Chirag Parikh

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi request reprint Urine stability studies for novel biomarkers of acute kidney injury
    Chirag R Parikh
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT Electronic address
    Am J Kidney Dis 63:567-72. 2014
  2. pmc An eUtils toolset and its use for creating a pipeline to link genomics and proteomics analyses to domain-specific biomedical literature
    Prakash M Nadkarni
    Department of Medicine, Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT, USA
    J Clin Bioinforma 2:9. 2012
  3. pmc Performance of kidney injury molecule-1 and liver fatty acid-binding protein and combined biomarkers of AKI after cardiac surgery
    Chirag R Parikh
    Program of Applied Translational Research, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Clin J Am Soc Nephrol 8:1079-88. 2013
  4. pmc Deceased-donor kidney perfusate and urine biomarkers for kidney allograft outcomes: a systematic review
    Ronik S Bhangoo
    Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT, USA
    Nephrol Dial Transplant 27:3305-14. 2012
  5. pmc Evaluation of urine biomarkers of kidney injury in polycystic kidney disease
    Chirag R Parikh
    Department of Medicine Nephrology, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Kidney Int 81:784-90. 2012
  6. pmc Leveraging a clinical research information system to assist biospecimen data and workflow management: a hybrid approach
    Prakash M Nadkarni
    Yale University School of Medicine, New Haven, CT, USA
    J Clin Bioinforma 1:22. 2011
  7. pmc Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study
    Michael Zappitelli
    Texas Children s Hospital, Fannin Street, Houston, Texas 77030, USA
    Crit Care 11:R84. 2007
  8. pmc The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
  9. doi request reprint Impact of acute kidney injury on long-term mortality after nonmyeloablative hematopoietic cell transplantation
    Chirag R Parikh
    Section of Nephrology and Clinical Epidemiology Research Center, Yale New Haven Hospital and VAMC, New Haven, Connecticut, USA
    Biol Blood Marrow Transplant 14:309-15. 2008
  10. ncbi request reprint Biomarkers of acute kidney injury: early diagnosis, pathogenesis, and recovery
    Chirag R Parikh
    Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Investig Med 55:333-40. 2007

Detail Information

Publications71

  1. doi request reprint Urine stability studies for novel biomarkers of acute kidney injury
    Chirag R Parikh
    Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT Electronic address
    Am J Kidney Dis 63:567-72. 2014
    ..We examined how variations in short-term storage and processing might affect the measurement of urine biomarkers...
  2. pmc An eUtils toolset and its use for creating a pipeline to link genomics and proteomics analyses to domain-specific biomedical literature
    Prakash M Nadkarni
    Department of Medicine, Program of Applied Translational Research, Yale University School of Medicine, New Haven, CT, USA
    J Clin Bioinforma 2:9. 2012
    ..abstract:..
  3. pmc Performance of kidney injury molecule-1 and liver fatty acid-binding protein and combined biomarkers of AKI after cardiac surgery
    Chirag R Parikh
    Program of Applied Translational Research, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Clin J Am Soc Nephrol 8:1079-88. 2013
    ..AKI is common and novel biomarkers may help provide earlier diagnosis and prognosis of AKI in the postoperative period...
  4. pmc Deceased-donor kidney perfusate and urine biomarkers for kidney allograft outcomes: a systematic review
    Ronik S Bhangoo
    Section of Nephrology, Department of Medicine, Yale School of Medicine, New Haven, CT, USA
    Nephrol Dial Transplant 27:3305-14. 2012
    ....
  5. pmc Evaluation of urine biomarkers of kidney injury in polycystic kidney disease
    Chirag R Parikh
    Department of Medicine Nephrology, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Kidney Int 81:784-90. 2012
    ..This may be due, in part, to the lack of communication between individual cysts and the urinary collecting system in this disorder...
  6. pmc Leveraging a clinical research information system to assist biospecimen data and workflow management: a hybrid approach
    Prakash M Nadkarni
    Yale University School of Medicine, New Haven, CT, USA
    J Clin Bioinforma 1:22. 2011
    ..abstract:..
  7. pmc Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study
    Michael Zappitelli
    Texas Children s Hospital, Fannin Street, Houston, Texas 77030, USA
    Crit Care 11:R84. 2007
    ..It is unknown whether uNGAL predicts AKI in the general critical care setting. We assessed the ability of uNGAL to predict AKI development and severity in critically ill children...
  8. pmc The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
    ..Previous studies on hospital-acquired AKI have important methodological limitations, especially their retrospective study designs and limited ability to control for potential confounding factors...
  9. doi request reprint Impact of acute kidney injury on long-term mortality after nonmyeloablative hematopoietic cell transplantation
    Chirag R Parikh
    Section of Nephrology and Clinical Epidemiology Research Center, Yale New Haven Hospital and VAMC, New Haven, Connecticut, USA
    Biol Blood Marrow Transplant 14:309-15. 2008
    ..07). AKI is an independent predictor of overall mortality after nonmyeloablative HCT. This finding reiterates the importance of identifying preventative strategies in nonmyeloablative HCT for attenuating incidence and severity of AKI...
  10. ncbi request reprint Biomarkers of acute kidney injury: early diagnosis, pathogenesis, and recovery
    Chirag R Parikh
    Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Investig Med 55:333-40. 2007
    ..The final talk discussed the role of circulating stem cells in renal tubule regeneration after ischemic injury and if they have potential for biomarkers of recovery or therapeutic intervention...
  11. ncbi request reprint Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery
    C R Parikh
    Section of Nephrology, Yale University, New Haven, Connecticut 06516, USA
    Kidney Int 70:199-203. 2006
    ..The combination of these two biomarkers may allow for the reliable early diagnosis and prognosis of AKI at all times after CPB, much before the rise in serum creatinine...
  12. ncbi request reprint Study designs in patient-oriented research
    Chirag R Parikh
    Department of Medicine, Clinical Epidemiology Research Center, Yale University School of Medicine, New Haven, CT, USA
    Am J Kidney Dis 47:356-64. 2006
  13. ncbi request reprint Acute renal failure in hematopoietic cell transplantation
    C R Parikh
    Section of Nephrology, Yale University and VAMC, West Haven, Connecticut, USA
    Kidney Int 69:430-5. 2006
    ..The reduction of acute renal failure will have several advantages, including reducing mortality and the burden of chronic kidney disease following transplantation...
  14. ncbi request reprint Acute renal failure independently predicts mortality after myeloablative allogeneic hematopoietic cell transplant
    Chirag R Parikh
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06473, USA
    Kidney Int 67:1999-2005. 2005
    ..Patients undergoing myeloablative allogeneic hematopoietic cell transplantation (HCT) have a high incidence of acute renal failure (ARF). However, it is unclear if ARF is independently associated with mortality after this procedure...
  15. pmc Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery
    Chirag R Parikh
    Section of Nephrology, Yale University and Veterans Administration Medical Center, 950 Campbell Avenue, Mail Code 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 22:1748-57. 2011
    ..In conclusion, urine IL-18, urine NGAL, and plasma NGAL associate with subsequent AKI and poor outcomes among adults undergoing cardiac surgery...
  16. pmc Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery
    Chirag R Parikh
    Section of Nephrology, Yale University and VAMC, 950 Campbell Avenue, Mail Code 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 22:1737-47. 2011
    ..In conclusion, urine IL-18 and urine NGAL, but not plasma NGAL, associate with subsequent AKI and poor outcomes among children undergoing cardiac surgery...
  17. doi request reprint A point-of-care device for acute kidney injury: a fantastic, futuristic, or frivolous 'measure'?
    Chirag R Parikh
    Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Kidney Int 76:8-10. 2009
    ..Also discussed are the patient, provider, and financial outcomes that ought to be evaluated before the POC test becomes available for clinical use...
  18. ncbi request reprint Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit
    Chirag R Parikh
    Yale University, Section of Nephrology, 950 Campbell Avenue, Box 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 16:3046-52. 2005
    ..Urinary IL-18 levels can be used for the early diagnosis of AKI. Urine IL-18 levels also predict the mortality of patients who have ARDS and are in the intensive care unit...
  19. doi request reprint Acute kidney injury: Better biomarkers and beyond
    C R Parikh
    Section of Nephrology, Yale University School of Medicine and Veterans Affairs Medical Center, West Haven, Connecticut, USA
    Kidney Int 73:801-3. 2008
    ..We review fundamental epidemiologic concepts for testing the new early acute kidney injury biomarkers in clinical care...
  20. pmc IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation
    Isaac E Hall
    Department of Medicine, Yale University, West Haven, CT 06516, USA
    J Am Soc Nephrol 21:189-97. 2010
    ..In summary, urinary NGAL and IL-18 are early, noninvasive, accurate predictors of both the need for dialysis within the first week of kidney transplantation and 3-mo recovery of graft function...
  21. pmc Serum vasopressin response in patients with intradialytic hypotension: a pilot study
    Mira Rho
    Yale University School of Medicine, New Haven, CT 06520, USA
    Clin J Am Soc Nephrol 3:729-35. 2008
    ..Arginine vasopressin (AVP), an endogenous hormone with vasopressor properties, may be inadequately secreted during episodes of intradialytic hypotension (IDH)...
  22. ncbi request reprint Pharmacology
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Kidney Dis 46:1129-39. 2005
  23. pmc Commonly used surrogates for baseline renal function affect the classification and prognosis of acute kidney injury
    Edward D Siew
    Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Kidney Int 77:536-42. 2010
    ..Our study found that commonly used surrogates for baseline serum creatinine result in bi-directional misclassification of the incidence and prognosis of acute kidney injury in a hospital setting...
  24. pmc Diagnostic value of urine microscopy for differential diagnosis of acute kidney injury in hospitalized patients
    Mark A Perazella
    Section of Nephrology, Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 3:1615-9. 2008
    ..Urine microscopy is the oldest and one of the most commonly used tests for differential diagnosis of acute kidney injury (AKI), but its performance has not been adequately studied in the setting of AKI...
  25. doi request reprint Long-term stability of serum sodium in hemodialysis patients
    Aldo J Peixoto
    Medical Service, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Blood Purif 29:264-7. 2010
    ..The aim of this study was to delineate the long-term variability of serum sodium in HD patients...
  26. pmc Urine microscopy is associated with severity and worsening of acute kidney injury in hospitalized patients
    Mark A Perazella
    Section of Nephrology, Yale University, New Haven, CT 06520 8029, USA
    Clin J Am Soc Nephrol 5:402-8. 2010
    ..Although urine microscopy is useful to differentiate AKI, its role in predicting adverse clinical outcomes has not been well described...
  27. doi request reprint Urinary biomarkers for acute kidney injury: perspectives on translation
    Steven G Coca
    Section of Nephrology, VAMC and Yale University School of Medicine, Clinical Epidemiology Research Center, West Haven, CT 06516, USA
    Clin J Am Soc Nephrol 3:481-90. 2008
    ..It is likely that a panel of biomarkers, rather than a single biomarker, will be needed to perform extremely well in these three situations...
  28. doi request reprint Renal ultrasonography in the evaluation of acute kidney injury: developing a risk stratification framework
    Adam Licurse
    Yale University, New Haven, CT 06520 8025, USA
    Arch Intern Med 170:1900-7. 2010
    ..In adult inpatients with acute kidney injury (AKI), clinicians routinely order a renal ultrasonography (RUS) study. It is unclear how often this test provides clinically useful information...
  29. ncbi request reprint Contribution of acute kidney injury toward morbidity and mortality in burns: a contemporary analysis
    Steven G Coca
    Clinical Epidemiology Research Center, Veterans Affairs Medical Center, West Haven, CT 06516, USA
    Am J Kidney Dis 49:517-23. 2007
    ..It is not known whether milder forms of AKI have prognostic importance in burns...
  30. doi request reprint Acute kidney injury in cirrhosis
    Guadalupe Garcia-Tsao
    Section of Digestives Diseases, Yale University School of Medicine, New Haven, CT, USA
    Hepatology 48:2064-77. 2008
    ..Vasoconstrictors are useful bridging therapies in HRS. Ultimately, liver transplantation is indicated in otherwise reasonable candidates in whom AKI does not resolve with specific therapy...
  31. ncbi request reprint Urinary tract infections after renal transplantation: a retrospective review at two US transplant centers
    Peale Chuang
    Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Clin Transplant 19:230-5. 2005
    ..We conclude UTIs may be associated with an increased mortality risk in renal transplant recipients. Prevention of UTIs in high-risk renal transplant patients or those with recurrent UTIs may possibly decrease post-transplant mortality...
  32. ncbi request reprint Urinary interleukin-18 is a marker of human acute tubular necrosis
    Chirag R Parikh
    Department of Medicine, University of Colorado School of Medicine, Denver, CO 80262, USA
    Am J Kidney Dis 43:405-14. 2004
    ..Interleukin-18 (IL-18) is a mediator of ischemic acute tubular necrosis (ATN) in mice...
  33. doi request reprint Screening for kidney diseases: older measures versus novel biomarkers
    Ian Wu
    Section of Nephrology, Yale University, New Haven, Connecticut, USA
    Clin J Am Soc Nephrol 3:1895-901. 2008
    ..The limitations of creatinine in screening for kidney diseases in specific patient populations as well as new potential biomarkers that are actively being researched are discussed in this review...
  34. pmc Renal impairment predicts long-term mortality risk after acute myocardial infarction
    Grace L Smith
    Section of Nephrology, Yale University and VAMC, 950 Campbell Avenue, Mail Code 151B, Building 35 A, Room 219, West Haven, CT 06516, USA
    J Am Soc Nephrol 19:141-50. 2008
    ..Associations with estimated GFR demonstrated similar trends. In conclusion, renal function in hospitalized patients with AMI is an important and consistent predictor of mortality for up to 10 yr...
  35. ncbi request reprint Renal dysfunction in allogeneic hematopoietic cell transplantation
    Chirag R Parikh
    Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado School of Medicine, Denver, Colorado, USA
    Kidney Int 62:566-73. 2002
    ..We have previously shown an overall 21% incidence of severe acute renal failure in patients undergoing autologous HCT. The present study evaluated renal dysfunction in patients undergoing allogeneic HCT...
  36. doi request reprint Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis
    Sri G Yarlagadda
    Section of Nephrology, University of Kansas Medical Center, Kansas City, KS, USA
    Nephrol Dial Transplant 24:1039-47. 2009
    ..We conducted a systematic review and meta-analysis to precisely estimate these relationships...
  37. doi request reprint New biomarkers of acute kidney injury
    Chirag R Parikh
    Section of Nephrology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA
    Crit Care Med 36:S159-65. 2008
    ....
  38. doi request reprint Long-term clinical consequences of acute kidney injury in the HIV-infected
    Andy I Choi
    Department of Medicine, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Kidney Int 78:478-85. 2010
    ..Additionally, AKI affected almost one of six patients with HIV who survived at least 90 days following discharge...
  39. ncbi request reprint Impact of chronic kidney disease on health-related quality-of-life improvement after coronary artery bypass surgery
    Chirag R Parikh
    Clinical Epidemiology Research Center, Veterans Affairs Medical Center, West Haven, CT 06516, USA
    Arch Intern Med 166:2014-9. 2006
    ..Little is known about the impact of chronic kidney disease (CKD) on health-related quality-of-life outcomes after coronary artery bypass grafting (CABG)...
  40. pmc The impact of hepatitis C virus coinfection on HIV-related kidney disease: a systematic review and meta-analysis
    Christina M Wyatt
    Department of Medicine, Division of Nephrology, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    AIDS 22:1799-807. 2008
    ..In the era of antiretroviral therapy, non-AIDS complications such as kidney disease are important contributors to morbidity and mortality...
  41. doi request reprint Long-term prognosis of acute kidney injury after acute myocardial infarction
    Chirag R Parikh
    Department of Medicine, Clinical Epidemiology Research Center, Veterans Affairs Medical Center, West Haven, Connecticut 06516, USA
    Arch Intern Med 168:987-95. 2008
    ..Acute kidney injury (AKI) is a common complication during hospitalization and is an accepted risk factor for in-hospital mortality. However, the association of severity of AKI with the long-term risk of death is not well defined...
  42. ncbi request reprint The prognostic importance of a small acute decrement in kidney function in hospitalized patients: a systematic review and meta-analysis
    Steven G Coca
    Clinical Epidemiology Research Center, VA Connecticut Healthcare System, West Haven, USA
    Am J Kidney Dis 50:712-20. 2007
    ..Recently, acute kidney injury defined by small changes in serum creatinine levels was associated with worse short-term outcomes; however, the precision and variability of this association was not fully explored...
  43. ncbi request reprint Comparison of renal injury in myeloablative autologous, myeloablative allogeneic and non-myeloablative allogeneic haematopoietic cell transplantation
    Robert W Schrier
    Department of Medicine, The University of Colorado School of Medicine, Denver, CO, USA
    Nephrol Dial Transplant 20:678-83. 2005
  44. ncbi request reprint Underrepresentation of renal disease in randomized controlled trials of cardiovascular disease
    Steven G Coca
    Clinical Epidemiology Research Center, Veterans Affairs Medical Center, West Haven, Conn 06516, USA
    JAMA 296:1377-84. 2006
    ..Patients with renal disease are at high risk for cardiovascular mortality. Determining which interventions best offset this risk remains a health priority...
  45. ncbi request reprint When heparin causes thrombosis: significance, recognition, and management of heparin-induced thrombocytopenia in dialysis patients
    John Jae Young Chang
    Section of Nephrology, Clinical Epidemiology Research Center, VA Connecticut Health Care System and Yale University, West Haven, Connecticut 06516, USA
    Semin Dial 19:297-304. 2006
    ..This review discusses the epidemiology, pathogenesis, clinical features, diagnosis, and treatment of HIT, with special emphasis on concepts relevant to the care of dialysis patients...
  46. pmc Prevention and treatment of acute kidney injury in patients undergoing cardiac surgery: a systematic review
    Meyeon Park
    Clinical Epidemiology Research Center, Veterans Affairs Medical Center, West Haven, Conn 06516, USA
    Am J Nephrol 31:408-18. 2010
    ..We conducted a systematic review of randomized controlled trials for strategies to prevent or treat AKI in cardiac surgery...
  47. pmc Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis
    Steven G Coca
    Section of Nephrology, Yale University, West Haven, CT 06516, USA
    Am J Kidney Dis 53:961-73. 2009
    ..Acute kidney injury (AKI) is common in hospitalized patients. The impact of AKI on long-term outcomes is controversial...
  48. pmc Searching for genes that matter in acute kidney injury: a systematic review
    Jonathan C T Lu
    Yale University School of Medicine, New Haven, Connecticut, USA
    Clin J Am Soc Nephrol 4:1020-31. 2009
    ..Another factor that likely affects risk is intrinsic genetic variability. Therefore, a systematic review of studies was performed that related the development or prognosis of AKI to genetic variation...
  49. pmc Marked variation in the definition and diagnosis of delayed graft function: a systematic review
    Sri G Yarlagadda
    Section of Nephrology, Yale University and VAMC, 950 Campbell Ave, Mail Code 151B, Bldg 35 A, Room 219, West Haven, CT 06516, USA
    Nephrol Dial Transplant 23:2995-3003. 2008
    ..DGF increases morbidity after transplantation, prolongs hospitalization and may lead to premature graft failure. Various definitions of DGF are used in the literature without a uniformly accepted technique to identify DGF...
  50. pmc Reversal of end-stage renal disease after aortic dissection using renal artery stent: a case report
    Andrew S Weiss
    Department of Medicine, University of Colorado Health Sciences Center, 4200 East Ninth Ave, Box B177, Denver, CO 80262, USA
    BMC Nephrol 5:7. 2004
    ..We describe a patient who benefited from endovascular repair of renal artery stenosis caused by a dissection flap, which resulted in reversal of his end-stage renal disease (ESRD)...
  51. ncbi request reprint Effects of warfarin on blood pressure in men with diabetes and hypertension--a longitudinal study
    Mary Ann Lim
    Department of Medicine, University of Connecticut School of Medicine, Farmington, CT, USA
    J Clin Hypertens (Greenwich) 9:256-8. 2007
    ..The results demonstrate that warfarin therapy at conventional doses does not increase systolic blood pressure or pulse pressure in patients with diabetes and hypertension...
  52. ncbi request reprint Urinary interleukin-18 is an acute kidney injury biomarker in critically ill children
    Kimberly K Washburn
    Renal Section, Baylor College of Medicine, Houston, TX, USA
    Nephrol Dial Transplant 23:566-72. 2008
    ..In the present study, the relationship between uIL-18 and AKI was determined in a heterogeneous group of critically ill children...
  53. ncbi request reprint Comparison of ARF after myeloablative and nonmyeloablative hematopoietic cell transplantation
    Chirag R Parikh
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Kidney Dis 45:502-9. 2005
    ..The present study compares the incidence of ARF between patients undergoing concurrent myeloablative and nonmyeloablative HCT in the same period at the same institution...
  54. ncbi request reprint Characterization of acute liver failure and development of a continuous risk of death staging system in children
    Edwin Liu
    Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Children s Hospital and University of Colorado Health Sciences Center, 1056 East 19th Avenue, Box B290, Denver, CO 80218 1088, USA
    J Hepatol 44:134-41. 2006
    ..There is currently no system for staging severity of ALF in children. The aim of this study was to characterize pediatric ALF in a tertiary hospital and to derive a scoring system to stratify severity of ALF based on predicted mortality...
  55. pmc Evaluation and initial management of acute kidney injury
    Jonathan Himmelfarb
    Division of Nephrology, Maine Medical Center, 22 Bramhall Street, Portland, ME 04102, USA
    Clin J Am Soc Nephrol 3:962-7. 2008
    ....
  56. pmc Ascertainment and epidemiology of acute kidney injury varies with definition interpretation
    Michael Zappitelli
    Montreal Children s Hospital, 2300 Tupper, Room E 222, Montreal, QC H3H1P3, Canada
    Clin J Am Soc Nephrol 3:948-54. 2008
    ..Differences in defining acute kidney injury (AKI) may impact incidence ascertainment. We assessed the effects of different AKI definition interpretation methods on epidemiology ascertainment...
  57. ncbi request reprint Kidney disease is an independent risk factor for adverse fetal and maternal outcomes in pregnancy
    Michael J Fischer
    Department of Internal Medicine, Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Kidney Dis 43:415-23. 2004
    ..The goal of this study is to better describe the population of women with kidney disease and provide a contemporary assessment of their risk for adverse events caused by kidney disease after adjustment for other contributing factors...
  58. ncbi request reprint Uncomplicated acute renal failure and hospital resource utilization: a retrospective multicenter analysis
    Michael J Fischer
    Department of Internal Medicine, University of Illinois Medical Center Veterans Administration Medical Center, Chicago, IL, USA
    Am J Kidney Dis 46:1049-57. 2005
    ..The goal of this study is to characterize the costs and lengths of stay (LOSs) incurred by hospitalized patients with uncomplicated ARF and their important determining factors...
  59. ncbi request reprint Kidney transplantation for systemic sclerosis improves survival and may modulate disease activity
    Eric M Gibney
    Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, CO, USA
    Am J Transplant 4:2027-31. 2004
    ..Transplantation may be associated with an improvement in systemic manifestations of disease. Despite suboptimal graft survival, kidney transplant should be considered the treatment of choice in ESRD due to SS...
  60. doi request reprint Cardiovascular disease and hypertension risk in living kidney donors: an analysis of health administrative data in Ontario, Canada
    Amit X Garg
    1Division of Nephrology, University of Western Ontario, London, Canada
    Transplantation 86:399-406. 2008
    ..Risk estimates in the literature are variable, and most studies did not use a healthy control group to assess outcomes attributable to donation...
  61. ncbi request reprint Chronic renal failure after transplantation of a nonrenal organ
    Chirag R Parikh
    N Engl J Med 349:2563-5; author reply 2563-5. 2003
  62. ncbi request reprint Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy
    Tomas Berl
    University of Colorado Medical School, Denver, Colorado, USA
    Ann Intern Med 138:542-9. 2003
    ..The primary outcomes of the Irbesartan Diabetic Nephropathy Trial were doubling of serum creatinine levels, end-stage renal disease, and death from any cause...
  63. ncbi request reprint Vasopressin, not octreotide, may be beneficial in the treatment of hepatorenal syndrome: a retrospective study
    Tyree H Kiser
    Department of Clinical Pharmacy, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, USA
    Nephrol Dial Transplant 20:1813-20. 2005
    ..This study aims to evaluate the effects of AVP and OCT on renal function, systemic haemodynamics and clinical outcomes in HRS...
  64. ncbi request reprint Cardiovascular medication use after coronary bypass surgery in patients with renal dysfunction: a national Veterans Administration study
    Eric M Gibney
    Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, Colorado, USA
    Kidney Int 68:826-32. 2005
    ..We also examined associations between cardiovascular medication use and mortality at 6 months...
  65. ncbi request reprint Acute renal failure after nonmyeloablative hematopoietic cell transplantation
    Chirag R Parikh
    Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Am Soc Nephrol 15:1868-76. 2004
    ..The data are also suggestive that ARF may contribute to mortality after nonmyeloablative HCT...
  66. ncbi request reprint Congenital renal agenesis: case-control analysis of birth characteristics
    Chirag R Parikh
    Division of Nephrology, Department of Preventive Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Kidney Dis 39:689-94. 2002
    ..This condition appears to have a multifactorial cause, with a combination of genetic and environmental factors. Further research is needed to show a better understanding of these risk factors...
  67. ncbi request reprint Living kidney donors requiring transplantation: focus on African Americans
    Eric M Gibney
    Division of Nephrology, Hume Lee Transplant Center, Virginia Commonwealth University, Richmond, VA, USA
    Transplantation 84:647-9. 2007
    ..Although AAs comprised 14.3% of all living kidney donors, they constituted 44% of donors reaching the waiting list (P<0.001). These data provide indirect evidence that the risk of kidney failure may be exaggerated in AA donors...
  68. ncbi request reprint Evaluating the ROC performance of markers for future events
    Margaret S Pepe
    Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M2 B500, Seattle, WA 98109, USA
    Lifetime Data Anal 14:86-113. 2008
    ..Applications to two datasets are presented...
  69. pmc Uncomplicated acute renal failure and post-hospital care: a not so uncomplicated illness
    Michael J Fischer
    Department of Internal Medicine Section of Nephrology, Jesse Brown VA Medical Center and University of Illinois Medical Center, Chicago, IL 60612 7315, USA
    Am J Nephrol 28:523-30. 2008
    ..The goal of this study was to characterize the post-hospital care requirements incurred by patients with uncomplicated ARF and to determine its important influencing factors...
  70. doi request reprint Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis
    Roland Schmitt
    Department of Nephrology, Hannover Medical School, Hannover, Germany
    Am J Kidney Dis 52:262-71. 2008
    ..The prevalence of elderly individuals continues to increase over time, as does the incidence of acute kidney injury (AKI). However, it is not known whether age is an important prognostic predictor for renal recovery after an episode of AKI...
  71. ncbi request reprint Screening for microalbuminuria simplified by urine specific gravity
    Chirag R Parikh
    Nassau County Medical Center, State University of New York at Stony Brook, East Meadow, USA
    Am J Nephrol 22:315-9. 2002
    ..We determined the relation between urine-specific gravity (Usg) and urine creatinine (Ucr) so that Ucr can be derived from Usg to correct for albumin concentration in the urine which is influenced by urine volume...

Research Grants6

  1. Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney Injury
    Chirag R Parikh; Fiscal Year: 2010
    ..The ultimate findings of this study will pave the way for larger multi-center studies of these biomarkers in other clinical conditions and for interventional clinical trials to prevent or to treat AKI. ..
  2. Novel Biomarkers in Cardiac Surgery to Detect Acute Kidney Injury
    Chirag Parikh; Fiscal Year: 2009
    ..The ultimate findings of this study will pave the way for larger multi-center studies of these biomarkers in other clinical conditions and for interventional clinical trials to prevent or to treat AKI. ..