M A Perazella

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Hemodynamics in patients with intradialytic hypotension treated with cool dialysate or midodrine
    Heidi Hoeben
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 39:102-7. 2002
  2. doi request reprint AKI in a hospitalized patient with cellulitis
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Clin J Am Soc Nephrol 8:658-64. 2013
  3. doi request reprint Proton pump inhibitors and hypomagnesemia: a rare but serious complication
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Kidney Int 83:553-6. 2013
  4. doi request reprint Onco-nephrology: renal toxicities of chemotherapeutic agents
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University, 330 Cedar Street, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 7:1713-21. 2012
  5. doi request reprint Drug use and nephrotoxicity in the intensive care unit
    Mark A Perazella
    Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Kidney Int 81:1172-8. 2012
  6. pmc Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review
    Dinna N Cruz
    Department of Nephrology, Ospedale San Bortolo, Viale Rodolfi 37, 36100 Vicenza, Italy
    Crit Care 11:R47. 2007
  7. ncbi request reprint Nephrogenic systemic fibrosis and gadolinium-based contrast: what's a nephrologist to do?
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 21:121-2. 2008
  8. ncbi request reprint Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity
    Mark A Perazella
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Med Sci 325:349-62. 2003
  9. ncbi request reprint Efficacy and safety of midodrine in the treatment of dialysis-associated hypotension
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, LMP 2071, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Expert Opin Drug Saf 2:37-47. 2003
  10. doi request reprint Tenofovir-induced kidney disease: an acquired renal tubular mitochondriopathy
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06410, USA
    Kidney Int 78:1060-3. 2010

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Hemodynamics in patients with intradialytic hypotension treated with cool dialysate or midodrine
    Heidi Hoeben
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 39:102-7. 2002
    ..Cool dialysate and midodrine appear to improve intradialytic hemodynamics in patients with dialysis-associated hypotension, mainly through the preservation of CBV and CO, rather than significantly elevating PVR...
  2. doi request reprint AKI in a hospitalized patient with cellulitis
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Clin J Am Soc Nephrol 8:658-64. 2013
    ..The roles of an accurate history, physical examination, laboratory data, and kidney biopsy are highlighted in establishing the correct diagnosis in such patients...
  3. doi request reprint Proton pump inhibitors and hypomagnesemia: a rare but serious complication
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Kidney Int 83:553-6. 2013
    ..The effect was seen only in those concomitantly receiving diuretics...
  4. doi request reprint Onco-nephrology: renal toxicities of chemotherapeutic agents
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University, 330 Cedar Street, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 7:1713-21. 2012
    ..Onco-Nephrology is a new area that is rapidly expanding and requires a close working relationship between oncologists and nephrologists...
  5. doi request reprint Drug use and nephrotoxicity in the intensive care unit
    Mark A Perazella
    Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Kidney Int 81:1172-8. 2012
    ....
  6. pmc Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review
    Dinna N Cruz
    Department of Nephrology, Ospedale San Bortolo, Viale Rodolfi 37, 36100 Vicenza, Italy
    Crit Care 11:R47. 2007
    ..We performed a systematic review to describe the effect in septic patients of direct hemoperfusion with PMX-F on outcomes of blood pressure, use of vasoactive drugs, oxygenation, and mortality reported in published studies...
  7. ncbi request reprint Nephrogenic systemic fibrosis and gadolinium-based contrast: what's a nephrologist to do?
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 21:121-2. 2008
  8. ncbi request reprint Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity
    Mark A Perazella
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Med Sci 325:349-62. 2003
    ..Agents recently described to induce an "osmotic nephrosis" include intravenous immunoglobulin and the plasma expander hydroxyethyl starch...
  9. ncbi request reprint Efficacy and safety of midodrine in the treatment of dialysis-associated hypotension
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, LMP 2071, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Expert Opin Drug Saf 2:37-47. 2003
    ..This medication has been demonstrated to be effective and safe in the acute and chronic treatment of haemodialysis-associated hypotension in end stage renal disease patients...
  10. doi request reprint Tenofovir-induced kidney disease: an acquired renal tubular mitochondriopathy
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06410, USA
    Kidney Int 78:1060-3. 2010
    ..Herlitz et al. confirm the nephrotoxicity of tenofovir in humans. They describe its clinical consequences, histopathologic findings, and its mitochondrial toxicity in HIV+ patients...
  11. pmc Urine microscopy is associated with severity and worsening of acute kidney injury in hospitalized patients
    Mark A Perazella
    Section of Nephrology, Yale University, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 5:402-8. 2010
    ..Although urine microscopy is useful to differentiate AKI, its role in predicting adverse clinical outcomes has not been well described...
  12. ncbi request reprint Increased mortality in chronic kidney disease: a call to action
    Mark A Perazella
    Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Am J Med Sci 331:150-3. 2006
    ..Therefore, therapies targeting both progression of chronic kidney disease and comorbidities such as cardiovascular disease are required to reduce mortality among these patients...
  13. ncbi request reprint Radiocontrast-induced nephropathy: an update
    M A Perazella
    Acute Dialysis Services, Section of Nephrology, Department of Medicine, Yale University School of Medicine, FMP 107, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Minerva Urol Nefrol 61:215-33. 2009
    ..Several therapies have no role in the prevention of RCIN and should be avoided. This review will provide an up to date examination of the current status of these issues as they relate to RCIN...
  14. doi request reprint Renal vulnerability to drug toxicity
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University, New Haven, Connecticut 06520 8029, USA
    Clin J Am Soc Nephrol 4:1275-83. 2009
    ..Recognizing risk factors that increase renal vulnerability to drug-induced kidney disease is the first step in reducing the renal complications of drugs and toxins...
  15. doi request reprint Current status of gadolinium toxicity in patients with kidney disease
    Mark A Perazella
    Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Clin J Am Soc Nephrol 4:461-9. 2009
    ..This article reviews the current status of GBC agents as nephrotoxins and causes of NSF and provides opinions on how to use these agents in patients with underlying kidney disease...
  16. doi request reprint Tissue deposition of gadolinium and development of NSF: a convergence of factors
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 21:150-4. 2008
    ..Direct gadolinium activation of transglutaminases on these tissue fibroblast-like cells may also promote fibrosis...
  17. ncbi request reprint Gadolinium-contrast toxicity in patients with kidney disease: nephrotoxicity and nephrogenic systemic fibrosis
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Curr Drug Saf 3:67-75. 2008
    ..Peritoneal dialysis clearance of gadolinium is poor, but aggressive peritoneal dialysis prescriptions have not been studied for gadolinium removal...
  18. doi request reprint Nephrogenic systemic fibrosis: recommendations for gadolinium-based contrast use in patients with kidney disease
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 21:171-3. 2008
    ..These clinical practice guidelines should be individualized and considered in consultation with the ordering physician, radiologist, and nephrologist...
  19. ncbi request reprint Drug-induced nephropathy: an update
    Mark A Perazella
    Yale University School of Medicine, FMP 107, 300 Cedar Street, New Haven, CT 06520 8029, USA
    Expert Opin Drug Saf 4:689-706. 2005
    ..Finally, postrenal azotemia from structural or functional obstruction of the urinary tract also complicates therapy with a number of medications...
  20. ncbi request reprint Pharmacology
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 46:1129-39. 2005
  21. pmc Diagnostic value of urine microscopy for differential diagnosis of acute kidney injury in hospitalized patients
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 3:1615-9. 2008
    ..Urine microscopy is the oldest and one of the most commonly used tests for differential diagnosis of acute kidney injury (AKI), but its performance has not been adequately studied in the setting of AKI...
  22. doi request reprint Imaging patients with kidney disease: how do we approach contrast-related toxicity?
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, VA Connecticut Health Care System, New Haven, 06520 8029, USA
    Am J Med Sci 341:215-21. 2011
    ..This will allow one to maximize the diagnostic efficiency while also limiting the adverse effects...
  23. ncbi request reprint Acute renal failure in HIV-infected patients: a brief review of common causes
    M A Perazella
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Am J Med Sci 319:385-91. 2000
    ..Finally, obstruction of the urinary system will rarely cause postrenal azotemia in patients infected with HIV...
  24. ncbi request reprint Trimethoprim-induced hyperkalaemia: clinical data, mechanism, prevention and management
    M A Perazella
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Drug Saf 22:227-36. 2000
    ....
  25. ncbi request reprint Are selective COX-2 inhibitors nephrotoxic?
    M A Perazella
    Department of Internal Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Kidney Dis 35:937-40. 2000
    ..We present two cases of acute renal failure complicating the course of therapy with celecoxib in patients with chronic renal insufficiency...
  26. ncbi request reprint Pharmacologic options available to treat symptomatic intradialytic hypotension
    M A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 38:S26-36. 2001
    ..A few therapies appear to be efficacious and well tolerated-carnitine, sertraline, and midodrine. This article reviews the various pharmacologic therapies used for IDH and makes recommendations for treatment of this difficult problem...
  27. doi request reprint Traditional urinary biomarkers in the assessment of hospital-acquired AKI
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, BB 114, 330 Cedar Street, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 7:167-74. 2012
    ....
  28. ncbi request reprint COX-2 selective inhibitors: analysis of the renal effects
    Mark A Perazella
    Acute Dialysis Services, Section of Nephrology, Department of Medicine, Yale University School of Medicine, LMP 2071, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Expert Opin Drug Saf 1:53-64. 2002
    ..Available clinical data on the renal effects of COX-2 selective inhibitors in humans also demonstrate nephrotoxic potential...
  29. doi request reprint Nephrotoxicity from chemotherapeutic agents: clinical manifestations, pathobiology, and prevention/therapy
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    Semin Nephrol 30:570-81. 2010
    ..This article reviews some of the classic nephrotoxic chemotherapeutic agents and focuses on examples of the clinical and histopathologic kidney lesions they cause as well as measures that may prevent or treat drug-induced nephrotoxicity...
  30. ncbi request reprint Experience with outpatient computed tomographic-guided renal biopsy
    A Margaryan
    Section of Nephrology, Yale School of Medicine, New Haven, CT, USA
    Clin Nephrol 74:440-5. 2010
    ..Transfusion was required in 1 patient while 6 patients had detectable bleeding and were hospitalized for observation. Outpatient CT-guided kidney biopsy provides adequate tissue and appears to be safe with very low complication rates...
  31. ncbi request reprint NSAIDs and the kidney revisited: are selective cyclooxygenase-2 inhibitors safe?
    J Eras
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Am J Med Sci 321:181-90. 2001
    ..We also touch on the COX-1/COX-2 selectivity of NSAIDs, the localization of COX enzymes in kidneys, and clinical studies examining the renal effects of selective COX-2 inhibitors...
  32. ncbi request reprint COX-2 inhibitors and the kidney
    M A Perazella
    Yale University School of Medicine, New Haven, Conn, USA
    Hosp Pract (Minneap) 36:43-6, 55-6. 2001
    ..COX-2 inhibitors may thus have much the same renal risks that a standard NSAID does. Several clinical trials have already focused on the new drugs' renal effects...
  33. ncbi request reprint Crystal-induced acute renal failure
    M A Perazella
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Am J Med 106:459-65. 1999
    ..Management of established renal insufficiency includes volume repletion, dialytic support if necessary, adjustment of drug doses, and avoidance of further exposure to nephrotoxins...
  34. ncbi request reprint Proton pump inhibitors and the kidney: critical review
    U C Brewster
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Clin Nephrol 68:65-72. 2007
    ..This paper will critically review the effect of PPIs on the kidney...
  35. ncbi request reprint Treatment of Severe Intradialytic Hypotension With the Addition of High Dialysate Calcium Concentration to Midodrine and/or Cool Dialysate
    R Alappan
    Section of Nephrology, Yale University School of Medicine, New Haven, CT, USA
    Am J Kidney Dis 37:294-9. 2001
    ..However, this therapy did not reduce symptoms or interventions required for IDH. In addition, hypercalcemia complicated this therapy in 22% of the patients...
  36. doi request reprint Advanced kidney disease, gadolinium and nephrogenic systemic fibrosis: the perfect storm
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Curr Opin Nephrol Hypertens 18:519-25. 2009
    ..However, many patients with kidney disease are exposed to GBC agents, yet they do not develop this devastating disorder...
  37. ncbi request reprint Acute hyperkalemia associated with intravenous epsilon-aminocaproic acid therapy
    M A Perazella
    Department of Medicine, Yale University, New Haven, CT, USA
    Am J Kidney Dis 33:782-5. 1999
    ..Hence, it appears that intravenous epsilon-aminocaproic acid can also cause hyperkalemia in humans...
  38. ncbi request reprint Imaging patients with kidney disease in the era of NSF: can it be done safely?
    V Manjunath
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Clin Nephrol 75:279-85. 2011
    ....
  39. ncbi request reprint The cardiovascular implications of hypokalemia
    Steven G Coca
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 45:233-47. 2005
    ..We review the available data and draw conclusions about the relative benefits of modulating potassium balance versus nonrenal effects of aldosterone blockade in patients with cardiovascular disease...
  40. ncbi request reprint Transition of patients from chronic kidney disease to end-stage renal disease: better practices for better outcomes
    Chester A Amedia
    Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Boardman, Ohio 44512, USA
    Dis Manag 9:311-5. 2006
  41. ncbi request reprint Drug-induced crystal nephropathy: an update
    Sri G Yarlagadda
    Yale University School of Medicine, Section of Nephrology Department of Medicine, LMP 2071, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Expert Opin Drug Saf 7:147-58. 2008
    ....
  42. pmc Serum vasopressin response in patients with intradialytic hypotension: a pilot study
    Mira Rho
    Yale University School of Medicine, New Haven, CT 06520, USA
    Clin J Am Soc Nephrol 3:729-35. 2008
    ..Arginine vasopressin (AVP), an endogenous hormone with vasopressor properties, may be inadequately secreted during episodes of intradialytic hypotension (IDH)...
  43. ncbi request reprint Indinavir nephropathy revisited: a pattern of insidious renal failure with identifiable risk factors
    R F Reilly
    Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Kidney Dis 38:E23. 2001
    ..We review the literature of renal syndromes associated with indinavir focusing on chronic progressive tubulointerstitial injury and speculate on risk factors and potential mechanisms of indinavir-induced renal injury...
  44. ncbi request reprint Reliability of a noninvasive device to measure systemic hemodynamics in hemodialysis patients
    Shaheen Motiwala
    Section of Nephrology, Yale University, New Haven, Connecticut, USA
    Blood Press Monit 11:33-6. 2006
    ..To evaluate the reliability of a noninvasive hemodynamic monitor in hemodialysis patients...
  45. ncbi request reprint Nonhematologic complications of erythropoietin therapy
    Xiaolei Zhu
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 19:279-84. 2006
    ..Finally, other less common adverse effects, although rare in most patients, should be recognized as such by physicians who prescribe rHuEPO...
  46. ncbi request reprint Renal disease in patients with HIV infection: epidemiology, pathogenesis and management
    Derek M Fine
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Drugs 68:963-80. 2008
    ..Only with greater awareness of kidney-disease manifestations and their implications in this particularly vulnerable population will we be able to achieve success in confronting this growing problem...
  47. ncbi request reprint Rapid communication: acute renal failure associated with tenofovir: evidence of drug-induced nephrotoxicity
    Steven Coca
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, LMP 2071, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Am J Med Sci 324:342-4. 2002
    ..We present a case in which acute renal failure developed after therapy with tenofovir DF in a patient with HIV and stable chronic kidney disease...
  48. ncbi request reprint Addition of sertraline to other therapies to reduce dialysis-associated hypotension
    Ursula C Brewster
    Yale University School of Medicine, Section of Nephrology, New Haven, CT 06520, USA
    Nephrology (Carlton) 8:296-301. 2003
    ..In conclusion, it appears that sertraline has no additive effect on intradialytic haemodynamics to improve blood pressure in patients with DAH who are under therapy (with sodium modelling, cool dialysate and midodrine)...
  49. pmc Hyperkalemia in the elderly: drugs exacerbate impaired potassium homeostasis
    M A Perazella
    Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520 8029, USA
    J Gen Intern Med 12:646-56. 1997
    ....
  50. ncbi request reprint Recognition, treatment, and prevention of propylene glycol toxicity
    Tausif Zar
    Sections of Nephrology, Department of Medicine, University of Connecticut, Farmington, Connecticut 06030, USA
    Semin Dial 20:217-9. 2007
    ..Treatment of toxicity includes hemodialysis to effectively remove propylene glycol. Prevention is best achieved by limiting the dose of propylene glycol infused...
  51. ncbi request reprint Gadolinium-induced nephrogenic systemic fibrosis in patients with kidney disease
    Mark A Perazella
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Conn, USA
    Am J Med 120:561-2. 2007
  52. doi request reprint Erythropoiesis stimulatory agent- resistant anemia in dialysis patients: review of causes and management
    Mehmet Kanbay
    Department of Medicine, Section of Nephrology, Fatih University School of Medicine, Ankara, Turkey
    Blood Purif 29:1-12. 2010
    ..The aim of the present review is to provide an update of the recent literature on causes and possible management of ESA-resistant anemia in CKD patients...
  53. ncbi request reprint Nephrotoxicity associated with antiretroviral therapy in HIV-infected patients
    Mira Rho
    Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Curr Drug Saf 2:147-54. 2007
    ..Recognition of drug-related nephrotoxicity will promote earlier resolution of acute kidney injury and reduce the development of chronic kidney disease...
  54. ncbi request reprint Cachexia in a 53-year-old end-stage renal disease patient on hemodialysis
    Chirag Vaidya
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Semin Dial 20:475-6. 2007
  55. ncbi request reprint The renin-angiotensin-aldosterone system: cardiorenal effects and implications for renal and cardiovascular disease states
    Ursula C Brewster
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Sci 326:15-24. 2003
    ....
  56. ncbi request reprint Renin-angiotensin-aldosterone system: fundamental aspects and clinical implications in renal and cardiovascular disorders
    Mark A Perazella
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520 8017, USA
    J Nucl Cardiol 10:184-96. 2003
    ....
  57. doi request reprint Nephrogenic systemic fibrosis: what the hospitalist needs to know
    Derek M Fine
    Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Hosp Med 5:46-50. 2010
    ..Unfortunately there is a lack of a universally effective therapy. Resolution of acute kidney injury (AKI) appears to attenuate disease in most cases, while kidney transplantation has been associated with variable success...
  58. ncbi request reprint Cardiac troponins: utility in renal insufficiency and end-stage renal disease
    Suzanne Watnick
    Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 15:66-70. 2002
    ....
  59. ncbi request reprint Posttransplant erythrocytosis: case report and review of newer treatment modalities
    M A Perazella
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510
    J Am Soc Nephrol 3:1653-9. 1993
    ..Theophylline, which reduces adenosine-mediated erythropoietin synthesis, is effective but may be associated with side effects.(ABSTRACT TRUNCATED AT 250 WORDS)..
  60. pmc Acute renal failure after cardiac transplantation: a case report and review of the literature
    D N Cruz
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8029, USA
    Yale J Biol Med 69:461-8. 1996
    ..A case illustrating the typical clinical presentation of ARF after heart transplant will be presented and the clinical features will be reviewed...
  61. ncbi request reprint Acute kidney injury following proton pump inhibitor therapy
    U C Brewster
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520 9029, USA
    Kidney Int 71:589-93. 2007
  62. ncbi request reprint The role of aldosterone blockers in the management of chronic heart failure
    Steven G Coca
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Sci 330:176-83. 2005
    ..Herein, the pathophysiology of CHF, the beneficial role of aldosterone antagonists in this disease process, and potential adverse consequences of these agents are reviewed...
  63. ncbi request reprint Adverse cardiorenal effects of aldosterone: is aldosterone antagonism beneficial?
    Steven G Coca
    Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Expert Rev Cardiovasc Ther 3:497-512. 2005
    ..In particular, the authors review their effects on reductions in cardiovascular events and progression of chronic kidney disease, as well as the safety and tolerability of these agents...
  64. ncbi request reprint Retroperitoneal bleed from acquired renal cysts
    Jeffrey Stein
    Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 19:256. 2006
  65. doi request reprint Drug-induced acute interstitial nephritis
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, FMP 107, 330 Cedar Street, New Haven, CT 06520 8029, USA
    Nat Rev Nephrol 6:461-70. 2010
    ..In general, the prognosis for drug-induced AIN is good, and at least partial recovery of kidney function is normally observed. Early recognition is crucial because patients can ultimately develop chronic kidney disease...
  66. ncbi request reprint Effect of intravenous iron on haemodialysis catheter microbial colonization and blood-borne infection
    Ursula C Brewster
    Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Nephrology (Carlton) 10:124-8. 2005
    ..v. iron increases infection risk. This pilot study examines whether i.v. iron gluconate acutely increases tunnelled haemodialysis catheter colonization, microbial growth, or blood-borne infection...
  67. ncbi request reprint A review of chronic lead intoxication: an unrecognized cause of chronic kidney disease
    Ursula C Brewster
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Sci 327:341-7. 2004
    ..In particular, treatment with calcium EDTA chelation may benefit certain patients with chronic kidney disease by slowing the progression to end-stage renal disease...
  68. ncbi request reprint Intradialytic administration of amphotericin B: clinical observations on efficacy and safety
    James E Wood
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Med Sci 327:5-8. 2004
    ..Amphotericin B is used commonly to treat fungal infections. Unfortunately, little information exists regarding the use of intravenous amphotericin B in patients with end-stage renal disease (ESRD)...
  69. ncbi request reprint The renin-angiotensin-aldosterone system and the kidney: effects on kidney disease
    Ursula C Brewster
    Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Am J Med 116:263-72. 2004
    ....
  70. ncbi request reprint Recent onset of focal arteriovenous graft swelling
    Ursula C Brewster
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 19:84. 2006
  71. ncbi request reprint Nephrogenic fibrosing dermopathy: an unusual skin condition associated with kidney disease
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Semin Dial 16:276-80. 2003
    ..In contrast to scleroderma, inflammatory cells are generally absent. Corticosteroid therapy can be tried, but in our patient was of no benefit...
  72. doi request reprint A case of extreme hemodynamic lability and hypocalcemia
    Felix Knauf
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Am J Med Sci 338:241-4. 2009
    ..We discuss the initial management, diagnosis, and definitive therapy of this relatively rare type of pheochromocytoma...
  73. doi request reprint Bisphosphonate nephrotoxicity
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut, USA
    Kidney Int 74:1385-93. 2008
    ..Available data suggest that ibandronate has a safe renal profile without evidence of nephrotoxicity, even in patients with abnormal baseline kidney function...
  74. ncbi request reprint Chronic kidney disease: a new approach to an old problem
    Robert F Reilly
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, USA
    Conn Med 66:579-83. 2002
    ..We herein review and summarize clinical practice guidelines put forward by the National Kidney Foundation Working Group to aid physicians in the diagnosis and management of CKD...
  75. doi request reprint Nephrogenic systemic fibrosis associated with gadoversetamide exposure: treatment with sodium thiosulfate
    Deepak Kadiyala
    St Mary s Hospital, Waterbury, CT, USA
    Am J Kidney Dis 53:133-7. 2009
    ..Two patients received gadoversetamide and the third received gadodiamide. All 3 patients were treated early in their disease course with intravenous sodium thiosulfate and responded with improved skin changes and joint mobility...
  76. doi request reprint Acute tubular necrosis and pre-renal acute kidney injury: utility of urine microscopy in their evaluation- a systematic review
    Mehmet Kanbay
    Section of Nephrology, Department of Medicine, Fatih University School of Medicine, Ankara, Turkey
    Int Urol Nephrol 42:425-33. 2010
    ..More often, tests such as fractional excretion of sodium (FeNa) and fractional excretion of urea (FeUrea) are used to differentiate these two causes of acute kidney injury...
  77. ncbi request reprint Acute interstitial nephritis associated with atazanavir, a new protease inhibitor
    Ursula C Brewster
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 44:e81-4. 2004
    ..Renal biopsy showed acute interstitial nephritis. This is the first report of acute interstitial nephritis from atazanavir...
  78. ncbi request reprint Hip fractures in end-stage renal disease patients: incidence, risk factors, and prevention
    Lisa Leinau
    Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Semin Dial 19:75-9. 2006
    ..Because falls occur frequently in the dialysis population, simple fall prevention may be one important way of protecting dialysis patients from the morbidity and mortality of hip fracture...
  79. ncbi request reprint Percutaneous balloon cryoplasty: a new therapy for rapidly recurrent anastomotic venous stenoses of hemodialysis grafts?
    Brian S Rifkin
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Kidney Dis 45:e27-32. 2005
    ..Cryotherapy with the cryoballoon (cryoplasty) may represent a useful therapy for patients with intractable stenoses at or near the venous anastomosis of arteriovenous grafts...
  80. ncbi request reprint Can dual blockade of the renin-angiotensin system reduce progression of kidney disease beyond monotherapy?
    Ursula C Brewster
    Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, LMP 2071, 333 Cedar Street, New Haven, CT 06520 8029, USA
    Expert Opin Drug Saf 3:9-23. 2004
    ..The efficacy and safety of dual RAS blockade in proteinuric renal diseases will be examined. Finally, recommendations for utilising combined therapy with ACE inhibitors and ARBs will be provided...
  81. ncbi request reprint Calcific uremic arteriolopathy in a transplanted kidney
    Ursula C Brewster
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520 8029, USA
    Am J Med Sci 329:102-3. 2005
    ..However, other organs may be involved. We report a case of a young man who developed renal failure in the transplanted kidney. Renal biopsy demonstrated myointimal calcification in the renal arteries consistent with this diagnosis...
  82. ncbi request reprint Access stenosis and stent fracture
    Ursula C Brewster
    Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    Am J Kidney Dis 47:A45, e35-6. 2006
  83. ncbi request reprint An unexpected finding on chest roentgenogram following hemodialysis catheter placement
    Swathi Singanamala
    Department of Medicine, St Mary s Hospital, Waterbury, Connecticut, USA
    Semin Dial 21:293-4. 2008
  84. ncbi request reprint Calcific uremic arteriolopathy (calciphylaxis)
    Brian S Rifkin
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Conn, USA
    Mayo Clin Proc 81:9. 2006
  85. ncbi request reprint Pamidronate-associated nephrotoxicity in a patient with Langerhans's histiocytosis
    Les Lockridge
    Department of Medicine, Section of Oncology and Section of Nephrology, Yale University, New Haven, CT 06529 8029, USA
    Am J Kidney Dis 40:E2. 2002
    ..We encountered a patient with Langerhans's histiocytosis who developed nephrotic syndrome and renal failure after pamidronate therapy. We describe the clinical and renal biopsy findings in this patient...
  86. ncbi request reprint Pain and swelling at a Tenckhoff catheter tunnel site
    Sri Yarlagadda
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Semin Dial 19:438-9. 2006
  87. doi request reprint Systemic diseases with renal manifestations
    Asha Rajashekar
    Division of Nephrology, Yale School of Medicine, 330 Cedar Street, FMP107, New Haven, CT 06510, USA
    Prim Care 35:297-328, vi-vii. 2008
    ..Dysproteinemias are associated with protean renal manifestations, and renal disease may be the presenting manifestation...
  88. ncbi request reprint How should nephrologists approach gadolinium-based contrast imaging in patients with kidney disease?
    Mark A Perazella
    Clin J Am Soc Nephrol 3:649-51. 2008
  89. ncbi request reprint Nephrogenic systemic fibrosis, kidney disease, and gadolinium: is there a link?
    Mark A Perazella
    Clin J Am Soc Nephrol 2:200-2. 2007
  90. ncbi request reprint Gadolinium use in patients with kidney disease: a cause for concern
    Mark A Perazella
    Semin Dial 20:179-85. 2007
    ..Caution should be exercised when utilizing gadolinium as a contrast agent in patients with advanced CKD or ESRD...
  91. ncbi request reprint Angiotensin-converting enzyme inhibitors and anemia in chronic kidney disease: a complex interaction
    Ali K Abu-Alfa
    Am J Kidney Dis 39:896-7. 2002
  92. doi request reprint Kidney biopsy in HIV: beyond HIV-associated nephropathy
    Derek M Fine
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Kidney Dis 51:504-14. 2008
  93. ncbi request reprint Extracorporeal blood purification therapies for prevention of radiocontrast-induced nephropathy: a systematic review
    Dinna N Cruz
    Department of Nephrology, San Bortolo Hospital, Vicenza, Italy
    Am J Kidney Dis 48:361-71. 2006
    ..We conducted a systematic review of published trials to determine whether periprocedural extracorporeal blood purification prevents RCIN...
  94. ncbi request reprint Acute tubulointerstitial nephritis associated with celecoxib
    Ursula C Brewster
    Nephrol Dial Transplant 19:1017-8. 2004
  95. ncbi request reprint An odd case of hypertension
    John E Aruny
    Section of Interventional Radiology, Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, Conn 06520 8029, USA
    Am J Med 119:748-50. 2006
  96. ncbi request reprint Prevention of contrast-induced nephropathy in high-risk patients with hemofiltration
    Steven G Coca
    Am J Med 120:e9; author reply e11. 2007
  97. ncbi request reprint Drug-induced renal failure: a focus on tubulointerstitial disease
    Glen S Markowitz
    Department of Pathology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Clin Chim Acta 351:31-47. 2005
    ..This review focuses on the multitude of patterns of drug-induced renal failure due to tubulointerstitial disease...
  98. ncbi request reprint North East Italian Prospective Hospital Renal Outcome Survey on Acute Kidney Injury (NEiPHROS-AKI): targeting the problem with the RIFLE Criteria
    Dinna N Cruz
    Department of Nephrology and Intensive Care, San Bortolo Hospital, Vicenza, Italy
    Clin J Am Soc Nephrol 2:418-25. 2007
    ..3% of ICU patients requiring renal replacement therapy. Sepsis was a significant contributing factor. Overall mortality was between 30 and 42%, and was highest among those in RIFLE class F...
  99. ncbi request reprint Tenofovir-associated nephrotoxicity: Fanconi syndrome and renal failure
    Brian S Rifkin
    Am J Med 117:282-4. 2004
  100. ncbi request reprint Intravenous iron and the risk of infection in end-stage renal disease patients
    Ursula C Brewster
    Section of Nephrology, Yale University School of Medicine, New Haven, 06520 8029, USA
    Semin Dial 17:57-60. 2004
    ..Practicing nephrologists should be aware of this issue, but should not hesitate to use IV iron in iron-deficient patients while avoiding the development of iron overload and administration of iron to patients who have active infection...
  101. ncbi request reprint Acute oxalate nephropathy associated with orlistat, a gastrointestinal lipase inhibitor
    Ashutosh Singh
    Department of Pathology, University of Tennessee Health Sciences Center, Memphis, TN, USA
    Am J Kidney Dis 49:153-7. 2007
    ..A steady improvement in renal function subsequently was observed. Results of a repeated 24-hour urine oxalate collection performed 3 weeks later when kidney function had improved were within normal limits...