Research Topics
| Elijah PaintsilSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Virologic and Host Risk Factors for Mother-to-Child Transmission of HIVShanmugapriya Selvaraj
Departments of Pediatrics and Pharmacology, Yale School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520, USA
Curr HIV Res 11:93-101. 2013..Understanding the mechanisms, timing, and viral and host factors associated with MTCT of HIV will help to identify appropriate interventions and suitable antiretroviral chemoprophylaxis regimens to reduce or eliminate MTCT...
Update on recent guidelines for the management of urinary tract infections in children: the shifting paradigmElijah Paintsil
Departments of Pediatrics and Pharmacology, Yale School of Medicine, New Haven, Connecticut 06520 8064, USA
Curr Opin Pediatr 25:88-94. 2013..This review focuses on new additions to the literature on management of UTI from January 2011 to September 2012...
Determinants of individual variation in intracellular accumulation of anti-HIV nucleoside analog metabolitesElijah Paintsil
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
Antimicrob Agents Chemother 55:895-903. 2011....
Pediatric community-acquired methicillin-resistant Staphylococcus aureus infection and colonization: trends and managementElijah Paintsil
Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Curr Opin Pediatr 19:75-82. 2007..The scourge of community-acquired methicillin-resistant Staphylococcus aureus in pediatrics continues unabated. This review provides information on changes in epidemiology, therapeutic considerations, and measures to control the epidemic...
Survival of hepatitis C virus in syringes: implication for transmission among injection drug usersElijah Paintsil
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Infect Dis 202:984-90. 2010..We hypothesized that the high prevalence of hepatitis C virus (HCV) among injection drug users might be due to prolonged virus survival in contaminated syringes...
Hepatitis C virus infection among drug injectors in St Petersburg, Russia: social and molecular epidemiology of an endemic infectionElijah Paintsil
Yale University School of Medicine, New Haven, CT 06520, USA
Addiction 104:1881-90. 2009..To understand the epidemiology and transmission patterns of hepatitis C virus (HCV), the predominant blood borne-pathogen infecting injection drug users (IDUs), in a part of the former Soviet Union...
Absolute CD4+ T-lymphocyte count as a surrogate marker of pediatric human immunodeficiency virus disease progressionElijah Paintsil
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
Pediatr Infect Dis J 27:629-35. 2008..We assessed the use of absolute CD4+ T-lymphocyte count as a surrogate marker of pediatric HIV disease progression...
Update on successes and challenges regarding mother-to-child transmission of HIVElijah Paintsil
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Curr Opin Pediatr 21:94-101. 2009..This review outlines the successes made and the challenges that remain...
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profileGuangwei Yang
Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
Antimicrob Agents Chemother 53:4640-6. 2009..g., more than 50-fold resistance) will be difficult to develop. The previously observed 130-fold resistance of the virus with P119S/T165A/M184V to 4'-Ed4T may be partly due to mutations both in the RT sequence and outside the RT sequence...
Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analogElijah Paintsil
Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, SHM B226, New Haven, CT 06520, USA
Antimicrob Agents Chemother 51:3870-9. 2007..4'-Ed4T is a promising antiviral candidate for HIV type 1 chemotherapy...
The contribution of HIV fitness to the evolution pattern of reverse transcriptase inhibitor resistanceElijah Paintsil
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Med Virol 78:425-30. 2006..We also surmise that drug resistance and fitness are competing forces underlying the emergence of nevirapine resistant mutants 103N and 181C...
Care and management of the infant of the HIV-1-infected motherElijah Paintsil
Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520 8064, USA
Semin Perinatol 31:112-23. 2007..These are discussed under four case scenarios that obstetric and pediatric providers frequently encounter in their practices...
Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from cultureElijah Paintsil
Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA
AIDS Res Ther 6:5. 2009..Therefore, a better indicator of the pharmacodynamic property of an inhibitor. The persistence of anti-HIV activity assay may complement in vitro potency assays to better predict in vivo performance of nucleoside analogs...
Prevalence and pattern of disclosure of HIV status in HIV-infected children in GhanaStacey Kallem
Department of Pediatrics and Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
AIDS Behav 15:1121-7. 2011..The low prevalence of disclosure underscores the need for a systematic and a staged approach in disclosing HIV status to infected children in resource limited countries...
Performance of Clinical Criteria for Screening of Possible Antiretroviral Related Mitochondrial Toxicity in HIV-Infected Children in AccraAllison Langs-Barlow
Department of Pediatrics, Yale School of Medicine, New Haven, CT 06520, USA
AIDS Res Treat 2013:249171. 2013..However, as indicators of HAART exposure are associated with (+) EPF, it may be a candidate for prospective study of possible HAART related MT in resource-poor settings...
Analysis of deoxyribonucleotide pools in human cancer cell lines using a liquid chromatography coupled with tandem mass spectrometry techniqueWei Zhang
Department of Pharmacology, Section of Medical Oncology, Yale School of Medicine, New Haven, CT 06520, USA
Biochem Pharmacol 82:411-7. 2011..This LC/MS/MS assay is simple, fast, and sensitive, and it represents a significant advance over previously published methodologies...
Competitive fitness of nevirapine-resistant human immunodeficiency virus type 1 mutantsJennifer A Collins
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Virol 78:603-11. 2004....
