V I Slepnev

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Accessory factors in clathrin-dependent synaptic vesicle endocytosis
    V I Slepnev
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, 295 Congress Avenue, New Haven, Connecticut 06510, USA
    Nat Rev Neurosci 1:161-72. 2000
  2. ncbi The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module
    J A Rosenthal
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 274:33959-65. 1999
  3. ncbi The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals
    H Chen
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven Connecticut 06510, USA
    J Biol Chem 274:3257-60. 1999
  4. ncbi Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites
    V I Slepnev
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 275:17583-9. 2000
  5. ncbi Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
    H Chen
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Nature 394:793-7. 1998
  6. ncbi Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2
    S R Floyd
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 276:8104-10. 2001
  7. ncbi Role of phosphorylation in regulation of the assembly of endocytic coat complexes
    V I Slepnev
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06510, USA
    Science 281:821-4. 1998

Collaborators

  • H Chen
  • L Pellegrini
  • S R Floyd
  • P De Camilli
  • J A Rosenthal
  • L H Tsai
  • E B Porro
  • G C Ochoa
  • A E Salcini
  • P P Di Fiore

Detail Information

Publications7

  1. ncbi Accessory factors in clathrin-dependent synaptic vesicle endocytosis
    V I Slepnev
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, 295 Congress Avenue, New Haven, Connecticut 06510, USA
    Nat Rev Neurosci 1:161-72. 2000
    ..This review summarizes these advances with a special focus on accessory factors and highlights new aspects of clathrin-mediated endocytosis revealed by the study of these factors...
  2. ncbi The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module
    J A Rosenthal
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 274:33959-65. 1999
    ..High overexpression of green fluorescent protein-epsin 2 mislocalizes components of the clathrin coat and inhibits clathrin-mediated endocytosis. The epsins define a new protein family implicated in membrane dynamics at the cell surface...
  3. ncbi The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals
    H Chen
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven Connecticut 06510, USA
    J Biol Chem 274:3257-60. 1999
    ....
  4. ncbi Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites
    V I Slepnev
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 275:17583-9. 2000
    ....
  5. ncbi Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
    H Chen
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Nature 394:793-7. 1998
    ..We propose that epsin may participate, together with Eps15, in the molecular rearrangement of the clathrin coats that are required for coated-pit invagination and vesicle fission...
  6. ncbi Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2
    S R Floyd
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 276:8104-10. 2001
    ....
  7. ncbi Role of phosphorylation in regulation of the assembly of endocytic coat complexes
    V I Slepnev
    Howard Hughes Medical Institute and Department of Cell Biology, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06510, USA
    Science 281:821-4. 1998
    ..Thus, phosphorylation regulates the association and dissociation cycle of the clathrin-based endocytic machinery, and calcium-dependent dephosphorylation of endocytic proteins could prepare nerve terminals for a burst of endocytosis...