Michelle Y Monette

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Regulatory activation is accompanied by movement in the C terminus of the Na-K-Cl cotransporter (NKCC1)
    Michelle Y Monette
    Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut 06520, USA
    J Biol Chem 287:2210-20. 2012
  2. ncbi request reprint Impacts of short-term acid and aluminum exposure on Atlantic salmon (Salmo salar) physiology: a direct comparison of parr and smolts
    Michelle Y Monette
    Organismic and Evolutionary Biology, University of Massachusetts, 611 North Pleasant Street, Amherst, MA 01003, USA
    Aquat Toxicol 86:216-26. 2008
  3. doi request reprint Effects of short-term acid and aluminum exposure on the parr-smolt transformation in Atlantic salmon (Salmo salar): disruption of seawater tolerance and endocrine status
    Michelle Y Monette
    Graduate Program in Organismic and Evolutionary Biology, University of Massachusetts, 611 N Pleasant Street, Amherst, MA 01003, USA
    Gen Comp Endocrinol 158:122-30. 2008
  4. pmc Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function
    Michelle Y Monette
    Dept of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Yale Univ School of Medicine, New Haven, CT 06520, USA
    Am J Physiol Renal Physiol 300:F840-7. 2011
  5. ncbi request reprint Physiological, molecular, and cellular mechanisms of impaired seawater tolerance following exposure of Atlantic salmon, Salmo salar, smolts to acid and aluminum
    Michelle Y Monette
    Organismic and Evolutionary Biology Program, University of Massachusetts, Amherst, MA 01003
    Aquat Toxicol 99:17-32. 2010
  6. pmc Molecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12
    Michelle Y Monette
    From the Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut 06520
    J Biol Chem 289:7569-79. 2014
  7. pmc Phosphorylation state of the Na+-K+-Cl- cotransporter (NKCC1) in the gills of Atlantic killifish (Fundulus heteroclitus) during acclimation to water of varying salinity
    Andreas W Flemmer
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, PO Box 208026, New Haven, CT 06520, USA
    J Exp Biol 213:1558-66. 2010
  8. pmc Functional expression of human NKCC1 from a synthetic cassette-based cDNA: introduction of extracellular epitope tags and removal of cysteines
    Suma Somasekharan
    Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 8:e82060. 2013

Collaborators

Detail Information

Publications8

  1. pmc Regulatory activation is accompanied by movement in the C terminus of the Na-K-Cl cotransporter (NKCC1)
    Michelle Y Monette
    Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut 06520, USA
    J Biol Chem 287:2210-20. 2012
    ..It is anticipated that when combined with structural information, our findings will provide a model for understanding the conformational changes that bring about NKCC1 regulation...
  2. ncbi request reprint Impacts of short-term acid and aluminum exposure on Atlantic salmon (Salmo salar) physiology: a direct comparison of parr and smolts
    Michelle Y Monette
    Organismic and Evolutionary Biology, University of Massachusetts, 611 North Pleasant Street, Amherst, MA 01003, USA
    Aquat Toxicol 86:216-26. 2008
    ..Instead, increased sensitivity of smolts is likely a result of both the acquisition of seawater tolerance while still in freshwater and heightened stress responsiveness in preparation for seawater entry and residence...
  3. doi request reprint Effects of short-term acid and aluminum exposure on the parr-smolt transformation in Atlantic salmon (Salmo salar): disruption of seawater tolerance and endocrine status
    Michelle Y Monette
    Graduate Program in Organismic and Evolutionary Biology, University of Massachusetts, 611 N Pleasant Street, Amherst, MA 01003, USA
    Gen Comp Endocrinol 158:122-30. 2008
    ..Loss of SW tolerance during short-term acid/Al exposure likely results from reductions in gill NKA and NKCC, possibly mediated by decreases in plasma IGF-I and T(3)...
  4. pmc Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function
    Michelle Y Monette
    Dept of Cellular and Molecular Physiology, Howard Hughes Medical Institute, Yale Univ School of Medicine, New Haven, CT 06520, USA
    Am J Physiol Renal Physiol 300:F840-7. 2011
    ..to identify functionally important residues by sequence conservation. Such mutations in hNKCC2A are likely to reduce renal salt reabsorption, providing a mechanism for lower blood pressure...
  5. ncbi request reprint Physiological, molecular, and cellular mechanisms of impaired seawater tolerance following exposure of Atlantic salmon, Salmo salar, smolts to acid and aluminum
    Michelle Y Monette
    Organismic and Evolutionary Biology Program, University of Massachusetts, Amherst, MA 01003
    Aquat Toxicol 99:17-32. 2010
    ..When smolts are exposed to acid and low levels of Al, loss of seawater tolerance appears to be independent of these mechanisms and may result instead from a shift in the phenotype of MRCs present in the gill epithelium...
  6. pmc Molecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12
    Michelle Y Monette
    From the Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut 06520
    J Biol Chem 289:7569-79. 2014
    ....
  7. pmc Phosphorylation state of the Na+-K+-Cl- cotransporter (NKCC1) in the gills of Atlantic killifish (Fundulus heteroclitus) during acclimation to water of varying salinity
    Andreas W Flemmer
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, PO Box 208026, New Haven, CT 06520, USA
    J Exp Biol 213:1558-66. 2010
    ..7-fold greater in SW-acclimated killifish relative to FW fish. Overall, these results demonstrate an important role of NKCC1 phosphorylation in the gill of Atlantic killifish during acute salinity acclimation...
  8. pmc Functional expression of human NKCC1 from a synthetic cassette-based cDNA: introduction of extracellular epitope tags and removal of cysteines
    Suma Somasekharan
    Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 8:e82060. 2013
    ..Together these advances are expected to greatly assist future studies of NKCC1. ..