STEPHANIE S O'MALLEY

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Smoking cessation is followed by increases in serum bilirubin, an endogenous antioxidant associated with lower risk of lung cancer and cardiovascular disease
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale School of Medicine, New Haven, CT Yale Comprehensive Cancer Center, New Haven, CT
    Nicotine Tob Res 16:1145-9. 2014
  2. ncbi request reprint Efficacy of extended-release naltrexone in alcohol-dependent patients who are abstinent before treatment
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
    J Clin Psychopharmacol 27:507-12. 2007
  3. pmc Naltrexone alone and with sertraline for the treatment of alcohol dependence in Alaska natives and non-natives residing in rural settings: a randomized controlled trial
    STEPHANIE S O'MALLEY
    Yale University School of Medicine, Connecticut Mental Health Center, S202, 34 Park Street, New Haven, CT 06519, USA
    Alcohol Clin Exp Res 32:1271-83. 2008
  4. ncbi request reprint Naltrexone and cognitive behavioral coping skills therapy for the treatment of alcohol drinking and eating disorder features in alcohol-dependent women: a randomized controlled trial
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 31:625-34. 2007
  5. ncbi request reprint Initial and maintenance naltrexone treatment for alcohol dependence using primary care vs specialty care: a nested sequence of 3 randomized trials
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Arch Intern Med 163:1695-704. 2003
  6. ncbi request reprint A controlled trial of naltrexone augmentation of nicotine replacement therapy for smoking cessation
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven 06519, USA
    Arch Intern Med 166:667-74. 2006
  7. pmc Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Int J Neuropsychopharmacol 12:589-97. 2009
  8. pmc Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 107:221-9. 2010
  9. doi request reprint Characteristics of older adult problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 22:241-54. 2006
  10. pmc Factor structure and validity of the Medication Adherence Questionnaire (MAQ) with cigarette smokers trying to quit
    Benjamin A Toll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Nicotine Tob Res 9:597-605. 2007

Research Grants

  1. Naltrexone for Heavy Drinking in Young Adults
    STEPHANIE S O apos MALLEY; Fiscal Year: 2010
  2. Trajectories of Drinking and Compliance in the COMBINE Study
    STEPHANIE S contact O apos MALLEY; Fiscal Year: 2010
  3. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2002
  4. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2003
  5. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2004
  6. Naltrexone for Heavy Drinking in Young Adults
    STEPHANIE O MALLEY; Fiscal Year: 2009
  7. Ethanol metabolites for monitoring drinking in clinical trials.
    STEPHANIE S contact O apos MALLEY; Fiscal Year: 2010
  8. Naltrexone for Heavy Drinking in Young Adults
    STEPHANIE O MALLEY; Fiscal Year: 2009
  9. Trajectories of Drinking and Compliance in the COMBINE Study
    STEPHANIE O MALLEY; Fiscal Year: 2009
  10. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2001

Detail Information

Publications72

  1. ncbi request reprint Smoking cessation is followed by increases in serum bilirubin, an endogenous antioxidant associated with lower risk of lung cancer and cardiovascular disease
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale School of Medicine, New Haven, CT Yale Comprehensive Cancer Center, New Haven, CT
    Nicotine Tob Res 16:1145-9. 2014
    ..This study evaluates the effects of smoking cessation on bilirubin levels...
  2. ncbi request reprint Efficacy of extended-release naltrexone in alcohol-dependent patients who are abstinent before treatment
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
    J Clin Psychopharmacol 27:507-12. 2007
    ..In conclusion, XR-NTX 380 mg prolonged abstinence and reduced the number of heavy drinking days and drinking days in patients who were abstinent for as few as 4 days before treatment initiation...
  3. pmc Naltrexone alone and with sertraline for the treatment of alcohol dependence in Alaska natives and non-natives residing in rural settings: a randomized controlled trial
    STEPHANIE S O'MALLEY
    Yale University School of Medicine, Connecticut Mental Health Center, S202, 34 Park Street, New Haven, CT 06519, USA
    Alcohol Clin Exp Res 32:1271-83. 2008
    ..An exploratory aim examined whether the Asn40Asp polymorphism of the mu-opioid receptor gene (OPRM1) predicted response to naltrexone, as had been reported in Caucasians...
  4. ncbi request reprint Naltrexone and cognitive behavioral coping skills therapy for the treatment of alcohol drinking and eating disorder features in alcohol-dependent women: a randomized controlled trial
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 31:625-34. 2007
    ..This study investigated the safety and efficacy of naltrexone in combination with Cognitive Behavioral Coping Skills Therapy (CBCST) in a sample of alcohol-dependent women, some with comorbid eating pathology...
  5. ncbi request reprint Initial and maintenance naltrexone treatment for alcohol dependence using primary care vs specialty care: a nested sequence of 3 randomized trials
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Arch Intern Med 163:1695-704. 2003
    ..This study tests naltrexone and primary care management (PCM) vs naltrexone and cognitive behavior therapy (CBT) and tests naltrexone maintenance among patients who respond to an initial course of naltrexone combined with PCM vs CBT...
  6. ncbi request reprint A controlled trial of naltrexone augmentation of nicotine replacement therapy for smoking cessation
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven 06519, USA
    Arch Intern Med 166:667-74. 2006
    ..Thus, this study evaluated whether naltrexone hydrochloride augmentation of nicotine patch therapy improves smoking abstinence and reduces postcessation weight gain more than nicotine patch therapy alone and at what dose...
  7. pmc Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation
    STEPHANIE S O'MALLEY
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Int J Neuropsychopharmacol 12:589-97. 2009
    ..Given its efficacy and favourable side-effect profile, the 25-mg dose should be considered for future studies of combination therapy...
  8. pmc Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 107:221-9. 2010
    ..It was hypothesized that different treatments may affect different trajectories of drinking...
  9. doi request reprint Characteristics of older adult problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    J Gambl Stud 22:241-54. 2006
    ..Given data from older adult problem gamblers in treatment, we hypothesized that older as compared with younger adult problem gamblers calling a gambling helpline would be less likely to report gambling-related problems...
  10. pmc Factor structure and validity of the Medication Adherence Questionnaire (MAQ) with cigarette smokers trying to quit
    Benjamin A Toll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Nicotine Tob Res 9:597-605. 2007
    ..Information obtained with this questionnaire could be used to counsel patients regarding the importance of medication adherence...
  11. pmc Sex-specific differences in GABA(A) -benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving
    Irina Esterlis
    Department of Psychiatry, Yale University and the VACHS, West Haven, CT 06516, USA
    Addict Biol 18:370-8. 2013
    ....
  12. pmc Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment response
    Ralitza Gueorguieva
    Department of Biostatistics, Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Addict Behav 38:2119-27. 2013
    ..The results of these analyses may suggest approaches to improving adherence in order to ultimately improve treatment outcome...
  13. pmc Baseline trajectories of drinking moderate acamprosate and naltrexone effects in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 35:523-31. 2011
    ....
  14. pmc Sex differences in availability of β2*-nicotinic acetylcholine receptors in recently abstinent tobacco smokers
    Kelly P Cosgrove
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Arch Gen Psychiatry 69:418-27. 2012
    ..Sex differences in availability of nicotinic acetylcholine receptors containing the β(2) subunit (β(2)*-nAChRs) may underlie differential nicotine and tobacco smoking effects and related behaviors in women vs men...
  15. pmc A preliminary investigation of varenicline for heavy drinking smokers
    Lisa M Fucito
    Department of Psychiatry, CMHC S200, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 215:655-63. 2011
    ..However, varenicline has not been tested in heavy drinkers, and it remains to be determined whether varenicline could reduce alcohol craving and consumption in smokers who are trying to quit smoking...
  16. pmc Comparing gain- and loss-framed messages for smoking cessation with sustained-release bupropion: a randomized controlled trial
    Benjamin A Toll
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Psychol Addict Behav 21:534-44. 2007
    ..These data suggest that gain-framed messages may be more persuasive than loss-framed messages in promoting early success in smoking cessation for participants who are engaged in treatment...
  17. pmc Correspondence of Interactive Voice Response (IVR) reports of nicotine withdrawal, craving, and negative mood with questionnaire ratings
    Benjamin A Toll
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Nicotine Tob Res 10:1057-64. 2008
    ....
  18. pmc Risk factors for treatment failure in smokers: relationship to alcohol use and to lifetime history of an alcohol use disorder
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Nicotine Tob Res 10:1793-809. 2008
    ..Based on these findings, it appears that risk of any smoking and of relapse was associated primarily with heavy drinking days and a hazardous pattern of use respectively, rather than with moderate drinking...
  19. pmc Subjective reactivity to the first cigarette of the day as a predictor of smoking relapse: a preliminary study
    Benjamin A Toll
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Drug Alcohol Depend 89:302-5. 2007
    ..Moreover, changes in tobacco craving in response to the first cigarette of the day may be a novel predictor of smoking relapse that should be tested in future studies...
  20. ncbi request reprint A human alcohol self-administration paradigm to model individual differences in impaired control over alcohol use
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Exp Clin Psychopharmacol 21:303-14. 2013
    ..Given the variability in response, the impaired control laboratory paradigm may have utility for preliminary tests of novel interventions in future studies and for identifying individual differences in problem-drinking risk...
  21. pmc Effect of a nicotine vaccine on nicotine binding to β2*-nicotinic acetylcholine receptors in vivo in human tobacco smokers
    Irina Esterlis
    Department of Psychiatry, Yale University, New Haven, Conneticut, USA
    Am J Psychiatry 170:399-407. 2013
    ..The authors used [123I]5-I-A-85380 single photon emission computed tomography (SPECT) to evaluate the effect of 3'-AmNic-rEPA on the amount of nicotine that binds to β2*-nAChRs in smokers' brain cortical and subcortical regions...
  22. pmc Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers
    Erica N Peters
    Yale University School of Medicine, Department of Psychiatry, One Long Wharf Drive, Box 18, New Haven, CT 06511, USA
    Addict Behav 37:420-6. 2012
    ..98) nonadherence to medication. Findings suggest that young adult heavy drinkers with co-occurring marijuana use exhibit a high-risk clinical profile and may benefit from interventions that increase adherence to medications...
  23. pmc Varenicline reduces alcohol self-administration in heavy-drinking smokers
    Sherry A McKee
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 66:185-90. 2009
    ..Varenicline, a partial nicotinic agonist with high affinity for the alpha4beta2 nAChR receptor, reduced ethanol intake in rodents. We aimed to test whether varenicline would reduce alcohol consumption and alcohol craving in humans...
  24. pmc Message framing for smoking cessation: the interaction of risk perceptions and gender
    Benjamin A Toll
    Department of Psychiatry, Yale University School of Medicine, New Haven CT 06511, USA
    Nicotine Tob Res 10:195-200. 2008
    ..These findings suggest that message framing interventions for smoking cessation should consider the influence of gender and risk perceptions associated with quitting on the effectiveness of framed interventions...
  25. pmc A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain
    Benjamin A Toll
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Addict Behav 33:173-9. 2008
    ....
  26. pmc A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers
    Andrea H Weinberger
    Program for Research in Smokers with Mental Illness PRISM, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Drug Alcohol Depend 107:188-95. 2010
    ..The primary aim of this study was to determine the safety and efficacy of the monoamine oxidase-B (MAO-B) inhibitor selegiline hydrochloride (SEL, l-Deprenyl; Eldepryl) as an aid for smoking cessation in cigarette smokers...
  27. ncbi request reprint Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis
    STEPHANIE S O'MALLEY
    Yale University School of Medicine, Connecticut Mental Health Center, Substance Abuse Center S202, 34 Park Street, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 160:19-29. 2002
    ..This laboratory study investigated the mechanisms by which the opioid antagonist, naltrexone, reduces the risk of relapse to heavy drinking in individuals with alcohol dependence...
  28. pmc Cigarette smoking predicts differential benefit from naltrexone for alcohol dependence
    Lisa M Fucito
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Biol Psychiatry 72:832-8. 2012
    ..Nevertheless, there is limited research on cigarette smoking as a potential predictor of differential response to pharmacological treatment of alcoholism...
  29. pmc Effect of transdermal nicotine replacement on alcohol responses and alcohol self-administration
    Sherry A McKee
    Department of Psychiatry, Substance Abuse Center CMHC, Yale University School of Medicine, 34 Park St, Suite S 211, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 196:189-200. 2008
    ..Nicotine replacement is commonly used to treat tobacco use in heavy-drinking smokers. However, few studies have examined the effect of nicotine replacement on subjective and physiological responses to alcohol and alcohol drinking behavior...
  30. ncbi request reprint Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking
    Suchitra Krishnan-Sarin
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 34 Park Street, New Haven, CT 06519, USA
    Biol Psychiatry 62:694-7. 2007
    ..The purpose of this study was to examine the interactive effects of family history of alcoholism (FH+, FH-) and naltrexone dose (0, 50, 100 mg/day) on alcohol drinking...
  31. pmc Effect of extended-release naltrexone (XR-NTX) on quality of life in alcohol-dependent patients
    Helen M Pettinati
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Alcohol Clin Exp Res 33:350-6. 2009
    ..2005). A 24-week, randomized, double-blind, placebo-controlled study established the efficacy and safety of XR-NTX in this patient population. In this report, the effect of XR-NTX on quality of life (QOL) was examined...
  32. pmc A pilot study of naltrexone and BASICS for heavy drinking young adults
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Addict Behav 33:1048-54. 2008
    ..Findings from this small pilot study suggest that naltrexone in combination with BASICS represents a promising strategy to reduce heavy drinking among young adults...
  33. pmc Do daily interactive voice response reports of smoking behavior correspond with retrospective reports?
    Benjamin A Toll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychol Addict Behav 19:291-5. 2005
    ..Compliance with the TLFB was superior to compliance with the IVR system. This problem should be addressed if researchers wish to use an IVR system in future smoking cessation clinical trials...
  34. pmc Do patients with alcohol dependence respond to placebo? Results from the COMBINE Study
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, and McLean Hospital, Belmont, Massachusetts, USA
    J Stud Alcohol Drugs 69:878-84. 2008
    ..The purpose of this study was to examine the nature of the effect of placebo medication plus accompanying medical management in the treatment of alcohol dependence...
  35. pmc Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: a randomized trial
    Benjamin A Toll
    Yale University School of Medicine, New Haven, CT 06519, USA Yale Cancer Center, New Haven, CT 06519, USA
    Drug Alcohol Depend 111:200-6. 2010
    ..Given these encouraging findings, we endeavored to test whether minimization of weight gain might translate to better quit outcomes for a population that is particularly concerned about gaining weight upon quitting...
  36. pmc Confirmatory factor analysis of the Minnesota Nicotine Withdrawal Scale
    Benjamin A Toll
    Department of Psychiatry, School of Medicine, Yale University, New Haven, CT 06511, USA
    Psychol Addict Behav 21:216-25. 2007
    ..Confirmatory factor analyses of change scores showed that the MNWS symptoms cohere as a syndrome over time. Future investigators should report a total score using all of the items from the MNWS...
  37. pmc Comparison of expired carbon monoxide and plasma cotinine as markers of cigarette abstinence
    Peter Jatlow
    Yale University School of Medicine, Department of Laboratory Medicine, New Haven, CT 06520 8035, USA
    Drug Alcohol Depend 98:203-9. 2008
    ..These data suggest that while expired CO is a useful and well-established marker in certain contexts, when testing extended abstinence from smoking with non-nicotine medications, cotinine measurements should be preferred...
  38. ncbi request reprint Advances in the use of naltrexone: an integration of preclinical and clinical findings
    STEPHANIE S O'MALLEY
    Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Recent Dev Alcohol 16:217-45. 2003
    ..Ultimately, these lines for research promise to provide critical information that can be used to maximize the efficacy of naltrexone for treating alcoholism...
  39. pmc Correspondence between Interactive Voice Response (IVR) and Timeline Followback (TLFB) reports of drinking behavior
    Benjamin A Toll
    Yale University School of Medicine, Department of Psychiatry, 1 Long Wharf Drive, Box 18, New Haven, CT 06511, and VA Connecticut Healthcare System, USA
    Addict Behav 31:726-31. 2006
    ..However, future studies should focus on improving compliance with IVR in this population...
  40. ncbi request reprint Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial
    James C Garbutt
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill 27599 7160, USA
    JAMA 293:1617-25. 2005
    ..However, adherence to daily oral pharmacotherapy can be problematic, and clinical acceptance and utility of oral naltrexone have been limited...
  41. pmc Menstrual cycle phase at quit date and smoking abstinence at 6 weeks in an open label trial of bupropion
    Carolyn M Mazure
    Women s Health Research at Yale, 135 College Street, Suite 220, New Haven, CT 06510, USA
    Drug Alcohol Depend 114:68-72. 2011
    ..This is the first preliminary study examining whether smoking cessation outcomes vary by menstrual cycle phase of quit date in women receiving a 6-week open trial of sustained release (SR) bupropion...
  42. pmc Minocycline reduced craving for cigarettes but did not affect smoking or intravenous nicotine responses in humans
    Mehmet Sofuoglu
    Yale University, School of Medicine, Department of Psychiatry, West Haven, CT, USA
    Pharmacol Biochem Behav 92:135-40. 2009
    ..These findings provide limited support for the potential use of minocycline as a treatment of nicotine dependence...
  43. ncbi request reprint Characteristics of tobacco-smoking problem gamblers calling a gambling helpline
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Addict 13:471-93. 2004
    ..The high proportion of callers reporting daily tobacco smoking highlights the need for enhanced smoking cessation efforts in problem gamblers...
  44. pmc Alcohol history and smoking cessation in nicotine replacement therapy, bupropion sustained release and varenicline trials: a review
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Alcohol Alcohol 42:196-206. 2007
    ....
  45. pmc Drinking less and drinking smarter: direct and indirect protective strategies in young adults
    Kelly S DeMartini
    Department of Psychiatry, Yale University School of Medicine
    Psychol Addict Behav 27:615-26. 2013
    ..Interventions for young adult drinking may be tailored to patient goals to decrease consumption and/or consequences...
  46. ncbi request reprint A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation
    Tony P George
    Program for Research in Smokers with Mental Illness PRISM, New Haven, Connecticut 06519, USA
    Biol Psychiatry 53:136-43. 2003
    ....
  47. pmc Tobacco quitlines need to assess and intervene with callers' hazardous drinking
    Benjamin A Toll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Alcohol Clin Exp Res 36:1653-8. 2012
    ....
  48. pmc Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence
    Kelly P Cosgrove
    Department of Psychiatry, Yale University School of Medicine and the VACHS, West Haven, CT 06516, USA
    Neuropharmacology 60:1318-25. 2011
    ..This article is part of a Special Issue entitled 'Trends in neuropharmacology: in memory of Erminio Costa'...
  49. pmc Nicotine and food deprivation decrease the ability to resist smoking
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 212:25-32. 2010
    ..Attempts to simultaneously control food intake and smoking may lead to smoking cessation failure. We sought to model this relationship using a human laboratory paradigm of smoking lapse behavior...
  50. pmc Exploring the impact of gender and reproductive status on outcomes in a randomized clinical trial of naltrexone augmentation of nicotine patch
    C Neill Epperson
    University of Pennsylvania School of Medicine, Department of Psychiatry, Philadelphia, PA 19104 3309, USA
    Drug Alcohol Depend 112:1-8. 2010
    ..When used in conjunction with nicotine replacement therapy, naltrexone dose may be important in women...
  51. pmc Beliefs and attitudes about bupropion: implications for medication adherence and smoking cessation treatment
    Lisa M Fucito
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Psychol Addict Behav 23:373-9. 2009
    ..These findings provide preliminary support that positive beliefs and attitudes about bupropion are associated with positive attitudes toward quitting, better treatment adherence, and potentially better treatment response...
  52. pmc Smoke and mirrors: magnified beliefs that cigarette smoking suppresses weight
    Marney A White
    Department of Psychiatry, Yale University School of Medicine, United States
    Addict Behav 32:2200-10. 2007
    ..These findings indicate that eating and weight-concerned smokers may benefit from psychoeducation concerning the relatively modest and temporary ability of nicotine to suppress weight...
  53. pmc A brief 7-day estimate of alcohol consumption for use in smoking cessation clinical trials
    Benjamin A Toll
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Addict Behav 33:1606-9. 2008
    ..To estimate abstinence at baseline and during treatment, however, a more comprehensive period of monitoring may be required...
  54. pmc Targeting cessation: understanding barriers and motivations to quitting among urban adult daily tobacco smokers
    Lisa Rosenthal
    Yale University, School of Public Health, CARE Community Alliance for Research and Engagement, 135 College Street, Suite 200, New Haven, CT 06510, USA
    Addict Behav 38:1639-42. 2013
    ....
  55. ncbi request reprint Correction of urine cotinine concentrations for creatinine excretion: is it useful?
    Peter Jatlow
    Department of Laboratory Medicine, Yale University, New Haven, CT 06520, USA
    Clin Chem 49:1932-4. 2003
  56. pmc Nicotine dependence and psychiatric and substance use comorbidities in a sample of American Indian male veterans
    Daniel L Dickerson
    Yale University, 1 Long Wharf Drive, Box 18, New Haven, CT 06511, USA
    Drug Alcohol Depend 99:169-75. 2009
    ..American Indians and Alaska Natives have the highest rates of nicotine dependence in the U.S. However, studies analyzing associations between nicotine dependence and psychiatric and substance use disorders in these groups have been limited...
  57. pmc Parental history of anxiety and alcohol-use disorders and alcohol expectancies as predictors of alcohol-related problems
    Meghan E Morean
    Department of Psychology, Yale University, 2 Hillhouse Avenue, New Haven, Connecticut 06520, USA
    J Stud Alcohol Drugs 70:227-36. 2009
    ..Expectancies of global positive changes and tension reduction were hypothesized to moderate the influence of parental history of alcoholism and anxiety, respectively...
  58. pmc Modeling the effect of alcohol on smoking lapse behavior
    Sherry A McKee
    Department of Psychiatry, Yale University School of Medicine, Substance Abuse Center CMHC, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 189:201-10. 2006
    ..The primary aim of this project was to examine the role of alcohol use in smoking lapse behavior, as alcohol consumption is a known risk factor for poor smoking cessation outcomes...
  59. pmc Internalizing and externalizing dimensions and alcohol use in first time DWI offenders: indirect effects through coping self-efficacy
    Robert C Schlauch
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, USA
    Psychol Addict Behav 26:133-9. 2012
    ....
  60. ncbi request reprint Concurrent and predictive validity of drug use and psychiatric diagnosis among first-time DWI offenders
    Rebekka S Palmer
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Alcohol Clin Exp Res 31:619-24. 2007
    ..Previous studies have found that driving while intoxicated (DWI) offenders report high rates of substance dependence and other psychiatric disorders...
  61. pmc Smoking status as a clinical indicator for alcohol misuse in US adults
    Sherry A McKee
    Department of Psychiatry, Substance Abuse Center CMHC, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    Arch Intern Med 167:716-21. 2007
    ..Our objective was to investigate smoking status as a clinical indicator for alcohol misuse in a national sample of US adults, following clinical care guidelines for the assessment of these behaviors...
  62. pmc New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials
    Ralitza Gueorguieva
    Department of Epidemiology, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 61:1290-5. 2007
    ..The objective of this study was to identify distinct trajectories of daily drinking over time in two negative clinical trials and to determine whether naltrexone affected the probability to follow a particular trajectory...
  63. pmc Effect of night smoking, sleep disturbance, and their co-occurrence on smoking outcomes
    Erica N Peters
    Department of Psychiatry, Yale University School of Medicine, One Long Wharf Drive, New Haven, CT 06511, USA
    Psychol Addict Behav 25:312-9. 2011
    ..Future smoking cessation treatment might incorporate strategies related to managing these smokers' sleep habits and physiological dependence on nicotine in order to bolster their cessation outcomes...
  64. pmc Ethanol consumption: how should we measure it? Achieving consilience between human and animal phenotypes
    Robert F Leeman
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Addict Biol 15:109-24. 2010
    ....
  65. doi request reprint Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking
    Kelly P Cosgrove
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Neuropsychopharmacology 34:2218-26. 2009
    ..Smoking appears to suppress neuroadaptive changes in DA and 5-HT transporters during acute withdrawal from alcohol...
  66. pmc Altered hypothalamic response to food in smokers
    Paul Y Geha
    John B Pierce Laboratory, New Haven, CT 06519, USA
    Am J Clin Nutr 97:15-22. 2013
    ..Smoking cessation is often followed by weight gain. Eating behaviors and weight change have been linked to the brain response to food, but it is unknown whether smoking influences this response...
  67. pmc Revisiting the factor structure of the questionnaire on smoking urges
    Benjamin A Toll
    Department of Psychiatry, Yale University School of Medicine, 1 Long Wharf Drive, Box 18, New Haven, CT 06511, USA
    Psychol Assess 16:391-5. 2004
    ..The 2nd model was found to fit the data best. Reliability was also tested using values obtained in this 2nd model, and these estimates were found to be reasonably good. Future research directions for the QSU are discussed...
  68. pmc Clinical (nonforensic) application of ethyl glucuronide measurement: are we ready?
    Peter Jatlow
    Yale University School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 34:968-75. 2010
    ..Additional information needed to develop guidelines for optimal clinical utilization of EtG/EtS measurements is discussed...
  69. ncbi request reprint Perceived risks and benefits of smoking cessation: gender-specific predictors of motivation and treatment outcome
    Sherry A McKee
    Department of Psychiatry, Yale University School of Medicine, Substance Abuse Center CMHC, 34 Park Street, S 211, New Haven, CT 06519, USA
    Addict Behav 30:423-35. 2005
    ....
  70. ncbi request reprint Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229 3900, USA
    J Clin Psychopharmacol 23:281-93. 2003
    ..More side effects were noted with the combination of medications than with either medication alone. Naltrexone administration significantly increased plasma acamprosate levels...
  71. pmc The drug effects questionnaire: psychometric support across three drug types
    Meghan E Morean
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Office S 229, 34 Park Street, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 227:177-92. 2013
    ..Thus, the field would benefit from demonstrating the reliability and validity of the DEQ for use across multiple substances...
  72. ncbi request reprint Current pharmacological treatments for nicotine dependence
    Tony P George
    Center for Nicotine and Tobacco Use Research at Yale, Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 109, SAC, New Haven, CT 06519, USA
    Trends Pharmacol Sci 25:42-8. 2004
    ..Several existing medications are being tested as treatments for nicotine dependence and novel investigational agents are under development as effective treatments for nicotine dependence in the 'hard to treat' tobacco user...

Research Grants14

  1. Naltrexone for Heavy Drinking in Young Adults
    STEPHANIE S O apos MALLEY; Fiscal Year: 2010
    ....
  2. Trajectories of Drinking and Compliance in the COMBINE Study
    STEPHANIE S contact O apos MALLEY; Fiscal Year: 2010
    ..The results of these analyses may offer new theoretical and clinical insights into the use of medications and behavioral interventions for the treatment of alcohol addiction. ..
  3. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2002
    ..abstract_text> ..
  4. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2003
    ..abstract_text> ..
  5. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2004
    ..abstract_text> ..
  6. Naltrexone for Heavy Drinking in Young Adults
    STEPHANIE O MALLEY; Fiscal Year: 2009
    ....
  7. Ethanol metabolites for monitoring drinking in clinical trials.
    STEPHANIE S contact O apos MALLEY; Fiscal Year: 2010
    ....
  8. Naltrexone for Heavy Drinking in Young Adults
    STEPHANIE O MALLEY; Fiscal Year: 2009
    ....
  9. Trajectories of Drinking and Compliance in the COMBINE Study
    STEPHANIE O MALLEY; Fiscal Year: 2009
    ..The results of these analyses may offer new theoretical and clinical insights into the use of medications and behavioral interventions for the treatment of alcohol addiction. ..
  10. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2001
    ..abstract_text> ..
  11. NALTREXONE & SSRI THERAPY FOR ALCOHOL DEPENDENCE
    STEPHANIE O MALLEY; Fiscal Year: 2000
    ..abstract_text> ..
  12. NALTREXONE & SEROTONIN REUPTAKE INHIBITOR THERAPY FOR AL
    STEPHANIE O MALLEY; Fiscal Year: 1999
    ..abstract_text> ..