CHIANG SHAN LI

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Neuroimaging study of sex differences in the neuropathology of cocaine abuse
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Gend Med 2:174-82. 2005
  2. ncbi request reprint Altered performance of schizophrenia patients in an auditory detection and discrimination task: exploring the 'self-monitoring' model of hallucination
    Chiang Shan Ray Li
    Department of Psychiatry, Chang Gung Memorial Hospital, 5 Fu Hsing Street, Kwei Shan, 333 Tao Yuan, Taiwan
    Schizophr Res 55:115-28. 2002
  3. ncbi request reprint Impairment of temporal attention in patients with schizophrenia
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Tao Yuan 333, Taiwan
    Neuroreport 13:1427-30. 2002
  4. ncbi request reprint Inhibition of return in children with attention deficit hyperactivity disorder
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Taiwan
    Exp Brain Res 149:125-30. 2003
  5. ncbi request reprint A psychophysical measure of attention deficit in children with attention-deficit/hyperactivity disorder
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Abnorm Psychol 113:228-36. 2004
  6. pmc Resting state functional connectivity of the basal nucleus of Meynert in humans: in comparison to the ventral striatum and the effects of age
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA Department of Neurobiology, Yale University, New Haven, CT 06520, USA Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA Electronic address
    Neuroimage 97:321-32. 2014
  7. pmc Dissociable processes of cognitive control during error and non-error conflicts: a study of the stop signal task
    Olivia M Hendrick
    Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 5:e13155. 2010
  8. pmc Error-related functional connectivity of the habenula in humans
    Jaime S Ide
    Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Hum Neurosci 5:25. 2011
  9. pmc Improvement of quality of life in methadone treatment patients in northern Taiwan: a follow-up study
    Ying Chun Chou
    Department of Health Promotion and Health Education, National Taiwan Normal University, No 162, He ping East Road, Section 1, Taipei 10610, Taiwan
    BMC Psychiatry 13:190. 2013
  10. pmc Effects of androgen deprivation on brain function in prostate cancer patients - a prospective observational cohort analysis
    Herta H Chao
    Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT 06519, USA
    BMC Cancer 12:371. 2012

Research Grants

  1. Cognitive control and cocaine dependence
    Chiang Shan Ray Li; Fiscal Year: 2010
  2. Imaging inhibitory control in cocaine dependence
    CHIANG SHAN LI; Fiscal Year: 2006
  3. Cognitive control and cocaine dependence
    CHIANG SHAN LI; Fiscal Year: 2009

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Neuroimaging study of sex differences in the neuropathology of cocaine abuse
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Gend Med 2:174-82. 2005
    ..Female and male substance abusers differ in their disease patterns and clinical outcomes. An important question in addiction neuroscience thus concerns the neural substrates underlying these sex differences...
  2. ncbi request reprint Altered performance of schizophrenia patients in an auditory detection and discrimination task: exploring the 'self-monitoring' model of hallucination
    Chiang Shan Ray Li
    Department of Psychiatry, Chang Gung Memorial Hospital, 5 Fu Hsing Street, Kwei Shan, 333 Tao Yuan, Taiwan
    Schizophr Res 55:115-28. 2002
    ..Overall, our results do not support the idea that hallucination results from an altered bias in the online processing of perceptual signals...
  3. ncbi request reprint Impairment of temporal attention in patients with schizophrenia
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Tao Yuan 333, Taiwan
    Neuroreport 13:1427-30. 2002
    ..This observation suggests a less efficient mechanism in temporal gating of attention and in processing rapidly changing visual stimuli in schizophrenia patients...
  4. ncbi request reprint Inhibition of return in children with attention deficit hyperactivity disorder
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Taiwan
    Exp Brain Res 149:125-30. 2003
    ..These preliminary results suggest that the inhibitory attention mechanism subserving IOR is at least not fully compromised in ADHD children...
  5. ncbi request reprint A psychophysical measure of attention deficit in children with attention-deficit/hyperactivity disorder
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    J Abnorm Psychol 113:228-36. 2004
    ..The authors hypothesize that a slower closing of the attention gate may mediate this specific attention impairment in ADHD children...
  6. pmc Resting state functional connectivity of the basal nucleus of Meynert in humans: in comparison to the ventral striatum and the effects of age
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA Department of Neurobiology, Yale University, New Haven, CT 06520, USA Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA Electronic address
    Neuroimage 97:321-32. 2014
    ..These findings of age-related changes of cerebral functional connectivity of the BNM may facilitate research of the neural bases of cognitive decline in health and illness. ..
  7. pmc Dissociable processes of cognitive control during error and non-error conflicts: a study of the stop signal task
    Olivia M Hendrick
    Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 5:e13155. 2010
    ..In particular, with a procedure to elicit errors in the SST, we examined whether error and non-error control were mediated by the same pathways...
  8. pmc Error-related functional connectivity of the habenula in humans
    Jaime S Ide
    Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Hum Neurosci 5:25. 2011
    ..To our knowledge, these findings are the first to demonstrate a feedforward influence of the habenula on the VTA/SN during error detection in humans...
  9. pmc Improvement of quality of life in methadone treatment patients in northern Taiwan: a follow-up study
    Ying Chun Chou
    Department of Health Promotion and Health Education, National Taiwan Normal University, No 162, He ping East Road, Section 1, Taipei 10610, Taiwan
    BMC Psychiatry 13:190. 2013
    ..This study examined long-term improvement of quality of life amongst heroin users enrolled in methadone maintenance treatment (MMT)...
  10. pmc Effects of androgen deprivation on brain function in prostate cancer patients - a prospective observational cohort analysis
    Herta H Chao
    Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT 06519, USA
    BMC Cancer 12:371. 2012
    ....
  11. pmc Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence
    Xi Luo
    Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    Brain 136:1231-44. 2013
    ....
  12. pmc Activation of the pre-supplementary motor area but not inferior prefrontal cortex in association with short stop signal reaction time--an intra-subject analysis
    Herta H A Chao
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    BMC Neurosci 10:75. 2009
    ..Here we further pursued this functional differentiation of preSMA and rIFC on the basis of an intra-subject approach...
  13. pmc Neural correlates of post-error slowing during a stop signal task: a functional magnetic resonance imaging study
    Chiang Shan Ray Li
    Connecticut Mental Health Center, S103, Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    J Cogn Neurosci 20:1021-9. 2008
    ..These results delineate the neural circuitry specifically involved in error-associated behavioral modifications...
  14. pmc Inhibitory control and emotional stress regulation: neuroimaging evidence for frontal-limbic dysfunction in psycho-stimulant addiction
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center S103, New Haven, CT 06519, USA
    Neurosci Biobehav Rev 32:581-97. 2008
    ..Further studies that examine the functional relationships of these neural systems will likely provide the key to understanding the mechanisms underlying compulsive drug use behaviors in psycho-stimulant dependence...
  15. pmc Neural correlates of impulse control during stop signal inhibition in cocaine-dependent men
    Chiang Shan Ray Li
    Connecticut Mental Health Center, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuropsychopharmacology 33:1798-806. 2008
    ..Relative hypoactivation of the rACC during response inhibition may represent a useful neural marker of difficulties in impulse control in abstinent cocaine-dependent men who are at risk of relapse...
  16. pmc Greater activation of the "default" brain regions predicts stop signal errors
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, S103, 34 Park Street, New Haven, CT 06519, USA
    Neuroimage 38:640-8. 2007
    ....
  17. ncbi request reprint Obsessive-compulsiveness and impulsivity in a non-clinical population of adolescent males and females
    Chiang Shan Ray Li
    Medical Research Center, Chang Gung Memorial Hospital, Tao Yuan, Taiwan
    Psychiatry Res 149:129-38. 2007
    ..We discuss the relevance of these findings to developing a conceptual scheme to characterize and study the neurobiological basis of obsessive-compulsive and impulsive behaviors...
  18. pmc Subcortical processes of motor response inhibition during a stop signal task
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University, New Haven, Connecticut 06519, USA
    Neuroimage 41:1352-63. 2008
    ..Thus, fMRI delineated contrasting roles of the prefrontal-caudate and striato-thalamic activities in mediating motor response inhibition...
  19. pmc Error-specific medial cortical and subcortical activity during the stop signal task: a functional magnetic resonance imaging study
    C S R Li
    Department of Psychiatry, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuroscience 155:1142-51. 2008
    ..The results also suggest that the relationship between error-related activity and post-error behavioral adjustment may be more complicated than has been conceptualized by the conflict monitoring hypothesis...
  20. pmc Neural correlates of speeded as compared with delayed responses in a stop signal task: an indirect analog of risk taking and association with an anxiety trait
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine and VA Connecticut Healthcare System, New Haven, 06519, USA
    Cereb Cortex 19:839-48. 2009
    ..These results thus delineated, for the first time, a neural analog of risk taking during stop signal performance, highlighting a novel aspect and broadening the utility of this behavioral paradigm...
  21. pmc Altered impulse control in alcohol dependence: neural measures of stop signal performance
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University, New Haven, Connecticut 06519, USA
    Alcohol Clin Exp Res 33:740-50. 2009
    ..In particular, we examined the processes of risk taking and cognitive control as the neural endophenotypes of alcohol dependence...
  22. pmc Increased error-related thalamic activity during early compared to late cocaine abstinence
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519 USA
    Drug Alcohol Depend 109:181-9. 2010
    ..These findings support the hypothesis that heightened thalamic reactivity to salient stimuli co-occur with cocaine craving and loss of self control...
  23. pmc Biological markers of the effects of intravenous methylphenidate on improving inhibitory control in cocaine-dependent patients
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA
    Proc Natl Acad Sci U S A 107:14455-9. 2010
    ..Altered ventromedial prefrontal activation and increased blood pressure may represent useful CNS and peripheral biomarkers in individualized treatment with methylphenidate for patients with cocaine dependence...
  24. ncbi request reprint Motor response inhibition in children with Tourette's disorder
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    J Neuropsychiatry Clin Neurosci 18:417-9. 2006
    ..These results suggest the importance of considering motor tics as voluntary rather than as involuntary...
  25. ncbi request reprint Gender differences in the neural correlates of response inhibition during a stop signal task
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA
    Neuroimage 32:1918-29. 2006
    ..Men activated the motor circuitry while women appeared to involve visual association or habit learning during stop signal performance...
  26. ncbi request reprint Inhibition of return in temporal order saccades
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Tao Yuan, Taiwan
    Vision Res 42:2089-93. 2002
    ..Here we demonstrate that IOR can be observed in a temporal order saccade task where eye movement instead of manual response is used to select the target. The result suggests the importance of monitoring eye movement in studies of IOR...
  27. ncbi request reprint Impaired detection of visual motion in schizophrenia patients
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, and Department of Psychiatry, Chang Gung Memorial Hospital, Kwei shai, Tao Yuan, Taiwan
    Prog Neuropsychopharmacol Biol Psychiatry 26:929-34. 2002
    ..Here, we investigated whether these patients showed a similar deficit in another sensory modality. Specifically, we examined a subset of the schizophrenia patients in a visual task involving motion detection...
  28. ncbi request reprint Auditory discrimination in female adolescents varying in schizotypal features: preliminary findings
    Chiang Shan Ray Li
    Department of Psychiatry and Medical Research Center, Chang Gung Memorial Hospital and Graduate Institute of Behavioral Science, Chang Gung University, Taipei, Taiwan
    Psychiatry Clin Neurosci 57:391-7. 2003
    ..Second, the three groups of subjects did not differ in the response bias. This latter finding provides evidence at odds with the 'self-monitoring' model of auditory hallucination...
  29. ncbi request reprint Attentional blink in adolescents with varying levels of impulsivity
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Tao Yuan, Taiwan
    J Psychiatr Res 39:197-205. 2005
    ..Taken together, these findings suggest impairment in temporal attention in adolescents with high impulsivity. As in ADHD children, a gating deficit may play a central role in this attention impairment...
  30. ncbi request reprint Do schizophrenia patients make more perseverative than non-perseverative errors on the Wisconsin Card Sorting Test? A meta-analytic study
    Chiang Shan Ray Li
    Connecticut Mental Health Center, Department of Psychiatry, Yale University, Rm S103, 34 Park Street, New Haven, CT 06519, USA
    Psychiatry Res 129:179-90. 2004
    ....
  31. ncbi request reprint Sex differences in brain activation during stress imagery in abstinent cocaine users: a functional magnetic resonance imaging study
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University, New Haven, Connecticut 06519, USA
    Biol Psychiatry 57:487-94. 2005
    ....
  32. ncbi request reprint Antisocial personality and stress-induced brain activation in cocaine-dependent patients
    Chiang Shan R Li
    Department of Psychiatry, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Neuroreport 17:243-7. 2006
    ..These results highlight important sex differences in the association between antisocial personality and distress processing in cocaine-dependent individuals...
  33. ncbi request reprint Fore-period effect and stop-signal reaction time
    Chiang Shan Ray Li
    Connecticut Mental Health Center, S103 Department of Psychiatry, Yale University, 34 Park Street, New Haven, 06519, USA
    Exp Brain Res 167:305-9. 2005
    ..This finding suggests that response readiness needs to be accounted for in examining response inhibition in a stop-signal task...
  34. ncbi request reprint Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S103, 34 Park Street, New Haven, CT 06519, USA
    Psychiatry Res 140:271-80. 2005
    ..The results suggest an abnormal cognitive control mechanism during affective processing in association with heavy cannabis use...
  35. ncbi request reprint Imaging response inhibition in a stop-signal task: neural correlates independent of signal monitoring and post-response processing
    Chiang Shan Ray Li
    Department of Psychiatry, Magnetic Resonance Research Center, Yale University, New Haven, Connecticut 06519, USA
    J Neurosci 26:186-92. 2006
    ..These brain regions may represent the neural substrata of response inhibition independent of other cognitive and affective functions...
  36. pmc Alexithymia and stress-induced brain activation in cocaine-dependent men and women
    Chiang Shan Ray Li
    Connecticut Mental Health Center, Department of Psychiatry, Yale University, New Haven, Connecticut 06519, USA
    J Psychiatry Neurosci 31:115-21. 2006
    ..Both stress and an alexithymic response to stress can contribute to relapse into drug abuse, but to our knowledge the neural processing of an alexithymic response to stress in cocaine-dependent individuals has not been examined...
  37. ncbi request reprint Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence
    Chiang Shan Ray Li
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA
    Drug Alcohol Depend 85:205-12. 2006
    ..These results suggest that diminished performance monitoring can be a critical cognitive mechanism underlying impaired response inhibition in cocaine dependent patients...
  38. ncbi request reprint A perceptual level mechanism of the inhibition of return in oculomotor planning
    Chiang Shan Ray Li
    Brain and Behavior Laboratory, Medical Research Center, Chang Gung Memorial Hospital, Tao Yuan, Taiwan
    Brain Res Cogn Brain Res 14:269-76. 2002
    ..We discuss the implications of these results for attention gating of perceptual inputs and for mechanisms of visuomotor control...
  39. ncbi request reprint Oculomotor correlates of context-guided learning in visual search
    Yuan Chi Tseng
    Chang Gung Memorial Hospital, Tao Yuan, Taiwan
    Percept Psychophys 66:1363-78. 2004
    ..Most important, the speed with which eye fixation approached the target did not change as a result of learning. We discuss the general implications of these results for visual search...
  40. ncbi request reprint Neuronal activity in the supplementary motor area of monkeys adapting to a new dynamic environment
    Camillo Padoa-Schioppa
    McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Neurophysiol 91:449-73. 2004
    ..We show that neurons in SMA reflect the movement dynamics individually and as a population, and that their activity undergoes a variety of plastic changes when monkeys adapt to a new dynamic environment...

Research Grants4

  1. Cognitive control and cocaine dependence
    Chiang Shan Ray Li; Fiscal Year: 2010
    ..The results gathered from the proposed projects will help us understand the "cocaine- dependent brain" and facilitate the development of novel therapeutic strategies to treat patients with cocaine dependence. ..
  2. Imaging inhibitory control in cocaine dependence
    CHIANG SHAN LI; Fiscal Year: 2006
    ..The results gathered from the proposed projects will help us understand the "cocaine-dependent brain" and facilitate the development of novel therapeutic strategies to treat patients with cocaine dependence. ..
  3. Cognitive control and cocaine dependence
    CHIANG SHAN LI; Fiscal Year: 2009
    ..The results gathered from the proposed projects will help us understand the "cocaine- dependent brain" and facilitate the development of novel therapeutic strategies to treat patients with cocaine dependence. ..