HARLAN MARC KRUMHOLZ

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint A taxonomy for disease management: a scientific statement from the American Heart Association Disease Management Taxonomy Writing Group
    Harlan M Krumholz
    Yale University, USA
    Circulation 114:1432-45. 2006
  2. pmc Variation exists in rates of admission to intensive care units for heart failure patients across hospitals in the United States
    Kyan C Safavi
    Yale University School of Medicine, New Haven, CT, USA
    Circulation 127:923-9. 2013
  3. pmc Relationship between hospital readmission and mortality rates for patients hospitalized with acute myocardial infarction, heart failure, or pneumonia
    Harlan M Krumholz
    Department of Internal Medicine Section of Cardiovascular Medicine, Yale University School of Medicine, 1 Church St, Ste 200, New Haven, CT 06510, USA
    JAMA 309:587-93. 2013
  4. pmc Research in action: using positive deviance to improve quality of health care
    Elizabeth H Bradley
    Division of Health Policy and Administration, School of Public Health, Yale University School of Medicine, New Haven, CT, USA
    Implement Sci 4:25. 2009
  5. pmc Contemporary evidence: baseline data from the D2B Alliance
    Elizabeth H Bradley
    Section of Health Policy and Administration, School of Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    BMC Res Notes 1:23. 2008
  6. pmc Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 12:127. 2011
  7. pmc Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 9:66. 2008
  8. pmc Inputs to quality: supervision, management, and community involvement in health facilities in Egypt in 2004
    Emily J Cherlin
    Section of Health Policy and Administration, School of Public Health, New Haven, CT, USA
    BMC Health Serv Res 11:282. 2011
  9. pmc Volume-based referral for cardiovascular procedures in the United States: a cross-sectional regression analysis
    Andrew J Epstein
    Division of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    BMC Health Serv Res 5:42. 2005
  10. pmc Increased mortality among survivors of myocardial infarction with kidney dysfunction: the contribution of gaps in the use of guideline-based therapies
    Pamela N Peterson
    Denver Health Medical Center, Denver, Colorado, USA
    BMC Cardiovasc Disord 9:29. 2009

Research Grants

  1. Young Women With Acute Myocardial Infarction
    Harlan Krumholz; Fiscal Year: 2007
  2. Telemonitoring to improve heart failure outcomes
    Harlan Krumholz; Fiscal Year: 2007
  3. Strategies to reduce time to reperfusion therapy for MI
    Harlan Krumholz; Fiscal Year: 2005
  4. HOSPITAL PERFORMANCE & BETA-BLOCKER USE AFTER AMI
    Harlan Krumholz; Fiscal Year: 2001
  5. Young Women With Acute Myocardial Infarction
    HARLAN MARC KRUMHOLZ; Fiscal Year: 2010

Detail Information

Publications118 found, 100 shown here

  1. ncbi request reprint A taxonomy for disease management: a scientific statement from the American Heart Association Disease Management Taxonomy Writing Group
    Harlan M Krumholz
    Yale University, USA
    Circulation 114:1432-45. 2006
    ....
  2. pmc Variation exists in rates of admission to intensive care units for heart failure patients across hospitals in the United States
    Kyan C Safavi
    Yale University School of Medicine, New Haven, CT, USA
    Circulation 127:923-9. 2013
    ..We characterized hospital patterns of ICU admission for patients with HF and determined their association with the use of ICU-level therapies and patient outcomes...
  3. pmc Relationship between hospital readmission and mortality rates for patients hospitalized with acute myocardial infarction, heart failure, or pneumonia
    Harlan M Krumholz
    Department of Internal Medicine Section of Cardiovascular Medicine, Yale University School of Medicine, 1 Church St, Ste 200, New Haven, CT 06510, USA
    JAMA 309:587-93. 2013
    ..The evaluation of hospital performance as measured by RSMRs and RSRRs has not been well characterized...
  4. pmc Research in action: using positive deviance to improve quality of health care
    Elizabeth H Bradley
    Division of Health Policy and Administration, School of Public Health, Yale University School of Medicine, New Haven, CT, USA
    Implement Sci 4:25. 2009
    ..CONCLUSION: The identification and examination of health care organizations that demonstrate positive deviance provides an opportunity to characterize and disseminate strategies for improving quality...
  5. pmc Contemporary evidence: baseline data from the D2B Alliance
    Elizabeth H Bradley
    Section of Health Policy and Administration, School of Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    BMC Res Notes 1:23. 2008
    ..This study presents data on (1) the prevalence of evidence-based strategies in U.S. hospitals that participated in the D2B Alliance and (2) identifies key hospital characteristics associated with their use...
  6. pmc Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 12:127. 2011
    ..Genome-wide association studies (GWAS) have identified new candidate genes for the occurrence of acute coronary syndrome (ACS), but possible effects of such genes on survival following ACS have yet to be investigated...
  7. pmc Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 9:66. 2008
    ..Many candidate genes have been reported to be risk factors for acute coronary syndrome (ACS), but their impact on clinical prognosis following ACS is unknown...
  8. pmc Inputs to quality: supervision, management, and community involvement in health facilities in Egypt in 2004
    Emily J Cherlin
    Section of Health Policy and Administration, School of Public Health, New Haven, CT, USA
    BMC Health Serv Res 11:282. 2011
    ....
  9. pmc Volume-based referral for cardiovascular procedures in the United States: a cross-sectional regression analysis
    Andrew J Epstein
    Division of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    BMC Health Serv Res 5:42. 2005
    ..In addition to hospital risk-adjusted mortality standards, the Leapfrog Group recommends annual hospital procedure minimums of 450 for CABG and 400 for PCI to reduce procedure-associated mortality...
  10. pmc Increased mortality among survivors of myocardial infarction with kidney dysfunction: the contribution of gaps in the use of guideline-based therapies
    Pamela N Peterson
    Denver Health Medical Center, Denver, Colorado, USA
    BMC Cardiovasc Disord 9:29. 2009
    ..We assessed the degree to which differences in guideline-based medical therapy for acute myocardial infarction (AMI) contribute to the higher mortality associated with kidney disease...
  11. pmc An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation
    Christopher S Coffey
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    BMC Bioinformatics 5:49. 2004
    ..One advantage of the MDR method is that it provides an internal prediction error for validation. We summarize our use of this internal prediction error for model validation...
  12. ncbi request reprint The year in epidemiology, health services, and outcomes research
    Harlan M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, Center for Outcomes Research and Evaluation, Yale New Haven Health, New Haven, Connecticut 06520 8088, USA
    J Am Coll Cardiol 46:1362-70. 2005
  13. ncbi request reprint An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with an acute myocardial infarction
    Harlan M Krumholz
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Circulation 113:1683-92. 2006
    ..We sought to develop a hierarchical regression model using Medicare claims data that produces hospital risk-standardized 30-day mortality rates and to validate the hospital estimates against those derived from a medical record model...
  14. ncbi request reprint Report of the National Heart, Lung, and Blood Institute working group on outcomes research in cardiovascular disease
    Harlan M Krumholz
    Department of Medicine, Yale University School of Medicine, Yale New Haven Health Center for Outcomes Research and Evaluation, New Haven, CT, USA
    Circulation 111:3158-66. 2005
    ..The working group concluded that a dedicated investment in CV outcomes research could directly improve the care delivered in the United States...
  15. ncbi request reprint Knowledge of cholesterol levels and targets in patients with coronary artery disease
    Susan Cheng
    Yale University School of Medicine, 333 Cedar Street, Room I 456 SHM P O Box 208088, New Haven, CT 06520 8088, USA
    Prev Cardiol 8:11-7. 2005
    ..These findings suggest that current cholesterol education efforts appear inadequate, particularly for women, nonwhites, and patients without any college education...
  16. doi request reprint A campaign to improve the timeliness of primary percutaneous coronary intervention: Door-to-Balloon: An Alliance for Quality
    Harlan M Krumholz
    Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, 333 Cedar Street, New Haven, CA 06520 8088, USA
    JACC Cardiovasc Interv 1:97-104. 2008
    ....
  17. ncbi request reprint The year in health care delivery and outcomes research
    Harlan M Krumholz
    Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8088, USA
    J Am Coll Cardiol 44:1130-6. 2004
  18. ncbi request reprint An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with heart failure
    Harlan M Krumholz
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Circulation 113:1693-701. 2006
    ..A model using administrative claims data that is suitable for profiling hospital performance for heart failure would be useful in quality assessment and improvement efforts...
  19. ncbi request reprint The year in epidemiology, health services research, and outcomes research
    Harlan M Krumholz
    Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8088, USA
    J Am Coll Cardiol 48:1886-95. 2006
  20. ncbi request reprint Measuring performance for treating heart attacks and heart failure: the case for outcomes measurement
    Harlan M Krumholz
    Yale University School of Medicine, New Haven, Connecticut, USA
    Health Aff (Millwood) 26:75-85. 2007
    ..Recent developments in the methodology and standards for outcomes measurement have laid the groundwork for incorporating outcomes into performance monitoring efforts for these conditions...
  21. pmc What have we learnt from Vioxx?
    Harlan M Krumholz
    Department of Medicine, Yale University School of Medicine, 333 Cedar Street, PO Box 208088, New Haven, CT 06520 8088, USA
    BMJ 334:120-3. 2007
  22. pmc Improvements in door-to-balloon time in the United States, 2005 to 2010
    Harlan M Krumholz
    Department of Internal Medicine, Yale University School of Medicine, 1 Church St, Ste 200, New Haven, CT 06510, USA
    Circulation 124:1038-45. 2011
    ..Moreover, we do not know whether improvements in door-to-balloon times were shared equally among patient and hospital groups...
  23. pmc An administrative claims measure suitable for profiling hospital performance based on 30-day all-cause readmission rates among patients with acute myocardial infarction
    Harlan M Krumholz
    Section of Cardiovascular Medicine and Robert Wood Johnson Clinical Scholars Program, Department of Internal Medicine, and School of Public Health, Yale University School of Medicine, New Haven, CT 06510, USA
    Circ Cardiovasc Qual Outcomes 4:243-52. 2011
    ....
  24. doi request reprint Patterns of hospital performance in acute myocardial infarction and heart failure 30-day mortality and readmission
    Harlan M Krumholz
    Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
    Circ Cardiovasc Qual Outcomes 2:407-13. 2009
    ..We provide patterns of hospital performance, based on these measures...
  25. pmc Reduction in acute myocardial infarction mortality in the United States: risk-standardized mortality rates from 1995-2006
    Harlan M Krumholz
    Section of Cardiovascular Medicine, Yale University School of Medicine, 1 Church St, Ste 200, New Haven, CT 06510, USA
    JAMA 302:767-73. 2009
    ..However, little has been reported about improvements in hospital short-term mortality rates or reductions in between-hospital variation in short-term mortality rates...
  26. doi request reprint Public reporting of 30-day mortality for patients hospitalized with acute myocardial infarction and heart failure
    Harlan M Krumholz
    Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Circulation 118:1394-7. 2008
  27. doi request reprint Outcomes research: generating evidence for best practice and policies
    Harlan M Krumholz
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Circulation 118:309-18. 2008
  28. ncbi request reprint The year in epidemiology, health services research, and outcomes research
    Harlan M Krumholz
    Section of Cardiovascular Medicine and the Robert Wood Johnson Clinical Scholars Program, Department of Medicine, New Haven, Connecticut 06520 8088, USA
    J Am Coll Cardiol 50:2254-62. 2007
  29. doi request reprint National performance on door-in to door-out time among patients transferred for primary percutaneous coronary intervention
    Jeph Herrin
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Arch Intern Med 171:1879-86. 2011
    ..We sought to describe national performance in DIDO time using a new measure developed by the Centers for Medicare & Medicaid Services...
  30. ncbi request reprint Financial barriers to health care and outcomes after acute myocardial infarction
    Ali R Rahimi
    Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    JAMA 297:1063-72. 2007
    ..The prevalence and consequences of financial barriers to health care services and medications are not well documented for patients with an acute myocardial infarction (AMI)...
  31. ncbi request reprint Is there evidence of implicit exclusion criteria for elderly subjects in randomized trials? Evidence from the GUSTO-1 study
    Harlan M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    Am Heart J 146:839-47. 2003
    ....
  32. ncbi request reprint Variations in and correlates of length of stay in academic hospitals among patients with heart failure resulting from systolic dysfunction
    H M Krumholz
    Yale University School of Medicine, New Haven, CT, USA
    Am J Manag Care 5:715-23. 1999
    ..We sought to identify factors associated with length of stay among patients admitted for the treatment of heart failure resulting from systolic dysfunction...
  33. ncbi request reprint National use and effectiveness of beta-blockers for the treatment of elderly patients after acute myocardial infarction: National Cooperative Cardiovascular Project
    H M Krumholz
    Department of Medicine, Yale School of Medicine, and the Yale New Haven Hospital Center for Outcomes Research and Evaluation, CT 06520 8025, USA
    JAMA 280:623-9. 1998
    ..Despite the importance of beta-blockers for secondary prevention after acute myocardial infarction (AMI), several studies have suggested that they are substantially underutilized, particularly in older patients...
  34. ncbi request reprint Resuscitation preferences among patients with severe congestive heart failure: results from the SUPPORT project. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments
    H M Krumholz
    Department of Medicine, Yale School of Medicine and the Yale New Haven Hospital Center for Outcomes Research and Evaluation, Conn 06520 8025, USA
    Circulation 98:648-55. 1998
    ..We sought to describe the resuscitation preferences of patients hospitalized with an exacerbation of severe congestive heart failure, perceptions of those preferences by their physicians, and the stability of the preferences...
  35. ncbi request reprint Early beta-blocker therapy for acute myocardial infarction in elderly patients
    H M Krumholz
    Yale University School of Medicine and the Yale New Haven Hospital, Center for Outcomes Research and Evaluation, Connecticut 06520 8025, USA
    Ann Intern Med 131:648-54. 1999
    ..Despite the evidence supporting the importance of early beta-blocker therapy, this intervention has received little attention as an indicator of quality of care...
  36. ncbi request reprint Predictors of readmission among elderly survivors of admission with heart failure
    H M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, The Yale University School of Medicine, New Haven, Connecticut, USA
    Am Heart J 139:72-7. 2000
    ..Identifying factors to predict risk of readmission in these patients could help clinicians focus resource-intensive disease management efforts on the high-risk patients...
  37. ncbi request reprint Correlates and impact on outcomes of worsening renal function in patients > or =65 years of age with heart failure
    H M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8025, USA
    Am J Cardiol 85:1110-3. 2000
    ....
  38. ncbi request reprint Use and effectiveness of intravenous heparin therapy for treatment of acute myocardial infarction in the elderly
    H M Krumholz
    Section of Cardiovascular Medicine, Yale School of Medicine, Yale University, Yale New Haven Hospital Center for Outcomes Research and Evaluation, Connecticut 06520 8025, USA
    J Am Coll Cardiol 31:973-9. 1998
    ....
  39. ncbi request reprint Aspirin and angiotensin-converting enzyme inhibitors among elderly survivors of hospitalization for an acute myocardial infarction
    H M Krumholz
    Yale University School of Medicine, 333 Cedar St, PO Box 208025, New Haven, CT 06520 8025, USA
    Arch Intern Med 161:538-44. 2001
    ....
  40. ncbi request reprint Admission to hospitals with on-site cardiac catheterization facilities :impact on long-term costs and outcomes
    H M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, Section of Chronic Disease Epidemiology, Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8025, USA
    Circulation 98:2010-6. 1998
    ....
  41. ncbi request reprint Trends in the quality of care for Medicare beneficiaries admitted to the hospital with unstable angina
    H M Krumholz
    Section of Cardiovascular Medicine, Yale School of Medicine, Yale New Haven Hospital, CT 06520 8025, USA
    J Am Coll Cardiol 31:957-63. 1998
    ....
  42. ncbi request reprint Prognostic importance of emotional support for elderly patients hospitalized with heart failure
    H M Krumholz
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8025, USA
    Circulation 97:958-64. 1998
    ..To address this issue, we sought to determine whether emotional support is associated with fatal and nonfatal cardiovascular events in elderly patients hospitalized with heart failure...
  43. ncbi request reprint Clinical correlates of in-hospital costs for acute myocardial infarction in patients 65 years of age and older
    H M Krumholz
    Department of Medicine, Yale New Haven Hospital Center for Outcomes Research and Evaluation, Yale School of Medicine, CT 06520 8025, USA
    Am Heart J 135:523-31. 1998
    ..Although several demographic and clinical characteristics were significantly associated with cost, they accounted for only 7% of the variation. In-hospital procedures and adverse outcomes accounted for 53% of the variation...
  44. ncbi request reprint Quality of care for elderly patients hospitalized with heart failure
    H M Krumholz
    Department of Medicine, Yale School of Medicine, New Haven, Conn, USA
    Arch Intern Med 157:2242-7. 1997
    ..However, despite this interest, there is a paucity of information about the care of these patients in actual clinical practice across diverse sites...
  45. ncbi request reprint Aspirin and the treatment of heart failure in the elderly
    H M Krumholz
    Yale University School of Medicine, 333 Cedar St, PO Box 208025, New Haven, CT 06520 8025, USA
    Arch Intern Med 161:577-82. 2001
    ....
  46. ncbi request reprint Comparing AMI mortality among hospitals in patients 65 years of age and older: evaluating methods of risk adjustment
    H M Krumholz
    Sections of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    Circulation 99:2986-92. 1999
    ..Interest in the reporting of risk-adjusted outcomes for patients with acute myocardial infarction is growing. A useful risk-adjustment model must balance parsimony and ease of data collection with predictive ability...
  47. pmc Survival after acute myocardial infarction (SAMI) study: the design and implementation of a positive deviance study
    Harlan M Krumholz
    Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
    Am Heart J 162:981-987.e9. 2011
    ..This type of study, using a positive deviance approach and mixed-methods design, can generate and test hypotheses about factors most strongly associated with exemplary performance based on practices currently in use...
  48. ncbi request reprint Effects of age on the quality of care provided to older patients with acute myocardial infarction
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med 114:307-15. 2003
    ..Furthermore, it is unclear whether age-associated variations in care are similar or vary among treatments...
  49. ncbi request reprint Association between functional status and use and effectiveness of beta-blocker prophylaxis in elderly survivors of acute myocardial infarction
    Gail Vitagliano
    Department of Medicine, School of Medicine, Yale University, New Haven, and Clinical Epidemiology Unit, Veterans Affairs Connecticuat Healthcare System, West Haven, Connecticut, USA
    J Am Geriatr Soc 52:495-501. 2004
    ..To examine whether physical and cognitive impairments explain low use of beta-blockers in elderly patients and whether functionally impaired older adults have improved survival if a beta-blocker is prescribed at hospital discharge...
  50. ncbi request reprint Efficacy and safety of two unfractionated heparin dosing strategies with tenecteplase in acute myocardial infarction (results from Assessment of the Safety and Efficacy of a New Thrombolytic Regimens 2 and 3)
    Jeptha P Curtis
    Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Cardiol 94:279-83. 2004
    ..49, 95% CI 0.35 to 0.67) than did patients in ASSENT-2. These findings support the use of smaller dose, weight-adjusted heparin in patients with ST-elevation myocardial infarction treated with tenecteplase...
  51. pmc Sex and racial differences in the management of acute myocardial infarction, 1994 through 2002
    Viola Vaccarino
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    N Engl J Med 353:671-82. 2005
    ..Although increased attention has been paid to sex and racial differences in the management of myocardial infarction, it is unknown whether these differences have narrowed over time...
  52. ncbi request reprint The impact of socioeconomic status and race on trial participation for older women with breast cancer
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Robert Wood Johnson Clinical Scholars Program, New Haven, Connecticut, USA
    Cancer 103:483-91. 2005
    ..Although socioeconomic status (SES) is associated with both race and age, to the authors' knowledge little is known regarding the impact of SES on trial enrollment among older women with breast cancer...
  53. ncbi request reprint Race, quality of care, and outcomes of elderly patients hospitalized with heart failure
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520 8025, USA
    JAMA 289:2517-24. 2003
    ..Because previous studies have been based on selected patient populations treated more than a decade ago, it is unclear if racial differences in quality of care and outcomes currently exist in the United States...
  54. ncbi request reprint Characteristics of physician leaders working to improve the quality of care in acute myocardial infarction
    Eric S Holmboe
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Jt Comm J Qual Saf 29:289-96. 2003
    ..A taxonomy of the characteristics of the physician quality leader from the perspective of physicians and nonphysicians was developed...
  55. ncbi request reprint Hospital-level performance improvement: beta-blocker use after acute myocardial infarction
    Elizabeth H Bradley
    Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Care 42:591-9. 2004
    ....
  56. ncbi request reprint Sex differences in health status after coronary artery bypass surgery
    Viola Vaccarino
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, 1256 Briarcliff Rd, Suite 1 North, Atlanta, GA 30306, USA
    Circulation 108:2642-7. 2003
    ..Although previous studies have shown functional improvements in patients who undergo coronary artery bypass graft (CABG) surgery, data are conflicting on whether the gains achieved by women are similar to or less than those achieved by men...
  57. pmc Hospital coronary artery bypass graft surgery volume and patient mortality, 1998-2000
    Saif S Rathore
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
    Ann Surg 239:110-7. 2004
    ..To evaluate the association between annual hospital coronary artery bypass graft (CABG) surgery volume and in-hospital mortality...
  58. doi request reprint Association of early follow-up after acute myocardial infarction with higher rates of medication use
    Stacie L Daugherty
    Department of Medicine, Division of Cardiology, University of Colorado Denver Health Sciences Center, Denver, CO, USA
    Arch Intern Med 168:485-91; discussion 492. 2008
    ..Early outpatient follow-up after acute myocardial infarction (AMI) is recommended in guidelines, but its relationship with the use of evidence-based therapies is unknown...
  59. ncbi request reprint Social support as a predictor of participation in cardiac rehabilitation after coronary artery bypass graft surgery
    Liudmila Husak
    Department of Medicine, Emory University School of Medicine, Atlanta, GA 30306, USA
    J Cardiopulm Rehabil 24:19-26. 2004
    ..The purpose of this study was to investigate the role of social support as an independent predictor of participation in cardiac rehabilitation...
  60. ncbi request reprint Differences between African Americans and whites in the outcome of heart failure: Evidence for a greater functional decline in African Americans
    Viola Vaccarino
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Am Heart J 143:1058-67. 2002
    ..This might, in part, reflect a poorer course of heart failure among African Americans...
  61. ncbi request reprint Quality improvement efforts and hospital performance: rates of beta-blocker prescription after acute myocardial infarction
    Elizabeth H Bradley
    Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8025, USA
    Med Care 43:282-92. 2005
    ..Hospitals are under increasing pressure to measure and improve quality of care, and substantial resources are being directed at a variety of quality improvement strategies; however, the evidence base supporting these strategies is limited...
  62. ncbi request reprint Quality of care for acute myocardial infarction in elderly patients with alcohol-related diagnoses
    David A Fiellin
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8088, USA
    Alcohol Clin Exp Res 30:70-5. 2006
    ..We sought to determine whether elderly patients with alcohol-related diagnoses are less likely to receive standard indicators of quality care for acute myocardial infarction...
  63. pmc Sex, quality of care, and outcomes of elderly patients hospitalized with heart failure: findings from the National Heart Failure Project
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn, USA
    Am Heart J 149:121-8. 2005
    ..However, these studies were based upon selected patient populations and lacked quality of care measures...
  64. ncbi request reprint Predictors of cardiologist care for older patients hospitalized for heart failure
    JoAnne Micale Foody
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520 8025, USA
    Am Heart J 147:66-73. 2004
    ..However, national rates of specialty care during hospitalization for heart failure and factors associated with care by a cardiologist are unknown...
  65. ncbi request reprint Hospital quality for acute myocardial infarction: correlation among process measures and relationship with short-term mortality
    Elizabeth H Bradley
    Department of Epidemiology and Public Health, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    JAMA 296:72-8. 2006
    ....
  66. ncbi request reprint Time course of depression and outcome of myocardial infarction
    Susmita Parashar
    Divisions of General Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Intern Med 166:2035-43. 2006
    ..Our objective was to evaluate the prognostic importance of transient, new, or persistent depression on outcomes at 6 months after MI...
  67. ncbi request reprint Trends in acute myocardial infarction in 4 US states between 1992 and 2001: clinical characteristics, quality of care, and outcomes
    Frederick A Masoudi
    Department of Medicine, Denver Health Medical Center, 777 Bannock St, Denver, CO 80204, USA
    Circulation 114:2806-14. 2006
    ..Long-term trends in the clinical characteristics, quality of care, and outcomes for AMI over time from the health system perspective in geographically diverse populations are not well known...
  68. ncbi request reprint Sex differences in cardiac catheterization after acute myocardial infarction: the role of procedure appropriateness
    Saif S Rathore
    Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, Room I 456 SHM, PO Box 208025, New Haven, CT 06520 8025, USA
    Ann Intern Med 137:487-93. 2002
    ..Many studies have found that women are less likely than men to have cardiac catheterization after an acute myocardial infarction; however, it is unknown whether sex differences reflect inappropriate treatment...
  69. ncbi request reprint Race and sex differences in the refusal of cardiac catheterization among elderly patients hospitalized with acute myocardial infarction
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520 8025, USA
    Am Heart J 144:1052-6. 2002
    ..It is unclear whether race or sex differences in procedure refusal may contribute to this difference. We sought to determine whether cardiac catheterization refusal rates differ by patient race or sex...
  70. ncbi request reprint Race and renal impairment in heart failure: mortality in blacks versus whites
    Grace L Smith
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
    Circulation 111:1270-7. 2005
    ..We sought to determine in HF patients the 1-year mortality risks associated with elevated creatinine and impaired estimated glomerular filtration rate (eGFR) and to quantify racial differences in mortality...
  71. ncbi request reprint Sex-based differences in the effect of digoxin for the treatment of heart failure
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale New Haven Hospital, New Haven, Conn, USA
    N Engl J Med 347:1403-11. 2002
    ..Even though the epidemiologic features, causes, and prognosis of heart failure vary between men and women, sex-based differences in the effect of digoxin were not evaluated...
  72. pmc Regional variations in racial differences in the treatment of elderly patients hospitalized with acute myocardial infarction
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med 117:811-22. 2004
    ..We sought to determine whether racial differences in myocardial infarction treatment vary by U.S. census region...
  73. ncbi request reprint Racial and ethnic differences in time to acute reperfusion therapy for patients hospitalized with myocardial infarction
    Elizabeth H Bradley
    Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    JAMA 292:1563-72. 2004
    ....
  74. ncbi request reprint Age, functional capacity, and health-related quality of life in patients with heart failure
    Frederick A Masoudi
    Department of Medicine, Denver Health Medical Center, Colorado 80204, USA
    J Card Fail 10:368-73. 2004
    ..We compared the relationship between functional limitation and HRQL between older and younger patients with heart failure...
  75. ncbi request reprint Cardiogenic shock complicating acute myocardial infarction in elderly patients: does admission to a tertiary center improve survival?
    Alan K Berger
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, and Yale New Haven Hospital Center for Outcomes Research and Evaluation, New Haven, CT 06520 8025, USA
    Am Heart J 143:768-76. 2002
    ..We sought to determine whether access to cardiovascular resources at the admitting hospital influenced the prognosis of patients with acute myocardial infarction complicated by cardiogenic shock...
  76. ncbi request reprint Gender differences in recovery after coronary artery bypass surgery
    Viola Vaccarino
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    J Am Coll Cardiol 41:307-14. 2003
    ..This study was designed to examine whether female gender is associated with poorer recovery after coronary artery bypass graft (CABG) surgery...
  77. ncbi request reprint Participation in cancer clinical trials: race-, sex-, and age-based disparities
    Vivek H Murthy
    Section of General Internal Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
    JAMA 291:2720-6. 2004
    ..Despite the importance of diversity of cancer trial participants with regard to race, ethnicity, age, and sex, there is little recent information about the representation of these groups in clinical trials...
  78. pmc From adversary to partner: have quality improvement organizations made the transition?
    Elizabeth H Bradley
    Department of Epidemiology and Public Health, Yale School of Medicine, 60 College Street, New Haven, CT 06520 8034, USA
    Health Serv Res 40:459-76. 2005
    ....
  79. ncbi request reprint Regional variation in the treatment and outcomes of myocardial infarction: investigating New England's advantage
    Harlan M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    Am Heart J 146:242-9. 2003
    ....
  80. pmc Association of door-to-balloon time and mortality in patients > or =65 years with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
    Saif S Rathore
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Cardiol 104:1198-203. 2009
    ....
  81. ncbi request reprint Validity of a simple ST-elevation acute myocardial infarction risk index: are randomized trial prognostic estimates generalizable to elderly patients?
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn, USA
    Circulation 107:811-6. 2003
    ..A simple risk-stratification index for patients with ST-segment elevation myocardial infarction derived from an RCT population was recently proposed, but it has not been validated in a community-based cohort...
  82. ncbi request reprint What are hospitals doing to increase beta-blocker use?
    Elizabeth H Bradley
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    Jt Comm J Qual Saf 29:409-15. 2003
    ..Despite the many proposed methods for improving quality, little is known about which methods are being applied in practice across the United States or their perceived effectiveness...
  83. ncbi request reprint Aspirin, beta-blocker, and angiotensin-converting enzyme inhibitor therapy in patients with end-stage renal disease and an acute myocardial infarction
    Alan K Berger
    Section of Cardiovascular Medicine, Department of Medicine, Minneapolis, Minnesota, USA
    J Am Coll Cardiol 42:201-8. 2003
    ..We sought to examine the use and impact of standard medical therapies in patients with end-stage renal disease (ESRD) faced with an acute myocardial infarction (AMI)...
  84. pmc Impact of delay in door-to-needle time on mortality in patients with ST-segment elevation myocardial infarction
    Robert L McNamara
    Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA
    Am J Cardiol 100:1227-32. 2007
    ..87, respectively; p for trend <0.001). In conclusion, timely administration of fibrinolytic therapy continues to significantly impact on mortality in the modern era, particularly in patients presenting early after symptom onset...
  85. ncbi request reprint JCAHO accreditation and quality of care for acute myocardial infarction
    Jersey Chen
    Yale University School of Medicine, USA
    Health Aff (Millwood) 22:243-54. 2003
    ..These findings support current efforts to incorporate quality of care in accreditation decisions...
  86. ncbi request reprint Metformin and thiazolidinedione use in Medicare patients with heart failure
    Frederick A Masoudi
    Division of Cardiology, Department of Medicine, Denver Health Medical Center, Colorado, USA
    JAMA 290:81-5. 2003
    ..Little is known about patterns of use of these antihyperglycemic drugs in diabetic patients with heart failure...
  87. doi request reprint Attitudes, training experiences, and professional expectations of US general surgery residents: a national survey
    Heather Yeo
    Division of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA
    JAMA 302:1301-8. 2009
    ..Despite the importance of resident perspectives in designing effective responses to these pressures, understanding of residents' views is limited...
  88. ncbi request reprint Worsening renal function: what is a clinically meaningful change in creatinine during hospitalization with heart failure?
    Grace L Smith
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Card Fail 9:13-25. 2003
    ..Prior studies define worsening renal function using various creatinine elevations, but the relative value of definitions is unknown...
  89. ncbi request reprint National patterns of use and effectiveness of angiotensin-converting enzyme inhibitors in older patients with heart failure and left ventricular systolic dysfunction
    Frederick A Masoudi
    Department of Medicine, Denver Health Medical Center, Denver, Colo 80204, USA
    Circulation 110:724-31. 2004
    ..Our objectives were to assess the correlates of ACE inhibitor use and the relationship between ACE inhibitor prescription and mortality in older patients with heart failure...
  90. ncbi request reprint "America's Best Hospitals" in the treatment of acute myocardial infarction
    Oliver J Wang
    Department of Medicine, Yale University School of Medicine, 333 Cedar St, PO Box 208088, New Haven, CT 06520, USA
    Arch Intern Med 167:1345-51. 2007
    ....
  91. ncbi request reprint Adoption of spironolactone therapy for older patients with heart failure and left ventricular systolic dysfunction in the United States, 1998-2001
    Frederick A Masoudi
    Division of Cardiology, Department of Medicine, Denver Health Medical Center, Denver, CO 80204, USA
    Circulation 112:39-47. 2005
    ..We studied the adoption of spironolactone therapy after publication of the Randomized Aldactone Evaluation Study (RALES) in national cohorts of older patients hospitalized for heart failure...
  92. ncbi request reprint Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study
    Frederick A Masoudi
    Department of Medicine, Division of Cardiology MC 0960, Denver Health Medical Center, 777 Bannock St, Denver, CO 80204, USA
    Circulation 111:583-90. 2005
    ..Whether this results in adverse outcomes is unknown...
  93. ncbi request reprint Patients with depressive symptoms have lower health status benefits after coronary artery bypass surgery
    Susmita Mallik
    Department of Medicine, Division of General Medicine, Emory University School of Medicine, Room 473, Faculty Office Bldg, 49 Jesse Hill Jr Drive, Atlanta, GA 30303, USA
    Circulation 111:271-7. 2005
    ..Depression is an established independent prognostic factor for mortality, readmission, and cardiac events after CABG surgery. However, limited data exist on whether depression influences functional outcomes after CABG...
  94. ncbi request reprint The obesity paradox: body mass index and outcomes in patients with heart failure
    Jeptha P Curtis
    Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Arch Intern Med 165:55-61. 2005
    ..We sought to examine the association of body mass index (BMI) and outcomes in stable outpatients with heart failure (HF)...
  95. ncbi request reprint Cardiac outcomes after myocardial infarction in elderly patients with diabetes mellitus
    Deborah Chyun
    Yale University, New Haven, Conn, USA
    Am J Crit Care 11:504-19. 2002
    ....
  96. ncbi request reprint Evaluation of a consumer-oriented internet health care report card: the risk of quality ratings based on mortality data
    Harlan M Krumholz
    Yale University School of Medicine, 333 Cedar St, PO Box 208025, New Haven, CT 06520 8025, USA
    JAMA 287:1277-87. 2002
    ..However, the ability of these ratings to discriminate between hospitals is not known...
  97. ncbi request reprint A randomized outpatient trial of a decision-support information technology tool
    Michael Apkon
    Yale New Haven Health, Yale University School of Medicine, New Haven, Conn, USA
    Arch Intern Med 165:2388-94. 2005
    ..Congress mandated the evaluation of Problem-Knowledge Couplers (PKC Corp, Burlington, Vt), a decision-support tool proposed for the Department of Defense's new health information network...
  98. ncbi request reprint Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction
    Dennis T Ko
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520 8025, USA
    JAMA 288:351-7. 2002
    ..Reluctance to prescribe these agents may derive from concerns about their association with symptoms of depression, fatigue, and sexual dysfunction...
  99. ncbi request reprint Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: implications for patients with and without recognized diabetes
    Mikhail Kosiborod
    Section of Cardiovascular Medicine, Yale University School of Medicine, 333 Cedar St, PO Box 208088, New Haven, CT 06520 8088, USA
    Circulation 111:3078-86. 2005
    ..The relationship between admission glucose levels and outcomes in older diabetic and nondiabetic patients with acute myocardial infarction is not well defined...
  100. ncbi request reprint Effect of door-to-balloon time on mortality in patients with ST-segment elevation myocardial infarction
    Robert L McNamara
    Department of Medicine, Section of Cardiovascular Medicine, Seattle, Washington, USA
    J Am Coll Cardiol 47:2180-6. 2006
    ..We sought to determine the effect of door-to-balloon time on mortality for patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI)...
  101. ncbi request reprint beta-Blockers in heart failure: clinical applications
    Michael H Farrell
    Yale University School of Medicine, 333 Cedar St, PO Box 208025, New Haven, CT 06520 8025, USA
    JAMA 287:890-7. 2002
    ....

Research Grants14

  1. Young Women With Acute Myocardial Infarction
    Harlan Krumholz; Fiscal Year: 2007
    ..We propose to conduct the largest, most comprehensive study of young women with heart attacks to identify the key determinants of their recovery and discover knowledge that will assist us in improving their care. ..
  2. Telemonitoring to improve heart failure outcomes
    Harlan Krumholz; Fiscal Year: 2007
    ..abstract_text> ..
  3. Strategies to reduce time to reperfusion therapy for MI
    Harlan Krumholz; Fiscal Year: 2005
    ..Data generated from these studies will guide efforts by clinicians, administrators, researchers, and policy makers to decrease time to reperfusion therapy for patients with STEMI. ..
  4. HOSPITAL PERFORMANCE & BETA-BLOCKER USE AFTER AMI
    Harlan Krumholz; Fiscal Year: 2001
    ..abstract_text> ..
  5. Young Women With Acute Myocardial Infarction
    HARLAN MARC KRUMHOLZ; Fiscal Year: 2010
    ..We propose to conduct the largest, most comprehensive study of young women with heart attacks to identify the key determinants of their recovery and discover knowledge that will assist us in improving their care. ..