Tae Hoon Kim

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093 0653, USA
    Cell 128:1231-45. 2007
  2. ncbi A high-resolution map of active promoters in the human genome
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, California 92093-0653, USA
    Nature 436:876-80. 2005
  3. ncbi Genome-wide analysis of protein-DNA interactions
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, University of California, San Diego School of Medicine, La Jolla, California 92093 0653, USA
    Annu Rev Genomics Hum Genet 7:81-102. 2006
  4. ncbi Direct isolation and identification of promoters in the human genome
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA
    Genome Res 15:830-9. 2005
  5. ncbi Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells
    Ping Sun
    Burnham Institute for Medical Research, La Jolla, CA 92037, USA
    Mol Pharmacol 69:520-31. 2006
  6. ncbi An all-round view of eukaryotic transcription
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0653, USA
    Genome Biol 7:323. 2006
  7. ncbi Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    Ewan Birney
    Nature 447:799-816. 2007
  8. ncbi ChIP-chip for genome-wide analysis of protein binding in mammalian cells
    Tae Hoon Kim
    Yale University School of Medicine, New Haven, Connecticut, USA
    Curr Protoc Mol Biol . 2007

Research Grants

  1. Analysis of higher order chromatin structures in normal and cancer epigenomes
    Tae Hoon Kim; Fiscal Year: 2010

Collaborators

Detail Information

Publications8

  1. ncbi Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093 0653, USA
    Cell 128:1231-45. 2007
    ..In addition, CTCF localization is largely invariant across different cell types. Our results provide a resource for investigating insulator function and possible other general and evolutionarily conserved activities of CTCF sites...
  2. ncbi A high-resolution map of active promoters in the human genome
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, California 92093-0653, USA
    Nature 436:876-80. 2005
    ..These results provide a global view of the functional relationships among transcriptional machinery, chromatin structure and gene expression in human cells...
  3. ncbi Genome-wide analysis of protein-DNA interactions
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, University of California, San Diego School of Medicine, La Jolla, California 92093 0653, USA
    Annu Rev Genomics Hum Genet 7:81-102. 2006
    ..Here, we review recent advances in ChIP-based methods for genome-wide detection of protein-DNA interactions, and discuss their significance in enhancing our knowledge of the gene regulatory networks and epigenetic mechanisms in cells...
  4. ncbi Direct isolation and identification of promoters in the human genome
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA
    Genome Res 15:830-9. 2005
    ..These results demonstrate the specificity of a genome-wide analysis method for mapping transcriptional regulatory elements and also indicate that a small, yet significant number of human genes remains to be discovered...
  5. ncbi Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells
    Ping Sun
    Burnham Institute for Medical Research, La Jolla, CA 92037, USA
    Mol Pharmacol 69:520-31. 2006
    ..The positive inter-regulation between beta-cat/Tcf-4 signaling and ET-1 signaling potentiates proliferation and survival of CaP cells, thereby representing a novel mechanism that contributes to CaP progression...
  6. ncbi An all-round view of eukaryotic transcription
    Tae Hoon Kim
    Ludwig Institute for Cancer Research, University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0653, USA
    Genome Biol 7:323. 2006
    ..A report of the Keystone Symposium 'Regulation of Eukaryotic Transcription: From Chromatin to mRNA', Taos, USA, 21-26 April 2006...
  7. ncbi Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    Ewan Birney
    Nature 447:799-816. 2007
    ..Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function...
  8. ncbi ChIP-chip for genome-wide analysis of protein binding in mammalian cells
    Tae Hoon Kim
    Yale University School of Medicine, New Haven, Connecticut, USA
    Curr Protoc Mol Biol . 2007
    ..UNIT 21.9 describes a protocol for analysis of protein-DNA interactions in yeast cells. This unit introduces an alternative protocol developed for mammalian cells...

Research Grants1

  1. Analysis of higher order chromatin structures in normal and cancer epigenomes
    Tae Hoon Kim; Fiscal Year: 2010
    ....