Nancy A Moran

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Distinctive gut microbiota of honey bees assessed using deep sampling from individual worker bees
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    PLoS ONE 7:e36393. 2012
  2. doi request reprint Lateral transfer of genes from fungi underlies carotenoid production in aphids
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, 1041 East Lowell Street, University of Arizona, Tucson, AZ 85721, USA
    Science 328:624-7. 2010
  3. pmc Convergent evolution of metabolic roles in bacterial co-symbionts of insects
    John P McCutcheon
    Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 106:15394-9. 2009
  4. doi request reprint Frischella perrara gen. nov., sp. nov., a gammaproteobacterium isolated from the gut of the honeybee, Apis mellifera
    Philipp Engel
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
    Int J Syst Evol Microbiol 63:3646-51. 2013
  5. doi request reprint Evolutionary genetics of a defensive facultative symbiont of insects: exchange of toxin-encoding bacteriophage
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Biosciences West, Room 310, 1041 E Lowell Street, University of Arizona, Tucson, AZ 85721 0088, USA
    Mol Ecol 17:916-29. 2008
  6. pmc Evolution and diversity of facultative symbionts from the aphid subfamily Lachninae
    Gaelen R Burke
    Department of Ecology and Evolutionary Biology, University of Arizona, 1041 East Lowell Street, Tucson, Arizona 85721 0088, USA
    Appl Environ Microbiol 75:5328-35. 2009
  7. ncbi request reprint The evolutionary history of quorum-sensing systems in bacteria
    Emmanuelle Lerat
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ, USA
    Mol Biol Evol 21:903-13. 2004
  8. pmc Evolutionary origins of genomic repertoires in bacteria
    Emmanuelle Lerat
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, USA
    PLoS Biol 3:e130. 2005
  9. pmc Diverse phage-encoded toxins in a protective insect endosymbiont
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721 0088, USA
    Appl Environ Microbiol 74:6782-91. 2008
  10. pmc Chromosome stability and gene loss in cockroach endosymbionts
    Zakee L Sabree
    Center for Insect Science, University of Arizona, Tucson, Arizona 85721, USA
    Appl Environ Microbiol 76:4076-9. 2010

Detail Information

Publications72

  1. pmc Distinctive gut microbiota of honey bees assessed using deep sampling from individual worker bees
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    PLoS ONE 7:e36393. 2012
    ..Strains showed some differentiation between localities, especially for the Snodgrassella phylotype...
  2. doi request reprint Lateral transfer of genes from fungi underlies carotenoid production in aphids
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, 1041 East Lowell Street, University of Arizona, Tucson, AZ 85721, USA
    Science 328:624-7. 2010
    ..A mutation causing an amino acid replacement in this desaturase results in loss of torulene and of red body color. Thus, aphids are animals that make their own carotenoids...
  3. pmc Convergent evolution of metabolic roles in bacterial co-symbionts of insects
    John P McCutcheon
    Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 106:15394-9. 2009
    ....
  4. doi request reprint Frischella perrara gen. nov., sp. nov., a gammaproteobacterium isolated from the gut of the honeybee, Apis mellifera
    Philipp Engel
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
    Int J Syst Evol Microbiol 63:3646-51. 2013
    ..nov., sp. nov. The type strain of Frischella perrara is PEB0191(T) ( = NCIMB 14821(T) = ATCC BAA-2450(T)). ..
  5. doi request reprint Evolutionary genetics of a defensive facultative symbiont of insects: exchange of toxin-encoding bacteriophage
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Biosciences West, Room 310, 1041 E Lowell Street, University of Arizona, Tucson, AZ 85721 0088, USA
    Mol Ecol 17:916-29. 2008
    ..pisum, one subclade of H. defensa appears to be universal within a subclade of the aphid genus Uroleucon, suggesting a transition from facultative, horizontal transmission to strictly vertical inheritance...
  6. pmc Evolution and diversity of facultative symbionts from the aphid subfamily Lachninae
    Gaelen R Burke
    Department of Ecology and Evolutionary Biology, University of Arizona, 1041 East Lowell Street, Tucson, Arizona 85721 0088, USA
    Appl Environ Microbiol 75:5328-35. 2009
    ..Serratia symbiotica" with Cinara subgenus Cinara species and weigh against an obligate nutritional role. Finally, we show that species belonging to the subfamily Lachninae have a high incidence of facultative symbiont infection...
  7. ncbi request reprint The evolutionary history of quorum-sensing systems in bacteria
    Emmanuelle Lerat
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ, USA
    Mol Biol Evol 21:903-13. 2004
    ..Gene phylogenies for the main LuxI/R family in Pseudomonas species imply a complex history of lateral transfer, ancestral duplication, and gene loss within the genus...
  8. pmc Evolutionary origins of genomic repertoires in bacteria
    Emmanuelle Lerat
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, USA
    PLoS Biol 3:e130. 2005
    ..Although our analyses are limited to the gamma-Proteobacteria, these results resolve a long-standing paradox-i.e., the ability to make robust phylogenetic inferences in light of substantial LGT...
  9. pmc Diverse phage-encoded toxins in a protective insect endosymbiont
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721 0088, USA
    Appl Environ Microbiol 74:6782-91. 2008
    ..Thus, phage may act as a conduit for ongoing gene exchange among heritable endosymbionts...
  10. pmc Chromosome stability and gene loss in cockroach endosymbionts
    Zakee L Sabree
    Center for Insect Science, University of Arizona, Tucson, Arizona 85721, USA
    Appl Environ Microbiol 76:4076-9. 2010
    ..We speculate that distant homologs may replace the functions of some eliminated genes through broadened substrate specificity...
  11. doi request reprint The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Science 323:379-82. 2009
    ..Although purifying selection eliminates many mutations, some persist, resulting in ongoing loss of genes and DNA from this already tiny genome. Our results provide a general model for the stepwise process leading to genome reduction...
  12. doi request reprint Multiple introductions of the Spiroplasma bacterial endosymbiont into Drosophila
    Tamara S Haselkorn
    Department of Ecology and Evolutionary Biology Biosciences, University of Arizona, Tucson, 85721 0088, USA
    Mol Ecol 18:1294-305. 2009
    ..Patterns of variation in Drosophila mitochondrial haplotypes in Spiroplasma-infected and uninfected flies imply imperfect vertical transmission in host populations and possible horizontal transmission...
  13. pmc Regulation of transcription in a reduced bacterial genome: nutrient-provisioning genes of the obligate symbiont Buchnera aphidicola
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    J Bacteriol 187:4229-37. 2005
    ..The irreversible losses of transcriptional regulators constrain ability to alter gene expression in the context of environmental fluctuations affecting the symbiotic partners...
  14. pmc The consequences of genetic drift for bacterial genome complexity
    Chih Horng Kuo
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Genome Res 19:1450-4. 2009
    ..This ratio, which reflects the action of purifying selection across the entire genome, shows a strong inverse relationship with genome size, indicating that drift promotes genome reduction in bacteria...
  15. pmc From gene trees to organismal phylogeny in prokaryotes: the case of the gamma-Proteobacteria
    Emmanuelle Lerat
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, USA
    PLoS Biol 1:E19. 2003
    ....
  16. doi request reprint Evolutionary replacement of obligate symbionts in an ancient and diverse insect lineage
    Ryuichi Koga
    Department of Ecology and Evolutionary Biology and Microbial Diversity Institute, Yale University, New Haven, CT 06511, USA
    Environ Microbiol 15:2073-81. 2013
    ..Symbiont replacement may offer a route for hosts to escape dependence on an ancient, degraded and potentially inefficient symbiont. ..
  17. doi request reprint The nutrient supplying capabilities of Uzinura, an endosymbiont of armoured scale insects
    Zakee L Sabree
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA
    Environ Microbiol 15:1988-99. 2013
    ..Despite this extreme genome reduction, the absence of a known obligate partner bacterial symbiont suggests that Uzinura alone can supply sufficient nutrients to its host. ..
  18. pmc Genome reduction and co-evolution between the primary and secondary bacterial symbionts of psyllids
    Daniel B Sloan
    Department of Ecology and Evolutionary Biology, Yale University, USA
    Mol Biol Evol 29:3781-92. 2012
    ....
  19. doi request reprint A simple and distinctive microbiota associated with honey bees and bumble bees
    Vincent G Martinson
    Center for Insect Science, University of Arizona, 1007 East Lowell Street, Tucson, AZ 85721 0088, USA
    Mol Ecol 20:619-28. 2011
    ..Phylogenetic analyses provide a more refined taxonomic placement of the A. mellifera symbionts...
  20. pmc Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Arizona Genomics Institute, University of Arizona, Tucson, AZ 85721 USA
    Proc Natl Acad Sci U S A 106:9063-8. 2009
    ..The genome is also littered with mobile DNA, including phage-derived genes, plasmids, and insertion-sequence elements, highlighting its dynamic nature and the continued role horizontal gene transfer plays in shaping it...
  21. doi request reprint Genomics and evolution of heritable bacterial symbionts
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Annu Rev Genet 42:165-90. 2008
    ..In addition, insect symbionts provide some of the extremes of cellular genomes, including the smallest and the fastest evolving, raising new questions about the limits of evolution of life...
  22. pmc Symbiosis as an adaptive process and source of phenotypic complexity
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 104:8627-33. 2007
    ..Multiple symbionts often coexist in the same host, resulting in coadaptation among several phylogenetically distant genomes...
  23. pmc Extracting single genomes from heterogenous DNA samples: a test case with Carsonella ruddii, the bacterial symbiont of psyllids (Insecta)
    Colin Dale
    Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, Arizona 85721, USA
    J Insect Sci 5:3. 2005
    ..The resulting libraries were highly enriched in bacterial sequences. Through the use of alternate enzymes and partial digests, this technique can be adapted to yield virtually pure DNA libraries for individual bacterial species...
  24. pmc Population dynamics of defensive symbionts in aphids
    Kerry M Oliver
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Biol Sci 275:293-9. 2008
    ..The declining frequencies of Hamiltonella-infected aphids in population cages in the absence of parasitism indicate a probable cost to infection and may explain why Hamiltonella remains at intermediate frequencies in natural populations...
  25. ncbi request reprint Functional genomics of Buchnera and the ecology of aphid hosts
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Mol Ecol 15:1251-61. 2006
    ..Although information for other insect symbioses is relatively limited, studies on symbionts of carpenter ants and tsetse flies indicate many similarities to Buchnera...
  26. pmc A dual-genome microarray for the pea aphid, Acyrthosiphon pisum, and its obligate bacterial symbiont, Buchnera aphidicola
    Alex C C Wilson
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    BMC Genomics 7:50. 2006
    ..Development of this dual-genome array represents a first attempt to characterize gene expression in this emerging model system...
  27. doi request reprint Cultivation and characterization of the gut symbionts of honey bees and bumble bees: description of Snodgrassella alvi gen. nov., sp. nov., a member of the family Neisseriaceae of the Betaproteobacteria, and Gilliamella apicola gen. nov., sp. nov., a memb
    Waldan K Kwong
    Department of Ecology and Evolutionary Biology, Yale University, 165 Prospect Street, New Haven, CT 06511, USA
    Int J Syst Evol Microbiol 63:2008-18. 2013
    ..hercynius in a new family and order, Orbaceae fam. nov. and Orbales ord. nov...
  28. pmc Nitrogen recycling and nutritional provisioning by Blattabacterium, the cockroach endosymbiont
    Zakee L Sabree
    Department of Ecology and Evolutionary Biology, University of Arizona, Center for Insect Science, Tucson, AZ 85721 0088, USA
    Proc Natl Acad Sci U S A 106:19521-6. 2009
    ....
  29. pmc Costs and benefits of a superinfection of facultative symbionts in aphids
    Kerry M Oliver
    Department of Entomology, University of Arizona, 410 Forbes Building, Tucson, AZ 85721, USA
    Proc Biol Sci 273:1273-80. 2006
    ..Our results indicate that in addition to host-symbiont interactions, interactions among the symbionts themselves probably play a critical role in determining the distributions of symbionts in natural populations...
  30. pmc The players in a mutualistic symbiosis: insects, bacteria, viruses, and virulence genes
    Nancy A Moran
    Departments of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 87521, USA
    Proc Natl Acad Sci U S A 102:16919-26. 2005
    ..defensa life cycle. We propose that, in these mutualistic symbionts, phage-borne toxin genes provide defense to the aphid host and are a basis for the observed protection against eukaryotic parasites...
  31. pmc Dynamics of a recurrent Buchnera mutation that affects thermal tolerance of pea aphid hosts
    Gaelen R Burke
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Genetics 186:367-72. 2010
    ..This single base polymorphism in Buchnera has the potential to allow aphid populations to adapt quickly to prevailing conditions...
  32. pmc Aphid thermal tolerance is governed by a point mutation in bacterial symbionts
    Helen E Dunbar
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America
    PLoS Biol 5:e96. 2007
    ..Other cases in which symbiont microevolution has a major effect on host ecological tolerance are likely to be widespread because of the high mutation rates of symbiotic bacteria and their crucial roles in host metabolism and development...
  33. pmc Origin and examination of a leafhopper facultative endosymbiont
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA
    Curr Microbiol 62:1565-72. 2011
    ..However, the slightly reduced genome size, abundance of mobile DNA, fastidious growth in culture, and efficient vertical transmission suggest that symbiosis with E. variegatus has had a significant impact on genome evolution in BEV...
  34. pmc Functional and evolutionary analysis of the genome of an obligate fungal symbiont
    Kevin J Vogel
    Department of Ecology and Evolutionary Biology, University of Arizona, USA
    Genome Biol Evol 5:891-904. 2013
    ..The patterns observed in the YLS genome suggest that its symbiotic lifestyle is permissive to intron proliferation and accelerated sequence evolution, though other factors appear to limit its overall genome expansion...
  35. pmc Functional and evolutionary insights into the simple yet specific gut microbiota of the honey bee from metagenomic analysis
    Philipp Engel
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA
    Gut Microbes 4:60-5. 2013
    ..In this addendum, we summarize and discuss our major findings and provide a detailed perspective on future research...
  36. pmc Functional diversity within the simple gut microbiota of the honey bee
    Philipp Engel
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 109:11002-7. 2012
    ....
  37. pmc Aphid genome expression reveals host-symbiont cooperation in the production of amino acids
    Allison K Hansen
    Department of Ecology and Evolutionary Biology, Yale University, West Haven, CT 06516 7388, USA
    Proc Natl Acad Sci U S A 108:2849-54. 2011
    ..Furthermore, the GOGAT cycle may be a key source of nitrogen fueling the integrated amino acid metabolism of the aphid-Buchnera partnership...
  38. ncbi request reprint Phylogenetics and the cohesion of bacterial genomes
    Vincent Daubin
    Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ, 85721, USA
    Science 301:829-32. 2003
    ..Although comparisons of complete gene inventories indicate appreciable gain and loss of genes, orthologs available for phylogenetic reconstruction are consistent with a single tree...
  39. pmc Sequence conservation and functional constraint on intergenic spacers in reduced genomes of the obligate symbiont Buchnera
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS Genet 7:e1002252. 2011
    ..Although pseudogene formation, and thus IGS formation, are ongoing processes in these genomes, a large proportion of intergenic spacers contain functional sequences...
  40. ncbi request reprint Low and homogeneous copy number of plasmid-borne symbiont genes affecting host nutrition in Buchnera aphidicola of the aphid Uroleucon ambrosiae
    Gordon R Plague
    Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Mol Ecol 12:1095-100. 2003
    ..Consequently, the plasmid location of trpEG combined with Buchnera's chromosomal polyploidy may functionally limit, rather than increase, tryptophan production within Uroleucon ambrosiae...
  41. pmc Symbiosis and insect diversification: an ancient symbiont of sap-feeding insects from the bacterial phylum Bacteroidetes
    Nancy A Moran
    Biological Sciences West 310, Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Appl Environ Microbiol 71:8802-10. 2005
    ..Candidatus Sulcia muelleri" is proposed as the name of the new symbiont...
  42. pmc Massive genomic decay in Serratia symbiotica, a recently evolved symbiont of aphids
    Gaelen R Burke
    Department of Ecology and Evolutionary Biology, The University of Arizona, USA
    Genome Biol Evol 3:195-208. 2011
    ..Analysis of mutational patterns showed that deletions are more common in neutral DNA. The S. symbiotica genome provides a rare opportunity to study genome evolution in a recently derived heritable symbiont...
  43. ncbi request reprint Comment on "The origins of genome complexity"
    Vincent Daubin
    Department of Biochemistry and Molecular Biophysics, University of Arizona Tuscon, AZ 85721, USA
    Science 306:978; author reply 978. 2004
  44. pmc Evolutionary relationships of three new species of Enterobacteriaceae living as symbionts of aphids and other insects
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, Biological Sciences West 310, University of Arizona, Tucson, Arizona 85721, USA
    Appl Environ Microbiol 71:3302-10. 2005
    ..The other two symbionts, here designated "Candidatus Hamiltonella defensa" and "Candidatus Regiella insecticola," are sister groups to one another and together show a relationship to species of Photorhabdus...
  45. pmc Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont
    John P McCutcheon
    Center for Insect Science, University of Arizona, Tucson, AZ, USA
    PLoS Genet 5:e1000565. 2009
    ..Although it is not clear why this tiny genome lacks the low GC content typical of other small bacterial genomes, these observations support a role of genome reduction rather than base composition as a driver of codon reassignment...
  46. doi request reprint The gut microbiota of insects - diversity in structure and function
    Philipp Engel
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
    FEMS Microbiol Rev 37:699-735. 2013
    ..The extent of these roles is still unclear and awaits further studies. ..
  47. pmc The evolution of genomic instability in the obligate endosymbionts of whiteflies
    Daniel B Sloan
    Department of Ecology and Evolutionary Biology, Yale University, USA
    Genome Biol Evol 5:783-93. 2013
    ....
  48. pmc Endosymbiotic bacteria as a source of carotenoids in whiteflies
    Daniel B Sloan
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA
    Biol Lett 8:986-9. 2012
    ..Therefore, related lineages of sap-feeding insects appear to have convergently acquired the same functional trait by distinct evolutionary mechanisms-bacterial endosymbiosis versus fungal lateral gene transfer...
  49. pmc Independent studies using deep sequencing resolve the same set of core bacterial species dominating gut communities of honey bees
    Zakee L Sabree
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    PLoS ONE 7:e41250. 2012
    ..The roles of these bacteria within bees, or the implications of the strain variation, are not yet clear...
  50. pmc Genome sequence of Blattabacterium sp. strain BGIGA, endosymbiont of the Blaberus giganteus cockroach
    Charlie Y Huang
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    J Bacteriol 194:4450-1. 2012
    ..We report the complete genome sequence of the Blattabacterium sp. associated with the giant roach Blaberus giganteus...
  51. doi request reprint Diversification of genes for carotenoid biosynthesis in aphids following an ancient transfer from a fungus
    Eva Novakova
    Department of Ecology and Evolutionary Biology, Yale University, USA
    Mol Biol Evol 29:313-23. 2012
    ....
  52. pmc Establishment of characteristic gut bacteria during development of the honeybee worker
    Vincent G Martinson
    Center for Insect Science, University of Arizona, Tucson, Arizona, USAa Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, USA
    Appl Environ Microbiol 78:2830-40. 2012
    ..mellifera ontogeny. We propose the names "Candidatus Snodgrassella alvi" and "Candidatus Gilliamella apicola" for the Beta and Gamma-1 phylotypes, respectively...
  53. pmc Genomic basis of endosymbiont-conferred protection against an insect parasitoid
    Allison K Hansen
    Department of Ecology and Evolutionary Biology, Yale University, West Haven, Connecticut 06516 7388, USA
    Genome Res 22:106-14. 2012
    ..Mechanisms through which these factors may target parasitoids are discussed...
  54. pmc A genomic perspective on nutrient provisioning by bacterial symbionts of insects
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:14543-8. 2003
    ....
  55. ncbi request reprint Genomic changes following host restriction in bacteria
    Nancy A Moran
    Department of Ecology and Evolutionary Biology and Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Curr Opin Genet Dev 14:627-33. 2004
    ..Considerable variation also exists, however, in part reflecting unstudied aspects of the population structure and ecology of host-restricted bacterial lineages...
  56. pmc Dynamics of genome evolution in facultative symbionts of aphids
    Patrick H Degnan
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Environ Microbiol 12:2060-9. 2010
    ..The divergence in gene sets and in genome architecture implies a history of rampant recombination and gene inactivation and the ongoing integration of mobile DNA (insertion sequence elements, prophage and plasmids)...
  57. pmc Parallel genomic evolution and metabolic interdependence in an ancient symbiosis
    John P McCutcheon
    Center for Insect Science and Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721 0088, USA
    Proc Natl Acad Sci U S A 104:19392-7. 2007
    ..Analysis of the coding capacities of Sulcia and Baumannia reveals striking complementarity in metabolic capabilities...
  58. pmc Altered tRNA characteristics and 3' maturation in bacterial symbionts with reduced genomes
    Allison K Hansen
    Department of Ecology and Evolutionary Biology, West Campus, Yale University, PO Box 27388 West Haven, CT 06516 7388, USA
    Nucleic Acids Res 40:7870-84. 2012
    ..Overall, our data suggest that endosymbiont genome evolution alters tRNA characteristics that are known to influence translational efficiency in their free-living relative...
  59. pmc Genome shrinkage and loss of nutrient-providing potential in the obligate symbiont of the primitive termite Mastotermes darwiniensis
    Zakee L Sabree
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    Appl Environ Microbiol 78:204-10. 2012
    ....
  60. pmc Variation in resistance to parasitism in aphids is due to symbionts not host genotype
    Kerry M Oliver
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 102:12795-800. 2005
    ..Thus, acquisition of a heritable symbiont appears to be a major mode of adaptation to natural enemy pressure in these insects...
  61. pmc Variable incidence of Spiroplasma infections in natural populations of Drosophila species
    Thomas Watts
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America
    PLoS ONE 4:e5703. 2009
    ..These findings suggest that Spiroplasma has other effects on hosts that allow it to persist, and that environmental or host variation affects transmission or persistence leading to differences among populations in infection frequencies...
  62. pmc Costs and benefits of symbiont infection in aphids: variation among symbionts and across temperatures
    Jacob A Russell
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ, USA
    Proc Biol Sci 273:603-10. 2006
    ..insecticola under these same conditions. These findings reveal a role for heritable symbionts in the adaptation of aphids to their abiotic environments and add to an expanding body of knowledge on the adaptive significance of symbiosis...
  63. pmc Sources of variation in dietary requirements in an obligate nutritional symbiosis
    Kevin J Vogel
    Department of Ecology and Evolutionary Biology, The University of Arizona, Tucson, AZ 85721, USA
    Proc Biol Sci 278:115-21. 2011
    ..Our results indicate that variation among pea aphids in dependence on dietary amino acids can result from Buchnera mutation as well as variation in the host genotype...
  64. pmc Sexual acquisition of beneficial symbionts in aphids
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 103:12803-6. 2006
    ..Because such transfer can generate coinfections, thereby creating opportunities for symbiont competition and recombination, paternal inheritance has major consequences for expectations regarding symbiont evolution...
  65. ncbi request reprint Consequences of reductive evolution for gene expression in an obligate endosymbiont
    Jennifer L Wilcox
    Department of Ecology and Evolutionary Biology, University of Arizona, BioSciences West Rm 310, Tucson 85721, USA
    Mol Microbiol 48:1491-500. 2003
    ..aphidicola. Our demonstration of a diminished stress response validates reports of temperature sensitivity in B. aphidicola and suggests that this reduced bacterial genome exhibits transcriptional inflexibility...
  66. ncbi request reprint Tracing the evolution of gene loss in obligate bacterial symbionts
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
    Curr Opin Microbiol 6:512-8. 2003
    ..This pattern appears to be characteristic of symbiont evolution...
  67. pmc Heritable endosymbionts of Drosophila
    Mariana Mateos
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Genetics 174:363-76. 2006
    ..Several new strains of Wolbachia and Spiroplasma were discovered, including ones divergent from any reported to date. The phylogenetic distribution of Wolbachia and Spiroplasma in Drosophila is discussed...
  68. ncbi request reprint Symbiosis
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA
    Curr Biol 16:R866-71. 2006
  69. pmc Functional convergence in reduced genomes of bacterial symbionts spanning 200 My of evolution
    John P McCutcheon
    Center for Insect Science, University of Arizona, Arizona, USA
    Genome Biol Evol 2:708-18. 2010
    ....
  70. pmc Facultative bacterial symbionts in aphids confer resistance to parasitic wasps
    Kerry M Oliver
    Department of Entomology, University of Arizona, Tucson, AZ 85721, USA
    Proc Natl Acad Sci U S A 100:1803-7. 2003
    ..This strong interaction between a symbiotic bacterium and a host natural enemy provides a mechanism for the persistence and spread of symbiotic bacteria...
  71. ncbi request reprint Intracellular symbionts of sharpshooters (Insecta: Hemiptera: Cicadellinae) form a distinct clade with a small genome
    Nancy A Moran
    Department of Ecology and Evolutionary Biology, Biological Sciences West 310, University of Arizona, Tucson 85721, USA
    Environ Microbiol 5:116-26. 2003
    ..A new genus and species name, 'Candidatus Baumannia cicadellinicola' (sp. nov.) is proposed for this newly characterized clade of symbiotic bacteria...
  72. pmc Type III secretion systems and the evolution of mutualistic endosymbiosis
    Colin Dale
    Department of Ecology and Evolutionary Biology, Center for Insect Science, and Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ 85721
    Proc Natl Acad Sci U S A 99:12397-402. 2002
    ..The function of inv/spa genes in maintaining symbiosis is demonstrated by the up-regulation of their expression under both in vivo and in vitro conditions that coincide with host cell invasion...