B J Rounsaville

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Experience with ICD-10/DSM-IV substance use disorders
    Bruce J Rounsaville
    Yale University School of Medicine, VA CT Healthcare Systems, West Haven, CT 06516, USA
    Psychopathology 35:82-8. 2002
  2. ncbi request reprint Treatment of cocaine dependence and depression
    Bruce J Rounsaville
    Department of Psychiatry, Yale University School of Medicine, New Haven, and Veterans Affairs Connecticut Healthcare, West Haven, Connecticut 06516, USA
    Biol Psychiatry 56:803-9. 2004
  3. ncbi request reprint Options for managing psychotropic medications in drug-abusing patients participating in behavioral therapies clinical trials
    B J Rounsaville
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn 06519, USA
    Am J Addict 8:178-89. 1999
  4. pmc Single versus multiple drug focus in substance abuse clinical trials research
    Bruce J Rounsaville
    Department of Psychiatry, Division of Substance Abuse, Yale University, West Haven, CT 06516, USA
    Drug Alcohol Depend 70:117-25. 2003
  5. ncbi request reprint Primary care-based ambulatory opioid detoxification: the results of a clinical trial
    M E Waugh
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8025, USA
    J Gen Intern Med 10:255-60. 1995
  6. ncbi request reprint When is less treatment better? The role of social anxiety in matching methadone patients to psychosocial treatments
    S K Avants
    Substance Abuse Center, Yale University School of Medicine, New Haven, Connecticut 06529, USA
    J Consult Clin Psychol 66:924-31. 1998
  7. ncbi request reprint A general system for evaluating therapist adherence and competence in psychotherapy research in the addictions
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Drug Alcohol Depend 57:225-38. 2000
  8. ncbi request reprint Illegal behaviors in problem gambling: analysis of data from a gambling helpline
    M N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    J Am Acad Psychiatry Law 28:389-403. 2000
  9. ncbi request reprint Internal validity of Project MATCH treatments: discriminability and integrity
    K M Carroll
    Yale University School of Medicine, New Haven, Connecticut, USA
    J Consult Clin Psychol 66:290-303. 1998
  10. ncbi request reprint Day treatment versus enhanced standard methadone services for opioid-dependent patients: a comparison of clinical efficacy and cost
    S K Avants
    Yale University School of Medicine, Conn, USA
    Am J Psychiatry 156:27-33. 1999

Research Grants

  1. Diagnosis & Treatment of Substance Use Disorder
    Bruce Rounsaville; Fiscal Year: 2007
  2. Clinician Scientist Training in Substance Abuse Research
    Bruce Rounsaville; Fiscal Year: 2007

Detail Information

Publications88

  1. ncbi request reprint Experience with ICD-10/DSM-IV substance use disorders
    Bruce J Rounsaville
    Yale University School of Medicine, VA CT Healthcare Systems, West Haven, CT 06516, USA
    Psychopathology 35:82-8. 2002
    ..Nevertheless, more research is needed particularly to examine the comparative reliability and validity of abuse and harmful use diagnoses...
  2. ncbi request reprint Treatment of cocaine dependence and depression
    Bruce J Rounsaville
    Department of Psychiatry, Yale University School of Medicine, New Haven, and Veterans Affairs Connecticut Healthcare, West Haven, Connecticut 06516, USA
    Biol Psychiatry 56:803-9. 2004
    ....
  3. ncbi request reprint Options for managing psychotropic medications in drug-abusing patients participating in behavioral therapies clinical trials
    B J Rounsaville
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn 06519, USA
    Am J Addict 8:178-89. 1999
    ..However, experimental rigor can be maintained while allowing subjects to use ancillary medications if steps are taken to monitor and minimize the variability in treatment delivery...
  4. pmc Single versus multiple drug focus in substance abuse clinical trials research
    Bruce J Rounsaville
    Department of Psychiatry, Division of Substance Abuse, Yale University, West Haven, CT 06516, USA
    Drug Alcohol Depend 70:117-25. 2003
    ..Although many treatment efficacy questions can best be answered by single focus studies, we recommend that such designs be adopted only after less restrictive designs are first considered...
  5. ncbi request reprint Primary care-based ambulatory opioid detoxification: the results of a clinical trial
    M E Waugh
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8025, USA
    J Gen Intern Med 10:255-60. 1995
    ..Ambulatory opioid detoxification can give internists a larger role in initiating drug treatment for IDUs who are addicted to opioids...
  6. ncbi request reprint When is less treatment better? The role of social anxiety in matching methadone patients to psychosocial treatments
    S K Avants
    Substance Abuse Center, Yale University School of Medicine, New Haven, Connecticut 06529, USA
    J Consult Clin Psychol 66:924-31. 1998
    ....
  7. ncbi request reprint A general system for evaluating therapist adherence and competence in psychotherapy research in the addictions
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Drug Alcohol Depend 57:225-38. 2000
    ..Strategies for using the YACS in both psychotherapy and pharmacotherapy research in the addictions are described...
  8. ncbi request reprint Illegal behaviors in problem gambling: analysis of data from a gambling helpline
    M N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    J Am Acad Psychiatry Law 28:389-403. 2000
    ..The results of the present study highlight the importance of the identification and treatment of individuals with gambling problems with respect to legal issues...
  9. ncbi request reprint Internal validity of Project MATCH treatments: discriminability and integrity
    K M Carroll
    Yale University School of Medicine, New Haven, Connecticut, USA
    J Consult Clin Psychol 66:290-303. 1998
    ..Nonspecific aspects of treatment such as therapist skillfulness and level of the therapeutic alliance were comparable across treatment conditions...
  10. ncbi request reprint Day treatment versus enhanced standard methadone services for opioid-dependent patients: a comparison of clinical efficacy and cost
    S K Avants
    Yale University School of Medicine, Conn, USA
    Am J Psychiatry 156:27-33. 1999
    ....
  11. ncbi request reprint One-year follow-up of disulfiram and psychotherapy for cocaine-alcohol users: sustained effects of treatment
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, USA
    Addiction 95:1335-49. 2000
    ..To evaluate outcomes 1 year after cessation of treatment for cocaine- and alcohol-dependent individuals...
  12. pmc Combining cognitive behavioral therapy with contingency management for smoking cessation in adolescent smokers: a preliminary comparison of two different CBT formats
    Dana A Cavallo
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Am J Addict 16:468-74. 2007
    ..In addition, significantly more participants in the CBT group completed treatment. These preliminary results suggest that when combined with CM, the standard weekly format of CBT is more acceptable to adolescent smokers...
  13. ncbi request reprint Personality disorder and dimension differences between type A and type B substance abusers
    S A Ball
    Yale University School of Medicine, Department of Psychiatry, New Haven, Connecticut, USA
    J Pers Disord 12:1-12. 1998
    ..These subtype differences remained after controlling for the effects of antisocial personality and psychiatric symptoms...
  14. ncbi request reprint Gender-related differences in the characteristics of problem gamblers using a gambling helpline
    M N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven 06519, USA
    Am J Psychiatry 158:1500-5. 2001
    ..The characteristics of male and female gamblers utilizing a gambling helpline were examined to identify gender-related differences...
  15. ncbi request reprint Disulfiram treatment for cocaine dependence in methadone-maintained opioid addicts
    I L Petrakis
    Department of Psychiatry, Yale University, New Haven, Connecticut, USA
    Addiction 95:219-28. 2000
    ..We evaluated the efficacy of disulfiram for cocaine dependence, both with and without co-morbid alcohol abuse, in a group of methadone-maintained opioid addicts...
  16. ncbi request reprint Reliability of personality disorder symptoms and personality traits in substance-dependent inpatients
    S A Ball
    Department of Psychiatry, Yale University School of Medicine, USA
    J Abnorm Psychol 110:341-52. 2001
    ..The authors did not find that the five factors were more reliable than the Axis II symptoms. Issues related to the reliability of personality assessment in multiply diagnosed patients are discussed...
  17. ncbi request reprint Opioid-, cannabis- and alcohol-dependent women show more rapid progression to substance abuse treatment
    Carlos A Hernandez-Avila
    Department of Psychiatry, Alcohol Research Center, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
    Drug Alcohol Depend 74:265-72. 2004
    ..e., "telescoping") of alcohol-related complications. This phenomenon also appears to be evident in drug-dependent women, though the data available to support telescoping in drug dependence is less abundant...
  18. ncbi request reprint Ambulatory opiate detoxification and primary care: a role for the primary care physician
    M E Waugh
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510
    J Gen Intern Med 7:532-4. 1992
    ..0001). Of 45 patients who ultimately completed AOD, 78% (35/45) remained in treatment for at least one month...
  19. pmc Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: efficacy of contingency management and significant other involvement
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, VA CT Healthcare System, 950 Campbell Ave 151D, West Haven, CT 06516, USA
    Arch Gen Psychiatry 58:755-61. 2001
    ..Contingency management (CM) and significant other involvement (SO) were evaluated as strategies to enhance treatment retention, medication compliance, and outcome for naltrexone treatment of opioid dependence...
  20. ncbi request reprint Multidimensional subtypes and treatment outcome in first-time DWI offenders
    S A Ball
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Addict Behav 25:167-81. 2000
    ..Although Type A/B may be an important theoretical model for guiding alcoholism research, it usefulness and efficiency for treatment matching, planning, or placement purposes is questioned...
  21. ncbi request reprint Naltrexone and cognitive behavioral coping skills therapy for the treatment of alcohol drinking and eating disorder features in alcohol-dependent women: a randomized controlled trial
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 31:625-34. 2007
    ..This study investigated the safety and efficacy of naltrexone in combination with Cognitive Behavioral Coping Skills Therapy (CBCST) in a sample of alcohol-dependent women, some with comorbid eating pathology...
  22. pmc Measuring money mismanagement among dually diagnosed clients
    Ryan A Black
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    J Nerv Ment Dis 196:576-9. 2008
    ..Results suggest that the interview is sensitive in detecting money mismanagement and raises questions concerning the validity of clinicians' judgments...
  23. pmc Computer-assisted delivery of cognitive-behavioral therapy for addiction: a randomized trial of CBT4CBT
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Ave, 151D, West Haven, CT 06516, USA
    Am J Psychiatry 165:881-8. 2008
    ..This study evaluated the efficacy of a computer-based version of cognitive-behavioral therapy (CBT) for substance dependence...
  24. doi request reprint Drug abuse and responsible fathering: a comparative study of men enrolled in methadone maintenance treatment
    Thomas J McMahon
    Yale University School of Medicine, West Haven Mental Health Clinic, West Haven, CT 06516, USA
    Addiction 103:269-83. 2008
    ..Because very little is known about the parenting of drug-abusing men, this study was designed to document ways that drug abuse contributes to compromise of responsible fathering...
  25. pmc The use of contingency management and motivational/skills-building therapy to treat young adults with marijuana dependence
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    J Consult Clin Psychol 74:955-66. 2006
    ..Participants assigned to MET/CBT continued to reduce the frequency of their marijuana use through a 6-month follow-up...
  26. pmc Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men
    Scott M Hyman
    Yale Research Program on Stress, Addiction, and Psychopathology, Department of Psychiatry, Yale University School of Medicine, 34 Park Street, Room S110, New Haven, CT 06511, USA
    Drug Alcohol Depend 92:208-16. 2008
    ..Comprehensive assessments of childhood trauma and specialized treatments that address trauma-related pathophysiology could be of benefit in improving cocaine treatment outcomes in women...
  27. pmc A perfect platform: combining contingency management with medications for drug abuse
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Am J Drug Alcohol Abuse 33:343-65. 2007
    ....
  28. pmc DSM-V research agenda: substance abuse/psychosis comorbidity
    Bruce J Rounsaville
    VA CT Healthcare System, 950 Campbell Avenue 151D, West Haven, CT 06516, USA
    Schizophr Bull 33:947-52. 2007
    ..Given the strong association between SUDs and psychotic disorders, research on the neurobiology of psychotic disorders could fruitfully include subjects with comorbid SUDs to shed light on shared etiology and pathophysiology...
  29. pmc A vision of the next generation of behavioral therapies research in the addictions
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 102:850-62; discussion 863-9. 2007
    ....
  30. ncbi request reprint Differences in treatment outcome between male alcohol dependent offenders of domestic violence with and without positive drug screens
    Caroline J Easton
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine SATU, Box 18, 1 Long Wharf, New Haven, CT 06511, USA
    Addict Behav 32:2151-63. 2007
    ..The findings suggest that alcohol dependent men who continue to use illicit drugs may require additional interventions to effectively control their drug use and, their anger management styles...
  31. pmc Drug-abusing fathers: patterns of pair bonding, reproduction, and paternal involvement
    Thomas J McMahon
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    J Subst Abuse Treat 33:295-302. 2007
    ....
  32. ncbi request reprint Concurrent and predictive validity of drug use and psychiatric diagnosis among first-time DWI offenders
    Rebekka S Palmer
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Alcohol Clin Exp Res 31:619-24. 2007
    ..Previous studies have found that driving while intoxicated (DWI) offenders report high rates of substance dependence and other psychiatric disorders...
  33. pmc Pretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients
    Judson A Brewer
    Yale University School of Medicine, Department of Psychiatry, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Biol Psychiatry 64:998-1004. 2008
    ..No prior studies have systematically examined the neural correlates of cognitive control as related to treatment outcomes for cocaine dependence...
  34. pmc Enduring effects of a computer-assisted training program for cognitive behavioral therapy: a 6-month follow-up of CBT4CBT
    Kathleen M Carroll
    Yale University School of Medicine, Division of Substance Abuse, 950 Campbell Avenue, 151D West Haven, CT 06516, USA
    Drug Alcohol Depend 100:178-81. 2009
    ..To evaluate the durability of effects of a computer-assisted version of cognitive behavioral therapy (CBT) as treatment for substance dependence through a 6-month follow-up...
  35. pmc Teaching community program clinicians motivational interviewing using expert and train-the-trainer strategies
    Steve Martino
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Addiction 106:428-41. 2011
    ..The effectiveness of expert-led (EX) and train-the-trainer (TT) strategies was compared to a self-study approach (SS) for teaching clinicians motivational interviewing (MI)...
  36. pmc Screening for prenatal substance use: development of the Substance Use Risk Profile-Pregnancy scale
    Kimberly A Yonkers
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Obstet Gynecol 116:827-33. 2010
    ..To report on the development of a questionnaire to screen for hazardous substance use in pregnant women and to compare the performance of the questionnaire with other drug and alcohol measures...
  37. pmc Computer-assisted therapy in psychiatry: be brave-it's a new world
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Curr Psychiatry Rep 12:426-32. 2010
    ....
  38. pmc Conventional and unconventional treatments for stress among methadone-maintained patients: treatment willingness and perceived efficacy
    Declan T Barry
    Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Addict 20:137-42. 2011
    ..These findings are likely to have implications for resource and program planning in MMT programs. ..
  39. pmc Biological markers of the effects of intravenous methylphenidate on improving inhibitory control in cocaine-dependent patients
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA
    Proc Natl Acad Sci U S A 107:14455-9. 2010
    ..Altered ventromedial prefrontal activation and increased blood pressure may represent useful CNS and peripheral biomarkers in individualized treatment with methylphenidate for patients with cocaine dependence...
  40. pmc Advisor-Teller Money Manager (ATM) therapy for substance use disorders
    Marc I Rosen
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Psychiatr Serv 61:707-13. 2010
    ..This randomized clinical trial was conducted to determine the effect of a money management-based therapy, advisor-teller money manager (ATM), on substance abuse or dependence...
  41. pmc Increased error-related thalamic activity during early compared to late cocaine abstinence
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519 USA
    Drug Alcohol Depend 109:181-9. 2010
    ..These findings support the hypothesis that heightened thalamic reactivity to salient stimuli co-occur with cocaine craving and loss of self control...
  42. pmc Coercive sexual experiences, protective behavioral strategies, alcohol expectancies and consumption among male and female college students
    Rebekka S Palmer
    Yale School of Medicine, Department of Psychiatry, 915 Old Oak Rd, Livermore, CA 94550, USA
    J Interpers Violence 25:1563-78. 2010
    ..Results suggest that campus alcohol and sexual assault prevention efforts should include information on alcohol expectancies and use of protective strategies...
  43. pmc Neuroscience of behavioral and pharmacological treatments for addictions
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuron 69:695-712. 2011
    ..We then propose new directions for treatment development and targets that are informed by recent evidence regarding the heterogeneity of addictions and the neurobiological contributions to these disorders...
  44. pmc Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 107:221-9. 2010
    ..It was hypothesized that different treatments may affect different trajectories of drinking...
  45. pmc Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Subst Abus 30:306-17. 2009
    ..This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress...
  46. pmc Allopathic, complementary, and alternative medical treatment utilization for pain among methadone-maintained patients
    Declan T Barry
    Yale University School of Medicine, CMHC SAC Room 220, 34 Park Street, New Haven CT 06519 1187, USA
    Am J Addict 18:379-85. 2009
    ..These findings may have implications for resource and program planning in MMTPs...
  47. pmc D-Cycloserine attenuates reactivity to smoking cues in nicotine dependent smokers: a pilot investigation
    Elizabeth J Santa Ana
    VA Connecticut Healthcare System, Department of Psychiatry, Division of Substance Abuse, West Haven, CT 06516, USA
    Drug Alcohol Depend 104:220-7. 2009
    ..These findings provide promising support for DCS combined with cue exposure therapy in attenuating conditioned reactivity to smoking cues...
  48. pmc A treatment for substance abusing pregnant women
    Kimberly Ann Yonkers
    Perinatal Research Program, Department of Psychiatry, Yale University School of Medicine, 142 Temple Street, New Haven, CT 06510, USA
    Arch Womens Ment Health 12:221-7. 2009
    ..Treatment fidelity was assessed using the Yale Adherence and Competence System. Behavioral treatment delivery in this setting is feasible and is being evaluated in a randomized, controlled, clinical trial...
  49. pmc Cognitive function and treatment response in a randomized clinical trial of computer-based training in cognitive-behavioral therapy
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Subst Use Misuse 46:23-34. 2011
    ..Those with higher levels of risk taking completed fewer sessions and homework assignments and had poorer substance use outcomes...
  50. ncbi request reprint A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders
    Steve Martino
    Yale Psychosocial Substance Abuse Research Center and Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 101:1479-92. 2006
    ..This pilot study examined the efficacy of a two-session motivational interview adapted for dually diagnosed psychotic and drug-related disordered patients (DDMI) in comparison to a two-session standard psychiatric interview (SI)...
  51. ncbi request reprint Gambling urges in pathological gambling: a functional magnetic resonance imaging study
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    Arch Gen Psychiatry 60:828-36. 2003
    ..An improved understanding of the neural correlates of gambling urges in PG would advance our understanding of the brain mechanisms underlying PG and would help direct research into effective treatments...
  52. ncbi request reprint Personality, drug of choice, and comorbid psychopathology among substance abusers
    Kevin P Conway
    Departments of Epidemiology and Public Health, Yale University School of Medicine, 40 Temple Street, Suite 7B, New Haven, CT 06510, USA
    Drug Alcohol Depend 65:225-34. 2002
    ....
  53. pmc Choosing a behavioral therapy platform for pharmacotherapy of substance users
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, VA CT Healthcare Center, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 75:123-34. 2004
    ..Available manualized behavioral treatments are reviewed, noting their strengths and limitations as behavioral therapy platforms for pharmacotherapy trials and as potential concomitant therapies in clinical practice...
  54. pmc Sex differences in cocaine-dependent individuals' response to disulfiram treatment
    Charla Nich
    Yale University School of Medicine, VA Connecticut Health Care System, West Haven, USA
    Addict Behav 29:1123-8. 2004
    ..Reasons for this apparent sex-based response are not clear, but possible mechanisms worthy of greater study include differences in alcohol use by sex as well as differences in dopamine-mediated responses to cocaine and disulfiram...
  55. ncbi request reprint Contingency management to enhance naltrexone treatment of opioid dependence: a randomized clinical trial of reinforcement magnitude
    Kathleen M Carroll
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Exp Clin Psychopharmacol 10:54-63. 2002
    ..These findings suggest that targeted behavioral therapies can play a substantial role in broadening the utility of available pharmacotherapies...
  56. pmc Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Arch Gen Psychiatry 61:264-72. 2004
    ..Disulfiram has emerged as a promising treatment for cocaine dependence, but it has not yet been evaluated in general populations of cocaine users...
  57. ncbi request reprint Sex differences in depressed substance abusers
    Rajita Sinha
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn 06519, USA
    J Clin Psychiatry 63:616-27. 2002
    ..The second goal is to make recommendations for future research in the area of gender-specific aspects of comorbid depression and substance abuse...
  58. ncbi request reprint Initial and maintenance naltrexone treatment for alcohol dependence using primary care vs specialty care: a nested sequence of 3 randomized trials
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Arch Intern Med 163:1695-704. 2003
    ..This study tests naltrexone and primary care management (PCM) vs naltrexone and cognitive behavior therapy (CBT) and tests naltrexone maintenance among patients who respond to an initial course of naltrexone combined with PCM vs CBT...
  59. ncbi request reprint Substance abuse and fathering: adding poppa to the research agenda
    Thomas J McMahon
    Yale University School of Medicine, Department of Psychiatry, Division of Substance Abuse, New Haven, USA
    Addiction 97:1109-15. 2002
    ....
  60. pmc Bridging the gap: a hybrid model to link efficacy and effectiveness research in substance abuse treatment
    Kathleen M Carroll
    Department of Psychiatry at Yale University School of Medicine, West Haven, Connecticut, USA
    Psychiatr Serv 54:333-9. 2003
    ..Such issues include diversity in settings, clinicians, and patients; cost-effectiveness of treatment; training issues; and patient and clinician satisfaction...
  61. pmc Millon Clinical Multiaxial Inventory-III subtypes of opioid dependence: validity and matching to behavioral therapies
    Samuel A Ball
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Consult Clin Psychol 72:698-711. 2004
    ..Predictive validity analyses indicated less symptom improvement for the higher problem subtypes, and patient treatment matching analyses indicated that some subtypes had better outcomes in the no-incentive voucher conditions...
  62. pmc Gambling: an addictive behavior with health and primary care implications
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT 06519, USA
    J Gen Intern Med 17:721-32. 2002
    ....
  63. ncbi request reprint Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes
    Rajita Sinha
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn 06519, USA
    Arch Gen Psychiatry 63:324-31. 2006
    ..Stress and drug cue exposure are known to increase cocaine craving and stress arousal, but the association between these responses and cocaine relapse has not been previously studied...
  64. ncbi request reprint A cognitive behavioral therapy for alcohol-dependent domestic violence offenders: an integrated substance abuse-domestic violence treatment approach (SADV)
    Caroline J Easton
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine SATU, 1 Long Wharf, New Haven, CT 06511, USA
    Am J Addict 16:24-31. 2007
    ..These data suggest the promise of the SADV group therapy approach for alcohol-dependent males with a history of IPV who present for substance abuse treatment...
  65. ncbi request reprint Characteristics of tobacco-smoking problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Addict 13:471-93. 2004
    ..The high proportion of callers reporting daily tobacco smoking highlights the need for enhanced smoking cessation efforts in problem gamblers...
  66. ncbi request reprint Looking for poppa: parenting status of men versus women seeking drug abuse treatment
    Thomas J McMahon
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Am J Drug Alcohol Abuse 31:79-91. 2005
    ..There were no significant gender differences in the number of children or the average age of children. The results suggested that fathering may be an important, but largely neglected, treatment issue for drug-abusing men...
  67. ncbi request reprint Reasons for dropout from drug abuse treatment: symptoms, personality, and motivation
    Samuel A Ball
    Yale University School of Medicine, Department of Psychiatry, Division of Substance Abuse, United States VA Connecticut Healthcare System, West Haven, CT 06516, United States
    Addict Behav 31:320-30. 2006
    ..Results from this preliminary evaluation will guide the development of an instrument and intervention focused on dropout risk factors and treatment reengagement...
  68. ncbi request reprint Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study
    Rajita Sinha
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, Room S110, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 183:171-80. 2005
    ..Identifying neural activity associated with stress and stress-induced cocaine craving is important in understanding the neurobiology of cocaine craving and relapse...
  69. ncbi request reprint Rates of personality disorders in substance abusers: a comparison between DSM-III-R and DSM-IV
    J Poling
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    J Pers Disord 13:375-84. 1999
    ..Poor rates of diagnostic agreement were obtained for the histrionic and dependent diagnostic categories. No single diagnostic change appears to be responsible for the prevalence rate differences between the two systems...
  70. ncbi request reprint A placebo controlled trial of bupropion for smoking cessation in schizophrenia
    Tony P George
    Program for Research in Smokers with Mental Illness and Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 52:53-61. 2002
    ..We compared sustained-release (SR) bupropion with placebo for smoking cessation in patients with schizophrenic disorders. We also examined how antipsychotic class predicts smoking cessation outcomes with bupropion...
  71. ncbi request reprint Motivational interviewing with psychiatrically ill substance abusing patients
    S Martino
    Yale University School of Medicine, New Haven, Conn 06520 8038, USA
    Am J Addict 9:88-91. 2000
    ....
  72. ncbi request reprint Nicotine transdermal patch and atypical antipsychotic medications for smoking cessation in schizophrenia
    T P George
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Center, New Haven, CT 06519, USA
    Am J Psychiatry 157:1835-42. 2000
    ....
  73. pmc Cue-dose training with monetary reinforcement: pilot study of an antiretroviral adherence intervention
    M O Rigsby
    Medical Service, Department of Veterans Affairs Connecticut Healthcare System, West Haven, Conn 06516, USA
    J Gen Intern Med 15:841-7. 2000
    ..To assess the feasibility and efficacy of two interventions for improving adherence to antiretroviral therapy regimens in HIV-infected subjects compared with a control intervention...
  74. ncbi request reprint Functional magnetic resonance imaging of cocaine craving
    B E Wexler
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Psychiatry 158:86-95. 2001
    ..Identification of brain activity associated with craving is important for understanding the neurobiology of addiction...
  75. pmc On beyond urine: clinically useful assessment instruments in the treatment of drug dependence
    K M Carroll
    Division of Substance Abuse, VA CT Healthcare Center 151D, West Haven, CT 06516, USA
    Behav Res Ther 40:1329-44. 2002
    ..Progress in the field of drug abuse treatment has been significantly hampered by the failure to adopt, across research and clinical settings, a common set of assessments...
  76. ncbi request reprint Familial transmission of substance use disorders
    K R Merikangas
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn 06510, USA
    Arch Gen Psychiatry 55:973-9. 1998
    ..To perform a controlled family study of probands with several different predominant drugs of abuse, including opioids, cocaine, cannabis, and/or alcohol...
  77. pmc White matter integrity is associated with treatment outcome measures in cocaine dependence
    Jiansong Xu
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Neuropsychopharmacology 35:1541-9. 2010
    ..The findings of an association between better WM integrity at treatment onset and longer abstinence suggest that strategies for improving WM integrity warrant consideration in developing new interventions for cocaine dependence...
  78. pmc We don't train in vain: a dissemination trial of three strategies of training clinicians in cognitive-behavioral therapy
    Diane E Sholomskas
    Applied Behavioral Research, New Haven, CT, USA
    J Consult Clin Psychol 73:106-15. 2005
    ..Statistically significant differences favoring the seminar plus supervision over the manual only condition were found for adherence and skill ratings for 2 of the 3 role plays, with intermediate scores for the Web condition...
  79. ncbi request reprint Are personality traits familial risk factors for substance use disorders? Results of a controlled family study
    Joel D Swendsen
    Department of Psychology, University of Bordeaux, Bordeaux, France
    Am J Psychiatry 159:1760-6. 2002
    ..In this investigation the authors examined one such explanation, that certain personality traits are familial risk factors for the development of substance abuse or dependence...
  80. ncbi request reprint Errors in assessing DSM-IV substance use disorders
    Bridget F Grant
    Arch Gen Psychiatry 64:379-80; author reply 381-2. 2007
  81. pmc Contingency Management to reduce substance use in individuals who are homeless with co-occurring psychiatric disorders
    Kathlene Tracy
    New York University School of Medicine, New York, NY 10032, USA
    Am J Drug Alcohol Abuse 33:253-8. 2007
    ..This pilot trial suggests that application of low-cost CM procedures is feasible within this novel setting and may decrease substance use...
  82. ncbi request reprint Preliminary validity and reliability testing of a structured clinical interview for pathological gambling
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Psychiatry Res 128:79-88. 2004
    ..The SCI-PG demonstrated excellent reliability and validity in diagnosing PG in subjects presenting with gambling problems. These findings require replication in other groups to examine their generalizability...
  83. ncbi request reprint Treatment of patients with substance use disorders, second edition. American Psychiatric Association
    Herbert D Kleber
    Am J Psychiatry 164:5-123. 2007
  84. pmc Cost effectiveness of disulfiram: treating cocaine use in methadone-maintained patients
    Mireia Jofre-Bonet
    ICEH London School of Hygiene and Tropical Medicine, Keppel Street, Room 9 311, London WC1E 7HT, UK
    J Subst Abuse Treat 26:225-32. 2004
    ....
  85. pmc Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom?
    Nancy M Petry
    University of Connecticut Health Center, Farmington, CT, USA
    Addiction 99:349-60. 2004
    ..This study evaluated the efficacy of a low-cost, prize reinforcement contingency management (CM) intervention for reducing cocaine use...
  86. ncbi request reprint Personality, substance of choice, and polysubstance involvement among substance dependent patients
    Kevin P Conway
    Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, 6001 Executive Boulevard Suite 5153 MSC 9589, Bethesda, MD 20892 9589, USA
    Drug Alcohol Depend 71:65-75. 2003
    ..Findings implicate an association between behavioral disinhibition and a continuum of addiction defined primarily in terms of polysubstance involvement...
  87. ncbi request reprint Comorbidity of substance use with depression and other mental disorders: from Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) to DSM-V
    Edward V Nunes
    New York State Psychiatric Institute and Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA
    Addiction 101:89-96. 2006
    ..To arrive at recommendations for addressing co-occurring psychiatric and substance use disorders in the development of the Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-V) criteria...
  88. ncbi request reprint Treatment of patients with substance use disorders, second edition. American Psychiatic Association
    Herbert D Kleber
    Am J Psychiatry 163:5-82. 2006

Research Grants5

  1. Diagnosis & Treatment of Substance Use Disorder
    Bruce Rounsaville; Fiscal Year: 2007
    ..Secondary outcomes will include reductions in illicit opioid use and alcohol use, as well as improvements in psychosocial functioning. ..
  2. Clinician Scientist Training in Substance Abuse Research
    Bruce Rounsaville; Fiscal Year: 2007
    ..Since the onset of the program we have provided training for 22 Clinician Scientists, many of whom are among the leaders of their generation of drug abuse investigators. ..