Research Topics
| A KlinSummaryAffiliation: Yale University Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
The enactive mind, or from actions to cognition: lessons from autismAmi Klin
Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA
Philos Trans R Soc Lond B Biol Sci 358:345-60. 2003....
Attributing social and physical meaning to ambiguous visual displays in individuals with higher-functioning autism spectrum disordersAmi Klin
Yale Child Study Center, New Haven, CT, USA
Brain Cogn 61:40-53. 2006....- Autism in a 15-month-old childAmi Klin
Yale Child Study Center, P.O. Box 207900, New Haven, CT 06520, USA
Am J Psychiatry 161:1981-8. 2004 - Social and communication abilities and disabilities in higher functioning individuals with autism spectrum disorders: the Vineland and the ADOSAmi Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
J Autism Dev Disord 37:748-59. 2007..Positive relationships were found between IQ and Vineland Communication. Results stress the need for longitudinal studies on ability and disability in ASD and emphasize the importance of adaptive skills intervention... - Two-year-olds with autism orient to non-social contingencies rather than biological motionAmi Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06519 1124, USA
Nature 459:257-61. 2009..This observation has far-reaching implications for understanding the altered neurodevelopmental trajectory of brain specialization in autism... - Asperger syndrome: an updateAmi Klin
Child Psychology and Psychiatry Yale Child Study Center, New Haven, CT 06520, USA
Rev Bras Psiquiatr 25:103-9. 2003.... - Three diagnostic approaches to Asperger syndrome: implications for researchAmi Klin
Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
J Autism Dev Disord 35:221-34. 2005..Differences across the three nosologic systems were examined in terms of diagnostic assignment, IQ profiles, comorbid symptoms, and familial aggregation of social and other psychiatric symptoms... - Asperger syndrome: diagnosis and external validityAmi Klin
Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
Child Adolesc Psychiatr Clin N Am 12:1-13, v. 2003.... - Attributing social meaning to ambiguous visual stimuli in higher-functioning autism and Asperger syndrome: The Social Attribution TaskA Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
J Child Psychol Psychiatry 41:831-46. 2000..When provided with more explicit verbal information on the nature of the cartoon, individuals with AS improved their performance slightly more than those with autism, but not significantly so... - Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autismAmi Klin
Yale Child Study Center, Yale University, 230 S Frontage Rd, New Haven, CT 06520, USA
Arch Gen Psychiatry 59:809-16. 2002..Enhanced ecological validity was intended to maximize between-group effect sizes and assess the predictive utility of experimental variables relative to outcome measures of social competence... - A normed study of face recognition in autism and related disordersA Klin
Yale Child Study Center, New Haven Connecticut 06520, USA
J Autism Dev Disord 29:499-508. 1999..Contrary to our expectation, children with PDDNOS did not show face recognition deficits... - Defining and quantifying the social phenotype in autismAmi Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Psychiatry 159:895-908. 2002..Genetic and neurofunctional research in autism has highlighted the need for improved characterization of the core social disorder defining the broad spectrum of syndrome manifestations... 
Embracing the challenge of bold theories of autismAmi Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
Br J Psychol 100:29-32. 2009..This article is a commentary on 'Fetal testosterone and autistic traits' (Auyeung et al., 2009)...- Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndromeR T Schultz
Child Study Center, Yale University, New Haven, Conn 06520 7900, USA
Arch Gen Psychiatry 57:331-40. 2000..Therefore, it is of considerable interest that individuals with autism and related conditions have selective deficits in face recognition (sparing nonface object recognition)... - Verbal bias in recognition of facial emotions in children with Asperger syndromeJ B Grossman
Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
J Child Psychol Psychiatry 41:369-79. 2000..e., words over faces). Thus, children with AS may be utilizing compensatory strategies, such as verbal mediation, to process facial expressions of emotion... - Higher-functioning pervasive developmental disorders: rates and patterns of psychotropic drug useA Martin
Child Study Center, Yale University School of Medicine, New Haven, CT, USA
J Am Acad Child Adolesc Psychiatry 38:923-31. 1999..To explore the frequency, characteristics, and associated target symptoms of psychotropic drug use among subjects with higher-functioning pervasive developmental disorders (HFPDDs)... - Educational placements and service use patterns of individuals with autism spectrum disordersSUSAN WILLIAMS WHITE
Virginia Treatment Center for Children, School of Medicine, Virginia Commonwealth University, 515 North 10th Street, Richmond, Virginia 23298, USA
J Autism Dev Disord 37:1403-12. 2007..Findings highlight the emphasis placed on certain child characteristics (e.g., cognitive ability), with far less emphasis on other areas (e.g., degree of social deficit), in educational placement and service provision... - Asperger's syndromeJames McPartland
Yale Child Study Center, New Haven, CT 06520, USA
Adolesc Med Clin 17:771-88; abstract xiii. 2006..Existing research is reviewed within the areas of epidemiology, medical/neurobiologic factors, genetics, and outcome, and future directions for research are recommended... - Studying the emergence of autism spectrum disorders in high-risk infants: methodological and practical issuesLonnie Zwaigenbaum
Department of Paediatrics, McMaster Children s Hospital at McMaster University, Hamilton, Ontario, Canada
J Autism Dev Disord 37:466-80. 2007..We suggest possible design and implementation strategies to address these various challenges, based on current research efforts in the field and previous studies involving high-risk populations... - Brief report: relations between prosodic performance and communication and socialization ratings in high functioning speakers with autism spectrum disordersRhea Paul
Yale Child Study Center, New Haven, CT 06520 7900, USA
J Autism Dev Disord 35:861-9. 2005..They suggest the need for careful assessment of inappropriate prosody and voice features in speakers with ASD, and for effective intervention programs aimed at reducing the stigmatization of individuals with these conditions... - Absence of preferential looking to the eyes of approaching adults predicts level of social disability in 2-year-old toddlers with autism spectrum disorderWarren Jones
Yale Child Study Center, Yale University School of Medicine, 230 S Frontage Rd, New Haven, CT 06520, USA
Arch Gen Psychiatry 65:946-54. 2008..For children with autism, however, diminished and aberrant eye contact is a lifelong hallmark of disability... - Brief report: social and communication abilities and disabilities in higher functioning individuals with autism and Asperger syndromeCeline A Saulnier
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
J Autism Dev Disord 37:788-93. 2007..No relationship was found between adaptive functioning and symptom severity... - Autism spectrum disorder in the second year: stability and change in syndrome expressionKatarzyna Chawarska
Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06511, USA
J Child Psychol Psychiatry 48:128-38. 2007.... - The modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disordersJamie M Kleinman
Department of Psychology, University of Connecticut, 406 Babbidge Rd, Storrs, CT 06269 1020, USA
J Autism Dev Disord 38:827-39. 2008..Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD... - Reliability of the ADI-R: multiple examiners evaluate a single caseDomenic V Cicchetti
Child Study Center, Yale University School of Medicine, New Haven, CT, USA
J Autism Dev Disord 38:764-70. 2008..62 and 0.68); and in fair agreement on 3% (82 - 84%, with K(w) between .40 and .47). For the remaining 10% of ADI-R items, examiners showed poor agreement (50-81% with K(w )between -.67 and .37)... - Parental recognition of developmental problems in toddlers with autism spectrum disordersKatarzyna Chawarska
Yale Child Study Center, Yale University School of Medicine, New Haven, CT, 06520, USA
J Autism Dev Disord 37:62-72. 2007..Later AOR was associated with poorer social-communicative and nonverbal cognitive functioning at 2 and 4. The findings are discussed in a context of identifying distinct developmental trajectories within the autism spectrum... - In the eye of the beholden: tracking developmental psychopathologyAmi Klin
J Am Acad Child Adolesc Psychiatry 47:362-3. 2008 - The structure of intelligence in children and adults with high functioning autismGerald Goldstein
VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania 15206, USA
Neuropsychology 22:301-12. 2008..Findings suggest similar organization of cognitive abilities in HFA, but with the possibility of underconnectivity or reduced communication among brain regions in autism... - Disruption of Contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndromeThomas Fernandez
Am J Hum Genet 82:1385. 2008 - Altered face scanning and impaired recognition of biological motion in a 15-month-old infant with autismAmi Klin
Yale Child Study Center, Yale University School of Medicine, USA
Dev Sci 11:40-6. 2008.... - Asperger's syndrome: a comparison of clinical diagnoses and those made according to the ICD-10 and DSM-IVMarc Woodbury-Smith
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
J Autism Dev Disord 35:235-40. 2005..It is suggested that this is due to limitations inherent in these criteria, and alternative conceptualizations are discussed... - Perception and production of prosody by speakers with autism spectrum disordersRhea Paul
Southern Connecticut State University, USA
J Autism Dev Disord 35:205-20. 2005..The implications of these findings for understanding prosodic deficits is speakers with autism spectrum disorders, and for future research in this area, are discussed... - Autism and pervasive developmental disordersFred R Volkmar
Child Study Center, Yale University, New Haven, CT 06520, USA
J Child Psychol Psychiatry 45:135-70. 2004..Significant challenges lie ahead in evaluating the growing number of treatments for autism and in integrating the results of research into treatment and educational settings... - Annotation: Hyperlexia: disability or superability?Elena L Grigorenko
Child Study Center, Yale University, New Haven, CT 06510, USA
J Child Psychol Psychiatry 44:1079-91. 2003..Hyperlexia is the phenomenon of spontaneous and precocious mastery of single-word reading that has been of interest to clinicians and researchers since the beginning of the last century... - Automatic attention cueing through eye movement in 2-year-old children with autismKatarzyna Chawarska
Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
Child Dev 74:1108-22. 2003..Cue-specific differences in performance related to the level of engagement and cue-processing time may suggest reliance on different underlying strategies for gaze processing in autism... - Concurrent validity and classification accuracy of the Leiter and Leiter-R in low-functioning children with autismKatherine D Tsatsanis
Yale University, Yale Child Study Center, USA
J Autism Dev Disord 33:23-30. 2003..However, because of changes in the design of the Leiter-R, there may be greater clinical success with the original Leiter for those children who are very low functioning and severely affected, particularly younger children... - The role of the fusiform face area in social cognition: implications for the pathobiology of autismRobert T Schultz
Child Study Center, Yale University School of Medicine, 230 S Frontage Road, New Haven, CT 06520 7900, USA
Philos Trans R Soc Lond B Biol Sci 358:415-27. 2003..From this perspective, the literature on hypoactivation of the FFA in autism may be interpreted as a reflection of a core social cognitive mechanism underlying the disorder... - Asperger syndromeAmi Klin
Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
Child Adolesc Psychiatr Clin N Am 12:xiii-xvi. 2003 - Genetics of childhood disorders: XLIII. Autism, part 2: neural foundationsRobert T Schultz
Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
J Am Acad Child Adolesc Psychiatry 41:1259-62. 2002 - A descriptive study of hyperlexia in a clinically referred sample of children with developmental delaysElena L Grigorenko
Department of Psychology, Child Study Center, Yale University, New Haven, CT 06520 8205, USA
J Autism Dev Disord 32:3-12. 2002..The range of IQ and other cognitive skills and the developmental outcomes of children with hyperlexia were comparable to those of children without hyperlexia... - Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndromeThomas Fernandez
Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Hum Genet 74:1286-93. 2004..Our results demonstrate the association of CNTN4 disruption with the 3p deletion syndrome phenotype and strongly suggest a causal relationship. These findings point to an important role for CNTN4 in normal and abnormal CNS development... - Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism networkSally Ozonoff
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA
J Autism Dev Disord 34:139-50. 2004.... - Adaptive behavior in autism and Pervasive Developmental Disorder-Not Otherwise Specified: microanalysis of scores on the Vineland Adaptive Behavior ScalesRhea Paul
Yale Child Study Center, PO Box 207900, New Haven, CT 06520 7900, USA
J Autism Dev Disord 34:223-8. 2004..Implications of these findings for both diagnosis and intervention with children with Autism Spectrum Disorders will be discussed... - When Asperger's syndrome and a nonverbal learning disability look alikeMartin T Stein
University of California San Diego, San Diego, California, USA
J Dev Behav Pediatr 25:190-5. 2004 - When Asperger's syndrome and a nonverbal learning disability look alikeMartin T Stein
University of California San Diego, San Diego, California, USA
J Dev Behav Pediatr 25:S59-64. 2004 - Deficits in social attribution ability in Prader-Willi syndromeKathleen Koenig
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
J Autism Dev Disord 34:573-82. 2004.... - Source memory in children with autism spectrum disordersAngela Garcia O'Shea
Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06510, USA
Dev Neuropsychol 27:337-60. 2005.... - Autism in infancy and early childhoodFred Volkmar
Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
Annu Rev Psychol 56:315-36. 2005..New approaches to screening have lowered the age of initial diagnosis; this presents new challenges for early intervention. Directions for future research are highlighted... - What's so special about Asperger Syndrome?Simon Baron-Cohen
Brain Cogn 61:1-4. 2006 - [Autism and the pervasive developmental disorders]Ami Klin
Rev Bras Psiquiatr 28:S1-2. 2006 - Reduced thalamic volume in high-functioning individuals with autismKatherine D Tsatsanis
Yale Child Study Center, Yale University, New Haven Connecticut 06520-7900, USA
Biol Psychiatry 53:121-9. 2003..CONCLUSION: The increase in thalamic volume with increase in TBV was not seen in autism, suggesting underdeveloped connections between cortical and subcortical regions and indicating a need to examine this structure further... - [Autism and Asperger syndrome: an overview]Ami Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
Rev Bras Psiquiatr 28:S3-11. 2006..This overview focuses on the history, nosology, and the clinical and associated features of the two most well-known pervasive developmental disorders - autism and Asperger syndrome... - Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disordersBetul Bakkaloglu
Program on Neurogenetics, Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Hum Genet 82:165-73. 2008.... - Disruption of neurexin 1 associated with autism spectrum disorderHyung Goo Kim
Molecular Neurogenetics Unit, Center for Human Genetic Research and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Am J Hum Genet 82:199-207. 2008....
Research Grants
- Eye-Tracking Studies of Social Visual Pursuit in AutismAmi Klin; Fiscal Year: 2006..The proposed R01 works synergistically with other ongoing eye-tracking research including studies of toddlers at risk of having autism and studies of monkeys with mesiofrontal-limbic ablations. ..
- Perception of Social and Physical Contingencies in Infants with ASDAmi Klin; Fiscal Year: 2010....
- The Ontogeny of Social Visual Engagement in Infants at Risk for AutismAmi Klin; Fiscal Year: 2009..Like the Committee's action items, this project emphasizes developmental markers and screening in infants, as well as neurodevelopmental processes, and is, therefore, highly relevant to public health. ..
- The Ontogeny of Social Visual Engagement in Infants at Risk for AutismAmi Klin; Fiscal Year: 2010..Like the Committee's action items, this project emphasizes developmental markers and screening in infants, as well as neurodevelopmental processes, and is, therefore, highly relevant to public health. ..