Christine J Ko

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi request reprint Squamous cell carcinomas with single cell infiltration: a potential diagnostic pitfall and the utility of MNF116 and p63
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 35:353-7. 2008
  2. doi request reprint Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    Int J Dermatol 50:1480-5. 2011
  3. doi request reprint Keratoacanthoma: clinical and histopathologic features of regression
    Christine J Ko
    Yale University School of Medicine, New Haven, Connecticut, USA
    J Am Acad Dermatol 67:1008-12. 2012
  4. ncbi request reprint Hypertrophic lupus erythematosus: the diagnostic utility of CD123 staining
    Christine J Ko
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 38:889-92. 2011
  5. ncbi request reprint Melanocytic nevi with features of Spitz nevi and Clark's/dysplastic nevi ("Spark's" nevi)
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
    J Cutan Pathol 36:1063-8. 2009
  6. doi request reprint Adenosquamous carcinoma: a report of nine cases with p63 and cytokeratin 5/6 staining
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 36:448-52. 2009
  7. doi request reprint Clear (pale) cell acanthosis as an incidental finding
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
    J Cutan Pathol 36:573-7. 2009
  8. ncbi request reprint Fibrillar IgA deposition in dermatitis herpetiformis--an underreported pattern with potential clinical significance
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 37:475-7. 2010
  9. ncbi request reprint Actinic keratosis: facts and controversies
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    Clin Dermatol 28:249-53. 2010
  10. ncbi request reprint Keratoacanthoma: facts and controversies
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    Clin Dermatol 28:254-61. 2010

Collaborators

Detail Information

Publications32

  1. doi request reprint Squamous cell carcinomas with single cell infiltration: a potential diagnostic pitfall and the utility of MNF116 and p63
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 35:353-7. 2008
    ..CK MNF116 and p63 were useful in identifying each of these neoplasms. This single--cell pattern of SCC can easily be misdiagnosed, and CK MNF116 and/or p63 are diagnostically helpful in recognizing it...
  2. doi request reprint Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    Int J Dermatol 50:1480-5. 2011
    ..It is helpful for dermatologists to associate acantholysis with PRP in the correct clinical setting...
  3. doi request reprint Keratoacanthoma: clinical and histopathologic features of regression
    Christine J Ko
    Yale University School of Medicine, New Haven, Connecticut, USA
    J Am Acad Dermatol 67:1008-12. 2012
    ..The clinical and histopathologic features of regressing keratoacanthomas have not been adequately described in the literature...
  4. ncbi request reprint Hypertrophic lupus erythematosus: the diagnostic utility of CD123 staining
    Christine J Ko
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 38:889-92. 2011
    ..The pattern of CD123 staining can be a useful feature to distinguish hypertrophic LE from SCC and hypertrophic AK...
  5. ncbi request reprint Melanocytic nevi with features of Spitz nevi and Clark's/dysplastic nevi ("Spark's" nevi)
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
    J Cutan Pathol 36:1063-8. 2009
    ..Nevi with cytologic characteristics of Spitz nevus and architectural features of Clark's/dysplastic nevus are not well recognized in the literature...
  6. doi request reprint Adenosquamous carcinoma: a report of nine cases with p63 and cytokeratin 5/6 staining
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 36:448-52. 2009
    ..Six tumors stained focally in luminal areas with cytokeratin 7. Recognition of adenosquamous carcinoma is important for appropriate therapy, and stains for p63 and cytokeratin 5/6 may be helpful in ruling out metastatic adenocarcinoma...
  7. doi request reprint Clear (pale) cell acanthosis as an incidental finding
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
    J Cutan Pathol 36:573-7. 2009
    ..Two cases of incidental minute foci of clear (pale) cell acanthosis are described and put into the broader context of other epidermal histologic reaction patterns...
  8. ncbi request reprint Fibrillar IgA deposition in dermatitis herpetiformis--an underreported pattern with potential clinical significance
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 37:475-7. 2010
    ..Dermatitis herpetiformis may have a fibrillar rather than granular pattern of IgA deposition on direct immunofluorescent microscopy, and patients with this pattern of immunoglobulin deposition may lack circulating autoantibodies...
  9. ncbi request reprint Actinic keratosis: facts and controversies
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    Clin Dermatol 28:249-53. 2010
    ..Treatment of all actinic keratoses is advocated because preliminary evidence indicates that actinic keratoses may progress to squamous cell carcinomas. Some also consider actinic keratoses equivalent to squamous cell carcinoma...
  10. ncbi request reprint Keratoacanthoma: facts and controversies
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    Clin Dermatol 28:254-61. 2010
    ..It currently remains unclear how the keratoacanthoma relates to squamous cell carcinoma, and continued investigation is necessary...
  11. ncbi request reprint Muir-Torre syndrome: Facts and controversies
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
    Clin Dermatol 28:324-9. 2010
    ..The definition, potential clues, the role of ancillary testing (microsatellite, immunohistochemical, and genetic), and screening recommendations are reviewed...
  12. doi request reprint "Clark/dysplastic" nevi with florid fibroplasia associated with pseudomelanomatous features
    Christine J Ko
    Department of Dermatology and Pathology, Yale University School of Medicine, New Haven, CT, USA
    J Am Acad Dermatol 64:346-51. 2011
    ..Melanocytic nevi may exhibit histologic features in common with cutaneous melanoma, creating diagnostic difficulties...
  13. doi request reprint Acantholytic dyskeratotic acanthoma: a variant of a benign keratosis
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    J Cutan Pathol 35:298-301. 2008
    ..There was a slight female predominance. Confluent acantholysis and dyskeratosis is a histologic pattern that may present as a solitary keratosis...
  14. ncbi request reprint The new World Health Organization-European Organization for Research and Treatment of Cancer classification of cutaneous lymphomas
    Christine J Ko
    Yale University, 15 York Street, LMP 5031, New Haven, CT 06510, USA
    Adv Dermatol 22:259-77. 2006
    ..Much remains to be elucidated about cutaneous lymphomas, but understanding of the major entities within the new classification is an important first step in understanding these diverse diseases...
  15. ncbi request reprint Changes of epidermodysplasia verruciformis in benign skin lesions: the EV acanthoma
    Christine J Ko
    Yale New Haven Hospital, New Haven, CT, USA
    J Cutan Pathol 34:44-8. 2007
    ..EV changes and EV-HPV can be found incidentally on biopsy in the absence of clinical EV; when such changes are the major histopathological finding in an isolated skin lesion, the lesion should be termed an EV acanthoma...
  16. ncbi request reprint Langerhans cells in squamous cell carcinoma vs. pseudoepitheliomatous hyperplasia of the skin
    Anjela Galan
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06510, USA
    J Cutan Pathol 34:950-2. 2007
    ..SCCs of the head and neck similarly have decreased E-cadherin expression, but E-cadherin expression is preserved in PEH. We hypothesized that PEH of the skin would have an increased number of Langerhans cells compared with SCC...
  17. doi request reprint Detecting HPV in cutaneous lesions using anti-HPV antibody immunohistochemistry
    Jade Wititsuwannakul
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    Am J Dermatopathol 35:327-31. 2013
    ....
  18. ncbi request reprint Bcl-2-positive epidermal dendritic cells in inverted follicular keratoses but not squamous cell carcinomas or seborrheic keratoses
    Christine J Ko
    Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA, USA
    J Cutan Pathol 33:498-501. 2006
    ..The purpose of this study was twofold; firstly, to support that these dendritic cells are Langerhans cells and secondly, to contrast the epidermal dendritic cells in IFKs, squamous cell carcinomas (SCCs), and SKs...
  19. doi request reprint Dilated lymphatic vessels in tufted angioma: a potential source of diagnostic confusion
    Mona Sadeghpour
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Dermatopathol 34:400-3. 2012
    ..Accurate diagnosis of TA has important clinical implications given its occasional association with Kasabach-Merritt phenomenon, and the presence of lymphangioma-like vessels in biopsies of vascular lesions is entirely compatible with TA...
  20. doi request reprint Cutaneous squamous cell carcinomas of the lower extremity: a distinct subset of squamous cell carcinomas
    Changhyun Kim
    Department of Dermatology, Yale University, New Haven, Connecticut
    J Am Acad Dermatol 70:70-4. 2014
    ..Some patients develop a disproportionate number of cutaneous squamous cell carcinomas (SCCs) on their lower extremity (LE)...
  21. doi request reprint Recurrent cutaneous toxic erythema induced by gemcitabine in a patient with pancreatic cancer
    Jia Li
    Department of Medical Oncology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cutan Ocul Toxicol 28:144-8. 2009
    ..We report a case of recurrent cutaneous toxicity during adjuvant chemotherapy with gemcitabine after complete resection of pancreatic adenocarcinoma...
  22. ncbi request reprint Hidradenocarcinoma: a histological and immunohistochemical study
    Christine J Ko
    Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA, USA
    J Cutan Pathol 33:726-30. 2006
    ..In making the diagnosis of hidradenocarcinoma, it may be unnecessary to separate hidradenocarcinoma into eccrine and apocrine categories, and although Ki67 and p53 may be helpful, histological parameters remain paramount...
  23. ncbi request reprint Two cases of hemihyperplasia-multiple lipomatosis syndrome and review of asymmetric hemihyperplasia syndromes
    Brittany G Craiglow
    Department of Dermatology, School of Medicine, Yale University, New Haven, Connecticut
    Pediatr Dermatol 31:507-10. 2014
    ..We also provide a brief review of asymmetric overgrowth syndromes, which have overlapping yet distinct clinical manifestations. ..
  24. ncbi request reprint Punctate pemphigus: an underreported direct immunofluorescence pattern
    Christine J Ko
    Dermatology and Pathology, Yale University, New Haven, CT, USA
    J Cutan Pathol 41:293-6. 2014
    ..This series highlights the punctate or dot-like pattern of intercellular IgG deposition in DIF studies of pemphigus, reviews potential mechanisms and calls attention to this potentially under-recognized phenomenon. ..
  25. doi request reprint Neutrophilic dermatosis after azathioprine exposure
    Nika Cyrus
    Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510, USA
    JAMA Dermatol 149:592-7. 2013
    ..Histologically, both azathioprine hypersensitivity syndrome and Sweet syndrome are rich in neutrophils...
  26. doi request reprint Perifollicular fibroma in Birt-Hogg-Dubé syndrome: an association revisited
    Marianna Shvartsbeyn
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Cutan Pathol 39:675-9. 2012
    ..Although some consider perifollicular fibroma to be a variant of angiofibroma, the specific histopathologic findings of perifollicular fibroma are uncommon...
  27. ncbi request reprint Pediculosis
    Christine J Ko
    Department of Dermatology, University of California at Irvine, USA
    J Am Acad Dermatol 50:1-12; quiz 13-4. 2004
    ..Major types of resistance include knock-down resistance, glutathione-S-transferase-based resistance, and monooxygenase-based resistance. Research is needed to identify new effective treatments...
  28. ncbi request reprint Syringomatous carcinoma in a young patient treated with Mohs micrographic surgery
    Jenny C Hu
    Division of Dermatology, David Geffen School of Medicine, University of California, Los Angeles 90095, USA
    Cutis 77:19-24; quiz 37-8. 2006
    ..using Mohs micrographic surgery (MS). This case demonstrates the importance of differentiating SC from other benign or malignant entities, the value of a prompt diagnosis of SC, and the effective treatment of SC with MMS...
  29. ncbi request reprint Comparison of benign keratoses using p53, bcl-1, and bcl-2
    Christine J Ko
    Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA
    J Cutan Pathol 32:356-9. 2005
    ..Keratinocyte bcl-2 staining was significantly higher in SKs compared with the other two keratoses. Bcl-2 may be increased in SKs as an anti-apoptotic mechanism...
  30. ncbi request reprint Scalp paraffinoma underlying squamous cell carcinoma
    Christine J Ko
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles 90095, USA
    Arch Pathol Lab Med 128:1171-2. 2004
    ..Carcinomas have been reported in association with penile and breast paraffinomas, but we are unaware of any reports of squamous cell carcinoma arising over a scalp paraffinoma...
  31. ncbi request reprint Unguioblastoma and unguioblastic fibroma--an expanded spectrum of onychomatricoma
    Christine J Ko
    Dermatopathology Laboratory, University of California, Irvine, CA, USA
    J Cutan Pathol 31:307-11. 2004
    ..The term "atypical unguioblastic fibroma" is used to describe a third rare neoplasm, in which the cellular stroma shows nuclear pleomorphism and atypia with an increase of mitotic activity...
  32. ncbi request reprint Calcospherules associated with juvenile hyaline fibromatosis
    Christine J Ko
    Department of Dermatology and Dermatopathology Laboratory, University of California, Irvine, USA
    Am J Dermatopathol 25:53-6. 2003
    ..A case of juvenile hyaline fibromatosis with typical skin tumors that on biopsy exhibited basophilic calcospherules is presented. Although noted in a single case, these structures may be a novel, yet helpful, diagnostic marker...