ALBERT SHAW

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi request reprint Aging of the innate immune system
    Albert C Shaw
    Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 300 Cedar St Box 208022, New Haven, CT 06520, USA
    Curr Opin Immunol 22:507-13. 2010
  2. pmc Dysregulation of human Toll-like receptor function in aging
    Albert C Shaw
    Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Ageing Res Rev 10:346-53. 2011
  3. pmc Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults
    Dana W Dunne
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 5:e11343. 2010

Research Grants

Detail Information

Publications3

  1. doi request reprint Aging of the innate immune system
    Albert C Shaw
    Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 300 Cedar St Box 208022, New Haven, CT 06520, USA
    Curr Opin Immunol 22:507-13. 2010
    ..Thus, immunosenescence in the innate immune system appears to reflect dysregulation, rather than exclusively impaired function...
  2. pmc Dysregulation of human Toll-like receptor function in aging
    Albert C Shaw
    Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Ageing Res Rev 10:346-53. 2011
    ..These findings are consistent with an overarching theme of age-associated dysregulation of TLR signaling that likely contributes to the increased morbidity and mortality from infectious diseases found in geriatric patients...
  3. pmc Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults
    Dana W Dunne
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 5:e11343. 2010
    ..We studied monocyte Toll-like receptor (TLR) expression and cytokine production in 137 patients with autoimmune diseases who were maintained on immunosuppressive medications and 419 non-immunosuppressed individuals...

Research Grants6

  1. SIGNAL TRANSDUCTION PATHWAYS IN EARLY B CELL DEVELOPMENT
    ALBERT SHAW; Fiscal Year: 2002
    ..These experiments should have implications not only for B cell development, but also for the understanding of immunodeficiency syndromes and lymphoid malignancies. ..
  2. Top3 Homologues in Lymphocyte Genome Stability and Aging
    ALBERT SHAW; Fiscal Year: 2009
    ..abstract_text> ..