Affiliation: Yale University
- A simplified method for combined immunohistochemistry and in-situ hybridization in fresh-frozen, cryocut mouse brain sectionsSathyanesan Samuel Newton
Division of Molecular Psychiatry, Department of Psychiatry, Yale School of Medicine, S 304, CMHC, 34 Park Street, New Haven, CT 06508, USA
Brain Res Brain Res Protoc 9:214-9. 2002....
- Vascular growth factors in neuropsychiatrySamuel S Newton
Departments of Psychiatry and Neurobiology, Laboratory of Molecular Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT, 06508, USA
Cell Mol Life Sci 70:1739-52. 2013..Obtaining insight into the behavioral, cellular and molecular actions of multi-functional trophic factors has the potential to open new and transformative therapeutic approaches...
- Customizing microarrays for neuroscience drug discoveryMatthew J Girgenti
Yale University School of Medicine, Division of Molecular Psychiatry, Departments of Psychiatry and Pharmacology, 34 Park Street, New Haven, CT, 06508, USA 1 203 974 7733 1 203 974 7897
Expert Opin Drug Discov 2:1139-49. 2007..The notion that a hypothesis-driven approach can be integrated into drug development programs is highlighted...
- Production of custom microarrays for neuroscience researchSamuel S Newton
Division of Molecular Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA
Methods 37:238-46. 2005..The custom microarray approach is presented with procedural details for design and production in the context of neurobiological investigations...
- Electroconvulsive seizure increases adult hippocampal angiogenesis in ratsSamuel S Newton
Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, CT, USA
Eur J Neurosci 24:819-28. 2006..Increases in the vascular density of the SLM could be in response to enhanced metabolic activity in this region. This is supported by the induction of glutamine synthetase and the glutamate transporter GLT1...
- Characterization of electroconvulsive seizure-induced TIMP-1 and MMP-9 in hippocampal vasculatureMatthew J Girgenti
Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, CT 06508, USA
Int J Neuropsychopharmacol 14:535-44. 2011..These studies suggest that ECS-induced remodelling occurs at the vascular basement membrane and facilitates neovascularization...
- Erythropoietin induction by electroconvulsive seizure, gene regulation, and antidepressant-like behavioral effectsMatthew J Girgenti
Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut, USA
Biol Psychiatry 66:267-74. 2009..It is believed that the behavioral effects are mediated by EPO's trophic effect on neuronal systems. We therefore tested whether EPO is able to alter behavior and brain gene expression in rats...
- GENE-EXPRESSION CHANGE IN HUMAN BLOOD SAMPLES AND ANTI-DEPRESSANT RESPONSESAMUEL SATHYANESAN; Fiscal Year: 2004..Briefly, further studies would involve examening differences among different types of depressive disorders and the correlation between gene-expression changes and treatment-response. ..
- Choroid plexus & antidepressants: genomics & proteomicsSAMUEL SATHYANESAN; Fiscal Year: 2007....