Research Topics
| Stephen A SmithSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Bioactive endophytes warrant intensified exploration and conservationStephen A Smith
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America
PLoS ONE 3:e3052. 2008..Here we provide direct evidence from bioassays of endophytes isolated from tropical plants and bioinformatic analyses that novel biology will indeed yield novel chemistry of potential value...
Phyutility: a phyloinformatics tool for trees, alignments and molecular dataStephen A Smith
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
Bioinformatics 24:715-6. 2008..AVAILABILITY: Phyutility, including source code, documentation, examples, and executables, is available at http://code.google.com/p/phyutility...
Rates of molecular evolution are linked to life history in flowering plantsStephen A Smith
Department of Ecology and Evolutionary Biology, 21 Sachem Street, Post Office Box 208105, Yale University, New Haven, CT 06520 8105, USA
Science 322:86-9. 2008....
The origins of C4 grasslands: integrating evolutionary and ecosystem scienceErika J Edwards
Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA
Science 328:587-91. 2010....
Combining historical biogeography with niche modeling in the Caprifolium clade of Lonicera (Caprifoliaceae, Dipsacales)Stephen A Smith
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
Syst Biol 59:322-41. 2010..These results suggest a possible model for the origin of the Madrean-Tethyan disjunction pattern...
Climate, niche evolution, and diversification of the "bird-cage" evening primroses (Oenothera, sections Anogra and Kleinia)Margaret E K Evans
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06511, USA
Am Nat 173:225-40. 2009..Our data are also consistent with Axelrod's hypothesis that the spread of arid conditions in western North America stimulated diversification of arid-adapted lineages...
Understanding angiosperm diversification using small and large phylogenetic treesStephen A Smith
Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
Am J Bot 98:404-14. 2011..Mega-phylogenetic studies of diversification hold great promise for revealing new patterns, but we will need to focus more attention on properly specifying null expectation...
Resolving the evolutionary relationships of molluscs with phylogenomic toolsStephen A Smith
Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
Nature 480:364-7. 2011..This well-resolved tree will constitute a framework for further studies of mollusc evolution, development and anatomy...
Patterns in the assembly of temperate forests around the Northern HemisphereMichael J Donoghue
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
Philos Trans R Soc Lond B Biol Sci 359:1633-44. 2004..Fortunately, many more plant groups show relevant disjunction patterns and could soon be added to such analyses...
Phylogenetic analyses reveal the shady history of C4 grassesErika J Edwards
Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA
Proc Natl Acad Sci U S A 107:2532-7. 2010..Furthermore, we argue that the evolution of cold tolerance in certain C(3) lineages is an overlooked innovation that has profoundly influenced the patterning of grassland communities across the globe...
Increasing data transparency and estimating phylogenetic uncertainty in supertrees: Approaches using nonparametric bootstrappingBrian R Moore
Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
Syst Biol 55:662-76. 2006..These methods have been implemented in the freely available program, tREeBOOT...
Differential gene expression in the siphonophore Nanomia bijuga (Cnidaria) assessed with multiple next-generation sequencing workflowsStefan Siebert
Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island, United States of America
PLoS ONE 6:e22953. 2011..Third, the impacts of partial reference sequences on the ability to detect DE can be mitigated through workflow choice and deeper reference sequencing...
Broad phylogenomic sampling improves resolution of the animal tree of lifeCasey W Dunn
Kewalo Marine Laboratory, PBRC, University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
Nature 452:745-9. 2008..Many relationships between a stable subset of taxa find strong support, and a diminishing number of lineages remain recalcitrant to placement on the tree...
Maximum likelihood inference of geographic range evolution by dispersal, local extinction, and cladogenesisRichard H Ree
Department of Botany, Field Museum of Natural History, Chicago, Illinois 60605, USA
Syst Biol 57:4-14. 2008..The DEC model is thus an incremental advance that highlights considerable potential in the nascent field of model-based historical biogeographic inference...
Amphibian resources on the internetMichael W Nolan
Department of Biomedical Sciences and Pathobiology, VMRCVM, Virginia Polytechnic Institute and State University, Duck Pond Drive, Blacksburg, VA 24061 0442, USA
ILAR J 48:290-6. 2007..For each web site, descriptive titles, web addresses, and a brief review are provided. Note that the authors of this review cannot assure the accuracy of content in these web resources...
Expression and functional activity of PPARgamma in pancreatic beta cellsHannah J Welters
Institute of Biomedical and Clinical Science, Peninsula Medical School, Plymouth, Devon, UK
Br J Pharmacol 142:1162-70. 2004..Taken together, the present data suggest that, at least under in vitro conditions, thiazolidinediones do not exert direct protective effects against fatty acid-mediated cytotoxicity in pancreatic beta cells...
A recombinant vaccine expressing a mammalian Mycobacterium sp. antigen is immunostimulatory but not protective in striped bassDavid J Pasnik
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine (VMRCVM, Virginia Polytechnic Institute and State University (VPI and SU, Duck Pond Drive, Blacksburg, VA 24061, USA
Vet Immunol Immunopathol 95:43-52. 2003..However, survival studies determined that inoculated fish failed to demonstrate cross-protective responses after live Mycobacterium marinum challenge 70 days post-inoculation...
