Mira Krendel

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Myosins: tails (and heads) of functional diversity
    Mira Krendel
    Department of Molecular Biology, Yale University, New Haven, CN, USA
    Physiology (Bethesda) 20:239-51. 2005
  2. pmc Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis
    Mira Krendel
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA
    FEBS Lett 581:644-50. 2007
  3. ncbi Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
    Mira Krendel
    Department of Immunology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Nat Cell Biol 4:294-301. 2002
  4. ncbi p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor
    Frank T Zenke
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    J Biol Chem 279:18392-400. 2004

Collaborators

  • Emily K Osterweil
  • Frank T Zenke
  • Gary M Bokoch
  • Celine DerMardirossian
  • Benjamin P Bohl
  • Charles C King

Detail Information

Publications4

  1. ncbi Myosins: tails (and heads) of functional diversity
    Mira Krendel
    Department of Molecular Biology, Yale University, New Haven, CN, USA
    Physiology (Bethesda) 20:239-51. 2005
    ..In this review, recent insights into the remarkable diversity in the mechanochemical and functional properties associated with this family of molecular motors are discussed...
  2. pmc Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis
    Mira Krendel
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA
    FEBS Lett 581:644-50. 2007
    ..Expression of Myo1E tail, which acts in a dominant-negative manner, inhibits endocytosis of transferrin. Our findings suggest that myosin 1E may contribute to receptor-mediated endocytosis...
  3. ncbi Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
    Mira Krendel
    Department of Immunology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Nat Cell Biol 4:294-301. 2002
    ..Furthermore, these effects are inhibited by dominant-negative versions of GEF-H1. Thus, GEF-H1 links changes in microtubule integrity to Rho-dependent regulation of the actin cytoskeleton...
  4. ncbi p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor
    Frank T Zenke
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    J Biol Chem 279:18392-400. 2004
    ..Phosphorylation of GEF-H1 by PAK may be involved in regulation of GEF-H1 activity and may serve to coordinate Rho-, Rac-, and Cdc42-mediated signaling pathways...