LARRY D SCAHILL

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Methylphenidate: mechanism of action and clinical update
    Lawrence Scahill
    Yale University, New Haven, CT, USA
    J Child Adolesc Psychiatr Nurs 17:85-6. 2004
  2. ncbi request reprint Sudden death in a patient with Tourette syndrome during a clinical trial of ziprasidone
    Lawrence Scahill
    Child Study Center, School of Medicine and School of Nursing, Yale University, New Haven, CT 06520, USA
    J Psychopharmacol 19:205-6. 2005
  3. doi request reprint Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems
    Lawrence Scahill
    Child Study Center, New Haven, CT 06520, USA
    J Am Acad Child Adolesc Psychiatry 51:136-46. 2012
  4. doi request reprint Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders
    Lawrence Scahill
    Yale University School of Nursing and Child Study Center, 230 S Frontage Rd, New Haven, CT, USA
    J Autism Dev Disord 42:432-40. 2012
  5. ncbi request reprint Psychosocial and clinical correlates of ADHD in a community sample of school-age children
    L Scahill
    Yale Child Study Center, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 38:976-84. 1999
  6. ncbi request reprint Randomized trial of parent management training in children with tic disorders and disruptive behavior
    Lawrence Scahill
    Yale Child Study Center, New Haven, CT 06520 7900, USA
    J Child Neurol 21:650-6. 2006
  7. ncbi request reprint Influence of age and tic disorders on obsessive-compulsive disorder in a pediatric sample
    Larry Scahill
    Yale Child Study Center, and Yale School of Nursing, New Haven, Connecticut 06520, USA
    J Child Adolesc Psychopharmacol 13:S7-17. 2003
  8. ncbi request reprint Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders
    Lawrence Scahill
    Yale Child Study Center, Yale University, New Haven, CT 06520, USA
    J Am Acad Child Adolesc Psychiatry 45:1114-23. 2006
  9. ncbi request reprint Diagnosis and evaluation of pervasive developmental disorders
    Lawrence Scahill
    Yale University School of Medicine, New Haven, CT, USA
    J Clin Psychiatry 66:19-25. 2005
  10. ncbi request reprint A prospective open trial of guanfacine in children with pervasive developmental disorders
    Lawrence Scahill
    Yale Child Study Center, P O Box 207900, New Haven, CT 06520, USA
    J Child Adolesc Psychopharmacol 16:589-98. 2006

Research Grants

Detail Information

Publications60

  1. ncbi request reprint Methylphenidate: mechanism of action and clinical update
    Lawrence Scahill
    Yale University, New Haven, CT, USA
    J Child Adolesc Psychiatr Nurs 17:85-6. 2004
  2. ncbi request reprint Sudden death in a patient with Tourette syndrome during a clinical trial of ziprasidone
    Lawrence Scahill
    Child Study Center, School of Medicine and School of Nursing, Yale University, New Haven, CT 06520, USA
    J Psychopharmacol 19:205-6. 2005
  3. doi request reprint Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems
    Lawrence Scahill
    Child Study Center, New Haven, CT 06520, USA
    J Am Acad Child Adolesc Psychiatry 51:136-46. 2012
    ..Many children actually show a decline in adaptive skills compared with age mates over time...
  4. doi request reprint Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders
    Lawrence Scahill
    Yale University School of Nursing and Child Study Center, 230 S Frontage Rd, New Haven, CT, USA
    J Autism Dev Disord 42:432-40. 2012
    ..Study measures were similar to previous Research Units on Pediatric Psychopharmacology trials. Subjects in this trial were slightly older and more likely to have complaints of repetitive behavior than participants in RUPP trials...
  5. ncbi request reprint Psychosocial and clinical correlates of ADHD in a community sample of school-age children
    L Scahill
    Yale Child Study Center, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 38:976-84. 1999
    ..To identify the psychosocial and clinical correlates of attention-deficit hyperactivity disorder (ADHD) in a community sample of children and to examine the validity of a subclinical form of ADHD...
  6. ncbi request reprint Randomized trial of parent management training in children with tic disorders and disruptive behavior
    Lawrence Scahill
    Yale Child Study Center, New Haven, CT 06520 7900, USA
    J Child Neurol 21:650-6. 2006
    ..05). These results suggest that parent management training is helpful for short-term improvement in disruptive behavior problems in children with tic disorders. Larger randomized clinical trials are needed...
  7. ncbi request reprint Influence of age and tic disorders on obsessive-compulsive disorder in a pediatric sample
    Larry Scahill
    Yale Child Study Center, and Yale School of Nursing, New Haven, Connecticut 06520, USA
    J Child Adolesc Psychopharmacol 13:S7-17. 2003
    ..Obsessive-compulsive disorder (OCD) is a heterogeneous disorder with emerging data suggesting that age of onset and/or the presence of tics may define clinically important subgroups...
  8. ncbi request reprint Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders
    Lawrence Scahill
    Yale Child Study Center, Yale University, New Haven, CT 06520, USA
    J Am Acad Child Adolesc Psychiatry 45:1114-23. 2006
    ..To examine the psychometric properties of the Children's Yale-Brown Obsessive Compulsive Scales (CYBOCS) modified for pervasive developmental disorders (PDDs)...
  9. ncbi request reprint Diagnosis and evaluation of pervasive developmental disorders
    Lawrence Scahill
    Yale University School of Medicine, New Haven, CT, USA
    J Clin Psychiatry 66:19-25. 2005
    ..The elements of a contemporary diagnostic evaluation and behavioral assessment are presented. The application of discretionary evaluations for special situations are also introduced...
  10. ncbi request reprint A prospective open trial of guanfacine in children with pervasive developmental disorders
    Lawrence Scahill
    Yale Child Study Center, P O Box 207900, New Haven, CT 06520, USA
    J Child Adolesc Psychopharmacol 16:589-98. 2006
    ..A common complaint for children with pervasive developmental disorder (PDD) is hyperactivity. The purpose of this pilot study was to gather preliminary information on the efficacy of guanfacine in children with PDD and hyperactivity...
  11. ncbi request reprint A placebo-controlled trial of risperidone in Tourette syndrome
    L Scahill
    Child Study Center, School of Nursing, Yale University, New Haven, CT 06520, USA
    Neurology 60:1130-5. 2003
    ..To evaluate the efficacy and safety of risperidone in children and adults with Tourette syndrome...
  12. ncbi request reprint Treatment of hyperactivity in children with pervasive developmental disorders
    Lawrence Scahill
    Child Study Center, Yale University, New Haven, CT, USA
    J Child Adolesc Psychiatr Nurs 20:59-62. 2007
  13. ncbi request reprint Epidemiology of ADHD in school-age children
    L Scahill
    Yale University School of Nursing, New Haven, Connecticut, USA
    Child Adolesc Psychiatr Clin N Am 9:541-55, vii. 2000
    ..The review also examines age and gender effects on the frequency of ADHD. The article closes with a discussion of psychosocial correlates and patterns of comorbidity in ADHD...
  14. ncbi request reprint A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder
    L Scahill
    Yale Child Study Center, New Haven, CT 06520, USA
    Am J Psychiatry 158:1067-74. 2001
    ..This study evaluated the efficacy and safety of guanfacine in treating children with tic disorders and attention deficit hyperactivity disorder (ADHD)...
  15. ncbi request reprint Methodological issues in designing a multisite trial of risperidone in children and adolescents with autism
    L Scahill
    Research Unit on Pediatric Psychopharmacology Yale University, New Haven, Connecticut 06520, USA
    J Child Adolesc Psychopharmacol 11:377-88. 2001
    ..To describe the methodological challenges and decisions made in developing a multisite, controlled study of risperidone in children and adolescents with autism...
  16. doi request reprint Trial design challenges when combining medication and parent training in children with pervasive developmental disorders
    Lawrence Scahill
    Child Study Center, Yale University, New Haven, CT 06520, USA
    J Autism Dev Disord 39:720-9. 2009
    ..Thus, experimental evidence on the beneficial effects of combining pharmacotherapy and exportable behavioral interventions is needed to guide clinical practice...
  17. ncbi request reprint How do I decide whether or not to use medication for my child with autism? Should I try behavior therapy first?
    Lawrence Scahill
    Yale University, Child Study Center, 230 S Frontage Rd, PO Box 207900, New Haven, CT 06520, USA
    J Autism Dev Disord 38:1197-8. 2008
  18. ncbi request reprint Subject selection and characterization in clinical trials in children with autism
    Lawrence Scahill
    Department of Nursing, Child Study Center, Yale University at New Haven, CT 06520, USA
    CNS Spectr 9:22-32. 2004
    ....
  19. ncbi request reprint Risperidone approved for the treatment of serious behavioral problems in children with autism
    Lawrence Scahill
    Yale University
    J Child Adolesc Psychiatr Nurs 20:188-90. 2007
  20. ncbi request reprint The use of selective serotonin reuptake inhibitors in children and adolescents with major depression
    Lawrence Scahill
    Yale University School of Nursing and Child Study Center, USA
    J Child Adolesc Psychiatr Nurs 18:86-9. 2005
    ..Recent warnings about suicidal thoughts and self-injurious behavior in youth treated with selective serotonin reuptake inhibitors raise fundamental questions about the risk-benefit ratio of this class of medications...
  21. pmc Adulthood outcome of tic and obsessive-compulsive symptom severity in children with Tourette syndrome
    Michael H Bloch
    Yale Child Study Center, and General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    Arch Pediatr Adolesc Med 160:65-9. 2006
    ..One half to two thirds of children with TS experience a reduction or complete resolution of tic symptoms during adolescence. At least one third of adults with TS have comorbid obsessive-compulsive disorder (OCD)...
  22. ncbi request reprint Selective serotonin reuptake inhibitors for children and adolescents with major depression: current controversies and recommendations
    Vanya Hamrin
    Yale University School of Nursing and West Haven Mental Health Center, New Haven, CT 06536 0740, USA
    Issues Ment Health Nurs 26:433-50. 2005
    ..Appropriate use of the SSRIs in children and adolescents requires careful diagnostic assessment, evaluation of comorbidity, and close monitoring, especially early in treatment...
  23. ncbi request reprint Electrocardiographic changes in children and adolescents treated with ziprasidone: a prospective study
    Jennifer Blair
    Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 44:73-9. 2005
    ..To assess the electrocardiographic safety profile of low-dose ziprasidone (< or =40 mg/day) among pediatric outpatients treated for up to 6 months...
  24. ncbi request reprint Risperidone and adaptive behavior in children with autism
    Susan K Williams
    Yale University, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 45:431-9. 2006
    ..To evaluate the impact of risperidone on adaptive behavior in children with autistic disorder who have serious behavior problems and to examine different methods of scoring the Vineland Adaptive Behavior Scales to measure change...
  25. ncbi request reprint Drug and non-drug treatments of children with ADHD and tic disorders
    Yann Poncin
    Child Study Center, Yale University, P O Box 207900, New Haven, CT, 06520, USA
    Eur Child Adolesc Psychiatry 16:78-88. 2007
    ..To review the treatment of ADHD in children with chronic tic disorders...
  26. doi request reprint Promoting social skill development in children with pervasive developmental disorders: a feasibility and efficacy study
    Kathleen Koenig
    Yale Child Study Center, Yale School of Medicine, PO Box 207900, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 40:1209-18. 2010
    ..Parents reported a high level of satisfaction with the intervention. The study supports the feasibility of this intervention to families and highlights challenges for future research in social skills intervention...
  27. ncbi request reprint Tourette syndrome and tic disorders: a decade of progress
    James E Swain
    Child Study Center of Yale University, New Haven, CT, USA
    J Am Acad Child Adolesc Psychiatry 46:947-68. 2007
    ..This is a review of progress made in the understanding of Tourette syndrome (TS) during the past decade including models of pathogenesis, state-of-the-art assessment techniques, and treatment...
  28. ncbi request reprint Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning
    Denis G Sukhodolsky
    The Child Study Center, Yale University, 230 South Frontage Road, New Haven, CT 06520, USA
    J Abnorm Child Psychol 36:117-28. 2008
    ..Limited data are available on the prevalence of anxiety in these children. We examined frequency and correlates of parent-rated anxiety symptoms in a large sample of children with PDD...
  29. ncbi request reprint Multiple psychotropic pharmacotherapy among child and adolescent enrollees in Connecticut Medicaid managed care
    Andres Martin
    Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06520 7900, USA
    Psychiatr Serv 54:72-7. 2003
    ..The authors sought to determine the prevalence, patterns, and demographic correlates of multiple psychotropic pharmacotherapy in a statewide sample of low-income children and adolescents in community-based clinical care...
  30. ncbi request reprint Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment
    Denis G Sukhodolsky
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 42:98-105. 2003
    ..To examine the association of disruptive behavior with social, adaptive, and family functioning in Tourette's syndrome (TS) with and without comorbid attention-deficit/hyperactivity disorder (ADHD)...
  31. pmc Tourette syndrome and obsessive-compulsive disorder
    Paul J Lombroso
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, United States
    Brain Dev 30:231-7. 2008
    ..Recent advances in research models are also reviewed in an attempt to clarify some of the molecular etiologies that lead to these disorders...
  32. ncbi request reprint Assessment of symptom exacerbations in a longitudinal study of children with Tourette's syndrome or obsessive-compulsive disorder
    Haiqun Lin
    Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 41:1070-7. 2002
    ..A second major aim was to assess whether fluctuations in tic and OC symptom severity covaried with one another...
  33. doi request reprint Gastrointestinal symptoms in a sample of children with pervasive developmental disorders
    Roumen N Nikolov
    Yale Child Study Center, Yale University, P O Box 207900, New Haven, CT, USA
    J Autism Dev Disord 39:405-13. 2009
    ..Compared to children without GI problems, those with GI problems showed greater symptom severity on measures of irritability, anxiety, and social withdrawal. Those with GI problems were also less likely to respond to treatment...
  34. ncbi request reprint The challenge of providing continuity in the care of a disabled child: Smith-Lemli-Opitz syndrome
    Kathleen Koenig
    Yale Child Study Center, New Haven, Connecticut 06520, USA
    Issues Ment Health Nurs 23:641-8. 2002
    ..The role of nursing in facilitating collaboration among families, members of the health care team, and advocacy agencies, particularly in children with complex medical and psychiatric difficulties, is highlighted...
  35. pmc Neuropsychological functioning in children with Tourette syndrome with and without attention-deficit/hyperactivity disorder
    Denis G Sukhodolsky
    Yale Child Study Center, 230 South Frontage Road, PO Box 207900, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 49:1155-64. 2010
    ..We examined neuropsychological functioning in relatively large and well-characterized samples of children categorized as TS, TS-plus-ADHD, ADHD, and unaffected controls...
  36. doi request reprint Selecting measures for use in child mental health services: a scorecard approach
    Erin M Warnick
    Yale University Child Study Center, New Haven, CT 06510, USA
    Adm Policy Ment Health 36:112-22. 2009
    ..Results may improve clinical practice by providing an empirical approach to the selection of assessment tools...
  37. doi request reprint Randomized trial of anger control training for adolescents with Tourette's syndrome and disruptive behavior
    Denis G Sukhodolsky
    Yale Child Study Center, New Haven, CT 06520 7900, USA
    J Am Acad Child Adolesc Psychiatry 48:413-21. 2009
    ..To evaluate the efficacy of a 10-session individually administered anger control training (ACT) for adolescents with Tourette's syndrome (TS) and disruptive behavior...
  38. doi request reprint Group intervention to promote social skills in school-age children with pervasive developmental disorders: reconsidering efficacy
    Kathleen Koenig
    Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, PO Box 207900, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 39:1163-72. 2009
    ..The existing paradigm for evaluating the evidence base of intervention may need modification to permit a more intricate analysis of the extant research, and increase the sophistication of future research...
  39. doi request reprint Alpha-2 adrenergic agonists in children with inattention, hyperactivity and impulsiveness
    Lawrence Scahill
    Child Study Center, Yale University School of Medicine and Yale School of Nursing, New Haven, Connecticut 06520, USA
    CNS Drugs 23:43-9. 2009
    ..Both clonidine and guanfacine are associated with sedation, fatigue and somnolence. Reductions in heart rate and blood pressure are modest and rarely lead to discontinuation of treatment across these trials...
  40. doi request reprint Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndrome
    Maria G Motlagh
    Child Study Center, Yale University School of Medicine, I 383 SHM, 230 South Frontage Road, New Haven, CT 06520 7920, USA
    Eur Child Adolesc Psychiatry 19:755-64. 2010
    ..Efforts are needed to reduce the frequency of these risk factors in high-risk populations. Future studies, using genetically sensitive designs, are also needed to sort out the causal pathways...
  41. pmc Adaptive, emotional, and family functioning of children with obsessive-compulsive disorder and comorbid attention deficit hyperactivity disorder
    Denis G Sukhodolsky
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    Am J Psychiatry 162:1125-32. 2005
    ....
  42. doi request reprint The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder
    Denis G Sukhodolsky
    Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT, 06520, USA
    Eur Child Adolesc Psychiatry 16:51-9. 2007
    ..To examine the role of aberrant neural oscillatory activity in the pathophysiology of co-occurring Tourette Syndrome (TS) and Attention-Deficit/Hyperactivity Disorder (ADHD)...
  43. ncbi request reprint Acute stress disorder symptoms in gunshot-injured youth
    Vanya Hamrin
    Yale University, School of Nursing, New Haven, CT, USA
    J Child Adolesc Psychiatr Nurs 17:161-72. 2004
    ..The prevalence of acute stress disorder symptoms (ASDS) and other psychiatric comorbidities in youth with recent gunshot injuries...
  44. ncbi request reprint Weight and leptin changes among risperidone-treated youths with autism: 6-month prospective data
    Andres Martin
    Yale Child Study Center, Yale University, New Haven, CT 06520, USA
    Am J Psychiatry 161:1125-7. 2004
    ..The authors examined the developmental impact and temporal characteristics of risperidone-associated weight change...
  45. ncbi request reprint Effects of short- and long-term risperidone treatment on prolactin levels in children with autism
    George M Anderson
    Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 61:545-50. 2007
    ..The effects of short- and long-term risperidone treatment on serum prolactin were assessed in children and adolescents with autism...
  46. ncbi request reprint Datapoints: use of multiple psychotropic drugs by Medicaid-insured and privately insured children
    Andres Martin
    Yale University School of Medicine, 230 South Frontage Road, PO Box 207900, New Haven, CT 06520 7900, USA
    Psychiatr Serv 53:1508. 2002
  47. ncbi request reprint Tourette syndrome: the self under siege
    James F Leckman
    Yale Child Study Center, New Haven, CT 06510, USA
    J Child Neurol 21:642-9. 2006
    ....
  48. ncbi request reprint alpha2-Adrenergic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: emerging concepts from new data
    AMY F ARNSTEN
    Director of Graduate Studies, Deparment of Neurobiology, Yale Medical School, New Haven, Connecticut 06520 8001, USA
    J Child Adolesc Psychopharmacol 17:393-406. 2007
    ..Knowledge of these basic mechanisms may inform our medication choices and facilitate treatment of ADHD and related disorders...
  49. ncbi request reprint Low-dose fluvoxamine treatment of children and adolescents with pervasive developmental disorders: a prospective, open-label study
    Andres Martin
    Child Study Center, Yale University, New Haven, Connecticut 06520 7900, USA
    J Autism Dev Disord 33:77-85. 2003
    ..Fluvoxamine can be beneficial in the treatment of select children and adolescents with PDDs. Gender differences in selective serotonin reuptake inhibitor (SSRI) response warrant further investigation...
  50. pmc Contemporary assessment and pharmacotherapy of Tourette syndrome
    Lawrence Scahill
    Yale Child Study Center, 230 South Frontage Road, P O Box 207900, New Haven, CT 06520, USA
    NeuroRx 3:192-206. 2006
    ..The evidence supporting efficacy and safety for medications used in patients with TS varies. But this evidence offers the best guide to clinical practice...
  51. ncbi request reprint Cardiac conduction and antipsychotic medication: a primer on electrocardiograms
    Deirdre H Carroll
    Yale Child Study Center, Yale University School of Nursing, New Haven, CT, USA
    J Child Adolesc Psychiatr Nurs 15:170-7. 2002
  52. ncbi request reprint Nonstimulant medications for the treatment of ADHD
    Adrienne Rains
    Yale University, USA
    J Child Adolesc Psychiatr Nurs 19:44-7. 2006
  53. ncbi request reprint Disruptive behavior problems in a community sample of children with tic disorders
    Lawrence Scahill
    Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Adv Neurol 99:184-90. 2006
  54. ncbi request reprint [Autistic disorder: current psychopharmacological treatments and areas of interest for future developments]
    Roumen Nikolov
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Rev Bras Psiquiatr 28:S39-46. 2006
    ..The aim of this review is to highlight the available current pharmacotherapies and those emerging treatments with potential to enhance the treatment options of patients with pervasive developmental disorders...
  55. ncbi request reprint New long-acting stimulants in children with ADHD
    Adrienne Rains
    Yale Child Study Center, New Haven, CT, USA
    J Child Adolesc Psychiatr Nurs 17:177-9. 2004
  56. ncbi request reprint Public health significance of tic disorders in children and adolescents
    Lawrence Scahill
    Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Adv Neurol 96:240-8. 2005
    ..Community samples and recent investigations in clinical samples confirm that the presence of ADHD predicts greater disability than that associated with tic disorders alone...
  57. ncbi request reprint An animal model of Tourette's syndrome
    Jane R Taylor
    Child Study Center, Children s Clinical Research Center, School of Nursing, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Psychiatry 159:657-60. 2002
    ..An animal model was used to investigate an autoimmune etiology for some cases of Tourette's syndrome...
  58. ncbi request reprint Phenomenology of tics and natural history of tic disorders
    James F Leckman
    Child Study Center, Sterling Hall of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Adv Neurol 99:1-16. 2006
  59. ncbi request reprint Deep brain stimulation in Tourette's syndrome
    Rizma Jalees Bajwa
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Mov Disord 22:1346-50. 2007
    ..DBS resulted in a substantial reduction of tics. These data show that bilateral DBS of the thalamus can have a good effect on severe tics in adult patients suffering from intractable TS...
  60. ncbi request reprint Psychopharmacological treatment for very young children: contexts and guidelines
    Mary Margaret Gleason
    Bradley Hasbro Research Center, Providence, RI 02903, USA
    J Am Acad Child Adolesc Psychiatry 46:1532-72. 2007
    ..The purpose of this effort is to promote responsible treatment of young children, recognizing that this will sometimes involve the use of medications...

Research Grants10

  1. 4/4-RUPP Autism Network: Guanfacine for the Treatment of Hyperactivity in PDD
    LAWRENCE D SCAHILL; Fiscal Year: 2010
    ..The role of gene variants and urinary adrenergic/noradrenergic measures as biomarkers in moderating response to guanfacine on primary efficacy measures and adverse effects will be explored. ..
  2. Behavior Therapy for Adults with Tourette Syndrome
    Lawrence Scahill; Fiscal Year: 2009
    ..The Informatics group at Yale University will provide data management services. ..
  3. 1/5-Randomized Trial of Parent Training for Young Children with Autism
    LAWRENCE D SCAHILL; Fiscal Year: 2010
    ..This trial is designed to address this need by providing information on optimal practices for educating parents to be effective teachers and advocates for their young children. ..
  4. RUPP-PI Program at Yale University
    Lawrence Scahill; Fiscal Year: 2006
    ..Furthermore, this five-site network has established reliability on several measures that are relevant to the conduct of clinical trials in children with PDD. ..
  5. Anger Control Training for Youth with Tourette Syndrome
    Larry Scahill; Fiscal Year: 2005
    ..This design will permit demonstration of a clinically relevant effect size for anger control training in adolescents with TS. ..