A Klin

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc The enactive mind, or from actions to cognition: lessons from autism
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA
    Philos Trans R Soc Lond B Biol Sci 358:345-60. 2003
  2. ncbi request reprint Attributing social and physical meaning to ambiguous visual displays in individuals with higher-functioning autism spectrum disorders
    Ami Klin
    Yale Child Study Center, New Haven, CT, USA
    Brain Cogn 61:40-53. 2006
  3. ncbi request reprint Autism in a 15-month-old child
    Ami Klin
    Yale Child Study Center, P O Box 207900, New Haven, CT 06520, USA
    Am J Psychiatry 161:1981-8. 2004
  4. ncbi request reprint Social and communication abilities and disabilities in higher functioning individuals with autism spectrum disorders: the Vineland and the ADOS
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 37:748-59. 2007
  5. pmc Two-year-olds with autism orient to non-social contingencies rather than biological motion
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06519 1124, USA
    Nature 459:257-61. 2009
  6. ncbi request reprint Asperger syndrome: an update
    Ami Klin
    Child Psychology and Psychiatry Yale Child Study Center, New Haven, CT 06520, USA
    Rev Bras Psiquiatr 25:103-9. 2003
  7. ncbi request reprint Three diagnostic approaches to Asperger syndrome: implications for research
    Ami Klin
    Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
    J Autism Dev Disord 35:221-34. 2005
  8. ncbi request reprint Asperger syndrome: diagnosis and external validity
    Ami Klin
    Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
    Child Adolesc Psychiatr Clin N Am 12:1-13, v. 2003
  9. ncbi request reprint Attributing social meaning to ambiguous visual stimuli in higher-functioning autism and Asperger syndrome: The Social Attribution Task
    A Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    J Child Psychol Psychiatry 41:831-46. 2000
  10. ncbi request reprint Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism
    Ami Klin
    Yale Child Study Center, Yale University, 230 S Frontage Rd, New Haven, CT 06520, USA
    Arch Gen Psychiatry 59:809-16. 2002

Collaborators

Detail Information

Publications54

  1. pmc The enactive mind, or from actions to cognition: lessons from autism
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA
    Philos Trans R Soc Lond B Biol Sci 358:345-60. 2003
    ....
  2. ncbi request reprint Attributing social and physical meaning to ambiguous visual displays in individuals with higher-functioning autism spectrum disorders
    Ami Klin
    Yale Child Study Center, New Haven, CT, USA
    Brain Cogn 61:40-53. 2006
    ....
  3. ncbi request reprint Autism in a 15-month-old child
    Ami Klin
    Yale Child Study Center, P O Box 207900, New Haven, CT 06520, USA
    Am J Psychiatry 161:1981-8. 2004
  4. ncbi request reprint Social and communication abilities and disabilities in higher functioning individuals with autism spectrum disorders: the Vineland and the ADOS
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 37:748-59. 2007
    ..Positive relationships were found between IQ and Vineland Communication. Results stress the need for longitudinal studies on ability and disability in ASD and emphasize the importance of adaptive skills intervention...
  5. pmc Two-year-olds with autism orient to non-social contingencies rather than biological motion
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06519 1124, USA
    Nature 459:257-61. 2009
    ..This observation has far-reaching implications for understanding the altered neurodevelopmental trajectory of brain specialization in autism...
  6. ncbi request reprint Asperger syndrome: an update
    Ami Klin
    Child Psychology and Psychiatry Yale Child Study Center, New Haven, CT 06520, USA
    Rev Bras Psiquiatr 25:103-9. 2003
    ....
  7. ncbi request reprint Three diagnostic approaches to Asperger syndrome: implications for research
    Ami Klin
    Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
    J Autism Dev Disord 35:221-34. 2005
    ..Differences across the three nosologic systems were examined in terms of diagnostic assignment, IQ profiles, comorbid symptoms, and familial aggregation of social and other psychiatric symptoms...
  8. ncbi request reprint Asperger syndrome: diagnosis and external validity
    Ami Klin
    Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
    Child Adolesc Psychiatr Clin N Am 12:1-13, v. 2003
    ....
  9. ncbi request reprint Attributing social meaning to ambiguous visual stimuli in higher-functioning autism and Asperger syndrome: The Social Attribution Task
    A Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    J Child Psychol Psychiatry 41:831-46. 2000
    ..When provided with more explicit verbal information on the nature of the cartoon, individuals with AS improved their performance slightly more than those with autism, but not significantly so...
  10. ncbi request reprint Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism
    Ami Klin
    Yale Child Study Center, Yale University, 230 S Frontage Rd, New Haven, CT 06520, USA
    Arch Gen Psychiatry 59:809-16. 2002
    ..Enhanced ecological validity was intended to maximize between-group effect sizes and assess the predictive utility of experimental variables relative to outcome measures of social competence...
  11. ncbi request reprint A normed study of face recognition in autism and related disorders
    A Klin
    Yale Child Study Center, New Haven Connecticut 06520, USA
    J Autism Dev Disord 29:499-508. 1999
    ..Contrary to our expectation, children with PDDNOS did not show face recognition deficits...
  12. ncbi request reprint Defining and quantifying the social phenotype in autism
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Psychiatry 159:895-908. 2002
    ..Genetic and neurofunctional research in autism has highlighted the need for improved characterization of the core social disorder defining the broad spectrum of syndrome manifestations...
  13. doi request reprint Embracing the challenge of bold theories of autism
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Br J Psychol 100:29-32. 2009
    ..This article is a commentary on 'Fetal testosterone and autistic traits' (Auyeung et al., 2009)...
  14. ncbi request reprint Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome
    R T Schultz
    Child Study Center, Yale University, New Haven, Conn 06520 7900, USA
    Arch Gen Psychiatry 57:331-40. 2000
    ..Therefore, it is of considerable interest that individuals with autism and related conditions have selective deficits in face recognition (sparing nonface object recognition)...
  15. ncbi request reprint Verbal bias in recognition of facial emotions in children with Asperger syndrome
    J B Grossman
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    J Child Psychol Psychiatry 41:369-79. 2000
    ..e., words over faces). Thus, children with AS may be utilizing compensatory strategies, such as verbal mediation, to process facial expressions of emotion...
  16. ncbi request reprint Higher-functioning pervasive developmental disorders: rates and patterns of psychotropic drug use
    A Martin
    Child Study Center, Yale University School of Medicine, New Haven, CT, USA
    J Am Acad Child Adolesc Psychiatry 38:923-31. 1999
    ..To explore the frequency, characteristics, and associated target symptoms of psychotropic drug use among subjects with higher-functioning pervasive developmental disorders (HFPDDs)...
  17. ncbi request reprint Educational placements and service use patterns of individuals with autism spectrum disorders
    SUSAN WILLIAMS WHITE
    Virginia Treatment Center for Children, School of Medicine, Virginia Commonwealth University, 515 North 10th Street, Richmond, Virginia 23298, USA
    J Autism Dev Disord 37:1403-12. 2007
    ..Findings highlight the emphasis placed on certain child characteristics (e.g., cognitive ability), with far less emphasis on other areas (e.g., degree of social deficit), in educational placement and service provision...
  18. ncbi request reprint Asperger's syndrome
    James McPartland
    Yale Child Study Center, New Haven, CT 06520, USA
    Adolesc Med Clin 17:771-88; abstract xiii. 2006
    ..Existing research is reviewed within the areas of epidemiology, medical/neurobiologic factors, genetics, and outcome, and future directions for research are recommended...
  19. ncbi request reprint Studying the emergence of autism spectrum disorders in high-risk infants: methodological and practical issues
    Lonnie Zwaigenbaum
    Department of Paediatrics, McMaster Children s Hospital at McMaster University, Hamilton, Ontario, Canada
    J Autism Dev Disord 37:466-80. 2007
    ..We suggest possible design and implementation strategies to address these various challenges, based on current research efforts in the field and previous studies involving high-risk populations...
  20. ncbi request reprint Brief report: relations between prosodic performance and communication and socialization ratings in high functioning speakers with autism spectrum disorders
    Rhea Paul
    Yale Child Study Center, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 35:861-9. 2005
    ..They suggest the need for careful assessment of inappropriate prosody and voice features in speakers with ASD, and for effective intervention programs aimed at reducing the stigmatization of individuals with these conditions...
  21. doi request reprint Absence of preferential looking to the eyes of approaching adults predicts level of social disability in 2-year-old toddlers with autism spectrum disorder
    Warren Jones
    Yale Child Study Center, Yale University School of Medicine, 230 S Frontage Rd, New Haven, CT 06520, USA
    Arch Gen Psychiatry 65:946-54. 2008
    ..For children with autism, however, diminished and aberrant eye contact is a lifelong hallmark of disability...
  22. ncbi request reprint Brief report: social and communication abilities and disabilities in higher functioning individuals with autism and Asperger syndrome
    Celine A Saulnier
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 37:788-93. 2007
    ..No relationship was found between adaptive functioning and symptom severity...
  23. ncbi request reprint Autism spectrum disorder in the second year: stability and change in syndrome expression
    Katarzyna Chawarska
    Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    J Child Psychol Psychiatry 48:128-38. 2007
    ....
  24. pmc The modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disorders
    Jamie M Kleinman
    Department of Psychology, University of Connecticut, 406 Babbidge Rd, Storrs, CT 06269 1020, USA
    J Autism Dev Disord 38:827-39. 2008
    ..Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD...
  25. ncbi request reprint Reliability of the ADI-R: multiple examiners evaluate a single case
    Domenic V Cicchetti
    Child Study Center, Yale University School of Medicine, New Haven, CT, USA
    J Autism Dev Disord 38:764-70. 2008
    ..62 and 0.68); and in fair agreement on 3% (82 - 84%, with K(w) between .40 and .47). For the remaining 10% of ADI-R items, examiners showed poor agreement (50-81% with K(w )between -.67 and .37)...
  26. ncbi request reprint Parental recognition of developmental problems in toddlers with autism spectrum disorders
    Katarzyna Chawarska
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT, 06520, USA
    J Autism Dev Disord 37:62-72. 2007
    ..Later AOR was associated with poorer social-communicative and nonverbal cognitive functioning at 2 and 4. The findings are discussed in a context of identifying distinct developmental trajectories within the autism spectrum...
  27. doi request reprint In the eye of the beholden: tracking developmental psychopathology
    Ami Klin
    J Am Acad Child Adolesc Psychiatry 47:362-3. 2008
  28. pmc The structure of intelligence in children and adults with high functioning autism
    Gerald Goldstein
    VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania 15206, USA
    Neuropsychology 22:301-12. 2008
    ..Findings suggest similar organization of cognitive abilities in HFA, but with the possibility of underconnectivity or reduced communication among brain regions in autism...
  29. pmc Disruption of Contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome
    Thomas Fernandez
    Am J Hum Genet 82:1385. 2008
  30. doi request reprint Altered face scanning and impaired recognition of biological motion in a 15-month-old infant with autism
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, USA
    Dev Sci 11:40-6. 2008
    ....
  31. ncbi request reprint Asperger's syndrome: a comparison of clinical diagnoses and those made according to the ICD-10 and DSM-IV
    Marc Woodbury-Smith
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    J Autism Dev Disord 35:235-40. 2005
    ..It is suggested that this is due to limitations inherent in these criteria, and alternative conceptualizations are discussed...
  32. ncbi request reprint Perception and production of prosody by speakers with autism spectrum disorders
    Rhea Paul
    Southern Connecticut State University, USA
    J Autism Dev Disord 35:205-20. 2005
    ..The implications of these findings for understanding prosodic deficits is speakers with autism spectrum disorders, and for future research in this area, are discussed...
  33. ncbi request reprint Autism and pervasive developmental disorders
    Fred R Volkmar
    Child Study Center, Yale University, New Haven, CT 06520, USA
    J Child Psychol Psychiatry 45:135-70. 2004
    ..Significant challenges lie ahead in evaluating the growing number of treatments for autism and in integrating the results of research into treatment and educational settings...
  34. ncbi request reprint Annotation: Hyperlexia: disability or superability?
    Elena L Grigorenko
    Child Study Center, Yale University, New Haven, CT 06510, USA
    J Child Psychol Psychiatry 44:1079-91. 2003
    ..Hyperlexia is the phenomenon of spontaneous and precocious mastery of single-word reading that has been of interest to clinicians and researchers since the beginning of the last century...
  35. ncbi request reprint Automatic attention cueing through eye movement in 2-year-old children with autism
    Katarzyna Chawarska
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Child Dev 74:1108-22. 2003
    ..Cue-specific differences in performance related to the level of engagement and cue-processing time may suggest reliance on different underlying strategies for gaze processing in autism...
  36. ncbi request reprint Concurrent validity and classification accuracy of the Leiter and Leiter-R in low-functioning children with autism
    Katherine D Tsatsanis
    Yale University, Yale Child Study Center, USA
    J Autism Dev Disord 33:23-30. 2003
    ..However, because of changes in the design of the Leiter-R, there may be greater clinical success with the original Leiter for those children who are very low functioning and severely affected, particularly younger children...
  37. pmc The role of the fusiform face area in social cognition: implications for the pathobiology of autism
    Robert T Schultz
    Child Study Center, Yale University School of Medicine, 230 S Frontage Road, New Haven, CT 06520 7900, USA
    Philos Trans R Soc Lond B Biol Sci 358:415-27. 2003
    ..From this perspective, the literature on hypoactivation of the FFA in autism may be interpreted as a reflection of a core social cognitive mechanism underlying the disorder...
  38. ncbi request reprint Asperger syndrome
    Ami Klin
    Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, USA
    Child Adolesc Psychiatr Clin N Am 12:xiii-xvi. 2003
  39. ncbi request reprint Genetics of childhood disorders: XLIII. Autism, part 2: neural foundations
    Robert T Schultz
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    J Am Acad Child Adolesc Psychiatry 41:1259-62. 2002
  40. ncbi request reprint A descriptive study of hyperlexia in a clinically referred sample of children with developmental delays
    Elena L Grigorenko
    Department of Psychology, Child Study Center, Yale University, New Haven, CT 06520 8205, USA
    J Autism Dev Disord 32:3-12. 2002
    ..The range of IQ and other cognitive skills and the developmental outcomes of children with hyperlexia were comparable to those of children without hyperlexia...
  41. pmc Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome
    Thomas Fernandez
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Hum Genet 74:1286-93. 2004
    ..Our results demonstrate the association of CNTN4 disruption with the 3p deletion syndrome phenotype and strongly suggest a causal relationship. These findings point to an important role for CNTN4 in normal and abnormal CNS development...
  42. ncbi request reprint Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism network
    Sally Ozonoff
    Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA
    J Autism Dev Disord 34:139-50. 2004
    ....
  43. ncbi request reprint Adaptive behavior in autism and Pervasive Developmental Disorder-Not Otherwise Specified: microanalysis of scores on the Vineland Adaptive Behavior Scales
    Rhea Paul
    Yale Child Study Center, PO Box 207900, New Haven, CT 06520 7900, USA
    J Autism Dev Disord 34:223-8. 2004
    ..Implications of these findings for both diagnosis and intervention with children with Autism Spectrum Disorders will be discussed...
  44. ncbi request reprint When Asperger's syndrome and a nonverbal learning disability look alike
    Martin T Stein
    University of California San Diego, San Diego, California, USA
    J Dev Behav Pediatr 25:190-5. 2004
  45. ncbi request reprint When Asperger's syndrome and a nonverbal learning disability look alike
    Martin T Stein
    University of California San Diego, San Diego, California, USA
    J Dev Behav Pediatr 25:S59-64. 2004
  46. ncbi request reprint Deficits in social attribution ability in Prader-Willi syndrome
    Kathleen Koenig
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    J Autism Dev Disord 34:573-82. 2004
    ....
  47. ncbi request reprint Source memory in children with autism spectrum disorders
    Angela Garcia O'Shea
    Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06510, USA
    Dev Neuropsychol 27:337-60. 2005
    ....
  48. ncbi request reprint Autism in infancy and early childhood
    Fred Volkmar
    Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Annu Rev Psychol 56:315-36. 2005
    ..New approaches to screening have lowered the age of initial diagnosis; this presents new challenges for early intervention. Directions for future research are highlighted...
  49. ncbi request reprint What's so special about Asperger Syndrome?
    Simon Baron-Cohen
    Brain Cogn 61:1-4. 2006
  50. ncbi request reprint [Autism and the pervasive developmental disorders]
    Ami Klin
    Rev Bras Psiquiatr 28:S1-2. 2006
  51. ncbi request reprint Reduced thalamic volume in high-functioning individuals with autism
    Katherine D Tsatsanis
    Yale Child Study Center, Yale University, New Haven Connecticut 06520 7900, USA
    Biol Psychiatry 53:121-9. 2003
    ..In this study, specific consideration is given to a role for the thalamus in autism...
  52. ncbi request reprint [Autism and Asperger syndrome: an overview]
    Ami Klin
    Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Rev Bras Psiquiatr 28:S3-11. 2006
    ..This overview focuses on the history, nosology, and the clinical and associated features of the two most well-known pervasive developmental disorders - autism and Asperger syndrome...
  53. pmc Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders
    Betul Bakkaloglu
    Program on Neurogenetics, Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Hum Genet 82:165-73. 2008
    ....
  54. pmc Disruption of neurexin 1 associated with autism spectrum disorder
    Hyung Goo Kim
    Molecular Neurogenetics Unit, Center for Human Genetic Research and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Hum Genet 82:199-207. 2008
    ....

Research Grants11

  1. Eye-Tracking Studies of Social Visual Pursuit in Autism
    Ami Klin; Fiscal Year: 2006
    ..The proposed R01 works synergistically with other ongoing eye-tracking research including studies of toddlers at risk of having autism and studies of monkeys with mesiofrontal-limbic ablations. ..
  2. Perception of Social and Physical Contingencies in Infants with ASD
    Ami Klin; Fiscal Year: 2010
    ....
  3. The Ontogeny of Social Visual Engagement in Infants at Risk for Autism
    Ami Klin; Fiscal Year: 2009
    ..Like the Committee's action items, this project emphasizes developmental markers and screening in infants, as well as neurodevelopmental processes, and is, therefore, highly relevant to public health. ..
  4. The Ontogeny of Social Visual Engagement in Infants at Risk for Autism
    Ami Klin; Fiscal Year: 2010
    ..Like the Committee's action items, this project emphasizes developmental markers and screening in infants, as well as neurodevelopmental processes, and is, therefore, highly relevant to public health. ..