D W Self
Affiliation: Yale University
- Relapse to drug-seeking: neural and molecular mechanismsD W Self
Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Drug Alcohol Depend 51:49-60. 1998..A detailed understanding of the neural and molecular basis of relapse will facilitate efforts to develop truly effective treatments and preventive measures...
- Neural substrates of drug craving and relapse in drug addictionD W Self
Division of Molecular Psychiatry, Center for Genes and Behavior, Yale University School of Medicine and Connecticut Mental Health Center, New Haven 06508, USA
Ann Med 30:379-89. 1998..These findings identify D1 and D2-dopamine receptor mechanisms as potential targets for developing anticraving compounds to treat drug addiction...
- Effects of the novel D1 dopamine receptor agonist ABT-431 on cocaine self-administration and reinstatementD W Self
Divison of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA
Ann N Y Acad Sci 909:133-44. 2000..The profile of ABT-431 is similar to the behavioral effects of other structurally distinct D1 agonists, and is consistent with the desired profile of a "methadone-like" compounds for cocaine addiction...
- Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administrationE F Schmidt
Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Yale University School of Medicine, New Haven, Connecticut 06508, USA
J Neurosci 21:RC137. 2001..The ability of extinction training to restore NAc TH levels is hypothesized to accelerate recovery from dopamine depletion and anhedonia during cocaine withdrawal...