Charla Nich

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Intention-to-treat meets missing data: implications of alternate strategies for analyzing clinical trials data
    Charla Nich
    Department of Psychiatry, Division of Substance Abuse, VA CT healthcare Center 1510, Yale University, 950 Campbell Avenue, West Haven, CT 06515, USA
    Drug Alcohol Depend 68:121-30. 2002
  2. pmc Sex differences in cocaine-dependent individuals' response to disulfiram treatment
    Charla Nich
    Yale University School of Medicine, VA Connecticut Health Care System, West Haven, USA
    Addict Behav 29:1123-8. 2004
  3. ncbi request reprint Naltrexone and disulfiram in patients with alcohol dependence and current depression
    Ismene Petrakis
    Department of Psychiatry, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, West Haven Campus, West Haven, CT 06516, USA
    J Clin Psychopharmacol 27:160-5. 2007
  4. ncbi request reprint Naltrexone and disulfiram in patients with alcohol dependence and comorbid post-traumatic stress disorder
    Ismene L Petrakis
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 60:777-83. 2006
  5. pmc Informal discussions in substance abuse treatment sessions with Spanish-speaking clients
    Wendy Bamatter
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Subst Abuse Treat 39:353-63. 2010
  6. ncbi request reprint The impact of personality disorders on alcohol-use outcomes in a pharmacotherapy trial for alcohol dependence and comorbid Axis I disorders
    Elizabeth Ralevski
    Department of Psychiatry, Yale University School of Medicine, West Haven, Connecticut, USA
    Am J Addict 16:443-9. 2007
  7. pmc A multisite randomized effectiveness trial of motivational enhancement therapy for Spanish-speaking substance users
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06519, USA
    J Consult Clin Psychol 77:993-9. 2009
  8. pmc An exploratory randomized controlled trial of a novel high-school-based smoking cessation intervention for adolescent smokers using abstinence-contingent incentives and cognitive behavioral therapy
    Suchitra Krishnan-Sarin
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, United States
    Drug Alcohol Depend 132:346-51. 2013
  9. pmc Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, USA
    Drug Alcohol Depend 126:224-31. 2012
  10. pmc Evaluating motivational enhancement therapy adherence and competence among Spanish-speaking therapists
    Elizabeth J Santa Ana
    VA CT Healthcare System, Department of Psychiatry, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 103:44-51. 2009

Detail Information

Publications52

  1. pmc Intention-to-treat meets missing data: implications of alternate strategies for analyzing clinical trials data
    Charla Nich
    Department of Psychiatry, Division of Substance Abuse, VA CT healthcare Center 1510, Yale University, 950 Campbell Avenue, West Haven, CT 06515, USA
    Drug Alcohol Depend 68:121-30. 2002
    ..Moreover, regardless of the strategy used, investigators should clearly describe their handling of data from participants who violate the protocol...
  2. pmc Sex differences in cocaine-dependent individuals' response to disulfiram treatment
    Charla Nich
    Yale University School of Medicine, VA Connecticut Health Care System, West Haven, USA
    Addict Behav 29:1123-8. 2004
    ..Reasons for this apparent sex-based response are not clear, but possible mechanisms worthy of greater study include differences in alcohol use by sex as well as differences in dopamine-mediated responses to cocaine and disulfiram...
  3. ncbi request reprint Naltrexone and disulfiram in patients with alcohol dependence and current depression
    Ismene Petrakis
    Department of Psychiatry, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, West Haven Campus, West Haven, CT 06516, USA
    J Clin Psychopharmacol 27:160-5. 2007
    ..In particular, the effect of these medications on alcohol use outcomes and on specific psychiatric symptoms is still unknown in patients with the most common co-occurring disorder, major depression...
  4. ncbi request reprint Naltrexone and disulfiram in patients with alcohol dependence and comorbid post-traumatic stress disorder
    Ismene L Petrakis
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 60:777-83. 2006
    ....
  5. pmc Informal discussions in substance abuse treatment sessions with Spanish-speaking clients
    Wendy Bamatter
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Subst Abuse Treat 39:353-63. 2010
    ..Careful counselor training and supervision in MET may suppress the tendency of counselors to talk informally in sessions...
  6. ncbi request reprint The impact of personality disorders on alcohol-use outcomes in a pharmacotherapy trial for alcohol dependence and comorbid Axis I disorders
    Elizabeth Ralevski
    Department of Psychiatry, Yale University School of Medicine, West Haven, Connecticut, USA
    Am J Addict 16:443-9. 2007
    ..The findings suggest that naltrexone and disulfiram can be safely and effectively used with patients who have comorbid diagnoses of Axis I and Axis II disorders...
  7. pmc A multisite randomized effectiveness trial of motivational enhancement therapy for Spanish-speaking substance users
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06519, USA
    J Consult Clin Psychol 77:993-9. 2009
    ....
  8. pmc An exploratory randomized controlled trial of a novel high-school-based smoking cessation intervention for adolescent smokers using abstinence-contingent incentives and cognitive behavioral therapy
    Suchitra Krishnan-Sarin
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, United States
    Drug Alcohol Depend 132:346-51. 2013
    ....
  9. pmc Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, USA
    Drug Alcohol Depend 126:224-31. 2012
    ....
  10. pmc Evaluating motivational enhancement therapy adherence and competence among Spanish-speaking therapists
    Elizabeth J Santa Ana
    VA CT Healthcare System, Department of Psychiatry, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 103:44-51. 2009
    ....
  11. pmc Combining cognitive behavioral therapy and contingency management to enhance their effects in treating cannabis dependence: less can be more, more or less
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, New Haven, CT 06516, USA
    Addiction 107:1650-9. 2012
    ....
  12. pmc Cognitive function and treatment response in a randomized clinical trial of computer-based training in cognitive-behavioral therapy
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Subst Use Misuse 46:23-34. 2011
    ..Those with higher levels of risk taking completed fewer sessions and homework assignments and had poorer substance use outcomes...
  13. pmc Community program therapist adherence and competence in a motivational interviewing assessment intake session
    Carly J Gibbons
    Yale University School of Medicine, West Haven, Connecticut, USA
    Am J Drug Alcohol Abuse 36:342-9. 2010
    ..The development of psychometrically valid MI integrity measures that can be used for supervision and evaluation and be both sensitive and robust across clinical situations is needed...
  14. pmc Community program therapist adherence and competence in motivational enhancement therapy
    Steve Martino
    Yale University School of Medicine, Department of Psychiatry, Division of Substance Abuse, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 96:37-48. 2008
    ....
  15. pmc Treatment process, alliance and outcome in brief versus extended treatments for marijuana dependence
    Carly J Gibbons
    Yale University, VA CT Healthcare Center 151D, West Haven, CT 06516, USA
    Addiction 105:1799-808. 2010
    ..In this report we present treatment process data, including the fidelity of treatment delivery in the three community-based treatment settings as well as the relationships between treatment process and outcome...
  16. pmc Combining cognitive behavioral therapy with contingency management for smoking cessation in adolescent smokers: a preliminary comparison of two different CBT formats
    Dana A Cavallo
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Am J Addict 16:468-74. 2007
    ..In addition, significantly more participants in the CBT group completed treatment. These preliminary results suggest that when combined with CM, the standard weekly format of CBT is more acceptable to adolescent smokers...
  17. pmc Teaching community program clinicians motivational interviewing using expert and train-the-trainer strategies
    Steve Martino
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Addiction 106:428-41. 2011
    ..The effectiveness of expert-led (EX) and train-the-trainer (TT) strategies was compared to a self-study approach (SS) for teaching clinicians motivational interviewing (MI)...
  18. pmc What is usual about "treatment-as-usual"? Data from two multisite effectiveness trials
    Elizabeth J Santa Ana
    Department of Psychiatry, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    J Subst Abuse Treat 35:369-79. 2008
    ..These data suggest missed opportunities for optimally engaging patients in the early stages of treatment and enhancing substance use outcomes and only moderate success to date of efforts to bridge the gap between research and practice...
  19. pmc Enduring effects of a computer-assisted training program for cognitive behavioral therapy: a 6-month follow-up of CBT4CBT
    Kathleen M Carroll
    Yale University School of Medicine, Division of Substance Abuse, 950 Campbell Avenue, 151D West Haven, CT 06516, USA
    Drug Alcohol Depend 100:178-81. 2009
    ..To evaluate the durability of effects of a computer-assisted version of cognitive behavioral therapy (CBT) as treatment for substance dependence through a 6-month follow-up...
  20. pmc D-Cycloserine attenuates reactivity to smoking cues in nicotine dependent smokers: a pilot investigation
    Elizabeth J Santa Ana
    VA Connecticut Healthcare System, Department of Psychiatry, Division of Substance Abuse, West Haven, CT 06516, USA
    Drug Alcohol Depend 104:220-7. 2009
    ..These findings provide promising support for DCS combined with cue exposure therapy in attenuating conditioned reactivity to smoking cues...
  21. pmc Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Subst Abus 30:306-17. 2009
    ..This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress...
  22. pmc Computer-assisted delivery of cognitive-behavioral therapy for addiction: a randomized trial of CBT4CBT
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Ave, 151D, West Haven, CT 06516, USA
    Am J Psychiatry 165:881-8. 2008
    ..This study evaluated the efficacy of a computer-based version of cognitive-behavioral therapy (CBT) for substance dependence...
  23. ncbi request reprint Naltrexone and disulfiram in patients with alcohol dependence and comorbid psychiatric disorders
    Ismene L Petrakis
    Department of Psychiatry, Yale University, New Haven, Connecticut 06516, USA
    Biol Psychiatry 57:1128-37. 2005
    ..Disulfiram and naltrexone are approved by the Food and Drug Administration (FDA) for the treatment of alcoholism, but these agents have not been rigorously evaluated in dually diagnosed individuals...
  24. pmc Informal discussions in substance abuse treatment sessions
    Steve Martino
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Subst Abuse Treat 36:366-75. 2009
    ....
  25. pmc Site matters: multisite randomized trial of motivational enhancement therapy in community drug abuse clinics
    Samuel A Ball
    Department of Psychiatry, Yale University School of Medicine, APT Foundation, New Haven, CT 06511, USA
    J Consult Clin Psychol 75:556-67. 2007
    ..An independent evaluation of session audiotapes indicated that MET and CAU were highly and comparably discriminable across sites...
  26. ncbi request reprint A cognitive behavioral therapy for alcohol-dependent domestic violence offenders: an integrated substance abuse-domestic violence treatment approach (SADV)
    Caroline J Easton
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine SATU, 1 Long Wharf, New Haven, CT 06511, USA
    Am J Addict 16:24-31. 2007
    ..These data suggest the promise of the SADV group therapy approach for alcohol-dependent males with a history of IPV who present for substance abuse treatment...
  27. ncbi request reprint A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders
    Steve Martino
    Yale Psychosocial Substance Abuse Research Center and Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 101:1479-92. 2006
    ..This pilot study examined the efficacy of a two-session motivational interview adapted for dually diagnosed psychotic and drug-related disordered patients (DDMI) in comparison to a two-session standard psychiatric interview (SI)...
  28. pmc A methodological analysis of randomized clinical trials of computer-assisted therapies for psychiatric disorders: toward improved standards for an emerging field
    Brian D Kiluk
    Departmentof Psychiatry, Yale University School of Medicine, West Haven, CT, USA
    Am J Psychiatry 168:790-9. 2011
    ..However, the extent to which the growing body of randomized trials evaluating computer-assisted therapies meets current standards of methodological rigor for evidence-based interventions is not clear...
  29. pmc Correspondence of motivational enhancement treatment integrity ratings among therapists, supervisors, and observers
    Steve Martino
    Department of Psychiatry, Yale University School ofMedicine, VA Connecticut Healthcare System, 950 Campbell Avenue 151 D, West Haven, CT 06516, USA
    Psychother Res 19:181-93. 2009
    ....
  30. pmc Psychotic spectrum disorders and alcohol abuse: a review of pharmacotherapeutic strategies and a report on the effectiveness of naltrexone and disulfiram
    Ismene L Petrakis
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, 950 Campbell Avenue, Mail Code 116A, West Haven, CT 06516, USA
    Schizophr Bull 32:644-54. 2006
    ..Pharmacotherapeutic strategies should take into account the advantages and disadvantages of each medication. Future directions of pharmacotherapeutic options are also discussed...
  31. pmc Correspondence of motivational interviewing adherence and competence ratings in real and role-played client sessions
    Suzanne E Decker
    New England Mental Illness Research Education and Clinical Centers VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Psychol Assess 25:306-12. 2013
    ..More research is needed to improve the procedures and psychometric strength of treatment integrity assessment based on role-played sessions...
  32. pmc Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: a multisite effectiveness study
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 81:301-12. 2006
    ....
  33. pmc Quality versus quantity: acquisition of coping skills following computerized cognitive-behavioral therapy for substance use disorders
    Brian D Kiluk
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 105:2120-7. 2010
    ..To evaluate the changes over time in quality and quantity of coping skills acquired following cognitive behavioral therapy (CBT), and examine potential mediating effects on substance use outcomes...
  34. pmc Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users
    Sherry A McKee
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06519, USA
    Drug Alcohol Depend 91:97-101. 2007
    ..We investigated the impact of enhancing brief cognitive-behavioral therapy with motivational interviewing techniques for cocaine abuse or dependence, using a focused intervention paradigm...
  35. pmc Mindfulness training for smoking cessation: results from a randomized controlled trial
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Drug Alcohol Depend 119:72-80. 2011
    ..However, MT has not been evaluated for smoking cessation through randomized clinical trials...
  36. pmc Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Arch Gen Psychiatry 61:264-72. 2004
    ..Disulfiram has emerged as a promising treatment for cocaine dependence, but it has not yet been evaluated in general populations of cocaine users...
  37. pmc The use of contingency management and motivational/skills-building therapy to treat young adults with marijuana dependence
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    J Consult Clin Psychol 74:955-66. 2006
    ..Participants assigned to MET/CBT continued to reduce the frequency of their marijuana use through a 6-month follow-up...
  38. pmc Millon Clinical Multiaxial Inventory-III subtypes of opioid dependence: validity and matching to behavioral therapies
    Samuel A Ball
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Consult Clin Psychol 72:698-711. 2004
    ..Predictive validity analyses indicated less symptom improvement for the higher problem subtypes, and patient treatment matching analyses indicated that some subtypes had better outcomes in the no-incentive voucher conditions...
  39. pmc Toward empirical identification of a clinically meaningful indicator of treatment outcome: features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, United States Electronic address
    Drug Alcohol Depend 137:3-19. 2014
    ..Absence of an evidence-based, clinically meaningful index of treatment outcome hinders cross-study evaluations necessary for progress in addiction treatment science...
  40. doi request reprint Risk factors of violence during a 4-week period in a psychiatric outpatient population
    Alec Buchanan
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT Department of Psychology, Simon Fraser University Burnaby, BC, Canada and Mid Sweden University, Sundsvall, Sweden
    J Nerv Ment Dis 201:1021-6. 2013
    ..Instead, increasing cocaine use and increasing social conflict as described by the subject at interview were associated with violence during those weeks. ..
  41. pmc Relationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders
    Brian D Kiluk
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Drug Alcohol Depend 114:169-76. 2011
    ..Little previous research has examined the cognitive or neuropsychological factors that may affect substance users' ability to learn new coping skills in CBT...
  42. doi request reprint Utilizing peer mentorship to engage high recidivism substance-abusing patients in treatment
    Kathlene Tracy
    Community Research and Recovery Program, Department of Psychiatry, New York University School of Medicine, New York, NY 10010, USA
    Am J Drug Alcohol Abuse 37:525-31. 2011
    ..Often high recidivism substance-using patients have difficulty connecting to outpatient treatment contributing to greater functioning disturbances. Approaches to address this problem frequently are staff extensive...
  43. pmc Practice makes progress? Homework assignments and outcome in treatment of cocaine dependence
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 006516, USA
    J Consult Clin Psychol 73:749-55. 2005
    ..These data suggest that the extent to which participants are willing to complete extrasession assignments may be an important mediator of response to CBT...
  44. pmc Ethnic differences in substance abuse treatment retention, compliance, and outcome from two clinical trials
    Celeste O Milligan
    Psychiatry Department at Yale University School of Medicine, Clinical Research Unit, New Haven, Connecticut 06511, USA
    Psychiatr Serv 55:167-73. 2004
    ....
  45. pmc Primary outcomes in two randomized controlled trials of treatments for cannabis use disorders
    Erica N Peters
    Yale University School of Medicine, Department of Psychiatry, One Long Wharf Drive, Box 18, New Haven, CT 06511, USA
    Drug Alcohol Depend 118:408-16. 2011
    ....
  46. ncbi request reprint The URICA as a measure of motivation to change among treatment-seeking individuals with concurrent alcohol and cocaine problems
    Michael V Pantalon
    Department of Psychiatry Division of Substance Abuse, Yale University School of Medicine, CMHC SAC S209, 34 Park Street, New Haven, Connecticut 06519, USA
    Psychol Addict Behav 16:299-307. 2002
    ....
  47. pmc Neurocognitive indicators predict results of an informed-consent quiz among substance-dependent treatment seekers entering a randomized clinical trial
    Brian D Kiluk
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, Connecticut 06516, USA
    J Stud Alcohol Drugs 71:704-12. 2010
    ....
  48. pmc Coping strategy use following computerized cognitive-behavioral therapy for substance use disorders
    Dawn E Sugarman
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Psychol Addict Behav 24:689-95. 2010
    ....
  49. ncbi request reprint Contingency management to enhance naltrexone treatment of opioid dependence: a randomized clinical trial of reinforcement magnitude
    Kathleen M Carroll
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Exp Clin Psychopharmacol 10:54-63. 2002
    ..These findings suggest that targeted behavioral therapies can play a substantial role in broadening the utility of available pharmacotherapies...
  50. pmc Cost effectiveness of disulfiram: treating cocaine use in methadone-maintained patients
    Mireia Jofre-Bonet
    ICEH London School of Hygiene and Tropical Medicine, Keppel Street, Room 9 311, London WC1E 7HT, UK
    J Subst Abuse Treat 26:225-32. 2004
    ....
  51. pmc Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom?
    Nancy M Petry
    University of Connecticut Health Center, Farmington, CT, USA
    Addiction 99:349-60. 2004
    ..This study evaluated the efficacy of a low-cost, prize reinforcement contingency management (CM) intervention for reducing cocaine use...
  52. pmc Contingency Management to reduce substance use in individuals who are homeless with co-occurring psychiatric disorders
    Kathlene Tracy
    New York University School of Medicine, New York, NY 10032, USA
    Am J Drug Alcohol Abuse 33:253-8. 2007
    ..This pilot trial suggests that application of low-cost CM procedures is feasible within this novel setting and may decrease substance use...