MARC POTENZA

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Advances in the pharmacological treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    J Gambl Stud 19:85-109. 2003
  2. ncbi Serotonin 1B receptor imaging in pathological gambling
    Marc N Potenza
    Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    World J Biol Psychiatry 14:139-45. 2013
  3. ncbi Neural Correlates of Stress- and Food Cue-Induced Food Craving in Obesity: Association with insulin levels
    Ania M Jastreboff
    Corresponding author Marc N Potenza
    Diabetes Care 36:394-402. 2013
  4. ncbi Characteristics of older adult problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 22:241-54. 2006
  5. ncbi Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence
    Marc N Potenza
    Yale Unive rsity Schoolof Medicine, New Haven, Conn, USA
    Am J Psychiatry 169:406-14. 2012
  6. ncbi Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    Philos Trans R Soc Lond B Biol Sci 363:3181-9. 2008
  7. ncbi Characteristics of tobacco-smoking problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Addict 13:471-93. 2004
  8. ncbi Advancing treatment strategies for pathological gambling
    Marc N Potenza
    Connecticut Mental Health Center, Problem Gambling Clinic, Women s Health Research at Yale, Yale University School of Medicine, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 21:91-100. 2005
  9. ncbi A gender-based examination of past-year recreational gamblers
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT, USA
    J Gambl Stud 22:41-64. 2006
  10. ncbi Should addictive disorders include non-substance-related conditions?
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT, USA
    Addiction 101:142-51. 2006

Research Grants

  1. fMRI of CBT and CM for Cocaine Dependence
    MARC POTENZA; Fiscal Year: 2009
  2. fMRI of Craving in Addictions: Gender Differences
    MARC POTENZA; Fiscal Year: 2009
  3. Selegiline for Smoking Cessation
    MARC POTENZA; Fiscal Year: 2007

Detail Information

Publications93

  1. ncbi Advances in the pharmacological treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454 1495, USA
    J Gambl Stud 19:85-109. 2003
    ..We also discuss dosage strategies, the duration of treatment, issues surrounding medication compliance, and approaches to treatment-refractory pathological gambling, such as pharmacological and behavioral augmentation...
  2. ncbi Serotonin 1B receptor imaging in pathological gambling
    Marc N Potenza
    Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    World J Biol Psychiatry 14:139-45. 2013
    ....
  3. ncbi Neural Correlates of Stress- and Food Cue-Induced Food Craving in Obesity: Association with insulin levels
    Ania M Jastreboff
    Corresponding author Marc N Potenza
    Diabetes Care 36:394-402. 2013
    ..Improving insulin sensitivity and in turn reducing corticolimbic-striatal reactivity to food cues and stress may diminish food craving and affect eating behavior in obesity...
  4. ncbi Characteristics of older adult problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 22:241-54. 2006
    ..Given data from older adult problem gamblers in treatment, we hypothesized that older as compared with younger adult problem gamblers calling a gambling helpline would be less likely to report gambling-related problems...
  5. ncbi Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence
    Marc N Potenza
    Yale Unive rsity Schoolof Medicine, New Haven, Conn, USA
    Am J Psychiatry 169:406-14. 2012
    ....
  6. ncbi Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    Philos Trans R Soc Lond B Biol Sci 363:3181-9. 2008
    ..Implications for prevention and treatment strategies will be discussed...
  7. ncbi Characteristics of tobacco-smoking problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Addict 13:471-93. 2004
    ..The high proportion of callers reporting daily tobacco smoking highlights the need for enhanced smoking cessation efforts in problem gamblers...
  8. ncbi Advancing treatment strategies for pathological gambling
    Marc N Potenza
    Connecticut Mental Health Center, Problem Gambling Clinic, Women s Health Research at Yale, Yale University School of Medicine, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 21:91-100. 2005
    ..g., those with co-occurring alcohol use disorders) explored. Treatment for pathological gambling might be advanced most rapidly through collaborative multi-center efforts...
  9. ncbi A gender-based examination of past-year recreational gamblers
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT, USA
    J Gambl Stud 22:41-64. 2006
    ..Most adults gamble recreationally yet few studies have systematically investigated for gender-related differences in recreational gamblers...
  10. ncbi Should addictive disorders include non-substance-related conditions?
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT, USA
    Addiction 101:142-51. 2006
    ..In anticipation of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), to consider whether addictive disorders should include non-substance use disorders...
  11. ncbi Characteristics of gambling helpline callers with self-reported gambling and alcohol use problems
    Marc N Potenza
    Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 21:233-54. 2005
    ....
  12. ncbi Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuropsychopharmacology 33:2735-46. 2008
    ..These findings suggest that common genetic mechanisms influence certain biochemical and behavioral aspects of stimulant responsiveness...
  13. ncbi An FMRI Stroop task study of ventromedial prefrontal cortical function in pathological gamblers
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    Am J Psychiatry 160:1990-4. 2003
    ..The authors used the Stroop paradigm to test attention and response inhibition during the presentation of congruent and incongruent stimuli in male pathological gamblers and a group of comparison subjects...
  14. ncbi Shared genetic contributions to pathological gambling and major depression in men
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, New Haven, CT 06519, USA
    Arch Gen Psychiatry 62:1015-21. 2005
    ..Although pathological gambling (PG) and major depression (MD) frequently co-occur, little is known regarding the relative contributions of environmental and genetic factors to the codevelopment of the disorders...
  15. ncbi The neurobiology of pathological gambling
    M N Potenza
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Semin Clin Neuropsychiatry 6:217-26. 2001
    ....
  16. ncbi Gender-related differences in the characteristics of problem gamblers using a gambling helpline
    M N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven 06519, USA
    Am J Psychiatry 158:1500-5. 2001
    ..The characteristics of male and female gamblers utilizing a gambling helpline were examined to identify gender-related differences...
  17. ncbi Drug Insight: impulse control disorders and dopamine therapies in Parkinson's disease
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Nat Clin Pract Neurol 3:664-72. 2007
    ....
  18. ncbi The neurobiology of pathological gambling: translating research findings into clinical advances
    Marc N Potenza
    Yale University School of Medicine, USA
    J Gambl Stud 19:7-10. 2003
  19. ncbi Illegal behaviors in problem gambling: analysis of data from a gambling helpline
    M N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    J Am Acad Psychiatry Law 28:389-403. 2000
    ..The results of the present study highlight the importance of the identification and treatment of individuals with gambling problems with respect to legal issues...
  20. ncbi Neuroscience of behavioral and pharmacological treatments for addictions
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuron 69:695-712. 2011
    ..We then propose new directions for treatment development and targets that are informed by recent evidence regarding the heterogeneity of addictions and the neurobiological contributions to these disorders...
  21. ncbi Correlates of at-risk/problem internet gambling in adolescents
    Marc N Potenza
    Yale School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    J Am Acad Child Adolesc Psychiatry 50:150-159.e3. 2011
    ..However, relatively few studies have examined Internet gambling in adolescents. This study sought to investigate the correlates of at-risk or problem gambling in adolescents acknowledging or denying gambling on the Internet...
  22. ncbi Gambling urges in pathological gambling: a functional magnetic resonance imaging study
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    Arch Gen Psychiatry 60:828-36. 2003
    ..An improved understanding of the neural correlates of gambling urges in PG would advance our understanding of the brain mechanisms underlying PG and would help direct research into effective treatments...
  23. ncbi Psychiatric correlates of gambling in adolescents and young adults grouped by age at gambling onset
    Wendy J Lynch
    Women and Addictive Disorders Core of Women's Health Research and the Division of Substance Abuse of the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    Arch Gen Psychiatry 61:1116-22. 2004
    ..More research is needed to investigate the relationships and inform prevention and treatment strategies...
  24. ncbi Relationship of nicotine dependence, subsyndromal and pathological gambling, and other psychiatric disorders: data from the National Epidemiologic Survey on Alcohol and Related Conditions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 70:334-43. 2009
    ..Nicotine dependence frequently co-occurs with subsyndromal and pathological levels of gambling. The relationship of nicotine dependence, levels of gambling pathology, and other psychiatric disorders, however, is incompletely understood...
  25. ncbi Excitement-seeking gambling in a nationally representative sample of recreational gamblers
    Michael V Pantalon
    Department of Psychiatry Division of Substance Abuse, Yale University, 34 Park Street, Room S 104, New Haven, CN 06519, USA
    J Gambl Stud 24:63-78. 2008
    ..e., at-risk gambling). Together, these findings indicate that EGs are more likely than NEGs to demonstrate problems in multiple areas characterized by impaired impulse control...
  26. ncbi The neurobiology and genetics of impulse control disorders: relationships to drug addictions
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Biochem Pharmacol 75:63-75. 2008
    ..Here, we review the genetic and neuropathological bases of the impulse control disorders and consider the disorders within these non-mutually exclusive frameworks...
  27. ncbi Binge drinking in undergraduates: relationships with sex, drinking behaviors, impulsivity, and the perceived effects of alcohol
    Iris M Balodis
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, Connecticut, USA
    Behav Pharmacol 20:518-26. 2009
    ..These results have implications for sex-specific prevention strategies for binge drinking on university campuses...
  28. ncbi Sexual orientation of men with pathological gambling: prevalence and psychiatric comorbidity in a treatment-seeking sample
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Compr Psychiatry 47:515-8. 2006
    ..04). Psychiatric comorbidity and impairment are high in gay and bisexual men with PG. Research is needed to optimize patient care for gay and bisexual men with PG...
  29. ncbi The neurobiology of substance and behavioral addictions
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    CNS Spectr 11:924-30. 2006
    ....
  30. ncbi Predicting response to opiate antagonists and placebo in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Psychopharmacology (Berl) 200:521-7. 2008
    ..No studies have systematically examined predictors of medication treatment outcome in PG. Understanding clinical variables related to treatment outcome should help generate treatment algorithms for PG...
  31. ncbi Late-onset pathological gambling: clinical correlates and gender differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Psychiatr Res 43:380-7. 2009
    ..Late-onset PG is relatively common and has distinct clinical characteristics suggesting that this population might benefit from unique prevention and treatment strategies...
  32. ncbi Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:303-12. 2006
    ..The authors examined the efficacy and tolerability of the opioid antagonist nalmefene in the treatment of adults with pathological gambling...
  33. ncbi Gender differences in adolescent gambling
    Rani A Desai
    Department of Psychiatry and Women and Addictive Disorders Core of Women's Health Research, Yale University School of Medicine, New Haven, CT 06519, USA
    Ann Clin Psychiatry 17:249-58. 2005
    ..Gender considerations are important in understanding youth gambling and the relationship between gambling and psychiatric disorders in adolescents...
  34. ncbi [The neurobiology of impulse control disorders]
    Wendol A Williams
    Departamento de Psiquiatria, School of Medicine, Yale University, New Haven, Connecticut 06519, USA
    Rev Bras Psiquiatr 30:S24-30. 2008
    ..To review the neurobiological substrates of impulse control disorders. Pathological gambling is a main focus of the review in that most biological studies of the formal impulse control disorders have examined this disorder...
  35. ncbi A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder
    Rani A Desai
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    J Clin Psychiatry 70:1250-7. 2009
    ..However, gambling behaviors in large samples of patients with schizophrenia/schizoaffective disorder have not been systematically examined to date...
  36. ncbi Neurobiology of adolescent substance use disorders: implications for prevention and treatment
    Helena J V Rutherford
    Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA
    Child Adolesc Psychiatr Clin N Am 19:479-92. 2010
    ..First, the authors review the neurobiology of adolescent substance use disorders and, second, the authors consider the implications of these findings for prevention and treatment...
  37. ncbi Video-gaming among high school students: health correlates, gender differences, and problematic gaming
    Rani A Desai
    Department of Psychology, Yale University School of Medicine, West Haven, Connecticut, USA
    Pediatrics 126:e1414-24. 2010
    ..However, the existing literature on gaming is inconsistent and often has focused on aggression rather than the health correlates of gaming and the prevalence and correlates of problematic gaming...
  38. ncbi Differential associations between problem and pathological gambling and psychiatric disorders in individuals with and without alcohol abuse or dependence
    Judson A Brewer
    Yale Therapeutic Neuroscience Clinic, New Haven, CT, USA
    CNS Spectr 15:33-44. 2010
    ..However, prior studies have not investigated the relative influence of AUDs on the associations between PPG and other psychiatric disorders,..
  39. ncbi Differences in the associations between gambling problem severity and psychiatric disorders among black and white adults: findings from the National Epidemiologic Survey on Alcohol and Related Conditions
    Declan T Barry
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519 1187, USA
    Am J Addict 20:69-77. 2011
    ....
  40. ncbi Gambling, health and age: data from the National Epidemiologic Survey on Alcohol and Related Conditions
    Rani A Desai
    Yale University and Veteran s Affairs Connecticut Healthcare System, West Haven, CT 06516, USA
    Psychol Addict Behav 21:431-40. 2007
    ..g., obesity) but also with some positive measures (e.g., better physical and mental functioning). Longitudinal studies are needed to clarify the relationship between gambling and health in older adults in the context of healthy aging...
  41. ncbi Cognitive function and treatment response in a randomized clinical trial of computer-based training in cognitive-behavioral therapy
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Subst Use Misuse 46:23-34. 2011
    ..Those with higher levels of risk taking completed fewer sessions and homework assignments and had poorer substance use outcomes...
  42. ncbi Perceptual load-dependent neural correlates of distractor interference inhibition
    Jiansong Xu
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 6:e14552. 2011
    ..g., in the frontostriatal circuits) is also smaller at high rather than low perceptual load, as might be predicted based on the load theory...
  43. ncbi Behavioral and neurological foundations for the moral and legal implications of intoxication, addictive behaviors and disinhibition
    Robert F Leeman
    Yale University School of Medicine, Substance Abuse Center, CMHC, 34 Park Street, Room S200, New Haven, CT 06519, USA
    Behav Sci Law 27:237-59. 2009
    ..Such findings may have important implications in multiple legal and psychiatric domains...
  44. ncbi Pretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients
    Judson A Brewer
    Yale University School of Medicine, Department of Psychiatry, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Biol Psychiatry 64:998-1004. 2008
    ..No prior studies have systematically examined the neural correlates of cognitive control as related to treatment outcomes for cocaine dependence...
  45. ncbi Gender-related influences of parental alcoholism on the prevalence of psychiatric illnesses: analysis of the National Epidemiologic Survey on Alcohol and Related Conditions
    Peter T Morgan
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Alcohol Clin Exp Res 34:1759-67. 2010
    ..In this study, we tested the hypothesis that the gender of the parent with alcoholism and the gender of offspring affect the association between parental alcoholism and offspring psychiatric illness...
  46. ncbi Smoking expectancies, weight concerns, and dietary behaviors in adolescence
    Dana A Cavallo
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Pediatrics 126:e66-72. 2010
    ....
  47. ncbi Validation of the questionnaire for impulsive-compulsive disorders in Parkinson's disease
    Daniel Weintraub
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mov Disord 24:1461-7. 2009
    ..A positive screen should be followed by a comprehensive, clinical interview to determine the range and severity of symptoms, as well as need for clinical management...
  48. ncbi Risk/reward decision-making in schizophrenia: a preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance
    Sarah W Yip
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 2 Church Street South, Suite 215, New Haven, CT, United States
    Schizophr Res 110:156-64. 2009
    ..Studies of risk/reward decision-making in individuals with schizophrenia have yielded mixed results, and few studies have examined systematically the relationship between these domains and their relationship with clinical factors...
  49. ncbi Differences in characteristics of Asian American and white problem gamblers calling a gambling helpline
    Declan T Barry
    Department of Psychiatry, Women and Addictive Disorders Core of Women s Health Research, Yale University School of Medicine, New Haven, CT 06519, USA
    CNS Spectr 14:83-91. 2009
    ..The characteristics of Asian American and white problem gamblers using a gambling helpline were examined to identify race-related differences...
  50. ncbi The relationship between recreational gambling and substance abuse/dependence: data from a nationally representative sample
    Timothy Liu
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    Drug Alcohol Depend 100:164-8. 2009
    ..Although recreational gambling is prevalent and co-occurs with substance abuse/dependence, few studies have investigated the relationship between the two...
  51. ncbi Gender differences in the association between body mass index and psychopathology
    Rani A Desai
    Department of Psychiatry, Yale University, New Haven, CT 06516, USA
    CNS Spectr 14:372-83. 2009
    ..The objective of the study was to examine gender differences in the relationship between weight group (under-weight to severely obese), and Axis I and Axis II psychopathology...
  52. ncbi Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Subst Abus 30:306-17. 2009
    ..This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress...
  53. ncbi Characteristics of black and white callers to a gambling helpline
    Declan T Barry
    Department of Psychiatry, Yale University School of Medicine, CMHC SAC, New Haven, CT 06519, USA
    Psychiatr Serv 59:1347-50. 2008
    ..Characteristics of black and white callers to a gambling helpline for southern New England were examined for racial differences...
  54. ncbi Mindfulness-based treatments for co-occurring depression and substance use disorders: what can we learn from the brain?
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Addiction 105:1698-706. 2010
    ..Finally, we discuss how advances in our understanding of potential mechanisms of mindfulness training may offer not only unique effects on depression and substance use, but also offer promise for treatment of co-occurring disorders...
  55. ncbi Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    J Clin Psychiatry 68:1584-92. 2007
    ..To examine in a sex-sensitive manner the frequencies, clinical correlates, and patterns of co-occurrence of impulse-control disorders in adolescent psychiatric inpatients...
  56. ncbi Self-perception of gambling problems among adolescents identified as at-risk or problem gamblers
    Jessica M Cronce
    Department of Psychology, Yale University, P O Box 208205, New Haven, CT 06520 8205, USA
    J Gambl Stud 23:363-75. 2007
    ..To advance prevention and treatment strategies, the apparent discrepancy between adolescents' self-perceptions and objective reports of problem gambling behaviors warrants further investigation...
  57. ncbi Cue-induced brain activity changes and relapse in cocaine-dependent patients
    Thomas R Kosten
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 31:644-50. 2006
    ..This physiological activation was a better predictor of relapse than subjective reports of craving, and may be a useful target for treatment development...
  58. ncbi Behavioral impulsivity predicts treatment outcome in a smoking cessation program for adolescent smokers
    Suchitra Krishnan-Sarin
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 34 Park Street, New Haven, CT 06519, USA
    Drug Alcohol Depend 88:79-82. 2007
    ..To examine the relationship between impulsivity and smoking cessation treatment response among adolescents...
  59. ncbi Gender differences in the associations between past-year gambling problems and psychiatric disorders
    Rani A Desai
    Dept of Psychiatry and Women and Addictive Disorders, Core of Women s Health Research, Yale University School of Medicine, New Haven, CT, USA
    Soc Psychiatry Psychiatr Epidemiol 43:173-83. 2008
    ..Psychiatric disorders frequently co-occur with pathological gambling. The extent to which co-occurence extends to subsyndromal levels of gambling or differs between women and men is incompletely understood...
  60. ncbi Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability
    R Andrew Chambers
    Connecticut Mental Health Center, the Problem Grambling Clinic, Yale University School of Medicine, New Haven, CT 06508, USA
    Am J Psychiatry 160:1041-52. 2003
    ..The authors describe basic and clinical data supporting adolescent neurodevelopment as a biologically critical period of greater vulnerability for experimentation with substances and acquisition of substance use disorders...
  61. ncbi Problematic Internet use: clinical implications
    Timothy Liu
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    CNS Spectr 12:453-66. 2007
    ..Clinicians should be familiar with the extent of problematic Internet use and the data regarding the efficacies and tolerabilities of available treatments...
  62. ncbi Self-reported gambling-related suicidality among gambling helpline callers
    David M Ledgerwood
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Psychol Addict Behav 19:175-83. 2005
    ..The findings suggest that increased gambling severity is associated with gambling-related suicidality...
  63. ncbi Gender differences among recreational gamblers: association with the frequency of alcohol use
    Rani A Desai
    Health Research and the Division of Substance Abuse of the Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychol Addict Behav 20:145-53. 2006
    ..There were few gender differences in the correlations between alcohol consumption and health. Future research should consider gender-related influences when examining alcohol use and gambling behaviors...
  64. ncbi Tobacco use and pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Ann Clin Psychiatry 17:237-41. 2005
    ..An improved understanding of the relationship would be helpful in treating individuals with co-occurring pathological gambling and nicotine dependence...
  65. ncbi Neurodevelopment, impulsivity, and adolescent gambling
    R Andrew Chambers
    Yale University School of Medicine, USA
    J Gambl Stud 19:53-84. 2003
    ..An exploration of the developmental changes in neural circuitry involved in impulse control has significant implications for understanding adolescent behaviors and treating problem and pathological gambling among youths...
  66. ncbi Perfusion abnormalities and decision making in cocaine dependence
    Karen A Tucker
    Department of Psychiatry, Yale University School of Medicine, New Haven, USA
    Biol Psychiatry 56:527-30. 2004
    ..This study examined whether cocaine-dependent patients have perfusion abnormalities associated with poor decision-making ability as measured by the Iowa Gambling Task (IGT)...
  67. ncbi Gambling: an addictive behavior with health and primary care implications
    Marc N Potenza
    Yale University School of Medicine, New Haven, CT 06519, USA
    J Gen Intern Med 17:721-32. 2002
    ....
  68. ncbi Health correlates of recreational gambling in older adults
    Rani A Desai
    Women and Addictive Disorders Core of Women s Health Research at Yale, Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, USA
    Am J Psychiatry 161:1672-9. 2004
    ..The objective of this study was to identify health and well-being correlates of past-year recreational gambling in adults age 65 years and older, compared to adults age 18-64 years...
  69. ncbi A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers
    Andrea H Weinberger
    Program for Research in Smokers with Mental Illness PRISM, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Drug Alcohol Depend 107:188-95. 2010
    ..The primary aim of this study was to determine the safety and efficacy of the monoamine oxidase-B (MAO-B) inhibitor selegiline hydrochloride (SEL, l-Deprenyl; Eldepryl) as an aid for smoking cessation in cigarette smokers...
  70. ncbi The Gambling Symptom Assessment Scale (G-SAS): a reliability and validity study
    Suck Won Kim
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Psychiatry Res 166:76-84. 2009
    ..The correlations between the G-SAS and the PG-YBOCS and Clinical Global Impression rating were excellent. Findings suggest that the G-SAS is reliable and valid in assessing changes in symptoms during a drug treatment study...
  71. ncbi Long-term follow-up of impulse control disorders in Parkinson's disease
    Eugenia Mamikonyan
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Mov Disord 23:75-80. 2008
    ....
  72. ncbi Impulse control disorders in adult psychiatric inpatients
    Jon E Grant
    Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55454
    Am J Psychiatry 162:2184-8. 2005
    ..The authors' goal was to examine the prevalence of impulse control disorders in psychiatric inpatients...
  73. ncbi Genetic studies of pathological gambling: a review of methodology and analyses of data from the Vietnam Era Twin Registry
    Kamini R Shah
    St Louis Veterans Affairs Medical Center, Washington University School of Medicine, 915 North Grand Boulevard, St Louis, MO 63106, USA
    J Gambl Stud 21:179-203. 2005
    ....
  74. ncbi Preliminary validity and reliability testing of a structured clinical interview for pathological gambling
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, 345 Blackstone Boulevard, Providence, RI 02906, USA
    Psychiatry Res 128:79-88. 2004
    ..The SCI-PG demonstrated excellent reliability and validity in diagnosing PG in subjects presenting with gambling problems. These findings require replication in other groups to examine their generalizability...
  75. ncbi A framework for reporting outcomes in problem gambling treatment research: the Banff, Alberta Consensus
    Michael Walker
    University of Sydney, Australia
    Addiction 101:504-11. 2006
    ..Such conditions will facilitate the development of empirically validated best practice guidelines for use by clinicians in the management of problem gambling...
  76. ncbi Gender-related differences in individuals seeking treatment for kleptomania
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    CNS Spectr 13:235-45. 2008
    ..Few empirical investigations have been performed in kleptomania, particularly with respect to gender-related influences...
  77. ncbi Commentary: illegal behavior and pathological gambling
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN, USA
    J Am Acad Psychiatry Law 35:302-5. 2007
    ..Although the article by Ledgerwood and colleagues provides additional insight into the relationship between pathological gambling and illegal behavior, many questions remain unanswered and warrant further investigation...
  78. ncbi Impulse control disorders: clinical characteristics and pharmacological management
    Jon E Grant
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, Rhode Island 02906, USA
    Ann Clin Psychiatry 16:27-34. 2004
    ....
  79. ncbi Association of dopamine agonist use with impulse control disorders in Parkinson disease
    Daniel Weintraub
    Department of Psychiatry, University of Pennsylvania, and Parkinson's Disease Research, Education, and Clinical Center, USA
    Arch Neurol 63:969-73. 2006
    ..Because dopamine agonists are increasingly being used for other indications, future research should assess the dopamine agonist-associated risk for ICDs in other populations...
  80. ncbi To do or not to do? The complexities of addiction, motivation, self-control, and impulsivity
    Marc N Potenza
    Am J Psychiatry 164:4-6. 2007
  81. ncbi Characteristics of adolescent past-year gamblers and non-gamblers in relation to alcohol drinking
    Amy M Duhig
    Indiana University Purdue University Indianapolis, IN, USA
    Addict Behav 32:80-9. 2007
    ..01). Among past-year gamblers, MHF drinkers were more likely than ALF ones to report frequent gambling. These results suggest a complex relationship between gambling alcohol use, drug use, and mental health in adolescents...
  82. ncbi A scale-free systems theory of motivation and addiction
    R Andrew Chambers
    Lab for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Indiana Division of Mental Health and Addiction, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
    Neurosci Biobehav Rev 31:1017-45. 2007
    ..This model may inform integrative research in defining more effective prevention and treatment strategies for addiction...
  83. ncbi Genomic regions controlling corticosterone levels in rats
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 55:634-41. 2004
    ..The identification of genetic factors controlling stress-responsiveness should advance the understanding of susceptibility to psychiatric illness...
  84. ncbi Simulated apoptosis/neurogenesis regulates learning and memory capabilities of adaptive neural networks
    R Andrew Chambers
    Division of Substance Abuse, Connecticut Mental Health Center, Yale University School of Medicine, USA
    Neuropsychopharmacology 29:747-58. 2004
    ..The implications of these elementary simulations for future biological and neural modeling research on apoptosis and neurogenesis are discussed...
  85. ncbi Paroxetine treatment of pathological gambling: a multi-centre randomized controlled trial
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55454 1495, USA
    Int Clin Psychopharmacol 18:243-9. 2003
    ..Paroxetine consistently demonstrated an advantage over placebo on the Clinical Global Impressions scale; however, a larger sample size may have registered significant differences...
  86. ncbi Compulsive aspects of impulse-control disorders
    Jon E Grant
    Department of Psychiatry, University of Minnesota Medical School, 2450 Riverside Avenue Minneapolis, MN 55454, USA
    Psychiatr Clin North Am 29:539-51, x. 2006
    ..The construct of compulsivity as related to ICDs and OCD warrants additional investigation to identify the similarities and differences and to examine the implications for prevention and treatment strategies...
  87. ncbi Escitalopram treatment of pathological gambling with co-occurring anxiety: an open-label pilot study with double-blind discontinuation
    Jon E Grant
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota 55454, USA
    Int Clin Psychopharmacol 21:203-9. 2006
    ..Larger, longer, placebo-controlled, double-blind studies are needed to evaluate further the safety and tolerability of escitalopram in the treatment of PG and co-occurring anxiety...
  88. ncbi Impulse control disorders in Parkinson's disease
    Daniel Weintraub
    Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Room 3003, Philadelphia, PA 19104, USA
    Curr Neurol Neurosci Rep 6:302-6. 2006
    ..As empirically validated treatments for ICDs are emerging, it will be important to examine their efficacy and tolerability in individuals with co-occurring PD and ICDs...
  89. ncbi Addicted to hair pulling? How an alternate model of trichotillomania may improve treatment outcome
    Jon E Grant
    Psychiatry Department, University of Minnesota Medical School, Minneapolis, MN 55454, USA
    Harv Rev Psychiatry 15:80-5. 2007
  90. ncbi Medication-related impulse control and repetitive behaviors in Parkinson's disease
    Valerie Voon
    Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, Maryland 20892 1428, USA
    Curr Opin Neurol 20:484-92. 2007
    ..In patients on dopamine agonists, these behaviors as a group are relatively common, can have potentially devastating psychosocial consequences and are commonly hidden...
  91. ncbi A placebo-controlled trial of bupropion combined with nicotine patch for smoking cessation in schizophrenia
    Tony P George
    Centre for Addiction and Mental Health, Faculty of Medicine, University of Toronto, Ontario, Canada
    Biol Psychiatry 63:1092-6. 2008
    ..We determined whether the combination of sustained-release (SR) bupropion (BUP) with the transdermal nicotine patch (TNP) was well-tolerated and superior to placebo (PLO)+TNP for smoking cessation in schizophrenia...
  92. ncbi Impulsivity and compulsivity in pathological gambling and obsessive-compulsive disorder
    Marc N Potenza
    Rev Bras Psiquiatr 29:105-6. 2007
  93. ncbi Acute tryptophan depletion in schizophrenic patients treated with clozapine
    Tony P George
    Arch Gen Psychiatry 59:291-2. 2002

Research Grants15

  1. fMRI of CBT and CM for Cocaine Dependence
    MARC POTENZA; Fiscal Year: 2009
    ..Successful completion of this project would lay the foundation for future studies (e.g., those combining behavioral and pharmacological treatments) in cocaine dependence and other addictive disorders. ..
  2. fMRI of Craving in Addictions: Gender Differences
    MARC POTENZA; Fiscal Year: 2009
    ..abstract_text> ..
  3. Selegiline for Smoking Cessation
    MARC POTENZA; Fiscal Year: 2007
    ..Positive results from this trial would add further support for the safety and efficacy of selegiline for the treatment of nicotine dependence. ..