Research Topics
| J P KniselySummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Image registration and calculation of a biologically effective dose for multisession radiosurgical treatments. Technical noteJ P Knisely
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520 8040, USA
J Neurosurg 93:208-18. 2000..It may be useful for a future update of the GammaPlan treatment planning software to generate effective single-session dose distributions for such cases...- Where observation is concerned, chance favours only the prepared mindJonathan Knisely
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
Lancet Oncol 9:502. 2008 
A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118)Jonathan P S Knisely
Department of Therapeutic Radiology, Yale University School of Medicine and Yale Cancer Center, New Haven, CT 06520 8040, USA
Int J Radiat Oncol Biol Phys 71:79-86. 2008..To compare whole-brain radiation therapy (WBRT) with WBRT combined with thalidomide for patients with brain metastases not amenable to resection or radiosurgery...- Radiosurgery alone for 5 or more brain metastases: expert opinion surveyJonathan P S Knisely
Department of Therapeutic Radiology, Yale University School of Medicine and Yale Cancer Center, New Haven, Connecticut 06520 8040, USA
J Neurosurg 113:84-9. 2010..A survey was conducted at 2 radiosurgery meetings to determine which factors SRS practitioners emphasize in recommending SRS alone, and what physician characteristics are associated with recommending SRS alone for ≥ 5 metastases... - Less common indications for stereotactic radiosurgery or fractionated radiotherapy for patients with benign brain tumorsJonathan P S Knisely
Department of Therapeutic Radiology, Yale University School of Medicine, Hunter Radiation Therapy Center, PO Box 208040, New Haven, CT 06520 8040, USA
Neurosurg Clin N Am 17:149-67, vii. 2006..Patients need to be apprised of all therapeutic options and to make their decisions with all information required to evaluate the risks and benefits. For benign brain tumors, these decisions may have consequences that last for decades... - Importance of hypoxia in the biology and treatment of brain tumorsJonathan P S Knisely
Department of Therapeutic Radiology, Yale University School of Medicine, P O Box 208040, New Haven, CT 06520 8040, USA
Neuroimaging Clin N Am 12:525-36. 2002..Several ongoing clinical trials are addressing other, hopefully better regimens; it will be interesting to see the results of these studies... - Automated 2D-3D registration of portal images and CT data using line-segment enhancementReshma Munbodh
Department of Electrical Engineering, Yale University, New Haven, Connecticut 06520, USA
Med Phys 35:4352-61. 2008..They also indicate that it is feasible to estimate all six transformation parameters from a 3D CT of the pelvis and a single portal image in the AP view... - 2D-3D registration for prostate radiation therapy based on a statistical model of transmission imagesReshma Munbodh
Department of Radiology, Weill Medical College of Cornell University, New York, New York 10021, USA
Med Phys 36:4555-68. 2009..We present a 2D-3D registration framework based on a statistical model of the intensity values in the two imaging modalities... - Comparison of an image registration technique based on normalized mutual information with a standard method utilizing implanted markers in the staged radiosurgical treatment of large arteriovenous malformationsJames E Bond
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520 8040, USA
Int J Radiat Oncol Biol Phys 57:1150-8. 2003.... 
Automated 2D-3D registration of a radiograph and a cone beam CT using line-segment enhancementReshma Munbodh
Department of Electrical Engineering, Yale University, New Haven, Connecticut 06520, USA
Med Phys 33:1398-411. 2006..This technique is theoretically applicable to other rigid bony structures such as the cranial vault or skull base and piecewise rigid structures such as the spine...- Long-term response to fractionated radiotherapy of presumed optic nerve sheath meningiomaRobert L Lesser
40 Temple Street Suite 5 B, New Haven, CT 06510, USA
Br J Ophthalmol 94:559-63. 2010..No major side effects from radiation were seen. CONCLUSIONS Vision, MRI and complication outcomes are favourable for using fractionated conformal radiotherapy for ONSM... - A method to implement full six-degree target shift corrections for rigid body in image-guided radiotherapyNing J Yue
Department of Therapeutic Radiology, Yale University School of Medicine, P O Box 208040, New Haven, Connecticut 06520 8040, USA
Med Phys 33:21-31. 2006..This method was applied to a head phantom study, and it was found that the target shift was fully corrected in treatment and excellent agreement was found in target dose coverage between the plan and the treatment... - A technique to re-establish dose distributions for previously treated brain cancer patients in external beam radiotherapyNing J Yue
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
Med Dosim 29:31-41. 2004..The method has been proven to be successful and robust... - Gamma Knife surgery for the treatment of melanoma metastases: the effect of intratumoral hemorrhage on survivalAndy J Redmond
Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520 8082, USA
J Neurosurg 109:99-105. 2008..In this study the authors investigated which patient- or treatment-specific factors influence survival of patients with melanoma brain metastases; they pay particular interest to pre- and post-GKS hemorrhage... - An update on the treatment of CNS metastases in small cell lung cancerWilliam A Castrucci
Department of Therapeutic Radiology, Yale University School of Medicine, Yale Cancer Center, New Haven, Connecticut 06520 8040, USA
Cancer J 14:138-46. 2008..This finding should significantly shift management practices for this aggressive disease for most patients... - The interactions of polarographic measurements of oxygen tension and histological grade in human gliomaBrian E Lally
Department of Therapeutic Radiology, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520-8040, USA
Cancer J 12:461-6. 2006.... - A dosimetric evaluation of conventional helmet field irradiation versus two-field intensity-modulated radiotherapy techniqueJames B Yu
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520 8040, USA
Int J Radiat Oncol Biol Phys 68:621-31. 2007..To compare dosimetric differences between conventional two-beam helmet field irradiation (external beam radiotherapy, EBRT) of the brain and a two-field intensity-modulated radiotherapy (IMRT) technique... - Prognostic factors for survival after stereotactic radiosurgery vary with the number of cerebral metastasesMichael L DiLuna
Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA
Cancer 109:135-45. 2007..Little is understood about the factors that influence survival in patients who undergo gamma-knife stereotactic radiosurgery (SRS) for brain metastases... - The role of postoperative radiation therapy (PORT) in the treatment of extrahepatic bile duct cancer: a surveillance, epidemiology, and end results (SEER) population-based investigationJames B Yu
Department of Therapeutic Radiology, Yale School of Medicine, HRT 133, 333 Cedar St, New Haven, CT 06520, USA
J Gastrointest Cancer 39:11-21. 2008..Extrahepatic bile duct cancers (EBDC) are aggressive cancers for which the importance of the use of postoperative radiation therapy (PORT) in potentially curative cases remains the subject of clinical investigation... - Prospective evaluation of quality of life and neurocognitive effects in patients with multiple brain metastases receiving whole-brain radiotherapy with or without thalidomide on Radiation Therapy Oncology Group (RTOG) trial 0118Benjamin W Corn
Department of Radiation Oncology, Tel Aviv Medical Center, Tel Aviv, Israel
Int J Radiat Oncol Biol Phys 71:71-8. 2008..This secondary analysis of 156 patients examined neurocognitive and quality of life (QOL) outcomes... - Surgical treatment of esophageal cancerJonathan P S Knisely
N Engl J Med 348:1177-9; author reply 1177-9. 2003 - Mature survival results with preoperative cisplatin, protracted infusion 5-fluorouracil, and 44-Gy radiotherapy for esophageal cancerLawrence Kleinberg
Sidney Kimmel Oncology Center at Johns Hopkins, Baltimore, MD 21231, USA
Int J Radiat Oncol Biol Phys 56:328-34. 2003..To assess the long-term survival results after cisplatin, protracted infusion 5-fluorouracil, and concurrent radiotherapy (RT) followed by surgical resection of esophageal cancer... - Carbamylated erythropoietin reduces radiosurgically-induced brain injurySerhat Erbayraktar
, Izmir, Turkey
Mol Med 12:74-80. 2006..These findings further extend the kinds of injury for which administration of a tissue-protective cytokine provides benefit... - Phase II, parallel-design study of preoperative combined modality therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinomaElisabeth I Heath
Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
Invest New Drugs 24:135-40. 2006..The objectives of the trial were to determine pathologic complete response rate (pCR), overall response rate, progression-free survival, pattern of disease relapse, and two-year and overall survival...