Y S Mineur

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Functional implications of decreases in neurogenesis following chronic mild stress in mice
    Y S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Neuroscience 150:251-9. 2007
  2. ncbi request reprint Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Behav Brain Res 175:43-50. 2006
  3. pmc Genetic mouse models of Alzheimer's disease
    Yann S Mineur
    Yale School of Medicine, Department of Psychiatry, 34 Park Street, 3rd Floor Research, New Haven, CT 06508, USA
    Neural Plast 12:299-310. 2005
  4. pmc Genetic dissection of learning and memory in mice
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School Worcester, MA 01604, USA
    Neural Plast 11:217-40. 2004
  5. doi request reprint Behavioral effects of ventilated micro-environment housing in three inbred mouse strains
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, 303 Belmont Street, Worcester, MA 01604, USA
    Physiol Behav 97:334-40. 2009
  6. pmc Blockade of protein phosphatase 2B activity in the amygdala increases anxiety- and depression-like behaviors in mice
    Amine Bahi
    Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 66:1139-46. 2009
  7. pmc Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference
    Darlene H Brunzell
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 34:1993-2001. 2009
  8. pmc Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors
    Patricia Vieyra-Reyes
    Yale University, Department of Psychiatry, 34 Park Street, New Haven, CT 06508, USA
    Neurosci Lett 434:18-22. 2008
  9. ncbi request reprint Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester 01604, USA
    Hippocampus 12:39-46. 2002
  10. pmc It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood
    Marina R Picciotto
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA
    Prog Neurobiol 84:329-42. 2008

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Functional implications of decreases in neurogenesis following chronic mild stress in mice
    Y S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Neuroscience 150:251-9. 2007
    ..However, the specific results were strongly dependent on strain and sex so that there does not appear to be a direct causative relationship between the deficits in neurogenesis and behavior...
  2. ncbi request reprint Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Behav Brain Res 175:43-50. 2006
    ..The goals of these experiments are to obtain a clearer behavioral profile of genetically/phenotypically distant mouse strains after UCMS treatment and to evaluate the limitations and strengths of the UCMS model in mice...
  3. pmc Genetic mouse models of Alzheimer's disease
    Yann S Mineur
    Yale School of Medicine, Department of Psychiatry, 34 Park Street, 3rd Floor Research, New Haven, CT 06508, USA
    Neural Plast 12:299-310. 2005
    ..Rather, we aim to steer the Alzheimer's novice through the recent mouse literature on AD. Special attention will be paid to genetic models that have been tested behaviorally...
  4. pmc Genetic dissection of learning and memory in mice
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School Worcester, MA 01604, USA
    Neural Plast 11:217-40. 2004
    ..All sections are illustrated with examples from the learning and memory field, including a table summarizing the latest information about genes that have been shown to have effects on learning and memory...
  5. doi request reprint Behavioral effects of ventilated micro-environment housing in three inbred mouse strains
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, 303 Belmont Street, Worcester, MA 01604, USA
    Physiol Behav 97:334-40. 2009
    ..In addition, behavioral baseline data will have to be re-established once the switch has been completed...
  6. pmc Blockade of protein phosphatase 2B activity in the amygdala increases anxiety- and depression-like behaviors in mice
    Amine Bahi
    Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 66:1139-46. 2009
    ..It is therefore important to determine whether chronic blockade of calcineurin might contribute to symptoms of anxiety and depression in these patients...
  7. pmc Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference
    Darlene H Brunzell
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 34:1993-2001. 2009
    ..Taken together, these studies identify the NAc shell as a brain region where CREB activity is essential for nicotine CPP...
  8. pmc Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors
    Patricia Vieyra-Reyes
    Yale University, Department of Psychiatry, 34 Park Street, New Haven, CT 06508, USA
    Neurosci Lett 434:18-22. 2008
    ..In addition, alterations in CREB and GluR1 levels are not sufficient to explain preference for nicotine in a 2-bottle choice paradigm...
  9. ncbi request reprint Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester 01604, USA
    Hippocampus 12:39-46. 2002
    ..These data suggest the involvement of FMRP protein in the development of spatial learning and the sprouting of IIPMF terminal fields...
  10. pmc It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood
    Marina R Picciotto
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA
    Prog Neurobiol 84:329-42. 2008
    ..We conclude that there are effects of nAChR activation and desensitization on drug reinforcement and affective behavior, and that both processes are important in the behavioral consequences of nicotine in tobacco smoking...
  11. pmc Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice
    Yann S Mineur
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, 3rd Floor Research, New Haven, CT 06508, USA
    Neuropharmacology 52:1256-62. 2007
    ..These studies also suggest that both antagonists and partial agonists of alpha4/beta2*nAChRs would be interesting targets for the development of novel antidepressant drugs...
  12. pmc Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
    Yann S Mineur
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, 3rd Floor Research, New Haven, CT 06508, USA
    Biochem Pharmacol 75:323-33. 2008
    ....
  13. ncbi request reprint Antidepressant-like effects of ceftriaxone in male C57BL/6J mice
    Yann S Mineur
    Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 61:250-2. 2007
    ..Recent evidence that beta-lactam antibiotic agents stimulate uptake of glutamate suggests that this class of compounds might possess antidepressant-like activity...
  14. ncbi request reprint Agonistic behavior and unpredictable chronic mild stress in mice
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, Worcester, Massachussetts 01606, USA
    Behav Genet 33:513-9. 2003
    ..Furthermore, UCMS increased aggression both in a resident-intruder test and between cage-mates. UCMS is therefore a valuable model of the problematic aggressive behavior seen in depressive patients...
  15. pmc Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning
    Y S Mineur
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06515, USA
    Genes Brain Behav 8:257-66. 2009
    ..This suggests that partial activation of high-affinity nAChRs in VTA might block the rewarding effects of nicotine, providing a potential mechanism for the ability of nicotinic partial agonists to aid in smoking cessation...
  16. pmc Cytisine-based nicotinic partial agonists as novel antidepressant compounds
    Yann S Mineur
    Department of Psychiatry, Yale School of Medicine, New Haven, CT 06508, USA
    J Pharmacol Exp Ther 329:377-86. 2009
    ..These results suggest that novel nicotinic partial agonists may provide new possibilities for development of drugs to treat mood disorders...
  17. pmc The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration
    Jeremie Lavaur
    Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut, USA
    J Neurochem 111:1129-37. 2009
    ..These data indicate that adducin phosphorylation is a signaling event regulated by cocaine administration and further suggest that adducin may be involved in remodeling of the neuronal cytoskeleton in response to cocaine administration...
  18. ncbi request reprint Social behavior deficits in the Fmr1 mutant mouse
    Yann S Mineur
    Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, MA, USA
    Behav Brain Res 168:172-5. 2006
    ..KO animals showed strongly reduced levels of social interaction, which were about similar as those of habituated controls. This social behavior deficit suggests that Fmr1 KO mice could possibly be used as models for autistic behaviors...
  19. pmc Antidepressant-like effects of nicotine and transcranial magnetic stimulation in the olfactory bulbectomy rat model of depression
    Patricia Vieyra-Reyes
    Depto de Neurociencias Instituto de Fisiología Celular, Universidad Nacional Autonoma de Mexico, Circuito Interior, Ciudad Universitaria, CP 04510 Mexico, D F, Mexico
    Brain Res Bull 77:13-8. 2008
    ..In conclusion, our results support the idea that there are possible innate differences for depression susceptibility and that nicotine and TMS may be useful in the treatment of this syndrome...
  20. ncbi request reprint Behavioral and neuroanatomical characterization of FVB/N inbred mice
    Yann S Mineur
    Genetique, Neurogenetique et Comportement, FRE2134 CNRS, Institut de Transgénose, Orleans, France
    Brain Res Bull 57:41-7. 2002
    ..It is recommended that transgenic experiments employing this strain use F1 crosses between FVB/N and C57BL/6J as much as possible for behavioral experiments intended to evaluate spatial learning...