Research Topics
| Margaret PisaniSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort studyMichael T Vest
Section of Pulmonary and Critical Care Medicine, Department of Medicine, Yale University School of Medicine, 333 Cedar Street, PO Box 208057, New Haven, CT 06520 8057 USA
Health Qual Life Outcomes 9:9. 2011..We sought to determine the cross-sectional associations between disability in ADLs and QOL as measured by version one of the Short Form 12-item Health Survey (SF-12) at both one month and one year post-ICU discharge...
Delirium assessment in the intensive care unit: patient population mattersMargaret A Pisani
Department of Internal Medicine, Pulmonary and Critical Care Section, and Program on Aging, Yale University School of Medicine, 333 Cedar Street, PO Box 208057, New Haven, CT 06520 8057, USA
Crit Care 12:131. 2008..Subsequently there has grown a body of literature regarding delirium assessment in critical illness. The present commentary briefly discusses delirium screening in an intensive care unit environment...
Considerations in caring for the critically ill older patientMargaret A Pisani
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Intensive Care Med 24:83-95. 2009..This article will review important physiologic changes of aging, as well as sepsis and delirium and outcomes of older ICU patients...
Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older populationMargaret A Pisani
Department of Internal Medicine, Pulmonary and Critical Care Section, and the Program on Aging, Yale University School of Medicine, USA
Crit Care Med 37:177-83. 2009..The objective of this study was to examine the impact of benzodiazepine or opioid use on the duration of ICU delirium in an older medical population...
Factors associated with persistent delirium after intensive care unit admission in an older medical patient populationMargaret A Pisani
Department of Internal Medicine, Pulmonary and Critical Care Section, and the Program on Aging, Yale University School of Medicine, New Haven, CT 06520 8057, USA
J Crit Care 25:540.e1-7. 2010..This study was designed to identify factors associated with persistent delirium in an older medical intensive care unit (ICU) population...
Characteristics associated with delirium in older patients in a medical intensive care unitMargaret A Pisani
Pulmonary and Critical Care Section, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8057, USA
Arch Intern Med 167:1629-34. 2007..Delirium is a highly prevalent disorder among older patients in the intensive care unit...
A research algorithm to improve detection of delirium in the intensive care unitMargaret A Pisani
Department of Internal Medicine, Pulmonary and Critical Care Section, and the Program on Aging, Yale University School of Medicine, New Haven, CT 06520 8057, USA
Crit Care 10:R121. 2006..The purpose of this study was to develop a research algorithm to enhance detection of delirium in critically ill ICU patients using chart review to complement a validated clinical delirium instrument...
Short-term outcomes in older intensive care unit patients with dementiaMargaret A Pisani
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8057, USA
Crit Care Med 33:1371-6. 2005..To determine the impact of dementia on the outcomes of intensive care unit (ICU) care and use of ICU interventions among older patients...
Cognitive impairment in the intensive care unitMargaret A Pisani
Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8057, USA
Clin Chest Med 24:727-37. 2003..Moreover, studies that examine the impact of delirium prevention in the ICU on rates of delirium, duration and persistence of delirium, and long-term cognitive and functional outcomes post-ICU stay are greatly needed...
Underrecognition of preexisting cognitive impairment by physicians in older ICU patientsMargaret A Pisani
Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, PO Box 208057, New Haven, CT 06520 8057, USA
Chest 124:2267-74. 2003..Little is known, however, about physician recognition of preexisting cognitive impairment in the ICU and which patient factors may play a role in physician recognition...
Screening for preexisting cognitive impairment in older intensive care unit patients: use of proxy assessmentMargaret A Pisani
Department of Internal Medicine, Yale University School ofMedicine, New Haven, Connecticut 06520, USA
J Am Geriatr Soc 51:689-93. 2003..To determine the prevalence of preexisting cognitive impairment (CI) in patients admitted to the medical intensive care unit (ICU) and compare two different proxy measures of preexisting CI in ICU patients...
Days of delirium are associated with 1-year mortality in an older intensive care unit populationMargaret A Pisani
Department of Internal Medicine, Pulmonary and Critical Care Section, and the Program on Aging, Yale University School of Medicine, 333 Cedar Street, P O Box 208057, New Haven, CT 06520 8057, USA
Am J Respir Crit Care Med 180:1092-7. 2009..Delirium is a frequent occurrence in older intensive care unit (ICU) patients, but the importance of the duration of delirium in contributing to adverse long-term outcomes is unclear...
The changing epidemiology of HIV-infected patients in the intensive care unitKathleen M Akgün
Department of Internal Medicine, Pulmonary and Critical Care Section, Yale University School of Medicine, New Haven, CT, USA
J Intensive Care Med 26:151-64. 2011..Future studies are needed to address the role of age, associated comorbidities and impact of HAART on outcomes of HIV-infected patients admitted to the ICU...
Critical illness in HIV-infected patients in the era of combination antiretroviral therapyKathleen M Akgün
VA Connecticut Healthcare System, Department of Internal Medicine, West Haven, Connecticut, USA
Proc Am Thorac Soc 8:301-7. 2011..In addition, we consider issues related to administration of ART in the ICU and identify important areas of future research...
Epidemiology and management of common pulmonary diseases in older personsKathleen M Akgün
Pulmonary and Critical Care Section, Department of Internal Medicine, VA Connecticut Healthcare System, West Haven, USA
J Gerontol A Biol Sci Med Sci 67:276-91. 2012..Finally, we will address the relationship between comorbidities, pulmonary symptoms, and quality of life in older patients with pulmonary diseases...
The use of missingness screens in clinical epidemiologic research has implications for regression modelingPeter H Van Ness
Program on Aging, Department of Internal Medicine, Yale University, School of Medicine, 300 George Street Suite 775, New Haven, CT 06511, USA
J Clin Epidemiol 60:1239-45. 2007..We illustrate methods for understanding whether missing values are ignorable and describe implications of their use in regression modeling...
Mechanical ventilation and acute respiratory distress syndrome in older patientsJonathan M Siner
Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, P O Box 208057, TAC S441C, New Haven, CT 06520 8057, USA
Clin Chest Med 28:783-91, vii. 2007..We conclude with what is known about age and its impact on mortality and functional outcomes after mechanical ventilation...
Detection of delirium in the intensive care unit: comparison of confusion assessment method for the intensive care unit with confusion assessment method ratingsLynn McNicoll
Department of Internal Medicine, School of Medicine, Brown University, Providence, Rhode Island, USA
J Am Geriatr Soc 53:495-500. 2005..To compare the Confusion Assessment Method (CAM) and CAM for the Intensive Care Unit (CAM-ICU) methods for detecting delirium in alert, nonintubated older ICU patients...
Delirium in the intensive care unit: occurrence and clinical course in older patientsLynn McNicoll
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Am Geriatr Soc 51:591-8. 2003..To describe the occurrence of delirium in a cohort of older medical intensive care unit (ICU) patients and its short-term duration in the hospital and to determine the association between preexisting dementia and the occurrence of delirium...
Does gender impact intensity of care provided to older medical intensive care unit patients?Kathleen M Akgün
Pulmonary and Critical Care Section, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street P O Box 208057, New Haven, CT 06520 8057, USA
Crit Care Res Pract 2010:404608. 2010..Conclusions. In contrast with other reports from the cardiac critical care literature, as measured by the TISS-28, gender-based care delivered to older MICU patients in this cohort was equivalent...
Research Grants
- Impact of Psychoactive Drugs on Delirium in ICU PatientsMargaret Pisani; Fiscal Year: 2007..Ultimately, we hope this work will lead to the development of specific interventions in ICU drug therapy vital to the care of more than four million critically ill patients in the United States. ..
- Feasibility of Measuring Sleep in a Critical Care EnvironmentMargaret A Pisani; Fiscal Year: 2010....
