Haiqun Lin

..We argue that such a joint analysis with multiple longitudinal variables is advantageous to one with only a single longitudinal variable in revealing interplay among multiple longitudinal variables and the time-to-event...

..We decomposed the total effect of coexisting diseases on a timed occurrence of an adverse outcome into additive effects from individual diseases...

..The performance of the estimation procedure is assessed by simulation studies...

..Our model suggests the presence of four latent classes linking subject visit patterns to homeless outcomes...

..To examine changes in social support during early recovery after acute myocardial infarction (AMI) and determine whether these changes influence outcomes within the first year...

..However, before RRS measures of dermal carotenoids can be used as a biomarker, data on intra- and intersubject variability and validity are needed...

..TD with ADHD is associated with higher psychosocial stress and more externalizing behaviors. Further research is needed into the underlying relationships between these closely associated conditions...

..Studies that have attempted to separate effects of illness from treatment have been inconclusive. We sought to explore the separate effects of SRI use and major depressive episodes in pregnancy on risk of preterm birth...

..Efforts are needed to reduce the frequency of these risk factors in high-risk populations. Future studies, using genetically sensitive designs, are also needed to sort out the causal pathways...

..Emotional support and depression may influence adherence to risk factor management instructions after acute myocardial infarction (AMI), but their role requires further investigation...

..We then examined the power of GABHS infections and measures of psychosocial stress to predict future tic, obsessive-compulsive (OC), and depressive symptom severity...

..A group of children with Tourette syndrome and/or OC disorder without a PANDAS history served as the comparison (non-PANDAS) group...

..To determine empirically the diseases contributing most commonly and strongly to death in older adults, accounting for coexisting diseases...

..This study sought to identify and characterize major patterns of functional aging based on activities of daily living (ADL)...

..We sought to estimate differences in the risk of developing a new major depressive episode among pregnant and postpartum women with recurrent illness who either did or did not use antidepressants...

..An additional benefit of the analytical approach presented is that it allows for assessment of the utility of triggered sampling in longitudinal studies...

..We cannot exclude the possibility that the community activities of the Healthy Start program promoted increased attention to health issues among depressed women and hence enhance birth outcomes...

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..Significant benefits were found for HUD-VASH in drug and alcohol abuse outcomes that had not previously been identified...

..Findings have the potential to inform screening and intervention efforts in aging drug users with and without HIV...

..01). Our findings suggest that human skin is relatively enriched in lycopene and beta-carotene, compared to lutein and zeaxanthin, possibly reflecting a specific function of hydrocarbon carotenoids in human skin photoprotection...

..Individuals with symptom profiles not characterized by physiological dependence endorse wider range of ND criteria and have a higher likelihood of MD...

..To determine whether receipt of social supplemental security income (SSI) or Social Security disability income (SSDI) disability payments is associated with increased drug and alcohol use...

..Second-generation antipsychotics have largely replaced first-generation antipsychotics for the treatment of schizophrenia, but a large-scale cost/effectiveness analysis has not been attempted...

..The primary aim of this study was to examine whether 1 week of continuous auricular acupuncture could reduce low back and posterior pelvic pain associated with pregnancy...

..This study was designed to evaluate the psychometric properties of the YCGSI...

..A second major aim was to assess whether fluctuations in tic and OC symptom severity covaried with one another...

..Further research is needed to investigate its stability and role in predicting adolescent risk behavior over time...

..However, relatively little is known about whether similar patterns exist for other outcomes, such as health status and depressive symptoms, and whether these patterns vary by sex...

..This analysis was conducted to evaluate the association between plasma beta-carotene, alpha-carotene, lycopene, lutein/zeaxanthin, total carotenoids, retinol, alpha-tocopherol and subsequent mortality...

..Based upon studies documenting high sensitivity and specificity on the PHQ-8 and PHQ-2 in the general adult population, we hypothesized that both instruments would be effective in this population...

..The current study determined the relative efficacy of paroxetine compared to placebo in the treatment of acute postpartum MDD...

..This study was carried out to investigate whether cytokines associated with the innate immune response or T cell activation were altered under baseline conditions and during periods of symptom exacerbation...

..For these reasons, treating death as noninformative censoring of a longitudinal outcome may result in biased estimates of regression coefficients related to that outcome...

..We retrospectively investigated lymphovascular invasion as a predictive factor for biochemical failure and cancer specific survival following radical prostatectomy...

..The strength of its prognostic value for PSA recurrence makes it a potential criterion for incorporation into a future tumor, lymph node, metastasis staging system...

..43 (P<0.001). Positive-block ratio is an independent predictor of PSA recurrence and this simple method of tumor measurement seems to be promising for quantifying tumor volume if our findings are validated by subsequent reports...

..The dominance of the CLCA ligand in beta4 activation and outside-in signaling is discussed in reference to our previous report that beta4/CLCA ligation elicits selective signaling via focal adhesion kinase to promote metastatic growth...

..The objective of the current study was to determine whether the combined percentage of Gleason patterns 4 and 5 in radical prostatectomy specimens is an independent predictor of cancer-specific survival in prostate cancer patients...

..Therefore, tertiary pattern 5 should be reported in radical prostatectomy specimens...

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..Small cell carcinoma of the urinary bladder is an uncommon tumor that has been described in case reports or small series. Herein, the authors report a series of 64 patients with small cell carcinoma of the urinary bladder...

..36). A significant proportion (27%) of small cell carcinomas of the urinary bladder expressed c-kit, suggesting that it may prove useful as a therapeutic target in small cell carcinoma of the urinary bladder...

..TTF-1 positivity is not a significant prognostic factor in small cell carcinoma of the urinary bladder...

..Investigating patterns and factors associated with occurrence, deterioration, improvement and recovery of ADL and with death in older persons thus constitutes an important clinical and scientific task. ..

..Investigating patterns and factors associated with occurrence, deterioration, improvement and recovery of ADL and with death in older persons thus constitutes an important clinical and scientific task. ..

..Therefore, we state that outcomes are "attributable" to the defined risk factors or treatments. We assert only that our findings are consistent with causal hypotheses, and not that they demonstrate causality itself. ..