L R Solomon

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment
    Lawrence R Solomon
    Section of Hematology, Department of Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, United Kingdom
    Blood Rev 21:113-30. 2007
  2. pmc Diabetes as a cause of clinically significant functional cobalamin deficiency
    Lawrence R Solomon
    Section of Palliative Care, Department of Medicine, Yale University School ofMedicine, New Haven, Connecticut, USA
    Diabetes Care 34:1077-80. 2011
  3. doi request reprint Advanced age as a risk factor for folate-associated functional cobalamin deficiency
    Lawrence R Solomon
    Section of Palliative Care, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut
    J Am Geriatr Soc 61:577-82. 2013
  4. ncbi request reprint Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testing
    Lawrence R Solomon
    Department of Medicine, Yale University Health Services, 17 Hillhouse Ave, P O Box 208237, New Haven, CT 06520 8237, USA
    Blood 105:978-85; author reply 1137. 2005
  5. ncbi request reprint Oral pharmacologic doses of cobalamin may not be as effective as parenteral cobalamin therapy in reversing hyperhomocystinemia and methylmalonic acidemia in apparently normal subjects
    L R Solomon
    Department of Internal Medicine, Section of Hematology, Yale University School of Medicine, New Haven, CT 06520 8021, USA
    Clin Lab Haematol 28:275-8. 2006
  6. ncbi request reprint Treatment and prevention of pain due to vaso-occlusive crises in adults with sickle cell disease: an educational void
    Lawrence R Solomon
    Adult Sickle Cell Disease Program, Section of Hematology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8021, USA
    Blood 111:997-1003. 2008
  7. ncbi request reprint Pain management in adults with sickle cell disease in a medical center emergency department
    Lawrence R Solomon
    Adult Sickle Cell Disease Program, Sections of Hematology and Palliative Care, Department of Medicine, Yale University School of Medicine, 333 Cedar St, PO Box 208201, New Haven, CT 06520 8021, USA
    J Natl Med Assoc 102:1025-32. 2010
  8. ncbi request reprint Oral vitamin B12 therapy: a cautionary note
    Lawrence R Solomon
    Blood 103:2863. 2004
  9. ncbi request reprint Is testing for clinical cobalamin deficiency truly unreliable?
    Ralph Carmel
    Blood 106:1136-8; author reply 1137-8. 2005

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment
    Lawrence R Solomon
    Section of Hematology, Department of Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, United Kingdom
    Blood Rev 21:113-30. 2007
    ..While oral cobalamin immediate-release is adequate for many patients, its effectiveness in reversing neurologic abnormalities has yet to be established...
  2. pmc Diabetes as a cause of clinically significant functional cobalamin deficiency
    Lawrence R Solomon
    Section of Palliative Care, Department of Medicine, Yale University School ofMedicine, New Haven, Connecticut, USA
    Diabetes Care 34:1077-80. 2011
    ..Because diabetes is also common in the elderly and diabetic neuropathy resembles that of Cbl deficiency, the role of diabetes in functional Cbl deficiency was explored...
  3. doi request reprint Advanced age as a risk factor for folate-associated functional cobalamin deficiency
    Lawrence R Solomon
    Section of Palliative Care, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut
    J Am Geriatr Soc 61:577-82. 2013
    ..To determine whether high serum folate levels contribute to metabolite changes in elderly subjects with normal cobalamin levels...
  4. ncbi request reprint Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testing
    Lawrence R Solomon
    Department of Medicine, Yale University Health Services, 17 Hillhouse Ave, P O Box 208237, New Haven, CT 06520 8237, USA
    Blood 105:978-85; author reply 1137. 2005
    ..It is concluded that Cbl, MMA, and HCys levels fluctuate with time and neither predict nor preclude the presence of Cbl-responsive hematologic or neurologic disorders...
  5. ncbi request reprint Oral pharmacologic doses of cobalamin may not be as effective as parenteral cobalamin therapy in reversing hyperhomocystinemia and methylmalonic acidemia in apparently normal subjects
    L R Solomon
    Department of Internal Medicine, Section of Hematology, Yale University School of Medicine, New Haven, CT 06520 8021, USA
    Clin Lab Haematol 28:275-8. 2006
    ..However, intramuscular cobalamin promptly decreased both metabolites to normal. Thus, parenteral cobalamin therapy may have greater metabolic effects than oral vitamin therapy even in apparently normal subjects...
  6. ncbi request reprint Treatment and prevention of pain due to vaso-occlusive crises in adults with sickle cell disease: an educational void
    Lawrence R Solomon
    Adult Sickle Cell Disease Program, Section of Hematology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8021, USA
    Blood 111:997-1003. 2008
    ..Thus, research and training on pain control in sickle cell disease are needed to parallel studies of environmental and genetic factors contributing to the known clinical heterogeneity of this disorder...
  7. ncbi request reprint Pain management in adults with sickle cell disease in a medical center emergency department
    Lawrence R Solomon
    Adult Sickle Cell Disease Program, Sections of Hematology and Palliative Care, Department of Medicine, Yale University School of Medicine, 333 Cedar St, PO Box 208201, New Haven, CT 06520 8021, USA
    J Natl Med Assoc 102:1025-32. 2010
    ....
  8. ncbi request reprint Oral vitamin B12 therapy: a cautionary note
    Lawrence R Solomon
    Blood 103:2863. 2004
  9. ncbi request reprint Is testing for clinical cobalamin deficiency truly unreliable?
    Ralph Carmel
    Blood 106:1136-8; author reply 1137-8. 2005