Ken Pugh

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint A neurocognitive overview of reading acquisition and dyslexia across languages
    Ken Pugh
    Department of Pediatrics, Yale School of Medicine and Haskins Laboratories, New Haven, CT 06511, USA
    Dev Sci 9:448-50; discussion 451-3. 2006
  2. pmc The relationship between phonological and auditory processing and brain organization in beginning readers
    Kenneth R Pugh
    Haskins Laboratories, New Haven, CT, United States Yale University, School of Medicine, Department of Diagnostic Radiology, United States University of Connecticut, Department of Psychology, United States Electronic address
    Brain Lang 125:173-83. 2013
  3. pmc Effects of stimulus difficulty and repetition on printed word identification: an fMRI comparison of nonimpaired and reading-disabled adolescent cohorts
    Kenneth R Pugh
    Haskins Laboratories, New Haven, CT 06511, USA
    J Cogn Neurosci 20:1146-60. 2008
  4. ncbi request reprint Predicting reading performance from neuroimaging profiles: the cerebral basis of phonological effects in printed word identification
    K R Pugh
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510 8064, USA
    J Exp Psychol Hum Percept Perform 23:299-318. 1997
  5. ncbi request reprint Nicotine effects on brain function and functional connectivity in schizophrenia
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, 100 York Street 28, West Haven, CT 06511, USA
    Biol Psychiatry 55:850-8. 2004
  6. pmc Functional connectivity to a right hemisphere language center in prematurely born adolescents
    Eliza H Myers
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Neuroimage 51:1445-52. 2010
  7. doi request reprint Reading differences and brain: cortical integration of speech and print in sentence processing varies with reader skill
    Donald Shankweiler
    Haskins Laboratories, Department of Psychology, University of Connecticut, New Haven, CT 06511, USA
    Dev Neuropsychol 33:745-75. 2008
  8. ncbi request reprint Behavioral and neurobiological effects of printed word repetition in lexical decision and naming
    Leonard Katz
    Haskins Laboratories, New Haven, CT, USA
    Neuropsychologia 43:2068-83. 2005
  9. pmc Alterations in functional connectivity for language in prematurely born adolescents
    Robin J Schafer
    Department of Diagnostic Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, PO Box 208043, New Haven, CT 06520, USA
    Brain 132:661-70. 2009
  10. ncbi request reprint Impact of smoking abstinence on working memory neurocircuitry in adolescent daily tobacco smokers
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, 2 Church Street South, Suite 207, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 193:557-66. 2007

Research Grants

Detail Information

Publications27

  1. ncbi request reprint A neurocognitive overview of reading acquisition and dyslexia across languages
    Ken Pugh
    Department of Pediatrics, Yale School of Medicine and Haskins Laboratories, New Haven, CT 06511, USA
    Dev Sci 9:448-50; discussion 451-3. 2006
  2. pmc The relationship between phonological and auditory processing and brain organization in beginning readers
    Kenneth R Pugh
    Haskins Laboratories, New Haven, CT, United States Yale University, School of Medicine, Department of Diagnostic Radiology, United States University of Connecticut, Department of Psychology, United States Electronic address
    Brain Lang 125:173-83. 2013
    ..Implications for brain-based models of literacy acquisition are discussed...
  3. pmc Effects of stimulus difficulty and repetition on printed word identification: an fMRI comparison of nonimpaired and reading-disabled adolescent cohorts
    Kenneth R Pugh
    Haskins Laboratories, New Haven, CT 06511, USA
    J Cogn Neurosci 20:1146-60. 2008
    ..For RD readers, facilitative factors resulted in increased activation in these same reading-related sites, suggesting that the LH reading circuitry in adolescent RD is poorly trained but not wholly disrupted...
  4. ncbi request reprint Predicting reading performance from neuroimaging profiles: the cerebral basis of phonological effects in printed word identification
    K R Pugh
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510 8064, USA
    J Exp Psychol Hum Percept Perform 23:299-318. 1997
    ....
  5. ncbi request reprint Nicotine effects on brain function and functional connectivity in schizophrenia
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, 100 York Street 28, West Haven, CT 06511, USA
    Biol Psychiatry 55:850-8. 2004
    ..Our primary aim was to determine whether nicotine improves cognitive function by facilitating activation of brain regions mediating task performance or by facilitating functional connectivity...
  6. pmc Functional connectivity to a right hemisphere language center in prematurely born adolescents
    Eliza H Myers
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Neuroimage 51:1445-52. 2010
    ..439, p=0.019). Preterm adolescents engage a dorsal right hemisphere region for language at age 16years. Those with the greatest cognitive deficits demonstrate increasing reliance on this alternate pathway...
  7. doi request reprint Reading differences and brain: cortical integration of speech and print in sentence processing varies with reader skill
    Donald Shankweiler
    Haskins Laboratories, Department of Psychology, University of Connecticut, New Haven, CT 06511, USA
    Dev Neuropsychol 33:745-75. 2008
    ..The findings provide new evidence of the role of the inferior frontal region in supporting supramodal systems of linguistic representation...
  8. ncbi request reprint Behavioral and neurobiological effects of printed word repetition in lexical decision and naming
    Leonard Katz
    Haskins Laboratories, New Haven, CT, USA
    Neuropsychologia 43:2068-83. 2005
    ....
  9. pmc Alterations in functional connectivity for language in prematurely born adolescents
    Robin J Schafer
    Department of Diagnostic Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, PO Box 208043, New Haven, CT 06520, USA
    Brain 132:661-70. 2009
    ..Plasticity in network connections may provide the substrate for improving language skills in the prematurely born...
  10. ncbi request reprint Impact of smoking abstinence on working memory neurocircuitry in adolescent daily tobacco smokers
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, 2 Church Street South, Suite 207, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 193:557-66. 2007
    ..Work in rodents has shown that exposure to nicotine during adolescence leads to nicotine withdrawal emergent alterations in cortical and subcortical dopamine neurotransmission...
  11. pmc Phonological awareness predicts activation patterns for print and speech
    Stephen J Frost
    Haskins Laboratories, 300 George Street, New Haven, CT 06511, USA
    Ann Dyslexia 59:78-97. 2009
    ....
  12. pmc An fMRI study of multimodal semantic and phonological processing in reading disabled adolescents
    Nicole Landi
    Child Study Center, Yale University School of Medicine, 230 S Frontage, New Haven, CT 06520, USA
    Ann Dyslexia 60:102-21. 2010
    ..These findings indicate a neurobiological marker in RD that is independent of task, modality, or performance. These findings are discussed in the context of current neurobiological models of RD...
  13. pmc Unification of sentence processing via ear and eye: an fMRI study
    David Braze
    Haskins Laboratories, 300 George Street, New Haven, Connecticut 06511, USA
    Cortex 47:416-31. 2011
    ..Voxel-by-voxel exploration over the whole brain based on a cosine similarity measure of common function confirmed the specificity of supramodal zones...
  14. pmc Early and late talkers: school-age language, literacy and neurolinguistic differences
    Jonathan L Preston
    Haskins Laboratories, 300 George St, Suite 900, New Haven, CT 06511, USA
    Brain 133:2185-95. 2010
    ....
  15. ncbi request reprint Gender-specific effects of prenatal and adolescent exposure to tobacco smoke on auditory and visual attention
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuropsychopharmacology 32:2453-64. 2007
    ....
  16. ncbi request reprint Functional correlates of verbal memory deficits emerging during nicotine withdrawal in abstinent adolescent cannabis users
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, Connecticut 06519, USA
    Biol Psychiatry 61:31-40. 2007
    ..Human studies have shown that both cannabis and tobacco exert effects on cognitive function; however, little is known about possible interacting effects of these drugs on brain function and cognition during adolescent development...
  17. ncbi request reprint C957T polymorphism of the dopamine D2 receptor gene modulates the effect of nicotine on working memory performance and cortical processing efficiency
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 188:530-40. 2006
    ....
  18. ncbi request reprint Sentence complexity and input modality effects in sentence comprehension: an fMRI study
    R Todd Constable
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520 8042, USA
    Neuroimage 22:11-21. 2004
    ..These sites showing modulation of activity as a function of sentence type, independent of input mode, arguably form the core of a cortical system essential to sentence parsing...
  19. ncbi request reprint Impact of cannabis use on brain function in adolescents
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Ann N Y Acad Sci 1021:384-90. 2004
    ..This paper reports results of a pilot study using fMRI and a working memory task to compare brain function of adolescent cannabis users to that of two control groups, one matched for tobacco use and the other for nonsmokers...
  20. ncbi request reprint The neurobiology of adaptive learning in reading: a contrast of different training conditions
    Rebecca Sandak
    Haskins Laboratories, New Haven, Connecticut 06511 6695, USA
    Cogn Affect Behav Neurosci 4:67-88. 2004
    ..The findings indicate that the putative ventral visual word form area is sensitive to the phonological structure of words, with phonologically analytic processing contributing to the specialization of this region...
  21. ncbi request reprint Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, 100 York Street 2B, New Haven, CT 06511, USA
    Biol Psychiatry 57:56-66. 2005
    ..We tested for evidence of acute and chronic effects of tobacco smoking on cognition in adolescents who smoked tobacco daily and were compared with adolescent nonsmokers...
  22. ncbi request reprint A functional magnetic resonance imaging study of the tradeoff between semantics and phonology in reading aloud
    Stephen J Frost
    Haskins Laboratories, Yale University School of Medicine, New Haven, Connecticut, USA
    Neuroreport 16:621-4. 2005
    ....
  23. ncbi request reprint Visuospatial memory deficits emerging during nicotine withdrawal in adolescents with prenatal exposure to active maternal smoking
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuropsychopharmacology 31:1550-61. 2006
    ....
  24. ncbi request reprint Preliminary evidence of hippocampal dysfunction in adolescent MDMA ("ecstasy") users: possible relationship to neurotoxic effects
    Leslie K Jacobsen
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn 06511, USA
    Psychopharmacology (Berl) 173:383-90. 2004
    ..Although cognitive deficits among adult MDMA users are well documented, little is known of the cognitive and brain functional sequelae of MDMA use during adolescence...
  25. ncbi request reprint Development of left occipitotemporal systems for skilled reading in children after a phonologically- based intervention
    Bennett A Shaywitz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510 8064, USA
    Biol Psychiatry 55:926-33. 2004
    ..In this study, we hypothesized that the provision of an evidence-based, phonologically mediated reading intervention would improve reading fluency and the development of the fast-paced occipitotemporal systems serving skilled reading...
  26. ncbi request reprint Neural systems for compensation and persistence: young adult outcome of childhood reading disability
    Sally E Shaywitz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510 8064, USA
    Biol Psychiatry 54:25-33. 2003
    ....
  27. ncbi request reprint Disruption of posterior brain systems for reading in children with developmental dyslexia
    Bennett A Shaywitz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510 8064, USA
    Biol Psychiatry 52:101-10. 2002
    ..e., tapped the problems experienced by dyslexic children in sounding out words)...

Research Grants12

  1. COGNITIVE & NEUROBIOL MECHANISMS IN READING DISABILITY
    Kenneth Pugh; Fiscal Year: 2005
    ....
  2. Neurobiological Foundations of reading (dis)ability
    Kenneth Pugh; Fiscal Year: 2009
    ....
  3. Neurobiological Foundations of reading (dis)ability
    Kenneth R Pugh; Fiscal Year: 2010
    ....