Mary Savoye

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi request reprint Reversal of early abnormalities in glucose metabolism in obese youth: results of an intensive lifestyle randomized controlled trial
    Mary Savoye
    Corresponding author Mary Savoye
    Diabetes Care 37:317-24. 2014
  2. ncbi request reprint Effects of a weight management program on body composition and metabolic parameters in overweight children: a randomized controlled trial
    Mary Savoye
    Yale Center for Clinical Investigation, Yale University School of Medicine, New Haven, CT 06520, USA
    JAMA 297:2697-704. 2007
  3. pmc Long-term results of an obesity program in an ethnically diverse pediatric population
    Mary Savoye
    Yale University School of Medicine, Pediatric Endocrinology, PO Box 208064, New Haven, CT 06520 8064, USA
    Pediatrics 127:402-10. 2011
  4. ncbi request reprint Anthropometric and psychosocial changes in obese adolescents enrolled in a Weight Management Program
    Mary Savoye
    Department of Pediatric Endocrinology and General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    J Am Diet Assoc 105:364-70. 2005
  5. ncbi request reprint High visceral and low abdominal subcutaneous fat stores in the obese adolescent: a determinant of an adverse metabolic phenotype
    Sara E Taksali
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520, USA
    Diabetes 57:367-71. 2008
  6. ncbi request reprint Predictors of changes in glucose tolerance status in obese youth
    Ram Weiss
    Yale University School of Medicine, Department of Pediatrics, P O Box 802064, New Haven, CT 06520, USA
    Diabetes Care 28:902-9. 2005
  7. pmc Hepatic fat accumulation is modulated by the interaction between the rs738409 variant in the PNPLA3 gene and the dietary omega6/omega3 PUFA intake
    Nicola Santoro
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 7:e37827. 2012
  8. ncbi request reprint Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat
    Tania S Burgert
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 91:4287-94. 2006
  9. ncbi request reprint Obesity and the metabolic syndrome in children and adolescents
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    N Engl J Med 350:2362-74. 2004
  10. pmc Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Lancet 362:951-7. 2003

Collaborators

Detail Information

Publications21

  1. doi request reprint Reversal of early abnormalities in glucose metabolism in obese youth: results of an intensive lifestyle randomized controlled trial
    Mary Savoye
    Corresponding author Mary Savoye
    Diabetes Care 37:317-24. 2014
    ..CONCLUSIONS Compared with standard of care, the Yale BB Program is a more effective means of reducing the risk of T2D in obese adolescents with elevated 2-h glucose levels. ..
  2. ncbi request reprint Effects of a weight management program on body composition and metabolic parameters in overweight children: a randomized controlled trial
    Mary Savoye
    Yale Center for Clinical Investigation, Yale University School of Medicine, New Haven, CT 06520, USA
    JAMA 297:2697-704. 2007
    ..Since most overweight children become overweight adults, this chronic condition results in serious metabolic complications by early adulthood. To curtail this major health issue, effective pediatric interventions are essential...
  3. pmc Long-term results of an obesity program in an ethnically diverse pediatric population
    Mary Savoye
    Yale University School of Medicine, Pediatric Endocrinology, PO Box 208064, New Haven, CT 06520 8064, USA
    Pediatrics 127:402-10. 2011
    ..To determine if beneficial effects of a weight-management program could be sustained for up to 24 months in a randomized trial in an ethnically diverse obese population...
  4. ncbi request reprint Anthropometric and psychosocial changes in obese adolescents enrolled in a Weight Management Program
    Mary Savoye
    Department of Pediatric Endocrinology and General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    J Am Diet Assoc 105:364-70. 2005
    ..To determine short- and long-term effects of the Bright Bodies Weight Management Program on obese adolescents and to further observe if a diet or nondiet approach is more successful...
  5. ncbi request reprint High visceral and low abdominal subcutaneous fat stores in the obese adolescent: a determinant of an adverse metabolic phenotype
    Sara E Taksali
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520, USA
    Diabetes 57:367-71. 2008
    ....
  6. ncbi request reprint Predictors of changes in glucose tolerance status in obese youth
    Ram Weiss
    Yale University School of Medicine, Department of Pediatrics, P O Box 802064, New Haven, CT 06520, USA
    Diabetes Care 28:902-9. 2005
    ..Type 2 diabetes in obese youth is an emerging problem. The metabolic and anthropometric predictors of change in glucose tolerance status in obese youth are unknown...
  7. pmc Hepatic fat accumulation is modulated by the interaction between the rs738409 variant in the PNPLA3 gene and the dietary omega6/omega3 PUFA intake
    Nicola Santoro
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 7:e37827. 2012
    ....
  8. ncbi request reprint Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat
    Tania S Burgert
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 91:4287-94. 2006
    ..Nevertheless, the complete metabolic phenotype associated with abnormalities in biomarkers of liver injury and intrahepatic fat accumulation remains to be established...
  9. ncbi request reprint Obesity and the metabolic syndrome in children and adolescents
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    N Engl J Med 350:2362-74. 2004
    ....
  10. pmc Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Lancet 362:951-7. 2003
    ..We investigated whether altered partitioning of myocellular and abdominal fat relates to abnormalities in glucose homoeostasis in obese adolescents with prediabetes...
  11. pmc Effect of a successful intensive lifestyle program on insulin sensitivity and glucose tolerance in obese youth
    Melissa Shaw
    Department of Pediatrics, Yale University, New Haven, Connecticut, USA
    Diabetes Care 32:45-7. 2009
    ..To evaluate the impact on glucose metabolism of a lifestyle program (the Yale Bright Bodies Program) for obese children...
  12. pmc Utility of hemoglobin A(1c) for diagnosing prediabetes and diabetes in obese children and adolescents
    Paulina Nowicka
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 34:1306-11. 2011
    ..This recommendation is based on data in adults showing the relationship between A1C with future development of diabetes and microvascular complications. However, studies in the pediatric population are lacking...
  13. doi request reprint Rosiglitazone improves glucose metabolism in obese adolescents with impaired glucose tolerance: a pilot study
    Anna M G Cali
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Obesity (Silver Spring) 19:94-9. 2011
    ..The short-term use of ROSI appears to be safe in obese adolescents with IGT. ROSI restores NGT by increasing peripheral insulin sensitivity and β-cell function, two principal pathophysiological abnormalities of IGT...
  14. pmc Ethnic differences in lipoprotein subclasses in obese adolescents: importance of liver and intraabdominal fat accretion
    Ebe D'Adamo
    Department of Pediatrics, Yale University, New Haven, CT, USA
    Am J Clin Nutr 92:500-8. 2010
    ..Recently, the deleterious metabolic effects of visceral fat [visceral adipose tissue (VAT)] deposition were challenged, and liver fat emerged as having a key independent role in the modulation of cardiometabolic risk factors...
  15. pmc A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents
    Nicola Santoro
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Hepatology 52:1281-90. 2010
    ..03) and sirtuin 1 (SIRT1) expression (P = 0.04)...
  16. pmc Glucose dysregulation and hepatic steatosis in obese adolescents: is there a link?
    Anna M G Cali
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Hepatology 49:1896-903. 2009
    ..7% of the subjects in the high HFF had the metabolic syndrome compared to 19.5% and 30.6%, respectively, in the low and moderate categories. Both total and HMW-adiponectin decreased, and IL-6 increased with increasing hepatic steatosis...
  17. ncbi request reprint Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity
    Ranjana Sinha
    Department of Pediatrics, The Children s General Clinical Research Center at Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Diabetes 51:1022-7. 2002
    ..The striking relationships between both IMCL and EMCL with insulin sensitivity in childhood suggest that these findings are not a consequence of aging but occur early in the natural course of obesity...
  18. doi request reprint Preventing diabetes among Fair Haven families: a community-based approach to quality improvement
    Rosette J Chakkalakal
    Robert Wood Johnson Foundation Clinical Scholars Program, Yale University School of Medicine, 333 Cedar Street, SHM IE 61, New Haven, CT 06520 8088, USA
    J Health Care Poor Underserved 23:247-54. 2012
    ....
  19. ncbi request reprint Prevalence of impaired glucose tolerance among children and adolescents with marked obesity
    Ranjana Sinha
    Department of Pediatrics, Yale University School of Medicine, New Haven, Conn 06520, USA
    N Engl J Med 346:802-10. 2002
    ..We determined the prevalence of impaired glucose tolerance in a multiethnic cohort of 167 obese children and adolescents...
  20. pmc Demographic, dietary, and biochemical determinants of vitamin D status in inner-city children
    Thomas O Carpenter
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Am J Clin Nutr 95:137-46. 2012
    ..Reports of clinical rickets are particularly evident in minority infants and children, but only limited analyses of vitamin D are available in this demographic group...
  21. pmc An intervention for multiethnic obese parents and overweight children
    Diane Berry
    University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7460, USA
    Appl Nurs Res 20:63-71. 2007
    ..Children in the experimental group demonstrated trends toward decreased BMI and BFP and increased pedometer steps...