Affiliation: Yale University
- Ontologies for proteomics: towards a systematic definition of structure and function that scales to the genome levelNing Lan
Department of Molecular Biophysics, New Haven, CT 06520, USA
Curr Opin Chem Biol 7:44-54. 2003....
- Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysisChern Sing Goh
Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Ave, New Haven, CT 06520, USA
J Mol Biol 336:115-30. 2004..This information may prove useful in optimizing high-throughput experimentation. Further information is available from http://mining.nesg.org/...
- Integration of genomic datasets to predict protein complexes in yeastRonald Jansen
Department of Molecular Biophysics and Biochemistry, 266 Whitney Avenue, Yale University, PO Box 208114, New Haven, CT 06520, USA
J Struct Funct Genomics 2:71-81. 2002..Supplementary information is available at http:// bioinfo.mbb.yale.edu/integrate/interactions/...
- A small reservoir of disabled ORFs in the yeast genome and its implications for the dynamics of proteome evolutionPaul Harrison
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520 8114, USA
J Mol Biol 316:409-19. 2002..See genecensus.org/pseudogene for further information.)..
- SPINE 2: a system for collaborative structural proteomics within a federated database frameworkChern Sing Goh
Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520, USA
Nucleic Acids Res 31:2833-8. 2003..g. crystallization LIMS local to particular laboratories) and (iii) international archival resources that SPINE links to and passes on information to (e.g. TargetDB at the PDB)...
- Proteomics. Integrating interactomesMark Gerstein
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
Science 295:284-7. 2002
- An integrated approach for finding overlooked genes in yeastAnuj Kumar
Department of Molecular, Cellular, and Developmental Biology, Yale University, P O Box 208103, New Haven, CT 06520 8103, USA
Nat Biotechnol 20:58-63. 2002..In total, the genes discovered using this approach constitute 2% of the yeast genome and represent a wealth of overlooked biology...
- The protein target list of the Northeast Structural Genomics ConsortiumZeba Wunderlich
Proteins 56:181-7. 2004
- Functional profiling of the Saccharomyces cerevisiae genomeGuri Giaever
Stanford Genome Technology Center, Stanford University, Palo Alto, California 94304, USA
Nature 418:387-91. 2002..Our results validate the yeast gene-deletion collection as a valuable resource for functional genomics...
- Strategies for structural proteomics of prokaryotes: Quantifying the advantages of studying orthologous proteins and of using both NMR and X-ray crystallography approachesAlexei Savchenko
Ontario Center for Structural Proteomics, University Health Network, Toronto, Ontario, Canada
Proteins 50:392-9. 2003....