Research TopicsSpecies | ALBERT SHAWSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Aging of the innate immune systemAlbert C Shaw
Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 300 Cedar St Box 208022, New Haven, CT 06520, USA
Curr Opin Immunol 22:507-13. 2010..Thus, immunosenescence in the innate immune system appears to reflect dysregulation, rather than exclusively impaired function...
Dysregulation of human Toll-like receptor function in agingAlbert C Shaw
Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
Ageing Res Rev 10:346-53. 2011..These findings are consistent with an overarching theme of age-associated dysregulation of TLR signaling that likely contributes to the increased morbidity and mortality from infectious diseases found in geriatric patients...
Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adultsDana W Dunne
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
PLoS ONE 5:e11343. 2010..We studied monocyte Toll-like receptor (TLR) expression and cytokine production in 137 patients with autoimmune diseases who were maintained on immunosuppressive medications and 419 non-immunosuppressed individuals...
Research Grants
- SIGNAL TRANSDUCTION PATHWAYS IN EARLY B CELL DEVELOPMENTALBERT SHAW; Fiscal Year: 2002..These experiments should have implications not only for B cell development, but also for the understanding of immunodeficiency syndromes and lymphoid malignancies. ..
- Top3 Homologues in Lymphocyte Genome Stability and AgingALBERT SHAW; Fiscal Year: 2009..abstract_text> ..
