Research Topics

Philippe Lefrançois

Affiliation: Yale University

Country: USA

Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing
Philippe Lefrançois
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA
BMC Genomics 10:37. 2009
Mapping accessible chromatin regions using Sono-Seq
Raymond K Auerbach
Program in Computational Biology, Yale University, New Haven, CT 06520, USA
Proc Natl Acad Sci U S A 106:14926-31. 2009
ChIP-Seq using high-throughput DNA sequencing for genome-wide identification of transcription factor binding sites
Philippe Lefrançois
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA
Methods Enzymol 470:77-104. 2010

Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing
Philippe Lefrançois
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA
BMC Genomics 10:37. 2009
....
Mapping accessible chromatin regions using Sono-Seq
Raymond K Auerbach
Program in Computational Biology, Yale University, New Haven, CT 06520, USA
Proc Natl Acad Sci U S A 106:14926-31. 2009
..Furthermore, our results provide insights into the mapping of binding sites by using ChIP-Seq experiments and the value of reference samples that should be used in such experiments...
ChIP-Seq using high-throughput DNA sequencing for genome-wide identification of transcription factor binding sites
Philippe Lefrançois
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA
Methods Enzymol 470:77-104. 2010
..The use of multiplex short-read sequencing (i.e., barcoding) enables the analysis of many ChIP samples simultaneously, which is especially valuable for organisms with small genomes such as yeast...