 45 patients will be studied in the prospective studies. ..